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The map label for this gene is tauD [C]

Identifier: 221230557

GI number: 221230557

Start: 2379974

End: 2380843

Strand: Direct

Name: tauD [C]

Synonym: MLBr_01992

Alternate gene names: 221230557

Gene position: 2379974-2380843 (Clockwise)

Preceding gene: 221230556

Following gene: 221230558

Centisome position: 72.83

GC content: 50.23

Gene sequence:

>870_bases
ATGACGCTCGATGTGAAAGGTGATGGACTTGGTGCACAGGTCACAGGGGTTGACCCCAAAAACTTAGACAGTATATCCAC
CGCCGAAATCCGCAAAATAGTTTATGTCAATAAGCTTGTTGTTTTAAAAGACGTCCACCCAACTCCAGAAGAATTTATAA
AACTTGGCAGGATAATCGGAGAAATCGTTCCTTATTACGAACCTATTTATCGCCATAAAGATTATCCTGAAATATTTGTT
TCTTCTACCGAGGAAGGGCAGGGTGTTCCGAACACCGGCGCCTTCTGGCATGTCGACTATATATTCATGCCGGAACCTTT
TGCATTTTCTATGACTCTGCCTCTTGCGATGCCCGGACACGACCGCGGGACTCATTTTATCGACCTCAGCCAGGTTTGGG
AATCGCTTCCCAACGCTATGAAAGACTCGGTGCGGGGAACGTATAGTAATCATTCTCCTCGGCGCTATATCAAAATACGC
CCAAGCGATGTTTACCGACCTGTAGGAGAAGTCCTAGCCGAGATCGAAGAGGTCACTCCCCCGCAGAAGTGGCCTACAGT
GATCAAGCACCCGAAGACCGGGCAGGAAATCCTTTACATTTGCGAAGCAGCCACCGTTTCGGTCGAGGACAAAAACGGAA
ATCTACTTGACCCGATGGTGCTGCAAGAGCTCCTAACCGCGTCGGGCCAGCTTGACCCCGACTGCAAATCGCTGCTTATA
CATACTCAACACTACGAGGTTGGTGACGTCGTCTTGTGGGATAACCGGGCTCTTGTGCACCGGGCGAAACACGGCACGGT
CTCGGGCACCTTAATCACGTACCGTCTGACCTTGCTGGATGGCCTCAAGACACCGGGATATGCCGTATGA

Upstream 100 bases:

>100_bases
ATGCAACCGATTTTTCATCAAGGAGGTATGGATCGTGACGGCGAGAGATGCTCAAAGATGTGGACCAAAAACAGTAAGTA
AATGAGGAGAAAAAGAATCA

Downstream 100 bases:

>100_bases
GCGCCGAGTTGGCCCCTTCTCTGCAGAACGCGGCGGAATCCACAAACACCTTTCCTATGGCAGAAGATTTGCTTGGCAGC
ATACTGGAACCCTACTCTTA

Product: putative oxidoreductase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDVHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFV
SSTEEGQGVPNTGAFWHVDYIFMPEPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRGTYSNHSPRRYIKIR
PSDVYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLI
HTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV

Sequences:

>Translated_289_residues
MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDVHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFV
SSTEEGQGVPNTGAFWHVDYIFMPEPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRGTYSNHSPRRYIKIR
PSDVYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLI
HTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV
>Mature_288_residues
TLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDVHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVS
STEEGQGVPNTGAFWHVDYIFMPEPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRGTYSNHSPRRYIKIRP
SDVYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLIH
TQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=281, Percent_Identity=24.1992882562278, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 32372; Mature: 32241

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDVHPTPEEFIKLGRIIG
CEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHH
EIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGAFWHVDYIFMPEPFAFSMTLPLAMPGH
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCC
DRGTHFIDLSQVWESLPNAMKDSVRGTYSNHSPRRYIKIRPSDVYRPVGEVLAEIEEVTP
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC
PQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLI
CCCCCHHHCCCCCCCEEEEEEEEEEEEEECCCCCEECHHHHHHHHHHCCCCCCCHHHHEE
HTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV
EECCCCCCCEEEECCCCEEECCCCCCCCCEEEEEEEEHHHCCCCCCCCC
>Mature Secondary Structure 
TLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDVHPTPEEFIKLGRIIG
EEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHH
EIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGAFWHVDYIFMPEPFAFSMTLPLAMPGH
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCC
DRGTHFIDLSQVWESLPNAMKDSVRGTYSNHSPRRYIKIRPSDVYRPVGEVLAEIEEVTP
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC
PQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLI
CCCCCHHHCCCCCCCEEEEEEEEEEEEEECCCCCEECHHHHHHHHHHCCCCCCCHHHHEE
HTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV
EECCCCCCCEEEECCCCEEECCCCCCCCCEEEEEEEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]