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The map label for this gene is murG

Identifier: 221229911

GI number: 221229911

Start: 1083344

End: 1084567

Strand: Direct

Name: murG

Synonym: MLBr_00914

Alternate gene names: 221229911

Gene position: 1083344-1084567 (Clockwise)

Preceding gene: 221229910

Following gene: 221229912

Centisome position: 33.15

GC content: 65.77

Gene sequence:

>1224_bases
GTGAACAACTCGGTTAGGGAGCCGACCCGCGGGCGAAGGGGCAGCCCGCCGGTCGCCGATGCCGCATTATCGGTTAATCC
CCCCTTGTCGGTTGTGCTGGCGGGCGGCGGTACCGCCGGCCATGTGGAGCCCGCAATGGCCGTTGCCGATGCACTCAGAG
CGCTGGATCCACAGGTCCGGATCACCGCGTTGGGCACTTCGCGTGGGCTGGAGACCAGGCTAGTACCCGAGCGTGGCTAC
CACCTCGAGTTGATCACACCGGTGCCATTGCCGCGTAAGCTTACCGGCGACCTGGCCCGGCTCCCATTACGAGTGTGGCG
TGCCGTCCGAGAGACCCGCGCGGTGTTCGAAGTCGTCGAGGCCCATGTGGTGGTGGGTTTCGGTGGGTACGTGGCACTGC
CAGCGTACCTCGCCGCACGTGGTATCCCCAGGGTGCGGCGTCGTATCCCGGTGGTGGTTCACGAGGCCAACGCCCGGGCC
GGCATCGCCAATCGTGTCGGTGTGCGTACTGCCGAACGGGTGCTTTCGGCAGTACCCGGTTCCGGATTACGTGGTGCCGA
GGTGGTGGGAGTGCCGATCCACGCGACCATTACTACGCTGAACCGCCCGGCATTGCGAGCTGACGCCCGCAAGCATTTTG
GCTTCACCGACGACGCGCGGGTGTTGTTGGTTTTCGGTGGTTCTCAGGGTGCAGTTTCGCTGAATCGGGCGGTTGCCGGT
GCTGCCGAGGACCTGGCCGCCTCGGGAGTGGCCGTGCTGCATGCCTACGGACTCAAGAACACCCTCGAGCTGCGCACACC
CGAGTACGGTGAGCCGCCGTACGTCGCGGTGCCCTACCTTGACCGAATGGACTTAGCGTACGCCGCCGCTGACCTGGTGA
TTTGTCGGTCCGGAGCAATGACGGTCGCCGAAGTGTCGGCCGTCGGCTTGCCAGCCATCTATGTACCGTTCCCAATTGGC
AACGGTGAGCAACGGCTCAATGCACTGCCGGTGGTTAACGCCGGCGGCGGCCTGGTGGTCGCCGACGCTGACTTGACGCC
CGGTCTGGTGGCGCGGCAAGTTGTCAGGTTGTTCAGCGATCCGGCGCAGCTGGCGGCAATGACGGCGGCCGCCGCGCGAG
TGGGACATCGCGATGCGGCACATCATGTCGCCAAGGTGGCACTGGATCTGGCACGTGCAGAGCGTGACACGGCGTCAGGA
CGGTCGGCCGGAGGGAAACCGTGA

Upstream 100 bases:

>100_bases
ATCGACTGGAGCACCGATCAGGGCAGTATAGAGCTGGTCAGCTGCGTGCCGGTCAACGTTATACACCGCGCGTTCGTGTA
TTCGAAGGTCAGCGTTACGG

Downstream 100 bases:

>100_bases
ACGCCGGCCAGTTGCCGCCCGAGTTGCAGCGGGTGCACATGGTGGGCATTGGGGGATCCGGGATGTCGGGTATTGCGCGC
ATCCTGTTAGACCGGGGCGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNNSVREPTRGRRGSPPVADAALSVNPPLSVVLAGGGTAGHVEPAMAVADALRALDPQVRITALGTSRGLETRLVPERGY
HLELITPVPLPRKLTGDLARLPLRVWRAVRETRAVFEVVEAHVVVGFGGYVALPAYLAARGIPRVRRRIPVVVHEANARA
GIANRVGVRTAERVLSAVPGSGLRGAEVVGVPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
AAEDLAASGVAVLHAYGLKNTLELRTPEYGEPPYVAVPYLDRMDLAYAAADLVICRSGAMTVAEVSAVGLPAIYVPFPIG
NGEQRLNALPVVNAGGGLVVADADLTPGLVARQVVRLFSDPAQLAAMTAAAARVGHRDAAHHVAKVALDLARAERDTASG
RSAGGKP

Sequences:

>Translated_407_residues
MNNSVREPTRGRRGSPPVADAALSVNPPLSVVLAGGGTAGHVEPAMAVADALRALDPQVRITALGTSRGLETRLVPERGY
HLELITPVPLPRKLTGDLARLPLRVWRAVRETRAVFEVVEAHVVVGFGGYVALPAYLAARGIPRVRRRIPVVVHEANARA
GIANRVGVRTAERVLSAVPGSGLRGAEVVGVPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
AAEDLAASGVAVLHAYGLKNTLELRTPEYGEPPYVAVPYLDRMDLAYAAADLVICRSGAMTVAEVSAVGLPAIYVPFPIG
NGEQRLNALPVVNAGGGLVVADADLTPGLVARQVVRLFSDPAQLAAMTAAAARVGHRDAAHHVAKVALDLARAERDTASG
RSAGGKP
>Mature_407_residues
MNNSVREPTRGRRGSPPVADAALSVNPPLSVVLAGGGTAGHVEPAMAVADALRALDPQVRITALGTSRGLETRLVPERGY
HLELITPVPLPRKLTGDLARLPLRVWRAVRETRAVFEVVEAHVVVGFGGYVALPAYLAARGIPRVRRRIPVVVHEANARA
GIANRVGVRTAERVLSAVPGSGLRGAEVVGVPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
AAEDLAASGVAVLHAYGLKNTLELRTPEYGEPPYVAVPYLDRMDLAYAAADLVICRSGAMTVAEVSAVGLPAIYVPFPIG
NGEQRLNALPVVNAGGGLVVADADLTPGLVARQVVRLFSDPAQLAAMTAAAARVGHRDAAHHVAKVALDLARAERDTASG
RSAGGKP

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=366, Percent_Identity=37.1584699453552, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_MYCLB (B8ZQQ0)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503327.1
- ProteinModelPortal:   B8ZQQ0
- EnsemblBacteria:   EBMYCT00000087104
- GeneID:   7325315
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016957
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 42423; Mature: 42423

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSVREPTRGRRGSPPVADAALSVNPPLSVVLAGGGTAGHVEPAMAVADALRALDPQVR
CCCCCCCCCCCCCCCCCHHCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEE
ITALGTSRGLETRLVPERGYHLELITPVPLPRKLTGDLARLPLRVWRAVRETRAVFEVVE
EEEEECCCCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHVVVGFGGYVALPAYLAARGIPRVRRRIPVVVHEANARAGIANRVGVRTAERVLSAVPG
HEEEEECCHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
SGLRGAEVVGVPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
CCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHHC
AAEDLAASGVAVLHAYGLKNTLELRTPEYGEPPYVAVPYLDRMDLAYAAADLVICRSGAM
CHHHHHHCCCCEEEHHCCCCEEEECCCCCCCCCEEEECCCCHHHHHHHHHHEEEECCCCC
TVAEVSAVGLPAIYVPFPIGNGEQRLNALPVVNAGGGLVVADADLTPGLVARQVVRLFSD
EEEHHHHCCCCEEEEEECCCCCHHHHCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHCC
PAQLAAMTAAAARVGHRDAAHHVAKVALDLARAERDTASGRSAGGKP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNNSVREPTRGRRGSPPVADAALSVNPPLSVVLAGGGTAGHVEPAMAVADALRALDPQVR
CCCCCCCCCCCCCCCCCHHCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEE
ITALGTSRGLETRLVPERGYHLELITPVPLPRKLTGDLARLPLRVWRAVRETRAVFEVVE
EEEEECCCCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHVVVGFGGYVALPAYLAARGIPRVRRRIPVVVHEANARAGIANRVGVRTAERVLSAVPG
HEEEEECCHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
SGLRGAEVVGVPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
CCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHHC
AAEDLAASGVAVLHAYGLKNTLELRTPEYGEPPYVAVPYLDRMDLAYAAADLVICRSGAM
CHHHHHHCCCCEEEHHCCCCEEEECCCCCCCCCEEEECCCCHHHHHHHHHHEEEECCCCC
TVAEVSAVGLPAIYVPFPIGNGEQRLNALPVVNAGGGLVVADADLTPGLVARQVVRLFSD
EEEHHHHCCCCEEEEEECCCCCHHHHCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHCC
PAQLAAMTAAAARVGHRDAAHHVAKVALDLARAERDTASGRSAGGKP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA