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The map label for this gene is ptrB [H]

Identifier: 221230669

GI number: 221230669

Start: 2642785

End: 2644959

Strand: Reverse

Name: ptrB [H]

Synonym: MLBr_02226

Alternate gene names: 221230669

Gene position: 2644959-2642785 (Counterclockwise)

Preceding gene: 221230670

Following gene: 221230668

Centisome position: 80.93

GC content: 55.68

Gene sequence:

>2175_bases
ATGACAAAGACATCCAGGGGTACACCCGTACCGCCCATCGCCAAGCGCGTGGAGACTCGCAGGGAGCGCCACGGAGACGT
CTTTTTTGATCCGTATGAATGGTTGCGCGACAATAACAATCCCGAAGTTGTTGCTTATCTCGATGCTGAAAACGATTACG
TCAACCAGATGACTGCCCACCTTGAGCCGTTGCAGCAGAAGATTTTCAATGAGATCAAGGCGCGTACTAAGGAAAACGAC
CTGTCGGTGCCGACTCGCCAAGCCAACTGGTGGTACTATTCCCGCACCTTCGAGGGTAAGCAATATCGCGTCCAGTGTCG
TTGTCCGGTAGCAAGTCCCGATGACTGGACTCCGCCGGCCCTATACGAGAACACTGAAATATCCGGTGAGCAGGTTTTGC
TCGATTCGAATGCTGAGGCGGAGGGCCATGCCTTTTTTGCACTGGGTACCTTCATGGTCAGTTTGGATTCCAATCTGCTA
GCTTATTCTGTGGACTTCGTCGGTGACGAGCGGTATACGCTGCGGTTCAAGGACTTACGTACCGGAGAACGATACCCTGA
CGAGATTGTGGGTATCGGCGCCGGAGCGACCTGGGCTGCTGACAACCGCACCGTGTACTATCTGACTTTGGATGAGTCCC
GGCGTCCGGATACAGTGTGGCGGTGTCGGCTCGGCTCCGGTCAGCCGTCGGAGCAAGTTTATCATGAAGCTGATGAACGG
TTCTGGCTCGCGGTCGGCCTTAGCCGAAGTGAAGCTTACATATTTATAGCCGCCGGGTCGGCCATCACCTCCGAGTGGCG
CTACGCGGACTCGACTAACCCGGATGCGCAGTTCACCGTCGTGTTACCACGGCGTGACGGCATCGAGTACTCGGTAGAAC
ATGCCCCCAGCGGCCTAGTCGGGGGACAAGACCGGTTCTTGATTTTACACAATGACGGTGCGGTGAACTTCACACTGGTG
GAGTCACCGGTTAGCAATCCAGAACAGCAGCGCACCCTGATTCCACATCGCGACGACGTTCGACTGGACAGTGCTGATGC
CTTCGCTGGCTATCTGGTGGTCAGCTATCGACGTGAGGCGTTGCCCCGGGTTCAGTTGTGGCCTATCGACCCCGACGGGA
GCTACGGAGAGCCGGAAGAGATCTCGTTCGAGTCTGAACTGATGTGGGTCAGCCTGGAAGCCAATTCGAACTGGGTTTCG
CCCAAACTGCGGATCCGGGCAGGATCGTTTGTCACCCCGGTCCGTGTCTATGACGTGGATTTGGCTACCGGTGAGCGGAC
GTTGCTACGCGAGCAGCCCGTTCTCGGCGGCTACAAGCATGAGGACTATGTTGAACGGCGTGAATGGGCGCAGGCGGATG
ACGGCACCTGGATCCCAGTGTCGATCGTTCATCGCGCCGCTATCCGATTTCCTGCTCCGGCAGTGCTTTACGGCTATGGT
GCATACGAGATTTGTGTGGATCCGAGTTTTTCCATACCGCGGCTGTCGCTGCTGGACCGGGGAATGATGTTTGTCATTGC
TCACGTTCGGGGCGGTGGTGAAATGGGACGGCTGTGGTACGAGCATGGCAAGCTCTTGGAGAAGAAGAACACGTTTACTG
ACTTCATTTCGGTGGCAAAGCATTTGGTGGATTCAGGGCAGACACGATCACAAGAATTAGTAGCATTGGGCGGTAGCGCG
GGAGGCCTGTTGATGGGAGTGGTAGCTAACATAGCACCGGATCTCTTCACCGGAATCCTCGCTCAGGTGCCGTTTGTTGA
TCCGCTGACCACTATGCTGGATCCCTCGTTACCTCTGACCGTAACGGAGTGGGATGAATGGGGAAATCCGTTGATTGACA
GTGATTTTTACTCATATATTAAGTCTTATTCTCCCTATGAGAACGTCGAAGCCAAACAATATCCTGCCATCTTGGCTATG
ACATCACTGCACGATACCAGGGTCCACTATGTAGAGCCGGCGAAGTGGATTGCAGCACTGCGGCACACAAAGAGTGACGG
GAATCCAGTGTTGTTGAAAACCCAGATGGCCGCGGGCCATGCTGGCATAAGCGGACGCTACAAGGCTTGGCAGGAAACCG
CGTTCCAATATGCTTGGCTGCTAGCTGCTGTCGACGTCGATCAGTATGGCACCGCCACCGAGGTAGATGACCTCGGTGGC
GGTGCGCAGGGGTAG

Upstream 100 bases:

>100_bases
CGCTACCGGATGACATTATCGAGGCCACCCGTCTATGCTATGTCGAAGTTTATGAACGGATTTCCGGTATGAGCTTCGAC
GATTGGATCGGTCCAGGAGC

Downstream 100 bases:

>100_bases
CCGCGTCGTCATCGAATTAGGCGGATGGGGCATTTGCGCGGCGTAAACGTTGACTGGGAACATAGCCAGCATCAACGCCA
GCAAGCACACTGCGGCTGCT

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MTKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAHLEPLQQKIFNEIKARTKEND
LSVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLL
AYSVDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADER
FWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSGLVGGQDRFLILHNDGAVNFTLV
ESPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVS
PKLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYG
AYEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSA
GGLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAM
TSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGG
GAQG

Sequences:

>Translated_724_residues
MTKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAHLEPLQQKIFNEIKARTKEND
LSVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLL
AYSVDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADER
FWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSGLVGGQDRFLILHNDGAVNFTLV
ESPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVS
PKLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYG
AYEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSA
GGLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAM
TSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGG
GAQG
>Mature_723_residues
TKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAHLEPLQQKIFNEIKARTKENDL
SVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLLA
YSVDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADERF
WLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSGLVGGQDRFLILHNDGAVNFTLVE
SPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVSP
KLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYGA
YEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAG
GLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAMT
SLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGG
AQG

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=747, Percent_Identity=24.8995983935743, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI284172438, Length=527, Percent_Identity=26.5654648956357, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI284172431, Length=527, Percent_Identity=26.5654648956357, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI284172420, Length=527, Percent_Identity=26.5654648956357, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI284172413, Length=527, Percent_Identity=26.5654648956357, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI70778815, Length=527, Percent_Identity=26.5654648956357, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI108860686, Length=344, Percent_Identity=30.5232558139535, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI108860692, Length=260, Percent_Identity=32.6923076923077, Blast_Score=125, Evalue=1e-28,
Organism=Escherichia coli, GI1788150, Length=700, Percent_Identity=37.8571428571429, Blast_Score=448, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24583414, Length=743, Percent_Identity=25.7065948855989, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI221510989, Length=711, Percent_Identity=25.5977496483826, Blast_Score=160, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 81363; Mature: 81232

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAH
CCCCCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHCCCCCCCEEEEEECCCCHHHHHHHH
LEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCC
LYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLR
CCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEEECCCEEEEEEEEECCCEEEEEEEECC
TGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADER
CCCCCCCCEEEECCCCEEECCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHCCCE
FWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSGLV
EEEEEECCCCCEEEEEEECCEECCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCC
GGQDRFLILHNDGAVNFTLVESPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREA
CCCCCEEEEECCCEEEEEEEECCCCCCHHHCCCCCCCCCCEECCCCHHHHHEEEEEHHHH
LPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVD
CCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCEECEEEEEEEE
LATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYG
ECCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCEEEEECC
AYEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAK
EEEEEECCCCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHHCHHHHCCCHHHHHHHHHH
HLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLT
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEE
VTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAMTSLHDTRVHYVEPAKWIAAL
EECHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHCCEEEEEECCCCCEEEEECHHHHHHHH
RHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGG
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHEEEHEEECHHHCCCCCCHHHCCC
GAQG
CCCC
>Mature Secondary Structure 
TKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAH
CCCCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHCCCCCCCEEEEEECCCCHHHHHHHH
LEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCC
LYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLR
CCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEEECCCEEEEEEEEECCCEEEEEEEECC
TGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADER
CCCCCCCCEEEECCCCEEECCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHCCCE
FWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSGLV
EEEEEECCCCCEEEEEEECCEECCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCC
GGQDRFLILHNDGAVNFTLVESPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREA
CCCCCEEEEECCCEEEEEEEECCCCCCHHHCCCCCCCCCCEECCCCHHHHHEEEEEHHHH
LPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVD
CCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCEECEEEEEEEE
LATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYG
ECCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCEEEEECC
AYEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAK
EEEEEECCCCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHHCHHHHCCCHHHHHHHHHH
HLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLT
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEE
VTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAMTSLHDTRVHYVEPAKWIAAL
EECHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHCCEEEEEECCCCCEEEEECHHHHHHHH
RHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGG
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHEEEHEEECHHHCCCCCCHHHCCC
GAQG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]