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The map label for this gene is glpD [H]

Identifier: 221229779

GI number: 221229779

Start: 851957

End: 853714

Strand: Direct

Name: glpD [H]

Synonym: MLBr_00713

Alternate gene names: 221229779

Gene position: 851957-853714 (Clockwise)

Preceding gene: 221229774

Following gene: 221229780

Centisome position: 26.07

GC content: 62.23

Gene sequence:

>1758_bases
GTGACTGATCTGATCCAAGCACCGGAGAGCGAGCAGACATGGCCGGCTTCTGCGTTGGGACCGCAGCAACGTGCGGCGGC
CTGGGAGCGGTTTGGCACTGAGCAGTTCGACGTGGTGGTCATTGGTGGCGGCGTAGTGGGGTCCGGGTGTGCGCTGGATG
CTGCCACGCGCGGCCTCAAAGTGGCGTTGGTCGAGGCGCGGGACTTGGCTTCGGGTACGTCGAGCCGCTCGTCGAAGATG
TTTCACGGGGGGTTGCGTTACCTTGAGCAACTCGAGTTCGGGTTGGTGCGTGAGGCGCTCTATGAGCGTGAGTTGTCGTT
GACCACGTTGGCACCGCATCTGGTCAAACCGTTGCCGTTCCTGTTTCCGCTAACCAAACGTTGGTGGGAACGCCCGTACA
TAGCTGCCGGCATCTTCCTGTATGATCGCCTTGGTGGCGCTAAATCGGTTCCGGCGCAAAAGCATTTGACTCGTGCCGGT
GCGTTGCGATTAAGTCCGGGCCTAAAACGCAGCTCCTTGATCGGTGGTATTCGCTACTACGACACCGTCGTCGACGACGC
CCGGCACACCTTGACTGTAGCGCGCACCGCTGCGCATTACGGAGCGGTCGTGCGATGCTCCACCCAGGTGGTCGCATTGC
TGCGCGAGGGCGACCGAGTGATCGGCGTGCGGGTTCGCGATTCGGAGGATGGCGCGGTTACTGAGATCCGCGGCCACGTT
GTGGTCAACGCTACTGGGGTCTGGACCGACGAAATTCAGGCGTTGTCCAAGCAGCGTGGACGATTCCAGGTGCGCGTGTC
CAAGGGTGTGCACGTAGTGGTACCGCGGGACCGGATCGTCAGTGACGTCGCGATGATCCTGCGCACCAAGAAGTCGGTGA
TGTTCATCATCCCGTGGGGTAACCACTGGATCATCGGAACGACCGATACTGATTGGAATCTCGACCTGGCCCATCCCGCG
GCCACCAAGGCGGATATTGACTACATCCTGCAGACGGTCAATACTGTGTTGGCTACCCCGTTGACCCACGCCGACATCGA
TGGGGTGTATGCTGGGCTACGCCCGCTCCTCGCCGGGGAAAGTGATGACACTTCCAAGTTGACCCGTGAACACGCGGTCG
CGGTGCCGGTGGCGGGTCTGGTCGCGATCGCCGGCGGCAAGTACACCACGTACCGGGTGATGGCCGCCGACGCGATTGAC
GCCGCGGTTGCATTCGTTCCGGCCCGGGTAGCTCCGTCGATCACCGAGAAAGTAGGTTTGCTGGGCGCCGACGGTTACTT
TGCGTTGATCAATCAGGTCGAACACGTCGCCGCGTTGCAAGGTCTGCACCCCTACCGGGTGCGTCATCTGCTGGACCGCT
ACGGCGCGCTTATCGGTGACGTCTTGGCCTTGGCGGCTGAAGCACCCGACCTGCTCAGTCCGATTCAGGAAGCTCCGGGC
TATTTGAAGGTGGAAGCCCGCTACGCTGTAACCGCCGAGGGCGCCTTGCATCTCGAGGACATCTTGGCCCGCCGGATGAG
AGTCTCTATCGAATATCCACACCGCGGCGTCGCCTGTGCCCGGGAGGTGGCCGATGTGGTCGCTCCGGTGTTGGGTTGGA
CGGCCGAGGATATCGATCGCGAGGTGGCGACTTATAATGCGCGGGTGGAGGCCGAGGTACTGTCGCAGGCCCAGCCCGAC
GACGTGTCGGCGGACATGTTGCGAGCCAGCGCACCCGAGGCGCGCACCAAGATCATCGAACCGGTGTCGCTAACTTGA

Upstream 100 bases:

>100_bases
TCTGGACTAAGGCCGATCTTTGGTCGACTGACGAACTAGCCTTGGTGGCACACTAATTTAACTTTAACTTACCGACGAAT
AACCGAGGAGTCCTGGTGTC

Downstream 100 bases:

>100_bases
GCGGACAGTTAAGTGTCGCGGGGACCCGCGCGAAAGTGCTGAATGGAGAAGTCGTCTATTCGGACGGTGAGGCTACCGTG
GTGCCCAGCGGGGCTAGTGT

Product: putative glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MTDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKM
FHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQKHLTRAG
ALRLSPGLKRSSLIGGIRYYDTVVDDARHTLTVARTAAHYGAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHV
VVNATGVWTDEIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWGNHWIIGTTDTDWNLDLAHPA
ATKADIDYILQTVNTVLATPLTHADIDGVYAGLRPLLAGESDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAID
AAVAFVPARVAPSITEKVGLLGADGYFALINQVEHVAALQGLHPYRVRHLLDRYGALIGDVLALAAEAPDLLSPIQEAPG
YLKVEARYAVTAEGALHLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDREVATYNARVEAEVLSQAQPD
DVSADMLRASAPEARTKIIEPVSLT

Sequences:

>Translated_585_residues
MTDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKM
FHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQKHLTRAG
ALRLSPGLKRSSLIGGIRYYDTVVDDARHTLTVARTAAHYGAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHV
VVNATGVWTDEIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWGNHWIIGTTDTDWNLDLAHPA
ATKADIDYILQTVNTVLATPLTHADIDGVYAGLRPLLAGESDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAID
AAVAFVPARVAPSITEKVGLLGADGYFALINQVEHVAALQGLHPYRVRHLLDRYGALIGDVLALAAEAPDLLSPIQEAPG
YLKVEARYAVTAEGALHLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDREVATYNARVEAEVLSQAQPD
DVSADMLRASAPEARTKIIEPVSLT
>Mature_584_residues
TDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKMF
HGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQKHLTRAGA
LRLSPGLKRSSLIGGIRYYDTVVDDARHTLTVARTAAHYGAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHVV
VNATGVWTDEIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWGNHWIIGTTDTDWNLDLAHPAA
TKADIDYILQTVNTVLATPLTHADIDGVYAGLRPLLAGESDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAIDA
AVAFVPARVAPSITEKVGLLGADGYFALINQVEHVAALQGLHPYRVRHLLDRYGALIGDVLALAAEAPDLLSPIQEAPGY
LKVEARYAVTAEGALHLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDREVATYNARVEAEVLSQAQPDD
VSADMLRASAPEARTKIIEPVSLT

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=521, Percent_Identity=36.084452975048, Blast_Score=296, Evalue=5e-80,
Organism=Homo sapiens, GI285002231, Length=521, Percent_Identity=36.084452975048, Blast_Score=296, Evalue=5e-80,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=32.9059829059829, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1788574, Length=380, Percent_Identity=30, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17509253, Length=561, Percent_Identity=33.8680926916221, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI115534726, Length=507, Percent_Identity=34.3195266272189, Blast_Score=235, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6322036, Length=474, Percent_Identity=35.8649789029536, Blast_Score=220, Evalue=6e-58,
Organism=Drosophila melanogaster, GI161077125, Length=540, Percent_Identity=36.4814814814815, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24653942, Length=540, Percent_Identity=36.4814814814815, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24653944, Length=540, Percent_Identity=36.4814814814815, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI20130025, Length=540, Percent_Identity=36.4814814814815, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24586295, Length=545, Percent_Identity=33.394495412844, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI19921278, Length=544, Percent_Identity=29.4117647058824, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI45550977, Length=366, Percent_Identity=27.3224043715847, Blast_Score=122, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 63373; Mature: 63242

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGCALDAATRGLK
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCEECCCCCHHHHCCCEE
VALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPF
EEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHH
LFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQKHLTRAGALRLSPGLKRSSLIGGIRYY
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHCCHHHH
DTVVDDARHTLTVARTAAHYGAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHV
HHHHHCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECEE
VVNATGVWTDEIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWG
EEEECCCCHHHHHHHHHCCCEEEEEEECCEEEEECCHHHHHHHHHHHHCCCCEEEEEECC
NHWIIGTTDTDWNLDLAHPAATKADIDYILQTVNTVLATPLTHADIDGVYAGLRPLLAGE
CEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
SDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAIDAAVAFVPARVAPSITEKVGL
CCCHHHHHHHHHHHCCHHHHHEECCCCEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHCC
LGADGYFALINQVEHVAALQGLHPYRVRHLLDRYGALIGDVLALAAEAPDLLSPIQEAPG
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
YLKVEARYAVTAEGALHLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDR
EEEEEEEEEEEECCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
EVATYNARVEAEVLSQAQPDDVSADMLRASAPEARTKIIEPVSLT
HHHHHCCEEHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGCALDAATRGLK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCEECCCCCHHHHCCCEE
VALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPF
EEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHH
LFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQKHLTRAGALRLSPGLKRSSLIGGIRYY
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHCCHHHH
DTVVDDARHTLTVARTAAHYGAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHV
HHHHHCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECEE
VVNATGVWTDEIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWG
EEEECCCCHHHHHHHHHCCCEEEEEEECCEEEEECCHHHHHHHHHHHHCCCCEEEEEECC
NHWIIGTTDTDWNLDLAHPAATKADIDYILQTVNTVLATPLTHADIDGVYAGLRPLLAGE
CEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
SDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAIDAAVAFVPARVAPSITEKVGL
CCCHHHHHHHHHHHCCHHHHHEECCCCEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHCC
LGADGYFALINQVEHVAALQGLHPYRVRHLLDRYGALIGDVLALAAEAPDLLSPIQEAPG
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
YLKVEARYAVTAEGALHLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDR
EEEEEEEEEEEECCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
EVATYNARVEAEVLSQAQPDDVSADMLRASAPEARTKIIEPVSLT
HHHHHCCEEHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]