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The map label for this gene is mraY [H]

Identifier: 221229908

GI number: 221229908

Start: 1079183

End: 1080262

Strand: Direct

Name: mraY [H]

Synonym: MLBr_00911

Alternate gene names: 221229908

Gene position: 1079183-1080262 (Clockwise)

Preceding gene: 221229907

Following gene: 221229909

Centisome position: 33.02

GC content: 59.44

Gene sequence:

>1080_bases
ATGAGACAGATCCTTGTCGCTGTCACAGTCGCGCTGGTTGTGTCTATCCTGTTGACCCCAGCGCTGATCCGGTTGTTCAC
CAGACACGGCTTCGGCCAGGAAATCCGTGAAGACGGCCCACCCAGCCACCACAACAAACGGGGAACCCCATCTATGGGTG
GTGTTGCCATTGTCGCCGGCATTTGGGCCGGCTACCTGGGCACTCATCTGGCAGGCTTGGCGTTCGATGGTGAAGGCGTA
TCGGCGTCGGGTGTGCTGGTGTTGGGTCTGGCTACTGCGCTGGGCGGCGTCGGATTCCTCGATGACTTGATCAAGATCCG
CAGGTCGCGCAACCTCGGGTTGAACAAGACAGCCAAGACCGTCGGGCAGATAACAGCCGCGGTGCTGTTCGGGGTGCTGG
TGTTGCAGTTCCGCAATGGCGCCGGCTTGACACCGGCCAGCGCGGATCTGTCCTACGTGCGTGAGATTGCGACCGTCACC
TTGGCGCCGGCGTTATTCGTGCTGTTCTGCATGGTCATCGTCAGTGCCTGGTCAAATGCGGTCAACTTCACCGACGGCTT
AGACGGGCTGGCCGCTGGCAGTATGGCGATGGTCACCGCCGCCTATGTTTTGATCACCTTTTGGCAATATCGCAATGCGT
GCGTGACGGCGCCGGGACTGGGTTGCTATAATGTGCGCGATCCGCTGGACCTGACGTTGATTGCAGCTGCGACGGTGGGC
GCGTGTATTGGCTTTTTGTGGTGGAATGCCGCACCGGCCAAGGTTTTCATGGGAGATACCGGGTCCCTAGCGTTGGGTGG
CGTGATCGCTGGCTTGTCGGTCACCAGTCGCACTGAGATTCTTGCGGTCGTGCTGGGTTCGCTGTTCGTTGCCGAAATCA
CCTCGGTTGTATTGCAGATTCTGGCTTTCCGGACCACTGGTCGTCGGGTGTTTCGGATGGCGCCGTTCCACCATCATTTC
GAATTGGCCGGTTGGGCCGAAACCACTGTGATCATTCGTTTTTGGCTGCTCACAGCGATCGCTTGCGGTCTGGGCGTGGT
CCTGTTCTATGGCGAGTGGCTAGCCACCATTGGCGCTTGA

Upstream 100 bases:

>100_bases
CTGAAGTACGACCCGGCGACGTGGTCCTGATCAAGGCGTCGCATTCGGTCGGCCTAGGAGCGCTGGCTGATGTACTGGTG
GGCGACGGGGCCATCCGCCC

Downstream 100 bases:

>100_bases
CGTGCTTGACACACTGGTACCGGGCGCGCCTGTATTAGTAGCTGGTGGCGGGGTGACCGGGCGGGCGGTACTGGCGGCGC
TGACCCGTTTTGGCATGGCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTPSMGGVAIVAGIWAGYLGTHLAGLAFDGEGV
SASGVLVLGLATALGGVGFLDDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADLSYVREIATVT
LAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVG
ACIGFLWWNAAPAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQILAFRTTGRRVFRMAPFHHHF
ELAGWAETTVIIRFWLLTAIACGLGVVLFYGEWLATIGA

Sequences:

>Translated_359_residues
MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTPSMGGVAIVAGIWAGYLGTHLAGLAFDGEGV
SASGVLVLGLATALGGVGFLDDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADLSYVREIATVT
LAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVG
ACIGFLWWNAAPAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQILAFRTTGRRVFRMAPFHHHF
ELAGWAETTVIIRFWLLTAIACGLGVVLFYGEWLATIGA
>Mature_359_residues
MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTPSMGGVAIVAGIWAGYLGTHLAGLAFDGEGV
SASGVLVLGLATALGGVGFLDDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADLSYVREIATVT
LAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVG
ACIGFLWWNAAPAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQILAFRTTGRRVFRMAPFHHHF
ELAGWAETTVIIRFWLLTAIACGLGVVLFYGEWLATIGA

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=345, Percent_Identity=35.0724637681159, Blast_Score=191, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 37760; Mature: 37760

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTPSMGGVAIVAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
IWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFLDDLIKIRRSRNLGLNKTAKT
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHH
VGQITAAVLFGVLVLQFRNGAGLTPASADLSYVREIATVTLAPALFVLFCMVIVSAWSNA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNFTDGLDGLAAGSMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHH
ACIGFLWWNAAPAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFYGEWLATIGA
HHHHHCCCHHEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTPSMGGVAIVAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
IWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFLDDLIKIRRSRNLGLNKTAKT
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHH
VGQITAAVLFGVLVLQFRNGAGLTPASADLSYVREIATVTLAPALFVLFCMVIVSAWSNA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNFTDGLDGLAAGSMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHH
ACIGFLWWNAAPAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFYGEWLATIGA
HHHHHCCCHHEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]