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The map label for this gene is iap [H]

Identifier: 221230446

GI number: 221230446

Start: 2191773

End: 2192498

Strand: Reverse

Name: iap [H]

Synonym: MLBr_01811

Alternate gene names: 221230446

Gene position: 2192498-2191773 (Counterclockwise)

Preceding gene: 221230447

Following gene: 221230445

Centisome position: 67.09

GC content: 60.47

Gene sequence:

>726_bases
ATGCGCCACAAGAATTTTCGCCTGATCAATCTAGCCGGGCTCACCGCGATGGTGGCCGGGTTGATTATCGTTGTCACGAT
ACCTGCTACGGCAGACCCTGGCCAGTGGGATCCGACATTGCCAGCAGCGGTGAGTGCGGGGGCCCCGGGAGATCCGCTCG
CTGTTGCCAACGCTTCGCTGCAGGTCACCGCTCAAGCAACCCAGACCACGCTCGATCTGGGTAAGCAATTTCTGGGTAGG
CTAGGGATCAATTTCGGTGGCGATCCTTCCAACGCCGCGACCACATCCAGCAACCCGGGAGGCCGGATTCCGCGGGTCTA
CGGTGGTCAGGCCATCGAGTACGTGATCAAGCGGGGTGGGGCACAGATCGGGGTGCCGTATTCGTGGGGTGGCGGCTCGC
TGCAGGGTCCCAGCAAGGGGGTCGGCGATGGTGCCAACATTACCGGTTTCGACTGCTCGGGTCTGATGCGATATGCGTTC
GCTGGCGTTGGCGTGCTGATCCCGCGGTTTTCCGGTGATCAATACAATGCCGGTCGCCACCTTACTCCCGACCAGGCCAA
GCGCGGTGACCTGATTTTTTACGGCCCGGGTGGAGGTCAGCATGTCACCATGTATCTGGGCAACGGTCAGATGTTGGAAG
CATCTAGCAGCGTCGGCAAAGTCACCGTCAGCTCGGTGCGTAAGGCTGGTATGACGCCGTTTGTGACTCGGATCATCGAG
TCTTGA

Upstream 100 bases:

>100_bases
GCTTGAGGGTGCGTGTTGCACCTGTGCGCACCAGTGGCATGACTCCGTATGTGGTCCGCTACATCGAATACTAAACGAGG
CTGAATATCAACGAGGAGCT

Downstream 100 bases:

>100_bases
TTCGGTGCGTTGTCAAGCTGGTGGTCCGGGCCGGCACGGTTTGCACCTAGCTGCTGTTCCGGCTGGGGTTTCTCCACCTA
GGGCCGTTCCGGCCCGCTCA

Product: putative exported p60 protein homologue

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVSAGAPGDPLAVANASLQVTAQATQTTLDLGKQFLGR
LGINFGGDPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAF
AGVGVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVTVSSVRKAGMTPFVTRIIE
S

Sequences:

>Translated_241_residues
MRHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVSAGAPGDPLAVANASLQVTAQATQTTLDLGKQFLGR
LGINFGGDPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAF
AGVGVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVTVSSVRKAGMTPFVTRIIE
S
>Mature_241_residues
MRHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVSAGAPGDPLAVANASLQVTAQATQTTLDLGKQFLGR
LGINFGGDPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAF
AGVGVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVTVSSVRKAGMTPFVTRIIE
S

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=112, Percent_Identity=35.7142857142857, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 24762; Mature: 24762

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVSAGAPGDPLAVANASL
CCCCCEEEEEEHHHHHHHHCEEEEEEECCCCCCCCCCCCCCHHCCCCCCCCCEEEECCEE
QVTAQATQTTLDLGKQFLGRLGINFGGDPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGG
EEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCC
AQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAFAGVGVLIPRFSGDQYNAGRH
CEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCC
LTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVTVSSVRKAGMTPFVTRIIE
CCCCCCCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCEEEHHHHHHCCCCHHHHHHHC
S
C
>Mature Secondary Structure
MRHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVSAGAPGDPLAVANASL
CCCCCEEEEEEHHHHHHHHCEEEEEEECCCCCCCCCCCCCCHHCCCCCCCCCEEEECCEE
QVTAQATQTTLDLGKQFLGRLGINFGGDPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGG
EEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCC
AQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAFAGVGVLIPRFSGDQYNAGRH
CEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCC
LTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVTVSSVRKAGMTPFVTRIIE
CCCCCCCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCEEEHHHHHHCCCCHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]