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The map label for this gene is nadD

Identifier: 221230240

GI number: 221230240

Start: 1747876

End: 1748520

Strand: Reverse

Name: nadD

Synonym: MLBr_01454

Alternate gene names: 221230240

Gene position: 1748520-1747876 (Counterclockwise)

Preceding gene: 221230241

Following gene: 221230239

Centisome position: 53.5

GC content: 60.62

Gene sequence:

>645_bases
ATGGGTGGGACGTTCGACCCCATCCACTATGGTCACCTGGTTGCTGCAAGTGAGGTGGCGCACATGTTTGAACTCGATGA
AGTGATGTTTGTGCCCAGCGGGCAGCCTTGGCAAAAGGGTCGGCACGTCTCCGCTGCTGAGGACCGGTACTTGATGACGG
TGATCGCAACCGCGTCCAATCCGCGTTTCTCGGTGAGCAGAGTCGACATCGACCGCACCGGCCCCACCTACACCAGGGAT
ACGGTGCACGATCTGCATGCCCTCAACCCTGACTCCGAACTGTACTTCATTACCGGCGCCGACGCGCTGGCTTCCATTCT
GTCTTGGCAAGGTTGGGACGAGCTTTTCGACTTGGCGCGATTCGTCGGGGTCAGCCGACCCGGATATGAGCTGGGCCAAG
AGCACATCACCGGGGTTATGGGCGAGCTGCCCGCAGACGCGTTGACATTGGTCGAAATCCCGGCGCTGGCGATCTCGTCG
ACCGACTGCCGGCAACGTGTCGAGCAGCGTCAACCGCTGTGGTATCTGATGCCCGACGGTGTCGTGCAGTACGTGTTCAA
GCGCCGACTCTATCGTGGACCTCACGGCGTGGCTGGGACTGGGCGCTTAACGACGCCCAGTCTGGTCGTCGGAAACAACA
CATGA

Upstream 100 bases:

>100_bases
ACAATTTGACTGCCGCGACTAACTAGCGCGATCACGACCTTCGCGATGCGCTCAAGTAAACTGGCGAATTGTGCAAAAAC
ACTTTCGTAGGCTGGGAATC

Downstream 100 bases:

>100_bases
ATGCCACAAAGGAGGCGATCGACATGGCAACAGTGGCCGCCGCAGCGGCCGCCGCGAAGCTAGCTAACGACGTTGTCGTT
ATCGATGTCTCCGAGCAACT

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MGGTFDPIHYGHLVAASEVAHMFELDEVMFVPSGQPWQKGRHVSAAEDRYLMTVIATASNPRFSVSRVDIDRTGPTYTRD
TVHDLHALNPDSELYFITGADALASILSWQGWDELFDLARFVGVSRPGYELGQEHITGVMGELPADALTLVEIPALAISS
TDCRQRVEQRQPLWYLMPDGVVQYVFKRRLYRGPHGVAGTGRLTTPSLVVGNNT

Sequences:

>Translated_214_residues
MGGTFDPIHYGHLVAASEVAHMFELDEVMFVPSGQPWQKGRHVSAAEDRYLMTVIATASNPRFSVSRVDIDRTGPTYTRD
TVHDLHALNPDSELYFITGADALASILSWQGWDELFDLARFVGVSRPGYELGQEHITGVMGELPADALTLVEIPALAISS
TDCRQRVEQRQPLWYLMPDGVVQYVFKRRLYRGPHGVAGTGRLTTPSLVVGNNT
>Mature_213_residues
GGTFDPIHYGHLVAASEVAHMFELDEVMFVPSGQPWQKGRHVSAAEDRYLMTVIATASNPRFSVSRVDIDRTGPTYTRDT
VHDLHALNPDSELYFITGADALASILSWQGWDELFDLARFVGVSRPGYELGQEHITGVMGELPADALTLVEIPALAISST
DCRQRVEQRQPLWYLMPDGVVQYVFKRRLYRGPHGVAGTGRLTTPSLVVGNNT

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=206, Percent_Identity=30.5825242718447, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_MYCLE (Q9CBZ8)

Other databases:

- EMBL:   AL583922
- PIR:   G87090
- RefSeq:   NP_302026.1
- ProteinModelPortal:   Q9CBZ8
- SMR:   Q9CBZ8
- EnsemblBacteria:   EBMYCT00000029187
- GeneID:   909482
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1454
- NMPDR:   fig|272631.1.peg.898
- Leproma:   ML1454
- GeneTree:   EBGT00050000016650
- HOGENOM:   HBG739448
- OMA:   IPPHKNT
- ProtClustDB:   PRK00071
- BioCyc:   MLEP272631:ML1454-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 23700; Mature: 23569

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGTFDPIHYGHLVAASEVAHMFELDEVMFVPSGQPWQKGRHVSAAEDRYLMTVIATASN
CCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHCCCCCCCCCCCEEEEEEEECCC
PRFSVSRVDIDRTGPTYTRDTVHDLHALNPDSELYFITGADALASILSWQGWDELFDLAR
CCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHCCCCHHHHHHHHH
FVGVSRPGYELGQEHITGVMGELPADALTLVEIPALAISSTDCRQRVEQRQPLWYLMPDG
HHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCHHHCCCHHHHHHHHHCCCEEEECCHH
VVQYVFKRRLYRGPHGVAGTGRLTTPSLVVGNNT
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure 
GGTFDPIHYGHLVAASEVAHMFELDEVMFVPSGQPWQKGRHVSAAEDRYLMTVIATASN
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHCCCCCCCCCCCEEEEEEEECCC
PRFSVSRVDIDRTGPTYTRDTVHDLHALNPDSELYFITGADALASILSWQGWDELFDLAR
CCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHCCCCHHHHHHHHH
FVGVSRPGYELGQEHITGVMGELPADALTLVEIPALAISSTDCRQRVEQRQPLWYLMPDG
HHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCHHHCCCHHHHHHHHHCCCEEEECCHH
VVQYVFKRRLYRGPHGVAGTGRLTTPSLVVGNNT
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002