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The map label for this gene is PPE [H]

Identifier: 221230453

GI number: 221230453

Start: 2212373

End: 2214091

Strand: Reverse

Name: PPE [H]

Synonym: MLBr_01828

Alternate gene names: 221230453

Gene position: 2214091-2212373 (Counterclockwise)

Preceding gene: 221230455

Following gene: 221230452

Centisome position: 67.75

GC content: 61.2

Gene sequence:

>1719_bases
GTGAGTGCGCCGATCTGGATGGCGTCACCCCCGGAGGTGCACTCGGCGCTGCTAAGCAGAGGCCCAGGATCCGGTCCACT
GCTAGTGGCAGCTGAAGCGTGGCGCTCGTTGAGTAGCGTGTACGCTGAGATGGCCGACGAGCTGGTCGCGCTGTTGGTGG
TGGTGCCGGTTAGCTCCTGGGACGGTTCGGCCGCCGAGGCATATGTGATCGCCTATTTGCCGTATTTAGGGTGGCTGAGG
CAAGCCAGCGTTGATAGCGCTGTGATGGCAGCCCACTATGAAACCATGGCCACAGCCTACATCACCACTTTGGCGATGAT
GCCGACGTTGGCTGAGCTAGCCGCCAACCGTACTGCCCACACGGTGTTGGTGACCACTAATTTCTTCGGCATCAACACTA
TCCCGATCGCTCGCAACGAAATCGACTACGTGCGGATGTGGGTCGAGGCCGCCATTGCGATGGGCACCTATCAGGAGGTC
TCTACGGTGGTGGTGGATTCCGCCCCGGAGGCCATCGCCGCCCCCCAGATCATGGCAAGCGACGCGCTGGAAGCCAGTTC
CGACCAGCCGTCGCCGACAGCCCCCAGCCAGTCCCCTCAGGTCCAAAATTGGTTGCAATGGTTGCAGAAGATCGGCTACA
CCGACTTTTACAACACTTTGGTTCAACCGCTAATAACCTCGTTGACGAACCACCCTTTCTTCCAAGGGATGTTTTCCGGA
TTTGATCCTTGGTTGCCTTCGCTTGGTAATCCGCTTAGTTTCCTCAGCCCTTTCAACATTGCGTTTGCCCTAGGCACTCC
GATGGACATAGGTTCATATGTCGGTTATTTGTCCCAGACCTTCGCTTTTATCGGGGCCGATCTTGCAGCGGCGTTCGCTT
CGGGTAATCCTGTGACTATCGGTTTCACCCTGCTGTTCACCACCATCGAAGCCATTGGCACGATTATCACCGATACCATC
GCGTTGGTTAAGACTATGATTGAACAGTCTTTTGTGCTGCTCCCGATGATTCTACCGCTGTTGACCGCTCCGTTAGCGGT
TGCCACCGCGGGTGCAGCGGGCAGTTTCGCGGGCTTGTCGGAGCTGGCGGGCCTGGTTGGTGTGGCACCACCCGGGTTGC
CGTCCGCTCCGCCCGTAGCAGCGGTGGCCCCGGTCGTCCCGCCTTCGATGCCCACCTTAGCTTCGATACCGACTCCGACC
CCGATGCCGGCTCCAGCAGCCTCGACCGCGCCGGTCGTCACGCCGCCTGGTCCGCCGCCGGTTACCGCACCACCGTCGGT
GACCGGTGCGGGCGTGGAAAGCTTCGGTTACCTGGTGGGTCGCCTGCCGTCGACGGCCAGGGGGGTGGTGGGCACTAGCG
TCCGACAGCAGTCATCAGCACCCGACCGCATCGAAGCCCCTGACGCTGCGGCAACGCCCCAGGAGCAAGCTCGATCGCGG
TGGCGTCGACGGGCAAAGGTCACACCGTTCGACTCGAGCGGTTCGCCCAACCCGAAGGCCGCGCCGACGGCATCGGATCA
AGGCGCAGGAACTCTGGGGTTAGCCGGAACTGCCCGCCAGGCCAGTTCCGGACCCGCCACAGGATTGGTCACTCTGTCCA
ACGGTACGTTCAGCGACAGTCCACGCGCGCCAATGTTGCCGCGAACCTGGGGTGCTGACCCAACTTTCTGTTACAATGCG
GCTGATATTGGTCCTGCTGGTGGCTGGGACGACGAATGA

Upstream 100 bases:

>100_bases
CGGAGAAAGCTGTCTTAGTCGTGACGTTGCAACTTTATACTTTTTCGGCCCGGTCGCCACTATGGAGCGTTGAATCGCAT
CCGATTACGGGTGGCTCGCG

Downstream 100 bases:

>100_bases
CTCTAGATAAGAGCGTCGTGACCGCGGGGCTATGCCGCGCGTTGGCTCGACGTGACGTACGGGTGAAGCATTTACTTTAA
AGCGTGGAACATGTCCGATA

Product: PPE-family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLR
QASVDSAVMAAHYETMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMGTYQEV
STVVVDSAPEAIAAPQIMASDALEASSDQPSPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSG
FDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVTIGFTLLFTTIEAIGTIITDTI
ALVKTMIEQSFVLLPMILPLLTAPLAVATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASIPTPT
PMPAPAASTAPVVTPPGPPPVTAPPSVTGAGVESFGYLVGRLPSTARGVVGTSVRQQSSAPDRIEAPDAAATPQEQARSR
WRRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNA
ADIGPAGGWDDE

Sequences:

>Translated_572_residues
MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLR
QASVDSAVMAAHYETMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMGTYQEV
STVVVDSAPEAIAAPQIMASDALEASSDQPSPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSG
FDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVTIGFTLLFTTIEAIGTIITDTI
ALVKTMIEQSFVLLPMILPLLTAPLAVATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASIPTPT
PMPAPAASTAPVVTPPGPPPVTAPPSVTGAGVESFGYLVGRLPSTARGVVGTSVRQQSSAPDRIEAPDAAATPQEQARSR
WRRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNA
ADIGPAGGWDDE
>Mature_571_residues
SAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQ
ASVDSAVMAAHYETMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMGTYQEVS
TVVVDSAPEAIAAPQIMASDALEASSDQPSPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSGF
DPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVTIGFTLLFTTIEAIGTIITDTIA
LVKTMIEQSFVLLPMILPLLTAPLAVATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASIPTPTP
MPAPAASTAPVVTPPGPPPVTAPPSVTGAGVESFGYLVGRLPSTARGVVGTSVRQQSSAPDRIEAPDAAATPQEQARSRW
RRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNAA
DIGPAGGWDDE

Specific function: Unknown

COG id: COG5651

COG function: function code N; PPE-repeat proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000030 [H]

Pfam domain/function: PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 59225; Mature: 59094

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVALLVVVPVSSW
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYETMATAYITTLAMMPTLAELAANRTAH
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
TVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMGTYQEVSTVVVDSAPEAIAAPQIMAS
EEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEECCCCHHHHCCHHHHH
DALEASSDQPSPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSG
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCC
FDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVTI
CCCHHHHCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
GFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPLLTAPLAVATAGAAGSFAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASIPTPTPMPAPAASTAPVVTPPGPPP
HHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCC
VTAPPSVTGAGVESFGYLVGRLPSTARGVVGTSVRQQSSAPDRIEAPDAAATPQEQARSR
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
WRRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFSDS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCC
PRAPMLPRTWGADPTFCYNAADIGPAGGWDDE
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVALLVVVPVSSW
CCCCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYETMATAYITTLAMMPTLAELAANRTAH
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
TVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMGTYQEVSTVVVDSAPEAIAAPQIMAS
EEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEECCCCHHHHCCHHHHH
DALEASSDQPSPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSG
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCC
FDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVTI
CCCHHHHCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
GFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPLLTAPLAVATAGAAGSFAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASIPTPTPMPAPAASTAPVVTPPGPPP
HHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCC
VTAPPSVTGAGVESFGYLVGRLPSTARGVVGTSVRQQSSAPDRIEAPDAAATPQEQARSR
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
WRRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFSDS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCC
PRAPMLPRTWGADPTFCYNAADIGPAGGWDDE
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]