| Definition | Mycobacterium leprae Br4923 chromosome, complete genome. |
|---|---|
| Accession | NC_011896 |
| Length | 3,268,071 |
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The map label for this gene is ppsB [H]
Identifier: 221230747
GI number: 221230747
Start: 2799302
End: 2804770
Strand: Reverse
Name: ppsB [H]
Synonym: MLBr_02354
Alternate gene names: 221230747
Gene position: 2804770-2799302 (Counterclockwise)
Preceding gene: 221230748
Following gene: 221230746
Centisome position: 85.82
GC content: 61.47
Gene sequence:
>5469_bases ATGACGAGCTTGGCAGAGCGTGCGGCGCAGCTGTCGCCGAACGCGCGCGCGGCACTGGCACGCGAACTTGTCCGTACCGG GACTGCTTTCCCAACCGACATTTCAGAGCCAGTCGCGGTGGTGGGCATCGGATGTCGTTTCCCGGGGAATGTAACTGGCC CGGATAGTTTTTGGCAGCTGTTGGTCGATGGCGGGGACGCGATCAGCGAAGTTCCGCCAGATCGGTGGGATGCGGATGCG TTCTACGATCCCGACCCGTCGGCGTCAGGGCGGATGACGACGAAATGGGGCGGCTTCGTTCCCGACGTTGATGCTTTCGA CGCCGAGTTCTTTGGCATCACACCTCGCGAAGCCGTGGCGATGGATCCGCAGCATCGGATGCTGCTCGAGGTTGCCTGGG AATCCCTTGAGCACGCCGGCATTGCACCGGATTCGCTGAGCGGCACTCGAACTGCGGTGATGATGGGACTTTCCTCGTGG GACTACACGATCGTCAACATCGAGCGCAGAGCCGATATCGATGCCTACCTGAGCACCGGAACTCCGCATTGCGCGGCAGT AGGACGGATCTCGTATTTGTTAGGATTGCGTGGTCCGGCGATGGCCGTGGACACTGCGTGCTCGTCGTCGCTGGTGGCAA TCCACCTGGCTTGTCAGAGCTTACGGTTGCGTGAGAGTGACGTGGCATTAGCCGGCGGTGTGCAGCTCATCTTGTCGCCT TTCACCGCCATCGCGTTGTCCAAGTGGTCGGCGTTATCACCGACCGGACGATGCAATAGTTTCGATGCCAATGCGGATGG ATTCGTGCGTGGCGAAGGTTGCGGAGTAGTGGTGCTAAAACGGCTAGTTGACGCGCTGCGCGACCAGGATCGTGTGCTGG CTGTGGTTCGTGGTTCGGCGACCAATCAAGACGGTCGGTCCAACGGCATGACCGCGCCTAACGCGCTGGCGCAGCGCGAC GTTATTACTACCGCCTTGCGGCTCGCGGATATCACCCCAGACAGCGTTAACTATGTTGAAACACATGGAACCGGAACAGT GTTGGGAGACCCTATCGAGTTCGAATCGCTGGCTGCCACTTACGGCCGCGGCGAAAGCTCCTGTGCTTTGGGGTCGGTCA AGACCAACATCGGCCATCTAGAGGCTGCCGCCGGAGTGGCCGGATTCATCAAGACGGTGCTGGCGTTGCAGCACGCGTAC ATTCCGCGTAATGTCCACTTTACTCAATGGAACCCGGCCATCGACGCATCCACGACTCGGCTGTTTGTGCCCACTGAGAG CGCACCATGGCCGGCAATTCCGGGCCCGCGTCGTGGAGCGGTGTCATCGTTCGGGCTCAGTGGGACTAACGCCCATGTAG TGATTGAGCAGGCGCCAGACACGACTGTACCTATATCGGCAGCTGTTGGTAGGCAGTATGTTTCGGCTCTGGTGGTGTCG GGTAAGACTGTTACGCGGGTGGCGTCGGCAGCCGCAGTGTTGGCTGACTGGATGTCGGGACCGGGCGCGGCGGCACCACT CGCCGACGTGGCGTACACGCTGAACCAGCACCGGGTTCGGCACCCCAAGTTGGCAACCGTGATTGCGCGTGATCACGCGG ATGCCGTTGCGGGGTTACGGGCGCTGGCGGCCGGACAGCCACGAGTGGGAGTGGTGGGTTGTGATCAGCATGCAGCTGGG CCCGGTCGAGTTTTTGTGTATTCGGGTCAGGGCTCGCAGTGGGCCGGGATGGGTAGGCAGCTGCTGGTCGATGAGCCGGC CTTCGCCAAGGCGGTAGCTGAACTGGAGCCCACGTTCGTTGCTCAGGTAGGTTTTTCGCTGGAGCATACACTCGCCTATG GCGACGAGGTGGTAGGTATCGAACGCATTCAGCCGGTGCTGGTGGGGATCCAGCTGGCGCTCACCGAGTTGTGGCGTTCT TACGGGGTGACTCCGGATGCTGTGATTGGGCACTCGATGGGTGAGGTGTCCGCGGCAGTGGTAGCCGGCGCGTTGACGCC CGAGCAGGGCTTGCGGGTGATCGCTACCCGGTCCCGGCTGATGGCGCGTCTGTCGGGTCAGGGCGCGATGGCATTGCTAG AGTTGGACGCCGACGCCGCCGAGGCTCTGATTGCTGACTACCCTGAGGTGACGTTGGCAGTGTACGCTTCGCCACGCCAA TCGGTGATTGCCGGCTTGCCGGAGTCGGTGGATGCGGTGATATCGGTGGTGGCGGAGCAGAATCGGTTAGCGCGCCGCGT CGATGTCGAGGTGGCTTCGCACCATTCGATCATAGATCCGATTCTGCCCGAGTTGCGAAATGCGCTAGCGGATTTGGTTC CGCAGACGCCGATCATCCCGATAATCACCACCACTCACGAACACACCCAGGCGGTGATGGACGCCGACTATTGGGCGGCT AACCTGCGCAACCCGGTGCGATTCCACCAGGCCATCGCACAGGCTGTTAGCGGCGTCGGTGGATTCAATCGTACCTGCCA CTCTTTCATCGAGATCAGCCCCCACCCCGTGCTCACACACGCTATCACTGACACCGTCGGCGGGTCCGGAGGCCATGTTG TCACGTCGGCGATGAACCGCGACCTCGACCAGACCCTGTTCTTCCACGCCCAACTTGCCACCGTCGGGGTGACCGAGTCG GATAGCGCCAAGGGTCGATTGGTGGACCTGCCACCCACGCCGTGGCAACATTCGCGATTCTGGGTTGCGGATCGATCAGC GATGTCGGAGCTGGCCGTGGCCCACCCGTTGCTCGGTGTGCATGTCGAAATGCCCGGCAGTGGAGACCACGGCTGGCAGG CAGATGTCGGAACCGACGTATGTCCCTGGCTAGCTGACCATAAGGTATTCGGCCAGCCTATTATGCCGGCTGCTGCGTTT GCTGAGATCGCTGTGGCGGCGGCCAGCGAAGCGCTCGGTGTACCCGCTGGCACTTCTGGGGCCAATATTGTAATCCACCA GTTCGAGGTCGAGCAAATGCTTTCCCTCGACAACCACACACCGCTCACGACGCAGTTGACCTATCACGGGAACAGCAAAA TTCGGGTCGAGATCTATTCTCGCTCACCTCGCGGTGATTTCTCTCGGCACGCCACGGCCAATGTTGAGCATGTATCGCAC AATGCCGTGCAGCCGTTCCAGCAAGCACCCGGTTCTTCGAACGGGGTAACCGTGTCTCCAGCCGATTTCTACGCTGTGCT ACGGCAGACTGGTCAACACCATGGCCCGGTGTTTGCTGTCTTGACCCGGATAACTCGGCTGCTTGACGGTTCCGCGGAAA CCGAGATCACTCTTCCCGACGAGGTTCCCCGGCATCCCGGATATCGACTCCATCCCGTTGTACTAGATGCGGCATTGCAA AGCGTCGGTGCCGCAATACCTGACGGTGAGGTCGCTGAGTCGGCGGAAGTCAGCTACCTGCCGGTGTCGTTCGAGGCGAT CCGAGTGTACCGCGACATCGGTCGGCACGCCCTGTGTCGGGCACGTTTGACCAACCTCGACGGGGGTACCGGCAAGTTGG GCAAGATCGTCTTGATTGACGACGCTGGTTACGTAGCAGCCGAAGTGGATGGCATTTACTTGCGACGTATTGAACGCCGT GTGGTGCCATTACCGTTGGCGCAGAAGATCTTCGACGCTGAGTGGATCGAAAGCCCGATCCCGGCTTCGCGAGCTTTGGA GCAGATTACCGAGACAGCGCGCGCAAGTTGGTTGGTACTTACCGACTGGGATCCTTCGATCAAATCCCTGACAGACGAAT TCATTGCGAGATGGCGCTCACCAATGCGACGGGTGTACACTGCAAATCTCCACGACGAATCGGCGATGCTTGCCGCATTC GCAGAGACGGCGGGTGATCCAGAGCACCCACCTATTGGCGTGGTCATCTTCGTCGGCGGTGCGGCAACCGGGCTGGACGA TGGGCTGGTGCAAGCGCGAGACTCGGTGTGGTCGATCTCGACTGTCGTTCGTGCGATCGTAAGTACGTGGCATGGCCGAT CGCCACGGCTGTGGTTGATCGCCGGTGGTGGTCTTTCCGTTCAGGATGACGAGCTGGGGGCTCCCGCGACGGCTGCTTTG AAGGGCCTGGTGCGAGTGCTGGCCCTGGAGAATCCGGACCTGCGCGCCACCCTGCTCGATCTGGATGCCACGCAAGATCA GATCGCAGCACTGACTGCAGAATTGCACAATTCTGCGAGCGAGTTCGGTGGCGATGATGTGATCGCGTGGCGGGGTCAAC ACAGATTCGTCGAACGGCTGTGTAAGGCCACATTGGATGCTGGCAAAGACAATCCTGTGGTTCGCCCCGGAGCGGCATAC ATCGTGACGGGTGGTCTTGGTGGCCTTGGCTTAGTCGTTGCCAGATGGTTGGTAGATCGCGGTGCCGGCCGGGTGGTCCT GGGCAGCCGCAGCGACCCCACCGAGGAGCAGCGCAAAACTCTGGTCGAATTGGAAGCTCGTGCCGAAATTGTGTTTTTGC GCGGCGATGTGACGTCGCCAGGTGTGGCCGAGAGTCTGGTCGCGGCGGCAGGACGAGCGGGCGGCCAGTTGCGCGGCATC GTGCACGGTGCGGCGGTCATCGAAGACAGTCTGGTGTTCACCATGACCAGAGAAAACTTGGAGCGAGTTTGGGCGCCTAA GGCCACTGGCGCGCTGCGGATGCACCAGGCCAGCGTTAGCTGCGAGCTCGACTGGTGGTTGGGGTTTTCCTCTGTTGCTT CGCTCTTGGGCTCGCCCGGACAAGCGGCATATGCATGTGCCAGTGCATGGCTCGACGCTCTGGTCATGTGGCGCAAGGCA TCCGGTTTGCCATCGGCGGTGATCAACTGGGGTCCGTGGTCAGATGTGGGTGTCGCCCAGGCTTTGGTAGGCAGTGTTCT AGATACAATCACTCCGGCAGAGGGCATCGAGGCTATCGACTCGTTGCTGGCTGCCGGTCGGACTCGCACGGGCGTTGCCC GGTTACGTGCCGATAAGGCTCTGGTCGCATTCCCGGAGATGCGTAGCATCAGCTACTTCACCTGGGTGGTCGAGCAGCTG GCCGCGGCGGGTGACCTGGGTGACTGGGTCGGGTCCGACACGCTTGCCGATCTCGATCCGGCAGAGGCCCAGCGCGTGGT GACCGAGCGGATGTGCGCGCTTATCGCGGCGGTTATGGGTTACGCTGACCGATCAACAGTTAATCCTGCTGTGCCGTTGA CCGAGCTGGGGCTGGACTCCCTGATGGCGGTGCGGATCCGTAACGGTGCACGGGCGGACTTCGGCGTGGAGCCGCCGGTG ACATTGATTTTGCAGGGCGCGTCCCTGCAAGACTTGACCGCCGATGTTGTGCGTCAACTTGGGCTCGCGGGCCCAAAGCA GGCGCTCGAGAACGCTGACACCGTTCGCGACCGCGTTCAGCAGCGTGCGGCGGTGCGACGTGGAGCCGTGATGCGGCGCC GACCTAAACCTGACGTACAGGGAGGATAG
Upstream 100 bases:
>100_bases AGGCGACTGACACAAACGCGGAACTGTCCAAAGCGGAGATGGACCTGCTCTCTGATCTGGTCGAAGCCAGCGAGCTGGAA GCTGCAACGAGAGGCGAGTC
Downstream 100 bases:
>100_bases AAACCAGTGATTACCCCCGACAACGCGATCGCGGTGGTCGGCATGGCCGGCAAATTTCCGGGCGCCAACGATGTGTCGGC GTTCTGGACCAACCTTCGGC
Product: polyketide synthase
Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 1822; Mature: 1821
Protein sequence:
>1822_residues MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQLLVDGGDAISEVPPDRWDADA FYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVAMDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSW DYTIVNIERRADIDAYLSTGTPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSATNQDGRSNGMTAPNALAQRD VITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAATYGRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAY IPRNVHFTQWNPAIDASTTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSALVVS GKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAVAGLRALAAGQPRVGVVGCDQHAAG PGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELEPTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRS YGVTPDAVIGHSMGEVSAAVVAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYASPRQ SVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIPIITTTHEHTQAVMDADYWAA NLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHPVLTHAITDTVGGSGGHVVTSAMNRDLDQTLFFHAQLATVGVTES DSAKGRLVDLPPTPWQHSRFWVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPIMPAAAF AEIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIRVEIYSRSPRGDFSRHATANVEHVSH NAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHHGPVFAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQ SVGAAIPDGEVAESAEVSYLPVSFEAIRVYRDIGRHALCRARLTNLDGGTGKLGKIVLIDDAGYVAAEVDGIYLRRIERR VVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDEFIARWRSPMRRVYTANLHDESAMLAAF AETAGDPEHPPIGVVIFVGGAATGLDDGLVQARDSVWSISTVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAAL KGLVRVLALENPDLRATLLDLDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKATLDAGKDNPVVRPGAAY IVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVELEARAEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGI VHGAAVIEDSLVFTMTRENLERVWAPKATGALRMHQASVSCELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKA SGLPSAVINWGPWSDVGVAQALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVAFPEMRSISYFTWVVEQL AAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYADRSTVNPAVPLTELGLDSLMAVRIRNGARADFGVEPPV TLILQGASLQDLTADVVRQLGLAGPKQALENADTVRDRVQQRAAVRRGAVMRRRPKPDVQGG
Sequences:
>Translated_1822_residues MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQLLVDGGDAISEVPPDRWDADA FYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVAMDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSW DYTIVNIERRADIDAYLSTGTPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSATNQDGRSNGMTAPNALAQRD VITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAATYGRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAY IPRNVHFTQWNPAIDASTTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSALVVS GKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAVAGLRALAAGQPRVGVVGCDQHAAG PGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELEPTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRS YGVTPDAVIGHSMGEVSAAVVAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYASPRQ SVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIPIITTTHEHTQAVMDADYWAA NLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHPVLTHAITDTVGGSGGHVVTSAMNRDLDQTLFFHAQLATVGVTES DSAKGRLVDLPPTPWQHSRFWVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPIMPAAAF AEIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIRVEIYSRSPRGDFSRHATANVEHVSH NAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHHGPVFAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQ SVGAAIPDGEVAESAEVSYLPVSFEAIRVYRDIGRHALCRARLTNLDGGTGKLGKIVLIDDAGYVAAEVDGIYLRRIERR VVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDEFIARWRSPMRRVYTANLHDESAMLAAF AETAGDPEHPPIGVVIFVGGAATGLDDGLVQARDSVWSISTVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAAL KGLVRVLALENPDLRATLLDLDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKATLDAGKDNPVVRPGAAY IVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVELEARAEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGI VHGAAVIEDSLVFTMTRENLERVWAPKATGALRMHQASVSCELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKA SGLPSAVINWGPWSDVGVAQALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVAFPEMRSISYFTWVVEQL AAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYADRSTVNPAVPLTELGLDSLMAVRIRNGARADFGVEPPV TLILQGASLQDLTADVVRQLGLAGPKQALENADTVRDRVQQRAAVRRGAVMRRRPKPDVQGG >Mature_1821_residues TSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQLLVDGGDAISEVPPDRWDADAF YDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVAMDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSWD YTIVNIERRADIDAYLSTGTPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSPF TAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSATNQDGRSNGMTAPNALAQRDV ITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAATYGRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAYI PRNVHFTQWNPAIDASTTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSALVVSG KTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAVAGLRALAAGQPRVGVVGCDQHAAGP GRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELEPTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRSY GVTPDAVIGHSMGEVSAAVVAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYASPRQS VIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIPIITTTHEHTQAVMDADYWAAN LRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHPVLTHAITDTVGGSGGHVVTSAMNRDLDQTLFFHAQLATVGVTESD SAKGRLVDLPPTPWQHSRFWVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPIMPAAAFA EIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIRVEIYSRSPRGDFSRHATANVEHVSHN AVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHHGPVFAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQS VGAAIPDGEVAESAEVSYLPVSFEAIRVYRDIGRHALCRARLTNLDGGTGKLGKIVLIDDAGYVAAEVDGIYLRRIERRV VPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDEFIARWRSPMRRVYTANLHDESAMLAAFA ETAGDPEHPPIGVVIFVGGAATGLDDGLVQARDSVWSISTVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAALK GLVRVLALENPDLRATLLDLDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKATLDAGKDNPVVRPGAAYI VTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVELEARAEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGIV HGAAVIEDSLVFTMTRENLERVWAPKATGALRMHQASVSCELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKAS GLPSAVINWGPWSDVGVAQALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVAFPEMRSISYFTWVVEQLA AAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYADRSTVNPAVPLTELGLDSLMAVRIRNGARADFGVEPPVT LILQGASLQDLTADVVRQLGLAGPKQALENADTVRDRVQQRAAVRRGAVMRRRPKPDVQGG
Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]
COG id: COG3321
COG function: function code Q; Polyketide synthase modules and related proteins
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 acyl carrier domain [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=1105, Percent_Identity=26.9683257918552, Blast_Score=290, Evalue=1e-77, Organism=Homo sapiens, GI8923559, Length=276, Percent_Identity=30.0724637681159, Blast_Score=114, Evalue=6e-25, Organism=Homo sapiens, GI310129082, Length=105, Percent_Identity=30.4761904761905, Blast_Score=72, Evalue=5e-12, Organism=Homo sapiens, GI310109937, Length=105, Percent_Identity=30.4761904761905, Blast_Score=72, Evalue=5e-12, Organism=Homo sapiens, GI239744023, Length=105, Percent_Identity=30.4761904761905, Blast_Score=72, Evalue=5e-12, Organism=Escherichia coli, GI1787337, Length=435, Percent_Identity=26.2068965517241, Blast_Score=115, Evalue=3e-26, Organism=Escherichia coli, GI1788663, Length=270, Percent_Identity=28.5185185185185, Blast_Score=91, Evalue=7e-19, Organism=Escherichia coli, GI1787334, Length=301, Percent_Identity=29.5681063122924, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI212642053, Length=825, Percent_Identity=30.0606060606061, Blast_Score=306, Evalue=6e-83, Organism=Caenorhabditis elegans, GI17550940, Length=432, Percent_Identity=34.2592592592593, Blast_Score=229, Evalue=9e-60, Organism=Caenorhabditis elegans, GI71983541, Length=275, Percent_Identity=29.8181818181818, Blast_Score=110, Evalue=7e-24, Organism=Caenorhabditis elegans, GI71983535, Length=267, Percent_Identity=30.3370786516854, Blast_Score=108, Evalue=4e-23, Organism=Saccharomyces cerevisiae, GI6320904, Length=278, Percent_Identity=27.6978417266187, Blast_Score=105, Evalue=6e-23, Organism=Drosophila melanogaster, GI24581345, Length=1095, Percent_Identity=28.1278538812785, Blast_Score=322, Evalue=1e-87, Organism=Drosophila melanogaster, GI19920632, Length=1095, Percent_Identity=26.027397260274, Blast_Score=307, Evalue=4e-83, Organism=Drosophila melanogaster, GI221330659, Length=1095, Percent_Identity=26.2100456621005, Blast_Score=306, Evalue=8e-83, Organism=Drosophila melanogaster, GI24644341, Length=445, Percent_Identity=25.8426966292135, Blast_Score=108, Evalue=3e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR000794 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020801 - InterPro: IPR020841 - InterPro: IPR013968 - InterPro: IPR020806 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]
EC number: 2.3.1.41 [C]
Molecular weight: Translated: 193287; Mature: 193156
Theoretical pI: Translated: 5.44; Mature: 5.44
Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQL CCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH LVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVA HHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCCCCHHHC MDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSWDYTIVNIERRADIDAYLSTG CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHCCCC TPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP CCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEHHCCHHHHHHH FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA HHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCC TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAAT CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEECCCCCHHHHHHH YGRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAYIPRNVHFTQWNPAIDASTTR HCCCCCCEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEE LFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSALVVS EEEECCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHC GKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAVAGLR CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH ALAAGQPRVGVVGCDQHAAGPGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELEPTFV HHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHCCCHHH AQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRSYGVTPDAVIGHSMGEVSAAV HHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHH VAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYASPRQ HHCCCCHHHCCEEHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCCHH SVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIP HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEE IITTTHEHTQAVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHPVLTH EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEHH AITDTVGGSGGHVVTSAMNRDLDQTLFFHAQLATVGVTESDSAKGRLVDLPPTPWQHSRF HHHHCCCCCCCEEEHHHHCCCHHHHHHHHEEHHEEECCCCCCCCCEEEECCCCCCCCCEE WVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPIMPAAAF EEECHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHH AEIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIRVEIYS HHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHCCCCCCEEEEEEEECCCEEEEEEEE RSPRGDFSRHATANVEHVSHNAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHHGPVFAV CCCCCCCCCCCCCCHHHHCCHHCCHHHHCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHH LTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQSVGAAIPDGEVAESAEVSYL HHHHHHHHCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE PVSFEAIRVYRDIGRHALCRARLTNLDGGTGKLGKIVLIDDAGYVAAEVDGIYLRRIERR CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCHHHHHHHHHH VVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDEFIARWRS CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHH PMRRVYTANLHDESAMLAAFAETAGDPEHPPIGVVIFVGGAATGLDDGLVQARDSVWSIS HHHHHEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH TVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAALKGLVRVLALENPDLRATLLD HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE LDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKATLDAGKDNPVVRPGAAY CCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEECCCCCE IVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVELEARAEIVFLRGDVTSP EEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHEECCEEEEEEECCCCCC GVAESLVAAAGRAGGQLRGIVHGAAVIEDSLVFTMTRENLERVWAPKATGALRMHQASVS CHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHCCCCCCCCEEEEECCCE CELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKASGLPSAVINWGPWSDVGVAQ EEEHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCHHHHHH ALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVAFPEMRSISYFTWVVEQL HHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHH AAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYADRSTVNPAVPLTELGLDS HHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHH LMAVRIRNGARADFGVEPPVTLILQGASLQDLTADVVRQLGLAGPKQALENADTVRDRVQ HHHEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH QRAAVRRGAVMRRRPKPDVQGG HHHHHHHHHHHHCCCCCCCCCC >Mature Secondary Structure TSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQL CCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH LVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVA HHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCCCCHHHC MDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSWDYTIVNIERRADIDAYLSTG CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHCCCC TPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP CCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEHHCCHHHHHHH FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA HHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCC TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAAT CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEECCCCCHHHHHHH YGRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAYIPRNVHFTQWNPAIDASTTR HCCCCCCEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEE LFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSALVVS EEEECCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHC GKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAVAGLR CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH ALAAGQPRVGVVGCDQHAAGPGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELEPTFV HHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHCCCHHH AQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRSYGVTPDAVIGHSMGEVSAAV HHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHH VAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYASPRQ HHCCCCHHHCCEEHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCCHH SVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIP HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEE IITTTHEHTQAVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHPVLTH EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEHH AITDTVGGSGGHVVTSAMNRDLDQTLFFHAQLATVGVTESDSAKGRLVDLPPTPWQHSRF HHHHCCCCCCCEEEHHHHCCCHHHHHHHHEEHHEEECCCCCCCCCEEEECCCCCCCCCEE WVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPIMPAAAF EEECHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHH AEIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIRVEIYS HHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHCCCCCCEEEEEEEECCCEEEEEEEE RSPRGDFSRHATANVEHVSHNAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHHGPVFAV CCCCCCCCCCCCCCHHHHCCHHCCHHHHCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHH LTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQSVGAAIPDGEVAESAEVSYL HHHHHHHHCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE PVSFEAIRVYRDIGRHALCRARLTNLDGGTGKLGKIVLIDDAGYVAAEVDGIYLRRIERR CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCHHHHHHHHHH VVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDEFIARWRS CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHH PMRRVYTANLHDESAMLAAFAETAGDPEHPPIGVVIFVGGAATGLDDGLVQARDSVWSIS HHHHHEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH TVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAALKGLVRVLALENPDLRATLLD HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE LDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKATLDAGKDNPVVRPGAAY CCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEECCCCCE IVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVELEARAEIVFLRGDVTSP EEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHEECCEEEEEEECCCCCC GVAESLVAAAGRAGGQLRGIVHGAAVIEDSLVFTMTRENLERVWAPKATGALRMHQASVS CHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHCCCCCCCCEEEEECCCE CELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKASGLPSAVINWGPWSDVGVAQ EEEHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCHHHHHH ALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVAFPEMRSISYFTWVVEQL HHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHH AAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYADRSTVNPAVPLTELGLDS HHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHH LMAVRIRNGARADFGVEPPVTLILQGASLQDLTADVVRQLGLAGPKQALENADTVRDRVQ HHHEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH QRAAVRRGAVMRRRPKPDVQGG HHHHHHHHHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: None [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]
Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]
Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]
General reaction: Acyl group transfer [C]
Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]