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The map label for this gene is mutT1 [H]

Identifier: 221230370

GI number: 221230370

Start: 2027640

End: 2028575

Strand: Direct

Name: mutT1 [H]

Synonym: MLBr_01682

Alternate gene names: 221230370

Gene position: 2027640-2028575 (Clockwise)

Preceding gene: 221230369

Following gene: 221230382

Centisome position: 62.04

GC content: 58.23

Gene sequence:

>936_bases
GTGGCGATCTGGAACTCGTCCTGTCAATGGCCAAAGAGTCAAATCGTGTACGCTGCGGGGGCGGTGTTGTGGCGACCAGG
CAATTCCGACCCGGCCGTCGAGATTGCCGTGATCCATCGTCCCCGTTACGATGACTGGTCACTGTCCAAGGGCAAAGTTG
ACCCCGGTGAGACCGCTCCGATGGCGGCCGTGCGCGAAGTGTTCGAGGAGACAGGCCATCACGCTACCCTTGGCGCGCGG
CTCGTCGTGGTGAATTACCCAATCGGTCAACACGTCAAGAAGGTGTACTACTGGGCAGCTCGCAGCATTGAGGGACAATT
TGTCCCGGGCAGCGAGGTCGACGAGCTGCTCTGGCTGCCGGTTGTCGACGCAATGAAAAAACTTGATTACGTGCAGGATC
GAAAAGTCCTGCGCCAGTTCGCTAAACAACCAGCTTATACGCGGACCGTGTTGATCGTCCGGCACGGAACCGCCGGCCGG
AAGTCACGCTTATCGGAGGATGACACCAAACGACCTTTGGACAAACAGGGTCGCGCACAAGCGGAGGCATTGATTGGACA
GCTGCTGGCTTTTGGTGCCACCGATGTGTATGCGGCCGACCAGTTACACTGTCATCAGACAGTAGAACCGCTCGCCGCAG
AACTAGGTGTGCCGATCCACAACGAGCCCAGTTTGACCAAGGAGGCCTTCGCCAAAAACCCCAAACGTGGCCTACACCGA
GTGTTGCGGATCGCGGCGCAGTCAGGAACACCGGTGATCTGCTTGCAGGGCAAGATAATTCCAGACCTGATCGCGTGGTG
GTGCGAACGCGATGGAGTGCGCCCCAAAAAATCGCACAATTACAAGGGCAGTACTTGGGTGCTGTCACTATTAGCCGGTC
AGCTAGTGGCTGTCGACCACGTCGGCAGCACGCTCGCAGCCAACGTACAGCCCTAA

Upstream 100 bases:

>100_bases
GGAACGGCACCGCAGCCGCTGACGCTGTGTGATGATCTTTTCGGCCACATCCACAATGTGTGAGCTACCCTGACTCAATT
GACCTGCAAGGATGTTAATG

Downstream 100 bases:

>100_bases
CACGCAGATACCCTCCGGGTGAAAGTAACGCCTACCGAAAGGTATCTGCGTTAGACTGTCTATTTTCTTTACTTGCGACC
CCGCTTAGCTGCGGTAACCT

Product: hypothetical protein

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MAIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSKGKVDPGETAPMAAVREVFEETGHHATLGAR
LVVVNYPIGQHVKKVYYWAARSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVLRQFAKQPAYTRTVLIVRHGTAGR
KSRLSEDDTKRPLDKQGRAQAEALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHR
VLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVDHVGSTLAANVQP

Sequences:

>Translated_311_residues
MAIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSKGKVDPGETAPMAAVREVFEETGHHATLGAR
LVVVNYPIGQHVKKVYYWAARSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVLRQFAKQPAYTRTVLIVRHGTAGR
KSRLSEDDTKRPLDKQGRAQAEALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHR
VLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVDHVGSTLAANVQP
>Mature_310_residues
AIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSKGKVDPGETAPMAAVREVFEETGHHATLGARL
VVVNYPIGQHVKKVYYWAARSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVLRQFAKQPAYTRTVLIVRHGTAGRK
SRLSEDDTKRPLDKQGRAQAEALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHRV
LRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVDHVGSTLAANVQP

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX; PF00300 PGAM [H]

EC number: NA

Molecular weight: Translated: 34365; Mature: 34234

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSKGKVDPGETAP
CCCCCCCCCCCHHHEEEECCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCH
MAAVREVFEETGHHATLGARLVVVNYPIGQHVKKVYYWAARSIEGQFVPGSEVDELLWLP
HHHHHHHHHHCCCEEEECEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VVDAMKKLDYVQDRKVLRQFAKQPAYTRTVLIVRHGTAGRKSRLSEDDTKRPLDKQGRAQ
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHCCCCCHHCCCCCHHHHHH
AEALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHR
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHH
VLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVDH
HHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEHH
VGSTLAANVQP
CCCHHCCCCCC
>Mature Secondary Structure 
AIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSKGKVDPGETAP
CCCCCCCCCCHHHEEEECCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCH
MAAVREVFEETGHHATLGARLVVVNYPIGQHVKKVYYWAARSIEGQFVPGSEVDELLWLP
HHHHHHHHHHCCCEEEECEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VVDAMKKLDYVQDRKVLRQFAKQPAYTRTVLIVRHGTAGRKSRLSEDDTKRPLDKQGRAQ
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHCCCCCHHCCCCCHHHHHH
AEALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHR
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHH
VLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVDH
HHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEHH
VGSTLAANVQP
CCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]