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The map label for this gene is desA2 [H]

Identifier: 221230531

GI number: 221230531

Start: 2339195

End: 2340022

Strand: Reverse

Name: desA2 [H]

Synonym: MLBr_01952

Alternate gene names: 221230531

Gene position: 2340022-2339195 (Counterclockwise)

Preceding gene: 221230532

Following gene: 221230530

Centisome position: 71.6

GC content: 56.28

Gene sequence:

>828_bases
ATGGCACAGAAACCTGTACCTAACGCATTGATCCTTCAGCTTGAGCCTGTGGTGAAAGACAACATGGCTCGACACTTCGC
AAACGAGGAACTCTGGTTCGCCCACGACTACGTACCGTTCGACCGGGGTGAAAACTTTGCCTTCCTTGGCGGCCGCGATT
GGGATCCGTCCCAGGCGACGTTGGCCAAGGCCGTCACGGACGCCTGCGAGATCCTGCTGATTCTTAAAGACAACCTCGCC
GGTTATCACCGCGAACTCGTCGAGCATTTCATTCTCGAAGGTTGGTGGGGTCGTTGGCTCGGCAGGTGGACCGCGGAGGA
GCATCTGCATGCCATCGCATTGCGCGAATACTTGGTAGTGACCCGAGAAGTCGATCCGGTAGCCAACGAACAGGTTCGAG
TCGAGCACGTGATGAAGGGCTACCGCGTCAACTCGTACACGCAGATCGAAACCTTGGTCTACATGGCGTTCCTGGAGCGC
AGTTACGCCTTTTTCTGCGGCAGCTTGGCAGCGCAGATTAAGGAGCCCGCTTTGTTCGGACTGATCAACCAGATCGTCAA
AGACGAAGTACGTCACGAGGAGTTCTTCGCCAACCTCGTCGCGCACTGTCTGGAGTGCAATCGCGACGAGACGGTCGCCG
CGATTGCCGCTCGTGCAGCCGGTCTAGATGTCCTCGGTGCTGACATTGACGCTTACCACGACAAAGTAGAAAACATCTCC
GCTGCTGGTATTTTCGGATCTGTCGAACTGCGGCAAGTGATCTCCGACCGCATCACCGCATGGGGTTTGATAAACGAACC
GCAACTGGCGCAATTCGTCACCAGCTAA

Upstream 100 bases:

>100_bases
CGCTCTACGGGGGACTTGAGGACTGGAGCTTGGCCGGTCGCTAGGTTACACGTAATCTTCTGATTTAACAAAAACTGTGT
AAACGGGTTACAGTTACCTT

Downstream 100 bases:

>100_bases
GTCGCTTTTCCTCCCGACGTACGCTGGGAATCCTCGCCAGTCCGGTCTCGGCGCGCCTGCGCAACGGCAGTGCCGCCACG
AGAGTAGCGTTGTATTCGAT

Product: acyl-[ACP] desaturase

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA2 [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MAQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGENFAFLGGRDWDPSQATLAKAVTDACEILLILKDNLA
GYHRELVEHFILEGWWGRWLGRWTAEEHLHAIALREYLVVTREVDPVANEQVRVEHVMKGYRVNSYTQIETLVYMAFLER
SYAFFCGSLAAQIKEPALFGLINQIVKDEVRHEEFFANLVAHCLECNRDETVAAIAARAAGLDVLGADIDAYHDKVENIS
AAGIFGSVELRQVISDRITAWGLINEPQLAQFVTS

Sequences:

>Translated_275_residues
MAQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGENFAFLGGRDWDPSQATLAKAVTDACEILLILKDNLA
GYHRELVEHFILEGWWGRWLGRWTAEEHLHAIALREYLVVTREVDPVANEQVRVEHVMKGYRVNSYTQIETLVYMAFLER
SYAFFCGSLAAQIKEPALFGLINQIVKDEVRHEEFFANLVAHCLECNRDETVAAIAARAAGLDVLGADIDAYHDKVENIS
AAGIFGSVELRQVISDRITAWGLINEPQLAQFVTS
>Mature_274_residues
AQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGENFAFLGGRDWDPSQATLAKAVTDACEILLILKDNLAG
YHRELVEHFILEGWWGRWLGRWTAEEHLHAIALREYLVVTREVDPVANEQVRVEHVMKGYRVNSYTQIETLVYMAFLERS
YAFFCGSLAAQIKEPALFGLINQIVKDEVRHEEFFANLVAHCLECNRDETVAAIAARAAGLDVLGADIDAYHDKVENISA
AGIFGSVELRQVISDRITAWGLINEPQLAQFVTS

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 31140; Mature: 31009

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGENFAFLGGRDWDPSQAT
CCCCCCCCEEEEEECHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCCHHHH
LAKAVTDACEILLILKDNLAGYHRELVEHFILEGWWGRWLGRWTAEEHLHAIALREYLVV
HHHHHHHHHHEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TREVDPVANEQVRVEHVMKGYRVNSYTQIETLVYMAFLERSYAFFCGSLAAQIKEPALFG
HCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LINQIVKDEVRHEEFFANLVAHCLECNRDETVAAIAARAAGLDVLGADIDAYHDKVENIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHHCCH
AAGIFGSVELRQVISDRITAWGLINEPQLAQFVTS
HHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCC
>Mature Secondary Structure 
AQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGENFAFLGGRDWDPSQAT
CCCCCCCEEEEEECHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCCHHHH
LAKAVTDACEILLILKDNLAGYHRELVEHFILEGWWGRWLGRWTAEEHLHAIALREYLVV
HHHHHHHHHHEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TREVDPVANEQVRVEHVMKGYRVNSYTQIETLVYMAFLERSYAFFCGSLAAQIKEPALFG
HCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LINQIVKDEVRHEEFFANLVAHCLECNRDETVAAIAARAAGLDVLGADIDAYHDKVENIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHHCCH
AAGIFGSVELRQVISDRITAWGLINEPQLAQFVTS
HHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]