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The map label for this gene is trpD

Identifier: 221229883

GI number: 221229883

Start: 1047707

End: 1048807

Strand: Direct

Name: trpD

Synonym: MLBr_00883

Alternate gene names: 221229883

Gene position: 1047707-1048807 (Clockwise)

Preceding gene: 221229878

Following gene: 221229884

Centisome position: 32.06

GC content: 62.67

Gene sequence:

>1101_bases
GTGGTTTTGTCATCGCAACCACCTTCTTCTCGCAGCGCCACCGGATCGGTGTTGTCGTGGCCGCAGGTCTTGGGGCGTTT
GACAGCAGGGCAGGATCTCACGCGGGGCCAGGCTGCTTGGGCGATGGGCCAGGTCATGACTGGGAACGCACGGCCAGCCC
AGATCGCCGCGTTCGCGGTGGCGATGAAGATGAAGGTCCCCACCGCGGCCGAAGTCAGTGAGCTTGCTGACGTCATGCTC
AGCCACGCGCGTAAGCTGCCGACAGAGGCGATCTGCCAAGATATCGGAGAAACCGTAGACATTGCCGGAACCGGGGGAGA
TGGTGCCAACACAGTCAACCTGTCCACTATGGCTGCGATCGTGGTTGCGGCCGCAGGTGTACCGGTGGTCAAACATGGTA
ACCGGGCCTCGTCTTCACTGTCAGGCGGCGCTGACACTCTGGAAGCATTGGGGGTCCGTATCGACCTTGGACCAGAGCAA
GTCGCGAATAGCCTAGCCGAAATCGGGATCGGGTTCTGCTTCGCGCCGCTGTTCCAACCGTCGTACCGGTACGCGTCCGC
GGTGCGCCATGAGATCGGGGTGCCGACCGTGTTCAACATCCTCGGGCCGCTGACCAATCCGGCCTGGCCGCGGGCTGGAT
TGATCGGCTGTGCGTTTGGCAATCTTGCCGAGGTTATGGCGGGGGTGTTCGCTGCGCGACGCTCCAGTGTGCTGGTAGTG
CATGGCGATGATGGACTCGACGAATTGACCACCACTACTACCAGTACGATCTGGCGTGTTCAGGCGGGCACAGTGGATAA
GCTGACTTTTGATCCTGTCGAATTCGGGTTTGCGCGTGCTCACCTTGACGATCTGTTGGGAGGGGATGCGCAAACTAATG
CGGCGAAGGTGCGTGCGGTACTGGCCGGGGCCAAGGGCCCAGTCCGCGACGCCGTTGTGCTCAACGCCGCCGGTGCGATC
GTCGCCTACGCTGGGTTATCCAGCCACGCTGAATGGTCGCCCGCGTGGGACGATGGGTTGGCGCGCGCCAGCGCTGCCAT
CGATTCGGGTGCCGCCGAACAGCTCCTCGCGCGGTGGGTGAGGTTTAGTCAGCAGGTCTGA

Upstream 100 bases:

>100_bases
ACCCGGGGCGGCAAATCAGTTGCCTGCGTAGCTTTTGCACCGTTGGCGGCGTGCTTTGGAGGTGTTTGGGGGCGAGTGGT
TCGCATGGGACCATTGGCCG

Downstream 100 bases:

>100_bases
ATCCCACTCCCGGGAATCGGCAGCGTGCTCGGCAGGCCAGCCTGTGCCGAGTACACTGATGCCGCCCACGCTGCCCAGGT
GCCCGCTGTCTGCAGGGGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAVAMKMKVPTAAEVSELADVML
SHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQ
VANSLAEIGIGFCFAPLFQPSYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVV
HGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAVLAGAKGPVRDAVVLNAAGAI
VAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWVRFSQQV

Sequences:

>Translated_366_residues
MVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAVAMKMKVPTAAEVSELADVML
SHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQ
VANSLAEIGIGFCFAPLFQPSYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVV
HGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAVLAGAKGPVRDAVVLNAAGAI
VAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWVRFSQQV
>Mature_366_residues
MVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAVAMKMKVPTAAEVSELADVML
SHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQ
VANSLAEIGIGFCFAPLFQPSYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVV
HGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAVLAGAKGPVRDAVVLNAAGAI
VAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWVRFSQQV

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=33.4507042253521, Blast_Score=151, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320561, Length=330, Percent_Identity=29.6969696969697, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_MYCLB (B8ZQM2)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503299.1
- ProteinModelPortal:   B8ZQM2
- SMR:   B8ZQM2
- EnsemblBacteria:   EBMYCT00000087357
- GeneID:   7326135
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016787
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37708; Mature: 37708

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCHHHHHHHHH
AMKMKVPTAAEVSELADVMLSHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAI
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCEEHHHHHHHH
VVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQVANSLAEIGIGFCFAPLFQP
HHHHCCCCEEECCCCCCCCCCCCHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHCCC
SYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVV
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
HGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAV
ECCCCHHHHHHHHHHEEEEEECCCCCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LAGAKGPVRDAVVLNAAGAIVAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWV
HHCCCCCCCHHHEEECCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
RFSQQV
HHHCCC
>Mature Secondary Structure
MVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCHHHHHHHHH
AMKMKVPTAAEVSELADVMLSHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAI
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCEEHHHHHHHH
VVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQVANSLAEIGIGFCFAPLFQP
HHHHCCCCEEECCCCCCCCCCCCHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHCCC
SYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVV
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
HGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAV
ECCCCHHHHHHHHHHEEEEEECCCCCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LAGAKGPVRDAVVLNAAGAIVAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWV
HHCCCCCCCHHHEEECCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
RFSQQV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA