Click here to switch to the map view.

The map label for this gene is ppk

Identifier: 221230369

GI number: 221230369

Start: 2025342

End: 2027561

Strand: Direct

Name: ppk

Synonym: MLBr_01681

Alternate gene names: 221230369

Gene position: 2025342-2027561 (Clockwise)

Preceding gene: 221230368

Following gene: 221230370

Centisome position: 61.97

GC content: 59.46

Gene sequence:

>2220_bases
ATGATGAGCAATGATCTTTTGGTGACCGACATCGAAGCTGAGGCCCGTACCGAAGAGAATATATGGCATTCAGACAACTC
CGCCCTCGCAGCACCGCCCGCGGCGACCACCTCTGCGAGTCAGGACCAGCTGCCCGACGACCGCTACCTCAACCGGGAAT
CAAGTTGGCTGGATTTCAATGCGCGTGTGCTCGCACTAGCCGCCGATAACTCGTTGCCTTTGTTGGAGCGAGCCAAGTTT
CTGGCTATCTTCGCATCCAATCTCGACGAGTTCTACATGGTTCGAGTCGCCGGCCTCAAGCGCCGCGACGAGATGGACTT
GTCGGTGCGCTCTGCTGACGGTCTCACCCCACGTGAGCAACTGAGCCGCATAGGCGAGCAGACCCAATGGATCGCCAGCC
GGCACGCGCGGGTGTTCCTCGATTCGGTGTTACCCGCACTCGGTGAGGAGGGTATCTACATTGTCACGTGGACGGATTTA
GATCAGGCCGAACGTGACCAGTTATCGACCTATTTCAACGAGCAGGTCTTCCCCGTCCTGACACCACTGGCTGTCGATCC
CGCCCACCCGTTTCCGTTTGTCAGCGGGTTAAGTCTGAACCTGGCTGTCACCGTCAAGCAACCCGAAGACGGTACCCAGC
ATTTCGCCCGGGTCAAAGTGCCTAACAACGTCGATCGATTCGTAGAACTCGCTAACCGCGGGGCGGTCAGAGATACCTCT
GCCGGAGATGAAGGTCAGCTCATTCACCGGTTCCTGCCCATGGAGGAGCTGATCGCGGCATTCCTTCCGGTGCTCTTCCC
TGGCACGGAAATCGTCGAGCATCATGCATTCCGCATTACCCGCAACGCTGACTTCGAGGTTGAAGAAGACCGTGACGAAG
ACCTACTACAGGCGCTGGAACGAGAATTGGCGCGTCGACGGTTCGGTTCGCCGGTGCGACTCGAGATCGCCGACGACATG
ACCGAGAGCATGCTGGAACTGCTGTTGCGGGAACTCGACGTGCATCCCAGCGACGTCATCGAAGTGCCCGGGCTGCTTGA
CCTGTCGTCGTTGTGGCAAATTTACGGGCTGGACCGACCCGCACTCAAAGACCGCGCATTCATTCCCGACACTCATCCCG
CTTTCGCCGAACGGGAAACTCCCAAGAGCATCTTCGCGACGCTGCGCGAAGGCGATGTTCTGGTGCACCATCCCTATCAC
TCGTTTGCCACCAGCGTGCAGAGATTCATTGAACAGGCCACCGCCGACCCCGATGTGCTGGCGATCAAACAAACGCTGTA
CCGCACCTCCGGTGATTCACCGATCGTGCTGGCGCTCATCGAAGCTGCCGAGGCAGGAAAGCAAGTGGTGGCACTGGTCG
AAATCAAGGCTCGCTTTGACGAGCAGGCCAACATCCGGTGGGCGCGCGCGCTGGAACACGCAGGCGTGCATGTGGTGTAC
GGGATCGTTGGGCTCAAGACACACTGCAAGACCTGCCTCGTGGTGCGCCGTGAGGGCCCGACGATCCGGCGGTACTGCCA
TATCGGAACCGGCAACTACAACAGCAAGACCGCTCGACTGTACGAAGATGTCGGTCTGTTGACCGCAGCACCCGATATCG
GCGCCGACTTGACTGACTTGTTCAACTCGCTTACCGGCTACTCGCGTAAGCTGGCTTACCGCAACCTTCTGGTGGCACCG
TATGGAATTCGCCGAGGCATTATCGAGCGGGTCGAGCGCGAGGTGGCCGCCCATCGCGAATCCGGCCCCCAAACCGGTAA
GGGCCTGATCCGACTCAAGATGAACGCTCTGGTCGACGAACAAGTTATCGATGCGCTGTATCGCGCGTCACAGGCAGGCG
TGCGGGTCGAGGTGGTGGTGCGCGGCATCTGCGCACTACGCCCAGGCACCGAAGGTTTTTCGGAAAACATTTTCGTCCGC
TCGATTCTCGGCCGTTTCCTCGAGCATTCACGGATCATCCATTTCCGAGCCATCGATGAGTTCTGGATCGGAAGCGCCGA
CATGATGCACCGCAACCTAGATCGACGAGTCGAGGTGCTGGCGCAAGTTAAAGACTCGAGGCTGACCGCGCAGCTAGATG
AGTTGTTGAAGTCCGCGCTGGACCCGTTCACCCGGTGTTGGGAACTGCGACCCGACGGGCAGTGGACCGCTTCGCCGCAG
AAAGGCCAGCAGGTGCGCGACCACCAAGAATCGTTGATGGAACGGCACCGCAGCCGCTGA

Upstream 100 bases:

>100_bases
TGGTCGCACATCTTTAGCCCCAACCAGCTACAGGATCCCAAATGGTAAACAGCACACCAACGCGGAATGAATGGCCACAG
CGTGATAGCAGCACCATCGG

Downstream 100 bases:

>100_bases
CGCTGTGTGATGATCTTTTCGGCCACATCCACAATGTGTGAGCTACCCTGACTCAATTGACCTGCAAGGATGTTAATGGT
GGCGATCTGGAACTCGTCCT

Product: polyphosphate kinase

Products: NA

Alternate protein names: ATP-polyphosphate phosphotransferase; Polyphosphoric acid kinase

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFNARVLALAADNSLPLLERAKF
LAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQLSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDL
DQAERDQLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTS
AGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDM
TESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYH
SFATSVQRFIEQATADPDVLAIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVY
GIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLAYRNLLVAP
YGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVR
SILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQ
KGQQVRDHQESLMERHRSR

Sequences:

>Translated_739_residues
MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFNARVLALAADNSLPLLERAKF
LAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQLSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDL
DQAERDQLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTS
AGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDM
TESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYH
SFATSVQRFIEQATADPDVLAIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVY
GIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLAYRNLLVAP
YGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVR
SILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQ
KGQQVRDHQESLMERHRSR
>Mature_739_residues
MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFNARVLALAADNSLPLLERAKF
LAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQLSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDL
DQAERDQLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTS
AGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDM
TESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYH
SFATSVQRFIEQATADPDVLAIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVY
GIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLAYRNLLVAP
YGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVR
SILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQ
KGQQVRDHQESLMERHRSR

Specific function: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)

COG id: COG0855

COG function: function code P; Polyphosphate kinase

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyphosphate kinase family

Homologues:

Organism=Escherichia coli, GI1788847, Length=663, Percent_Identity=33.7858220211161, Blast_Score=351, Evalue=9e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPK_MYCLB (B8ZS08)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503785.1
- ProteinModelPortal:   B8ZS08
- EnsemblBacteria:   EBMYCT00000085046
- GeneID:   7326786
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016805
- HOGENOM:   HBG341268
- OMA:   NYHAGNA
- ProtClustDB:   PRK05443
- HAMAP:   MF_00347
- InterPro:   IPR003414
- PIRSF:   PIRSF015589
- TIGRFAMs:   TIGR03705

Pfam domain/function: PF02503 PP_kinase

EC number: =2.7.4.1

Molecular weight: Translated: 83288; Mature: 83288

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: ACT_SITE 488-488 ACT_SITE 507-507

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFN
CCCCCEEEEECCHHHCCCCCCEECCCCCEECCCCCCCCCCCCCCCCHHHCCCCCCEEECC
ARVLALAADNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQ
CEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCHHHH
LSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDLDQAERDQLSTYFNEQVFPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHH
TPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTS
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHCCCCCCCC
AGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALE
CCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHH
RELARRRFGSPVRLEIADDMTESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRP
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHCCCCC
ALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYHSFATSVQRFIEQATADPDVL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCHH
AIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVY
HHHHHHHHCCCCCCEEEEEEHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHCCEEEEH
GIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDL
HHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEECCCCCCCHHHH
FNSLTGYSRKLAYRNLLVAPYGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDE
HHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHH
QVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVRSILGRFLEHSRIIHFRAIDE
HHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEHHH
FWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KGQQVRDHQESLMERHRSR
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFN
CCCCCEEEEECCHHHCCCCCCEECCCCCEECCCCCCCCCCCCCCCCHHHCCCCCCEEECC
ARVLALAADNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQ
CEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCHHHH
LSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDLDQAERDQLSTYFNEQVFPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHH
TPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTS
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHCCCCCCCC
AGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALE
CCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHH
RELARRRFGSPVRLEIADDMTESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRP
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHCCCCC
ALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYHSFATSVQRFIEQATADPDVL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCHH
AIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVY
HHHHHHHHCCCCCCEEEEEEHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHCCEEEEH
GIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDL
HHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEECCCCCCCHHHH
FNSLTGYSRKLAYRNLLVAPYGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDE
HHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHH
QVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVRSILGRFLEHSRIIHFRAIDE
HHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEHHH
FWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KGQQVRDHQESLMERHRSR
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA