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The map label for this gene is iap [H]

Identifier: 221230447

GI number: 221230447

Start: 2192525

End: 2193964

Strand: Reverse

Name: iap [H]

Synonym: MLBr_01812

Alternate gene names: 221230447

Gene position: 2193964-2192525 (Counterclockwise)

Preceding gene: 221230448

Following gene: 221230446

Centisome position: 67.13

GC content: 62.71

Gene sequence:

>1440_bases
ATGAAACGGCCCCGCCGTGGCTCTGTTTCGCGACCGACCGCACGGTTTGTGCGGCCGGCCATTCCGTCACTCGTGAGTGC
GGCCCTACTGGTATCCCTCCCGGTGCTGGCGACCGCTGATCCAGATGGAGACAACTTAGGCACCTTGATTGCCGACGTCG
CCAAGGTCAACCAGCGCCTAGAAGATCTCGGCGCGGCCATCGAGACCGAAGAGCAAAGTGTCAACAAGGCGATGGTTAGT
GTGGAGATGGCCCGGGACAACGCGGTAGCGGCCGAACACGATTGCGAGGTTAGCCAACAGTCGGTCAAGGACGCGAATAC
GGCCATCAATGCTGCTCAGCATCGGTTTGATAGCTTCGCAGCAGCCACATATATGAATGGCCCGTCGGGCAGTTACCTGA
CTGCGACCAGCCCGGATGACATTATTGCCACCGCGACCGCCGCCAGGACGCTCACTGCCAGTTCCCAGGCGGTGATGGCC
AATCTGCAGCGGGCCCGGACTGAGCAGGTGAACAAGGAGTCGGCTGCGCGGCTGGCCAAGCAAAAGGCCGATAAGGCCGC
TGACGATGCAAAGGCCAGCATGGATGCCGCGGTGGCGGCACTCACCGCGTCCAAGCGCAAATTTGATGAGCAGCGGGACG
AAGTTAATCGCCTGGCTGCTGAGCGTGACGAGGCTCAGGCCAGGCTCGAAGTGGCCCAAATAGCGGCAGCAACGTGGGTG
CCAGGGATGGGAGGGCATGGCACGCCACCGTTCGGTGACCGGTGGGAACCTGGTTCGCCAGCTTCAGCTGGCCCGGCCGG
GGGCCGCAAATGGGACGGCTGGGATCCCACGCTGCCGCAGGTACCCAGCGCCAACGTCCCGGGAGACCCGATCGCAGTGA
TCAACCAGGTGTTGGGGTACGCGGCGACTTCGACGCAGGTCACCGCCAGCATGGGGCGCAACTTCTTGCAGCAACTGGGC
ATCTTGAAACCGAACGACACTGGTATCACTAACGCCCCGATTGGTTCGACGCAGGGACGTATTCCGCGGGTTTACGGGCG
GCAGGCCTCCGAATACGTGATCCGTCGCGGGATATCGCAGATCGGCGTGCCCTACTCCTGGGGTGGTGGCAACGCAGCTG
GCCCGAGTAGGGGAATAGACTCGGGTGCTGGGATTACCGGCTTCGACTGTTCGGGGCTAGTTTTGTATTCTTTCGCCGGG
GTGGGCATCAGGCTGCCGCACTACTCGGGCTCGCAGTACAACCTGGGCCGCAAGATCCCGTCTGCTCAGATGCGCCGCGG
CGACGTCATCTTCTACGGCCCGGGCGGCAGCCAGCACGTGACGATCTACCTCGGCCATGGCCAGATGCTCGAGGCTCCGG
ACATCGGCTTGAGGGTGCGTGTTGCACCTGTGCGCACCAGTGGCATGACTCCGTATGTGGTCCGCTACATCGAATACTAA

Upstream 100 bases:

>100_bases
TGACGTACGGTGCGAATAATGCTCATGTTGTCATCGGCGTTTCGCGAAAGTCGTGGTTGGCGCCGTCCGTCCGTGTTGAG
CCATAGGAGATTCCAGTCGA

Downstream 100 bases:

>100_bases
ACGAGGCTGAATATCAACGAGGAGCTATGCGCCACAAGAATTTTCGCCTGATCAATCTAGCCGGGCTCACCGCGATGGTG
GCCGGGTTGATTATCGTTGT

Product: putative exported p60 protein homologue

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKRPRRGSVSRPTARFVRPAIPSLVSAALLVSLPVLATADPDGDNLGTLIADVAKVNQRLEDLGAAIETEEQSVNKAMVS
VEMARDNAVAAEHDCEVSQQSVKDANTAINAAQHRFDSFAAATYMNGPSGSYLTATSPDDIIATATAARTLTASSQAVMA
NLQRARTEQVNKESAARLAKQKADKAADDAKASMDAAVAALTASKRKFDEQRDEVNRLAAERDEAQARLEVAQIAAATWV
PGMGGHGTPPFGDRWEPGSPASAGPAGGRKWDGWDPTLPQVPSANVPGDPIAVINQVLGYAATSTQVTASMGRNFLQQLG
ILKPNDTGITNAPIGSTQGRIPRVYGRQASEYVIRRGISQIGVPYSWGGGNAAGPSRGIDSGAGITGFDCSGLVLYSFAG
VGIRLPHYSGSQYNLGRKIPSAQMRRGDVIFYGPGGSQHVTIYLGHGQMLEAPDIGLRVRVAPVRTSGMTPYVVRYIEY

Sequences:

>Translated_479_residues
MKRPRRGSVSRPTARFVRPAIPSLVSAALLVSLPVLATADPDGDNLGTLIADVAKVNQRLEDLGAAIETEEQSVNKAMVS
VEMARDNAVAAEHDCEVSQQSVKDANTAINAAQHRFDSFAAATYMNGPSGSYLTATSPDDIIATATAARTLTASSQAVMA
NLQRARTEQVNKESAARLAKQKADKAADDAKASMDAAVAALTASKRKFDEQRDEVNRLAAERDEAQARLEVAQIAAATWV
PGMGGHGTPPFGDRWEPGSPASAGPAGGRKWDGWDPTLPQVPSANVPGDPIAVINQVLGYAATSTQVTASMGRNFLQQLG
ILKPNDTGITNAPIGSTQGRIPRVYGRQASEYVIRRGISQIGVPYSWGGGNAAGPSRGIDSGAGITGFDCSGLVLYSFAG
VGIRLPHYSGSQYNLGRKIPSAQMRRGDVIFYGPGGSQHVTIYLGHGQMLEAPDIGLRVRVAPVRTSGMTPYVVRYIEY
>Mature_479_residues
MKRPRRGSVSRPTARFVRPAIPSLVSAALLVSLPVLATADPDGDNLGTLIADVAKVNQRLEDLGAAIETEEQSVNKAMVS
VEMARDNAVAAEHDCEVSQQSVKDANTAINAAQHRFDSFAAATYMNGPSGSYLTATSPDDIIATATAARTLTASSQAVMA
NLQRARTEQVNKESAARLAKQKADKAADDAKASMDAAVAALTASKRKFDEQRDEVNRLAAERDEAQARLEVAQIAAATWV
PGMGGHGTPPFGDRWEPGSPASAGPAGGRKWDGWDPTLPQVPSANVPGDPIAVINQVLGYAATSTQVTASMGRNFLQQLG
ILKPNDTGITNAPIGSTQGRIPRVYGRQASEYVIRRGISQIGVPYSWGGGNAAGPSRGIDSGAGITGFDCSGLVLYSFAG
VGIRLPHYSGSQYNLGRKIPSAQMRRGDVIFYGPGGSQHVTIYLGHGQMLEAPDIGLRVRVAPVRTSGMTPYVVRYIEY

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=124, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786421, Length=119, Percent_Identity=32.7731092436975, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 50555; Mature: 50555

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPRRGSVSRPTARFVRPAIPSLVSAALLVSLPVLATADPDGDNLGTLIADVAKVNQRL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHH
EDLGAAIETEEQSVNKAMVSVEMARDNAVAAEHDCEVSQQSVKDANTAINAAQHRFDSFA
HHHHHHHHHHHHHHHHHHHHEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AATYMNGPSGSYLTATSPDDIIATATAARTLTASSQAVMANLQRARTEQVNKESAARLAK
HHHCCCCCCCCEEEECCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHH
QKADKAADDAKASMDAAVAALTASKRKFDEQRDEVNRLAAERDEAQARLEVAQIAAATWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGMGGHGTPPFGDRWEPGSPASAGPAGGRKWDGWDPTLPQVPSANVPGDPIAVINQVLGY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
AATSTQVTASMGRNFLQQLGILKPNDTGITNAPIGSTQGRIPRVYGRQASEYVIRRGISQ
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHH
IGVPYSWGGGNAAGPSRGIDSGAGITGFDCSGLVLYSFAGVGIRLPHYSGSQYNLGRKIP
HCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEECCCCCCCCCCCCCCCC
SAQMRRGDVIFYGPGGSQHVTIYLGHGQMLEAPDIGLRVRVAPVRTSGMTPYVVRYIEY
HHHHCCCCEEEECCCCCCEEEEEECCCCEECCCCCCEEEEEEEECCCCCCHHHHHEECC
>Mature Secondary Structure
MKRPRRGSVSRPTARFVRPAIPSLVSAALLVSLPVLATADPDGDNLGTLIADVAKVNQRL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHH
EDLGAAIETEEQSVNKAMVSVEMARDNAVAAEHDCEVSQQSVKDANTAINAAQHRFDSFA
HHHHHHHHHHHHHHHHHHHHEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AATYMNGPSGSYLTATSPDDIIATATAARTLTASSQAVMANLQRARTEQVNKESAARLAK
HHHCCCCCCCCEEEECCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHH
QKADKAADDAKASMDAAVAALTASKRKFDEQRDEVNRLAAERDEAQARLEVAQIAAATWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGMGGHGTPPFGDRWEPGSPASAGPAGGRKWDGWDPTLPQVPSANVPGDPIAVINQVLGY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
AATSTQVTASMGRNFLQQLGILKPNDTGITNAPIGSTQGRIPRVYGRQASEYVIRRGISQ
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHH
IGVPYSWGGGNAAGPSRGIDSGAGITGFDCSGLVLYSFAGVGIRLPHYSGSQYNLGRKIP
HCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEECCCCCCCCCCCCCCCC
SAQMRRGDVIFYGPGGSQHVTIYLGHGQMLEAPDIGLRVRVAPVRTSGMTPYVVRYIEY
HHHHCCCCEEEECCCCCCEEEEEECCCCEECCCCCCEEEEEEEECCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]