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The map label for this gene is eryA [H]

Identifier: 221230746

GI number: 221230746

Start: 2794826

End: 2799295

Strand: Reverse

Name: eryA [H]

Synonym: MLBr_02353

Alternate gene names: 221230746

Gene position: 2799295-2794826 (Counterclockwise)

Preceding gene: 221230747

Following gene: 221230745

Centisome position: 85.66

GC content: 59.89

Gene sequence:

>4470_bases
GTGATTACCCCCGACAACGCGATCGCGGTGGTCGGCATGGCCGGCAAATTTCCGGGCGCCAACGATGTGTCGGCGTTCTG
GACCAACCTTCGGCGCGGCAAGGAGTCGATCGTCACCCTGTCTGAGCAAGAGCTGCGCGACAACGGGGTCAGCGACAAAG
CACTGGCCGATCCGGCGTATGTGCGTCGCGCACCGTTACTCGACGGGATCGACGAGTTTGATGCTGACTTCTTCGGTCTG
CCGCCGCTGGCCGCGCAGGTATTGGATCCACAACACCGGTTGTTCCTTCAGTGCGCGTGGCATGCGCTAGAGGATGCAGG
TTGTGACCCCGCGCAGTTCGACGGCTCGATCGGAGTATACGGAACCAGTTCTCCCAGCGGTTATCTCTTGCATAACCTGT
TGTCGCATCGCGACCCCCACACCGTTTTGGCTGAGGGACTCAACTTCGACCAGTTCAGTCTGTTCCTACAGAACGACAAA
GACTTCTTGGCAACTCGGATATCGCACGCGTTCAACTTGCGCGGCCCGAGTATTGCGGTTCAAACCGCGTGCTCGTCGTC
GCTCGTCGCGCTGCATCTGGCCTGCCTGAGTCTGCTGTCCGGCGAATGCGACATGGCACTGGCCGGCGGATCGTCGTTGT
GCATTCCGCACCGTGTCGGTTACTGGCACTCCCCGGGATCGATGGTCTCGGCTGTTGGCCACTGTCGGCCCTTCGACGTG
CGGGCCGACGGTACTGTCTTCGGCAGTGGTGTTGCGTTAGTGGCCCTCAAGCCGTTGCAGGCCGCCATCGACGCCAGCGA
CCGAATTCATGCCGTCATCCTCGGGTCAGCGATCAACAACGATGGATCCATGAAAATGGGTTACGCGGCGCCCAATCCTG
CCGCTCAAGCCGATGTCATCGCGGAAGCTCATGCGGTGGCCGGTATTGATTCGTCGACTGTGAGCTATGTCGAGACCCAT
GGAACCGGTACCCCGCTCGGGGACCCCATCGAAATCCAAGGGTTGAAAACGGCATTCGAAGTGTCGCAGATACCCCGCCC
GGGCCCATGTGTACTGGGGTCGGTCAAATCGAACATCGGCCACTTAGAAGTTGCCGCCGGAATCGCGGGTCTGATCAAAA
CGATTTTGTGCCTGAAGAACAAGGCGATTCCCGCGACGTTGCACTACACCAGTCCGAATCGGGAGCTGCGTCTGGACCAA
ACTCCGTTCGTCGTGCAAAGCAATTACGGCCCATGGAAGTGGGACGGCGTGCGTCGGGCAGGGGTCAGCTCGTTCGGGGT
CGGTGGTACCAACGTCCACGTCGTCTTGGAAGAAGCATCAGTTGAAGCATCCACTGTTGCTGCGTCGACCGGTCCCCAGG
TGATCCTTCTGTCAGCGCAAACCGCTGCGGCGCTTGGTGAATCGCGGGAAGCTCTGGCCACGGTGTTAGAAAAACCAGGC
GCACCGGACCTGTCCGACGTCGCTTATACGTTGGCCGGGCGCCGAAAGCACAACATCACGATGGCTGCCGTCGTCCGTGA
CCGGGAGCATGCGGTCACGGTTCTGCGGGCGGCCGAGCACGACAATGTTTTCGTTGGCGAATCCGGTGCTGATACCGGGC
GCAGTGCCGCCGCCTCAATCACCACCTTGGGGTCAGATCGCGTCGTTTTCCTGTTTCCCGGGCAAGGTGCTCAGCACGTT
GGAATGGCCAAAGGACTCTACGACACAGAGTCCGTCTTCGCTGAACACTTCGACACCTGTTCTGCCGGATTCCGCGAAGC
GATGGATGACCTGGATTTGCATTCGGCGATATTCAATGGTACCGCAATCGATCTGGAGCGCATCGACCGTTCGCAACCGG
CGCTGTTCACGGTGGAATACGCACTGGCGAAGTTGGTCGAAAGCTTTGGCGTAGGTGCCGGGGCCTACATCGGATACAGC
ACTGGCGAGTATATCGCAGCCACCTTGGCCGGGGTATTCGACCTCGAGACGGCGATCAAAACGGTGTCGTTGCGTGCCCG
TTTGATGCATGAGTCGCCGCCGGGAGCCATGGTTGCGGTGGCGCTGGGCCCCGAGGACATCACCGAGTACTTAGCAGAGT
ATTCTGCTAAGGGCGTCGAGTTGTCCGCCGTTAACGATCCCGGTAACTGCGTGGTCGCCGGGCCCAAAGACCAGATTCGC
GCGTTCAGCCAACGTCTTGACGAGGTGGGGATACCCGTACGTCGGGTCCGTGCCACTCATGCGTTCCATACAAGCTCGAT
GGAGCCTATGCTGAGAGAATTCTCCGAATTCCTTTCTCGTCAACAGCTTCGCGTTCCGAACACACCGTTGCTGAGCAACC
TCACCGGAACCTGGATGTCCGAGCAGCAGGTCACCGATCCGGAAAACTGGACACGTCAAATCAGTTCCACGATCCGCTTC
GCCGACGAGCTAGACGTGGTGCTGTCGCAATCCGGGCGAGTCCTTGTCGAAGTTGGTCCCGGTGGCAGCTTGACCGGTTC
GGCGATGCGTCACCCGAGGTGGTCGAGTGGGCACCGCGCTGTTCGGCTCATGCGCCATCCGCTTCAGAACGTTGATGACC
ACGACACGTTCCTGCGCGCACTGGGTGAACTCTGGTCGGCTGGAATCGAAGTTGACTGGGCGCCGCAGCGTTCGGTCATG
CCGCACCTCGTTTCCTTGCCCGGATATCCGTTTGCTCGACAACGTCATTGGGTCGAACCCCGATATACGATCTGGGCGCA
GATTCCCGGCGCGAGCAGTGGTTCGCCGGTTGACTCCAGCGTCGATTCCGCCACCGTTGAAGGGGTGCGAGGCGGGGAGT
CGCAGACTGAGGCCACGTTGCAGCGCATCTGGTCACAGTGCTTAGGTGTCAGTTCAGTAGATCGGAATGCCAATTTCTTT
GATCTAGGCGGCGACTCCTTGATGGCGATCAGCATCTCGATGGCCGCGGCCAACGAGGGTATGACCATCACACCGCAGGA
TATGTACGAGCACCCGACTCTGGCCTCGTTGACGGCTGCCGTCGATGCCTCATTCGCGTCGAGTGGGTTGGCGAAACCAC
CGGAGGCCGCGGCGCATCCGGCGGTTCCACCCAACATTGCTTACTTCCTCGAGCGGGGGTTGTGCGACACTGGCCGCTGG
CGCGTTCCATTGATCCTGCGGCTTGACCCCAAGATAGGGTCAGACGACATTCGAGCCGTGCTGACCGCAGTGGTCAATCA
CCACGACGTCTTGCGCCTCAGCCTCGTCGACAACGACGGAATGTGGGAACAGCACATCGCGGCGACCGGAGAATTCACTC
GGCTCTTGACCCAGACGCTTCCCGACGGTGTAGCCGCCGGCAGTGCAGAGGAACGGGCCGTGGTATCCAGTATTCTGGCC
GAACTCATTGCTAGTCAAAGTGATTTGAACGAGCCACTGACCGCCGTGCAGATCACAACCGCTCACGGTGGTCCGCACTA
TCTCGGTCTTGCCGTGCACCAGATGGTTATCGACGATGCATCGCGCCAAATCTTGGGGACCGATATCATCACCGCGTTTG
GGCAGCGGCTGGCCGGCGAGGAGATCACGCTGGAACCGGTCACCACTGGGTGGCGGGAATGGTCACTGCGCTGCGCGGCC
CTTGCGACGCATCCGGCAGCCCTCGACACTCGCTCTTTTTGGATCGAGAATGCGAACAAGGTGAACTTGTGGTTGGCTGA
TGTCTCGCTCAATACAGATGTTATTCAACCGCCCGGTGCCGACGATCTGATTAGGATGCCGTGCACGCTAAGCGTTGAGC
AGACGTCCGAGCTGGATGATGCCCGGCGTAGGTTTCGCCGATCGATTCAGGCGATCGTGCTGGCCGCGCTTGGTCGCACA
ATTGCCCAAACGGTCGGTGATGGTGTGGTCGCCGTAGAGCTTGAGGGCGAGGGCCGTTCGGTGTTGCGGCCGGACGTCGA
CGTGCGCAGAACAATCGGTTGGTTCACGAACTATTACCCAATTCCGCTGGTCTGCGTGAAGGGCCAGGGCGCGCTTGCGC
AACTAGACGCTGTTCATAACACCCTTAAATCCATTCCGCATTACGGAATTGGATACGGATTGCTGCGGTATATGTACGCG
CCGACCGGACGTGTATTCAGTGCGCAGCGCACGCCTGACATTCACTTTCGGTACGTGGGCGTTGTCCCTGAGCCGCCATC
CGTCGATGCTACGGTACAGTTCGACTCGGACATGACGATTCCGGTGCAAGAACCGGTTCCTGGGATGGGCCACGCCATCG
AACTTCGGACGTATCGGTTTGGTGGTTCACTGCATCTAGATTGGTGGTACGACATCCGGCGGATTCCGCAGGTAACAGCA
GAAGCACTCGCGCAGTCCTTCCCGGTCACGCTTAGCAAGTTGATCCAGGAAGGCATAGCTACGCAAAAGGATGCGCACGA
CGAGAGTGAAATGGCTGGGGCACCCCAAGCGGGCGTTCTGGTGGACCTGTCAACCCTGGATGCCGGCTGA

Upstream 100 bases:

>100_bases
TGACACCGTTCGCGACCGCGTTCAGCAGCGTGCGGCGGTGCGACGTGGAGCCGTGATGCGGCGCCGACCTAAACCTGACG
TACAGGGAGGATAGAAACCA

Downstream 100 bases:

>100_bases
GGAGGATCGGATGCGCAACAACGACAAGGCCGTGATGGTTCGCGGGGTTCGTAAGACCTACGGCAAGGGCAAGATTATCG
CCCTGGATGATGTTAGTTTC

Product: polyketide synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase I; DEBS 1; ORF 1 [H]

Number of amino acids: Translated: 1489; Mature: 1489

Protein sequence:

>1489_residues
MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLLDGIDEFDADFFGL
PPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDK
DFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDV
RADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETH
GTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQ
TPFVVQSNYGPWKWDGVRRAGVSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPG
APDLSDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHV
GMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNGTAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYS
TGEYIAATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQIR
AFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISSTIRF
ADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVM
PHLVSLPGYPFARQRHWVEPRYTIWAQIPGASSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFF
DLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRW
RVPLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILA
ELIASQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAA
LATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDARRRFRRSIQAIVLAALGRT
IAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIPLVCVKGQGALAQLDAVHNTLKSIPHYGIGYGLLRYMYA
PTGRVFSAQRTPDIHFRYVGVVPEPPSVDATVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTA
EALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG

Sequences:

>Translated_1489_residues
MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLLDGIDEFDADFFGL
PPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDK
DFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDV
RADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETH
GTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQ
TPFVVQSNYGPWKWDGVRRAGVSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPG
APDLSDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHV
GMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNGTAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYS
TGEYIAATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQIR
AFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISSTIRF
ADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVM
PHLVSLPGYPFARQRHWVEPRYTIWAQIPGASSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFF
DLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRW
RVPLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILA
ELIASQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAA
LATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDARRRFRRSIQAIVLAALGRT
IAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIPLVCVKGQGALAQLDAVHNTLKSIPHYGIGYGLLRYMYA
PTGRVFSAQRTPDIHFRYVGVVPEPPSVDATVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTA
EALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG
>Mature_1489_residues
MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLLDGIDEFDADFFGL
PPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDK
DFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDV
RADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETH
GTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQ
TPFVVQSNYGPWKWDGVRRAGVSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPG
APDLSDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHV
GMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNGTAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYS
TGEYIAATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQIR
AFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISSTIRF
ADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVM
PHLVSLPGYPFARQRHWVEPRYTIWAQIPGASSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFF
DLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRW
RVPLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILA
ELIASQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAA
LATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDARRRFRRSIQAIVLAALGRT
IAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIPLVCVKGQGALAQLDAVHNTLKSIPHYGIGYGLLRYMYA
PTGRVFSAQRTPDIHFRYVGVVPEPPSVDATVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTA
EALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=892, Percent_Identity=26.9058295964126, Blast_Score=255, Evalue=3e-67,
Organism=Homo sapiens, GI8923559, Length=282, Percent_Identity=29.4326241134752, Blast_Score=107, Evalue=1e-22,
Organism=Homo sapiens, GI51243059, Length=329, Percent_Identity=25.2279635258359, Blast_Score=74, Evalue=1e-12,
Organism=Escherichia coli, GI1787337, Length=283, Percent_Identity=30.3886925795053, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1787334, Length=297, Percent_Identity=28.956228956229, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI1788663, Length=281, Percent_Identity=23.1316725978648, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17550940, Length=908, Percent_Identity=26.5418502202643, Blast_Score=278, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI212642053, Length=898, Percent_Identity=27.5055679287305, Blast_Score=261, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=288, Percent_Identity=28.125, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983535, Length=279, Percent_Identity=28.673835125448, Blast_Score=80, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320904, Length=280, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581345, Length=907, Percent_Identity=28.0044101433297, Blast_Score=252, Evalue=2e-66,
Organism=Drosophila melanogaster, GI221330659, Length=907, Percent_Identity=27.2326350606395, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI19920632, Length=909, Percent_Identity=27.3927392739274, Blast_Score=247, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24644341, Length=279, Percent_Identity=30.1075268817204, Blast_Score=87, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 159762; Mature: 159762

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAY
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHEEECCHHHHHHCCCCCHHHCCHHH
VRRAPLLDGIDEFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVY
HHHCCCCCCHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEE
GTSSPSGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAV
ECCCCCHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEE
QTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDV
EHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCEECCHHHHHHHHCCCCCCC
RADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVI
CCCCEEEECCEEEEEECHHHHHHCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCHHHHH
AEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIG
HHHHHHCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEHHHCCCC
HLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDGVRRA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCEEEECCCCCCCCCCHHHC
GVSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPG
CCCCCCCCCCEEEEEEECCCCCHHHEEECCCCCEEEEECHHHHHHCCHHHHHHHHHHCCC
APDLSDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASI
CCCHHHHHHHHHCCCCCCEEEEEEECCCHHHEEHEEECCCCCEEEECCCCCCCCHHHHEE
TTLGSDRVVFLFPGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG
EECCCCCEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDLETAIK
CEEEHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
TVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQIR
HHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHHHH
AFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMS
HHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
EQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCCCCCHHH
VRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVMPHLVSLPGYPFARQRHWVEP
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHCCCCCCCHHCCCCCCC
RYTIWAQIPGASSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFF
CEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEE
DLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHP
ECCCCCEEEEEEEEEECCCCCEECCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
AVPPNIAYFLERGLCDTGRWRVPLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDG
CCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCC
MWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITT
CHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHCCCCCCEEEEEEE
AHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHCEEEEE
LATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDD
EECCCCCCCCHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCEEECCEEEEHHHHHHHHH
ARRRFRRSIQAIVLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCC
IPLVCVKGQGALAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPDIHFRYVG
CEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCEEEEEEE
VVPEPPSVDATVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTA
ECCCCCCCCEEEEECCCCEEECCCCCCCCCCEEEEEEEEECCEEEEEEHHHHHHHHHHHH
EALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG
HHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAY
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHEEECCHHHHHHCCCCCHHHCCHHH
VRRAPLLDGIDEFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVY
HHHCCCCCCHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEE
GTSSPSGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAV
ECCCCCHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEE
QTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDV
EHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCEECCHHHHHHHHCCCCCCC
RADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVI
CCCCEEEECCEEEEEECHHHHHHCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCHHHHH
AEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIG
HHHHHHCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEHHHCCCC
HLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDGVRRA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCEEEECCCCCCCCCCHHHC
GVSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPG
CCCCCCCCCCEEEEEEECCCCCHHHEEECCCCCEEEEECHHHHHHCCHHHHHHHHHHCCC
APDLSDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASI
CCCHHHHHHHHHCCCCCCEEEEEEECCCHHHEEHEEECCCCCEEEECCCCCCCCHHHHEE
TTLGSDRVVFLFPGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG
EECCCCCEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDLETAIK
CEEEHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
TVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQIR
HHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHHHH
AFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMS
HHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
EQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCCCCCHHH
VRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVMPHLVSLPGYPFARQRHWVEP
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHCCCCCCCHHCCCCCCC
RYTIWAQIPGASSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFF
CEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEE
DLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHP
ECCCCCEEEEEEEEEECCCCCEECCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
AVPPNIAYFLERGLCDTGRWRVPLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDG
CCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCC
MWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITT
CHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHCCCCCCEEEEEEE
AHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHCEEEEE
LATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDD
EECCCCCCCCHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCEEECCEEEEHHHHHHHHH
ARRRFRRSIQAIVLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCC
IPLVCVKGQGALAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPDIHFRYVG
CEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCEEEEEEE
VVPEPPSVDATVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTA
ECCCCCCCCEEEEECCCCEEECCCCCCCCCCEEEEEEEEECCEEEEEEHHHHHHHHHHHH
EALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG
HHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 8386127 [H]