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The map label for this gene is cofD [H]

Identifier: 221229803

GI number: 221229803

Start: 901772

End: 902911

Strand: Reverse

Name: cofD [H]

Synonym: MLBr_00759

Alternate gene names: 221229803

Gene position: 902911-901772 (Counterclockwise)

Preceding gene: 221229805

Following gene: 221229802

Centisome position: 27.63

GC content: 61.14

Gene sequence:

>1140_bases
ATGTCGAGCGCATCTGGTCACAAGCTCTGCGCAGATCTTTTCCCGCCTTCCCTGTTCCACGGGGTGCTGTGGGTCGGGCT
CAATGCCCCGACTCTCCCCCGCAAGCAGGCGGTGAGCAGAGCGGTACTATCATGCGGTGTGAGGGTCACGGTTCTGGTCG
GTGGTGTGGGCGGTGCCCACTTCCTGCTGGGGGTTCAGCAACTGCTCGGCCTGGGTCAGTTTGGCCCTCAGCAATGCCCA
GATACCTTAACAACAGGCCACGAGCTAACTGCCGTTGTCAATATCGGCGACGACGCCTGGATTCACGGGTTGCGTGTCTG
TCCAGATCTGGACACTTGCATGTACACCCTAGGCGATGGGATCGACCCGCAGCGCGGCTGGGGTCACCGCGACGAAACCT
GGCACGCCAAGGAGGAACTCGCGCGGTACGGCGTGCAACCCGACTGGTTCGAACTCGGGGACCGCGATCTGGCCACTCAC
TTGGTACGCACCCAGATGCTGAATGCCGGCTACCGGCTGTCGCAGATCACCACTGCACTGTGTGACCGCTGGCAACCAGG
AGCACGGTTGGTGCCAGCCAGTGACGACCGCTGTGAAACCCACGTGGTGATCACTGATCCGATCAATGACAGCCGGCGCG
CAATCCACTTCCAGGAATGGTGGGTACGCTACCGCGCCCAGGTACCCACACACAGTTTCGCCTATGTTGGAGCGGAAAAA
GCCAGCGCCGCAACTGAAGCGGTAGCAGCTATCGCTGACGCCGACGTCATTTTGGTGGCACCATCGAATCCGGTGGTAAG
TATAGGCGCCATCCTGGCCATCCCCGGTATTCGCGGTGCACTTCGGACAACCACCGCTCCGGTCGTAGGCTACTCGCCAA
TCATTGATGGAAAGCCGTTGCGCGGCATGGCCGATAAATGTCTCACAGTGATCGGGGTACAATCCACAGCAACGGCAGTG
GGCCAGCATTATGGAGCGCGCCGCACCACCGGGATTCTGGACTGCTGGCTGGTACACGAAGACGACCACGCTGAAATCGA
GGGGGTCGCGGTGCGGTCGATACCGCTGCTGATGAGCAGCCCGAAGACAACGGCTGACATGGTTAACATCGGGCTTCAGC
TCGCGGGCGTGTCGGCGTGA

Upstream 100 bases:

>100_bases
TGATTAGACACGGGTTGACCTGCCGGGTCAAGCGTGACTGCGAATTTCCATACCATGTTGTGATCGAATTTCGGCGTTTC
TGTTGCCGTCAGCCCTCGGC

Downstream 100 bases:

>100_bases
CCAGTTCGGATTCGCACCGCTCTGCACCGTCGCCTGAGCATGGCACCGCCTCGACGATCGAGATCCTTCCTGTCGCCGGG
CTTCCCGAATTCCGTCCCGG

Product: LPPG:FO 2-phospho-L-lactate transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVTVLVGGVGGAHFLLGVQQLLGLGQFGPQQCP
DTLTTGHELTAVVNIGDDAWIHGLRVCPDLDTCMYTLGDGIDPQRGWGHRDETWHAKEELARYGVQPDWFELGDRDLATH
LVRTQMLNAGYRLSQITTALCDRWQPGARLVPASDDRCETHVVITDPINDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEK
ASAATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYSPIIDGKPLRGMADKCLTVIGVQSTATAV
GQHYGARRTTGILDCWLVHEDDHAEIEGVAVRSIPLLMSSPKTTADMVNIGLQLAGVSA

Sequences:

>Translated_379_residues
MSSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVTVLVGGVGGAHFLLGVQQLLGLGQFGPQQCP
DTLTTGHELTAVVNIGDDAWIHGLRVCPDLDTCMYTLGDGIDPQRGWGHRDETWHAKEELARYGVQPDWFELGDRDLATH
LVRTQMLNAGYRLSQITTALCDRWQPGARLVPASDDRCETHVVITDPINDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEK
ASAATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYSPIIDGKPLRGMADKCLTVIGVQSTATAV
GQHYGARRTTGILDCWLVHEDDHAEIEGVAVRSIPLLMSSPKTTADMVNIGLQLAGVSA
>Mature_378_residues
SSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVTVLVGGVGGAHFLLGVQQLLGLGQFGPQQCPD
TLTTGHELTAVVNIGDDAWIHGLRVCPDLDTCMYTLGDGIDPQRGWGHRDETWHAKEELARYGVQPDWFELGDRDLATHL
VRTQMLNAGYRLSQITTALCDRWQPGARLVPASDDRCETHVVITDPINDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEKA
SAATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYSPIIDGKPLRGMADKCLTVIGVQSTATAVG
QHYGARRTTGILDCWLVHEDDHAEIEGVAVRSIPLLMSSPKTTADMVNIGLQLAGVSA

Specific function: Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F42

COG id: COG0391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002882
- InterPro:   IPR010115 [H]

Pfam domain/function: PF01933 UPF0052 [H]

EC number: NA

Molecular weight: Translated: 40621; Mature: 40490

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVTVLVGGVGGAH
CCCCCCCHHHHHHCCHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHH
FLLGVQQLLGLGQFGPQQCPDTLTTGHELTAVVNIGDDAWIHGLRVCPDLDTCMYTLGDG
HHHHHHHHHCCCCCCHHCCCHHHCCCCEEEEEEECCCCHHHCCEECCCCHHHHHHHHCCC
IDPQRGWGHRDETWHAKEELARYGVQPDWFELGDRDLATHLVRTQMLNAGYRLSQITTAL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
CDRWQPGARLVPASDDRCETHVVITDPINDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEK
HHCCCCCCEEECCCCCCCEEEEEEECCCCCCHHEEHHHHHHHHHHHCCCCCCEEEECCHH
ASAATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYSPIIDGKPL
HHHHHHHHHHHCCCCEEEEECCCCCEEHHHHEECCCCCCHHHHCCCCCCCCCCCCCCCCC
RGMADKCLTVIGVQSTATAVGQHYGARRTTGILDCWLVHEDDHAEIEGVAVRSIPLLMSS
CCHHHHHHHHEECCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEEEEECC
PKTTADMVNIGLQLAGVSA
CCCHHHHHHHCEEEEECCC
>Mature Secondary Structure 
SSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVTVLVGGVGGAH
CCCCCCHHHHHHCCHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHH
FLLGVQQLLGLGQFGPQQCPDTLTTGHELTAVVNIGDDAWIHGLRVCPDLDTCMYTLGDG
HHHHHHHHHCCCCCCHHCCCHHHCCCCEEEEEEECCCCHHHCCEECCCCHHHHHHHHCCC
IDPQRGWGHRDETWHAKEELARYGVQPDWFELGDRDLATHLVRTQMLNAGYRLSQITTAL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
CDRWQPGARLVPASDDRCETHVVITDPINDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEK
HHCCCCCCEEECCCCCCCEEEEEEECCCCCCHHEEHHHHHHHHHHHCCCCCCEEEECCHH
ASAATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYSPIIDGKPL
HHHHHHHHHHHCCCCEEEEECCCCCEEHHHHEECCCCCCHHHHCCCCCCCCCCCCCCCCC
RGMADKCLTVIGVQSTATAVGQHYGARRTTGILDCWLVHEDDHAEIEGVAVRSIPLLMSS
CCHHHHHHHHEECCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEEEEECC
PKTTADMVNIGLQLAGVSA
CCCHHHHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]