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The map label for this gene is fprB

Identifier: 221230621

GI number: 221230621

Start: 2535738

End: 2537405

Strand: Reverse

Name: fprB

Synonym: MLBr_02134

Alternate gene names: 221230621

Gene position: 2537405-2535738 (Counterclockwise)

Preceding gene: 221230622

Following gene: 221230620

Centisome position: 77.64

GC content: 60.85

Gene sequence:

>1668_bases
ATGCCGTATATCATCACCCAGTCGTGCTGCAACGATGGGTCTTGTGTGTTTGCTTGCCCGGTGAATTGCATTCACCCAAC
ACCGGACGAGCCGGGGTTCGCTACTTCGGAGATGCTTTATATCGATCCTGTAGCCTGTGTGGATTGTGGCGCCTGTGTGA
GCGCCTGTCCGGTTGGTGCTATTGCATCCGACACCCGGTTGGCGCCTAAGCAGCTGCCGTTTATCGAGATCAACGCGTCG
TATTACCCGGCGCGGCCCATTGACCTGAAACTTCCGCCGACCTCGAAGTTGGCTCCGGTCATCCCGGCCGCACAGGTACA
TGTTCGTCGTCGCCCGCTGACCGTGGCCATCGTCGGGTCCGGTCCAGCGGCAATGTATGCTGCCGATGAGCTGCTTACTC
AACCTGGGGTGTGGGTTAATGTGTTCGAGAAGTTACCTACCCCTTACGGTTTGGTTCGCGCCGGGTTGGCGCCCGATCAC
CAGAACACGAAAAAGGTGACTGAGCTCTTCGACCGGGTCGCCGAGCATCGCCGCTTCCGTTTTTTTCTCAACGTCGAGAT
AGGTAGGCACTTGAGCCACGACGAATTGTTGGCCCATCACCATGCTGTGCTGTATGCGGTCGGTGCGCCTGATGATCGTC
GTCTGAACATCGACGGGATGGGTATCCCGGGTACTGGAACCGCTACCGAGCTAGTAGCCTGGATCAACGCTCATCCCGAC
TTTGCTTATCTACCAGTCGATCTCAGTCATGAACGCGTAGTAGTCATCGGTAATGGCAATGTCGCCCTCGATGTGGCACG
GTTGCTCACTGCCGATCCGGACAACTTGGCCCGGACCGATATTTCCGAGTTTGCACTGCACGTGTTGGGCGGCTCCGCGG
TCCGCGAAGTGGTGGTCGCCGCCCGTCGTGGCCCCGCGCACTCGGCGTTCACCTTGCCCGAGCTGATCGGGTTGAAGGCC
ACGTCTGAGGTGGTACTCGACGCCGGTGACCGCAAGTTGGTGGAAGGTGATTTCGCGACCGTATCAGACAGTTTGACCAG
AAAGAAACTGGAGGTCTTGAGCAGTCTTGTTGATAGTTCGAAGCCGACTTCGCGGCGGCGAATCCGGCTGGCCTATCAGC
TCACGCCCAAGCGCGTGCTTGGTAACCAGCGCGCTACCGGTGTTGAGTTCTCGGTTACCGGCACCGAAGAATCACGTCGG
TTCGATGCGGGCCTGGTGCTGACATCGGTTGGTTACCGCGGCAAACGGATTCGCGATCTGCCATTCGACGAGGAAGCGGC
GGTAATCCCGAATGACGGTGGCCGTGTGGTCGACCCGAGTCGGGGCCGTCCGATGCCCGGCGCCTATGTGGCTGGCTGGA
TCAAACGTGGACCAACAGGCTTCATCGGCACTAACAAGTTGTGCTCGGTTCAAACCGTTCAGGCCGTGGTCGCCGACTTC
AACGCCGGCTGGCTGACCGACCCGGTGGCTGAGCCGGCGGAGCTAGCCAAGCTGGTGCACGCCCGCCAACCCGATACTGT
CGACTCCGTGGGATGGCGGGCCATCGACGCCGCCGAGATCGCGCAGGGCAGTACCGAAGGCCGGCCACGCCGCAAGTTCA
CCGATGTCGCCGACATGCTGGCGGTTGCAGCCGGCGCGCCGCCGCTGCGGCTGCGTGCCCTGTCGTAG

Upstream 100 bases:

>100_bases
GCATATATGCAAGATCGATGGGCAGCCGTCGCGTTATCGTGGTGAGCCGCAGCGTCAGCACCCGGCGACGACATCTGCCG
CTTAAGCTTTACGAGTTTCT

Downstream 100 bases:

>100_bases
TCAGCTCGAACTAACTGCCTATCTGCCCAGAGATCGCCGCTCCGATCTCATCTATGCTGGCCTTGCGGACTGGCTGTCCC
GGGGGCCAGCGTTGGACCGA

Product: ferredoxin, ferredoxin-NADP reductase

Products: NA

Alternate protein names: FNR

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVSACPVGAIASDTRLAPKQLPFIEINAS
YYPARPIDLKLPPTSKLAPVIPAAQVHVRRRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDH
QNTKKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPD
FAYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVVAARRGPAHSAFTLPELIGLKA
TSEVVLDAGDRKLVEGDFATVSDSLTRKKLEVLSSLVDSSKPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESRR
FDAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADF
NAGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADMLAVAAGAPPLRLRALS

Sequences:

>Translated_555_residues
MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVSACPVGAIASDTRLAPKQLPFIEINAS
YYPARPIDLKLPPTSKLAPVIPAAQVHVRRRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDH
QNTKKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPD
FAYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVVAARRGPAHSAFTLPELIGLKA
TSEVVLDAGDRKLVEGDFATVSDSLTRKKLEVLSSLVDSSKPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESRR
FDAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADF
NAGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADMLAVAAGAPPLRLRALS
>Mature_554_residues
PYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVSACPVGAIASDTRLAPKQLPFIEINASY
YPARPIDLKLPPTSKLAPVIPAAQVHVRRRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDHQ
NTKKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPDF
AYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVVAARRGPAHSAFTLPELIGLKAT
SEVVLDAGDRKLVEGDFATVSDSLTRKKLEVLSSLVDSSKPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESRRF
DAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADFN
AGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADMLAVAAGAPPLRLRALS

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI111118981, Length=458, Percent_Identity=38.2096069868996, Blast_Score=265, Evalue=6e-71,
Organism=Homo sapiens, GI111118983, Length=464, Percent_Identity=37.7155172413793, Blast_Score=259, Evalue=4e-69,
Organism=Escherichia coli, GI87082180, Length=168, Percent_Identity=29.7619047619048, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789606, Length=165, Percent_Identity=31.5151515151515, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788811, Length=171, Percent_Identity=30.4093567251462, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=458, Percent_Identity=32.7510917030568, Blast_Score=207, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17570289, Length=171, Percent_Identity=30.4093567251462, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320584, Length=487, Percent_Identity=29.3634496919918, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6320030, Length=264, Percent_Identity=26.5151515151515, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137178, Length=448, Percent_Identity=34.8214285714286, Blast_Score=230, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FPRB_MYCLE (O33064)

Other databases:

- EMBL:   Z99494
- EMBL:   AL583924
- PIR:   T45351
- RefSeq:   NP_302407.1
- ProteinModelPortal:   O33064
- EnsemblBacteria:   EBMYCT00000029433
- GeneID:   909093
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2134
- NMPDR:   fig|272631.1.peg.1279
- Leproma:   ML2134
- GeneTree:   EBGT00050000014581
- HOGENOM:   HBG522200
- OMA:   AWINGHP
- ProtClustDB:   CLSK790809
- BioCyc:   MLEP272631:ML2134-MONOMER
- BRENDA:   1.18.1.2
- GO:   GO:0006810
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000362

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 59713; Mature: 59582

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: BINDING 123-123 BINDING 143-143 BINDING 151-151 BINDING 187-187 BINDING 213-213 BINDING 314-314 BINDING 453-453 BINDING 460-460

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVSACPVGA
CCEEEEHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCC
IASDTRLAPKQLPFIEINASYYPARPIDLKLPPTSKLAPVIPAAQVHVRRRPLTVAIVGS
CCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCCHHHEEECCCEEEEEECC
GPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDHQNTKKVTELFDRVAEHRRFR
CCHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEE
FFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPD
EEEEEEECCCCCHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCC
FAYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVVA
EEEEEEECCCCEEEEEECCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
ARRGPAHSAFTLPELIGLKATSEVVLDAGDRKLVEGDFATVSDSLTRKKLEVLSSLVDSS
HCCCCCCCCCCCHHHHCCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCC
KPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESRRFDAGLVLTSVGYRGKRIRDL
CCCCCEEEEEEEEECHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCEECCC
PFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADF
CCCCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
NAGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADML
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCEEECHHHHHCCCCCCCCCHHHHHHHHHH
AVAAGAPPLRLRALS
HHHCCCCCCEEEECC
>Mature Secondary Structure 
PYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVSACPVGA
CEEEEHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCC
IASDTRLAPKQLPFIEINASYYPARPIDLKLPPTSKLAPVIPAAQVHVRRRPLTVAIVGS
CCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCCHHHEEECCCEEEEEECC
GPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDHQNTKKVTELFDRVAEHRRFR
CCHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEE
FFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPD
EEEEEEECCCCCHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCC
FAYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVVA
EEEEEEECCCCEEEEEECCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
ARRGPAHSAFTLPELIGLKATSEVVLDAGDRKLVEGDFATVSDSLTRKKLEVLSSLVDSS
HCCCCCCCCCCCHHHHCCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCC
KPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESRRFDAGLVLTSVGYRGKRIRDL
CCCCCEEEEEEEEECHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCEECCC
PFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADF
CCCCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
NAGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADML
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCEEECHHHHHCCCCCCCCCHHHHHHHHHH
AVAAGAPPLRLRALS
HHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002