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The map label for this gene is coaA [H]

Identifier: 221230533

GI number: 221230533

Start: 2341488

End: 2342426

Strand: Direct

Name: coaA [H]

Synonym: MLBr_01954

Alternate gene names: 221230533

Gene position: 2341488-2342426 (Clockwise)

Preceding gene: 221230527

Following gene: 221230542

Centisome position: 71.65

GC content: 59.53

Gene sequence:

>939_bases
ATGCCACGGCTTAGCGAGCCGAGCCCGTATGTCGAGTTTGACCGAAAGCAGTGGCGCGCGCTTCGCATGTCGACGCCACT
AGCCCTCACCGAAGAGGAACTGATCGGCTTACGTGGTCTTGGTGAACAGATCGACCTGCTCGAAGTTGAAGAGGTTTACC
TACCACTAGCCCGGCTGATTCATCTTCAGGTAGCCGCCCGCCAGCGCTTGTTTGCCGCCACCGCGGAATTCCTCGGCGAG
CCACAACAAAACCCTGGCCGGCCGGTGCCGTTCATCATCGGGGTGGCTGGCAGCGTGGCAGTCGGCAAATCAACCACCGC
CCGCGTGCTGCAAGCACTGTTGGCTCGCTGGGATCACCATACCCGGGTCGATCTGGTGACCACCGACGGTTTTCTCTATC
CCAACGCCGAATTGGGTAGGCGCAATCTTATGCACCGCAAAGGTTTTCCAGAAAGTTATAACCGCCGGGCACTGATGCGG
TTCGTGACCTCGGTGAAGTCCGGTGCCGATTACGCGTGCGCACCAGTGTATTCACATCTGCGCTACGACACCATCCCCGG
TGCCAAGCACGTGGTCCGCCATCCCGATATCCTGATCTTGGAGGGTCTCAACGTATTGCAGACCGGCCCCACCCTGATGG
TGTCTGACTTATTCGACTTCTCGCTCTACGTGGACGCCCGGATCCAAGACATCGAGCAGTGGTACGTGTCGCGGTTTTTG
GCCATGCGCGGTACGGCATTCGCCGACCCAGAGTCACACTTCCACCACTACTCGGCTCTGACCGATTCGAAGGCAATCAT
CGCCGCCCGAGAAATCTGGCGGTCGATCAACCGGCCCAACCTGGTAGAGAACATTCTGCCGACCCGCCCCCGCGCCACCC
TGGTACTACGCAAAGACGCTGACCACTCCATTAACCGGCTACGCTTGCGCAAGCTGTAG

Upstream 100 bases:

>100_bases
CGAGCATCAGATGCGGCAGTCACAGCCGCCAGTCTATCGCGTGTTAGCTTTTAGCCAGCCCAGCCGTCGTGCGCACGCCT
TATCCTGCAAGACTGGCACT

Downstream 100 bases:

>100_bases
CGCAAGAACAAACTGAGGCGGGTCAGCGGCTCGAGTTGGTTAATCACCTCATATTTAGCGACCGGCCAGTGCAACCTCCG
TTGTCCCGCCCGGCCAGTAA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGE
PQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMR
FVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFL
AMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL

Sequences:

>Translated_312_residues
MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGE
PQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMR
FVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFL
AMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
>Mature_311_residues
PRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEP
QQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRF
VTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFLA
MRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=52.7331189710611, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35492; Mature: 35361

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLI
CCCCCCCCCCCHHCHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCC
TRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRFVTSVKSGADYACAPVYSHL
CEEEEEEECCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFL
HCCCCCCCHHHHCCCCEEEECCCHHHHCCCCEEEHHHHHHEEEEHHHHHHHHHHHHHHHH
AMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDA
HHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEECCC
DHSINRLRLRKL
CCCHHHHHHCCC
>Mature Secondary Structure 
PRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLI
CCCCCCCCCCHHCHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCC
TRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRFVTSVKSGADYACAPVYSHL
CEEEEEEECCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFL
HCCCCCCCHHHHCCCCEEEECCCHHHHCCCCEEEHHHHHHEEEEHHHHHHHHHHHHHHHH
AMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDA
HHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEECCC
DHSINRLRLRKL
CCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]