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The map label for this gene is ftsW [C]

Identifier: 221229910

GI number: 221229910

Start: 1081743

End: 1083347

Strand: Direct

Name: ftsW [C]

Synonym: MLBr_00913

Alternate gene names: 221229910

Gene position: 1081743-1083347 (Clockwise)

Preceding gene: 221229909

Following gene: 221229911

Centisome position: 33.1

GC content: 61.31

Gene sequence:

>1605_bases
GTGGGTAACGCGCTGGGTCGGGATAGGGGTCGGGGCACGGGAGATAACAACAGTGTGCAGGCCGCCACGACCGTGGAGGC
GGTTGAGCCCGGCACTGCTACGACCGGCGAAGTGTCCGAAGCGGAGGCCAAAAGAGCCGGCTCTCTGAGGGCCGGAGTAC
GCGGCCCTCAGACTCGGTTCGATGCCTGGCTGGGCCGGCCGATGGCCTCCTTTCATCTGATAATTGCTGTGGCTGGATTG
CTGACGGCATTAGGTCTGATAATGGTGTTGTCGGCCTCAGGTGTGCGGTCCTACGGCGACGACGGATCGGCTTGGATCAT
TTTCGGCAAACAGGTTTTGTGGACGATCATCGGTCTCATCGGTGGTTATTCCTCATTGTGGATGTCGATACGGTTCATCC
GGCGCATTGCATTCTTTAGTTATGTCATCACCATCATTTTGCTGGTGCTGGTGCTCATCCCGGGAATTGGCAATCTCGCC
AACGGGTCGCGTAAATGGTTTGTGATCGCCGGCTTTTCGATGCAGCCTTCCGAGCTGGCCAAGATTGCTTTCGTCATTTG
GGGTGCGCATCTGCTGGCTGCTCGCCGGATGGAACGAGCGTCGCTGCGCGAGATGCTTATTCCGTTGGTGCCGGCCGCGG
TCATCGCGCTGGGACTGATCGTGGCTCAGCCTGATCTCGGGCAGACGGTGTCGCTGGGCATCATCCTTTTGGCCCTGCTC
TGGTACGCTGGGCTGCCGCTGCGCGTTTTCATCACATCGTTGCTCGCGGTCTTTATTGCGGGAGCGATCCTGGCGATGTC
CGCGGGTTATCGGTCAGAACGGGTGCGGTCCTGGATGAATCCCGAGGCCGATCCTCAAGACACCGGCTACCAGGCTCGGC
AAGCAAAATTCGCGCTGGCCCACGGAGGCATTTTCGGCGACGGTCTTGGCCAGGGTGTTGCCAAGTGGAACTATCTGCCC
AACGCTCACAACGATTTCATTTTCGCGATCATCGGCGAGGAACTCGGCTTGGTTGGTGCGTTGGGACTGTTGGGACTTTT
CGGGCTGTTCGCCTACACTGGAATGCGGATCGCGCGGCGGTCGGCCGATCCTTTCCTGCGGCTGCTGACCGCCACCACGA
CTATGTGGGTGCTGGGCCAGGCGTTTATCAACATCGGCTATGTGATCGGGGTGTTGCCGGTGACTGGTTTGCAGCTGCCT
TTCATCTCTGCCGGTGGAACATCGGCGGCAGCAATACTTTTCATGATCGGCATCATGGCCAACGCGGCTCGCCACGAGCC
AGAGGCGGTGGCGGCGCTGCGGGCCGGGCGTGATGACAAGGTGAACCAGCTGCTACGGCTGCCGCTGCCGGTGCCGTATC
TGCCACCCCGGGTGGAGACGTTCCGCGACCGCAAACAGGTTCGCCCGCAACCCGGCAAGGCGTCGGTTGGCCGCAAGCCC
GCCCGCAAAGCCCCCCGGGAGCCTGACCGGCCGCTGCGGCCGGCATTCCCCCGAGTGGCTGATCGACTGGAGCACCGATC
AGGGCAGTATAGAGCTGGTCAGCTGCGTGCCGGTCAACGTTATACACCGCGCGTTCGTGTATTCGAAGGTCAGCGTTACG
GGTGA

Upstream 100 bases:

>100_bases
GCTGGCACCGGCCGGCGCGTCGTTCGACCAATTTAGCGGTTATGCCGACCGCGGTGACACATTCGCAACTGCCGTGCGCG
CAGCGATCCGGTAGGTGGGC

Downstream 100 bases:

>100_bases
ACAACTCGGTTAGGGAGCCGACCCGCGGGCGAAGGGGCAGCCCGCCGGTCGCCGATGCCGCATTATCGGTTAATCCCCCC
TTGTCGGTTGTGCTGGCGGG

Product: putative cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MGNALGRDRGRGTGDNNSVQAATTVEAVEPGTATTGEVSEAEAKRAGSLRAGVRGPQTRFDAWLGRPMASFHLIIAVAGL
LTALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLIGGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLA
NGSRKWFVIAGFSMQPSELAKIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLIVAQPDLGQTVSLGIILLALL
WYAGLPLRVFITSLLAVFIAGAILAMSAGYRSERVRSWMNPEADPQDTGYQARQAKFALAHGGIFGDGLGQGVAKWNYLP
NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLTATTTMWVLGQAFINIGYVIGVLPVTGLQLP
FISAGGTSAAAILFMIGIMANAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQPGKASVGRKP
ARKAPREPDRPLRPAFPRVADRLEHRSGQYRAGQLRAGQRYTPRVRVFEGQRYG

Sequences:

>Translated_534_residues
MGNALGRDRGRGTGDNNSVQAATTVEAVEPGTATTGEVSEAEAKRAGSLRAGVRGPQTRFDAWLGRPMASFHLIIAVAGL
LTALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLIGGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLA
NGSRKWFVIAGFSMQPSELAKIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLIVAQPDLGQTVSLGIILLALL
WYAGLPLRVFITSLLAVFIAGAILAMSAGYRSERVRSWMNPEADPQDTGYQARQAKFALAHGGIFGDGLGQGVAKWNYLP
NAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLTATTTMWVLGQAFINIGYVIGVLPVTGLQLP
FISAGGTSAAAILFMIGIMANAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQPGKASVGRKP
ARKAPREPDRPLRPAFPRVADRLEHRSGQYRAGQLRAGQRYTPRVRVFEGQRYG
>Mature_533_residues
GNALGRDRGRGTGDNNSVQAATTVEAVEPGTATTGEVSEAEAKRAGSLRAGVRGPQTRFDAWLGRPMASFHLIIAVAGLL
TALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLIGGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLAN
GSRKWFVIAGFSMQPSELAKIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLIVAQPDLGQTVSLGIILLALLW
YAGLPLRVFITSLLAVFIAGAILAMSAGYRSERVRSWMNPEADPQDTGYQARQAKFALAHGGIFGDGLGQGVAKWNYLPN
AHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLTATTTMWVLGQAFINIGYVIGVLPVTGLQLPF
ISAGGTSAAAILFMIGIMANAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQPGKASVGRKPA
RKAPREPDRPLRPAFPRVADRLEHRSGQYRAGQLRAGQRYTPRVRVFEGQRYG

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=336, Percent_Identity=36.6071428571429, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786853, Length=294, Percent_Identity=36.0544217687075, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 57708; Mature: 57577

Theoretical pI: Translated: 11.35; Mature: 11.35

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNALGRDRGRGTGDNNSVQAATTVEAVEPGTATTGEVSEAEAKRAGSLRAGVRGPQTRF
CCCCCCCCCCCCCCCCCCEEEHEEHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHH
DAWLGRPMASFHLIIAVAGLLTALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHH
GGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLANGSRKWFVIAGFSMQPSELA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHH
KIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLIVAQPDLGQTVSLGIILLALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
WYAGLPLRVFITSLLAVFIAGAILAMSAGYRSERVRSWMNPEADPQDTGYQARQAKFALA
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
HGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARR
CCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SADPFLRLLTATTTMWVLGQAFINIGYVIGVLPVTGLQLPFISAGGTSAAAILFMIGIMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHH
NAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQPGKASVGRKP
HHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
ARKAPREPDRPLRPAFPRVADRLEHRSGQYRAGQLRAGQRYTPRVRVFEGQRYG
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GNALGRDRGRGTGDNNSVQAATTVEAVEPGTATTGEVSEAEAKRAGSLRAGVRGPQTRF
CCCCCCCCCCCCCCCCCEEEHEEHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHH
DAWLGRPMASFHLIIAVAGLLTALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHH
GGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLANGSRKWFVIAGFSMQPSELA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHH
KIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLIVAQPDLGQTVSLGIILLALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
WYAGLPLRVFITSLLAVFIAGAILAMSAGYRSERVRSWMNPEADPQDTGYQARQAKFALA
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
HGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARR
CCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SADPFLRLLTATTTMWVLGQAFINIGYVIGVLPVTGLQLPFISAGGTSAAAILFMIGIMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHH
NAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQPGKASVGRKP
HHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
ARKAPREPDRPLRPAFPRVADRLEHRSGQYRAGQLRAGQRYTPRVRVFEGQRYG
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]