Click here to switch to the map view.

The map label for this gene is pmmB [C]

Identifier: 221229776

GI number: 221229776

Start: 843856

End: 845472

Strand: Reverse

Name: pmmB [C]

Synonym: MLBr_00706

Alternate gene names: 221229776

Gene position: 845472-843856 (Counterclockwise)

Preceding gene: 221229777

Following gene: 221229775

Centisome position: 25.87

GC content: 64.07

Gene sequence:

>1617_bases
TTGAAGGCTGCCGTGACACCCGAAGAGTGGATCACGCACGATCCCGACCCACAGACAGCCGCCGAGCTGGCCGCGTGCGA
CCCCGATGAACTTGCGGCGCGGTTCACCCGTGCACTGCGCTTCGGCACGTCGGGCTTGCGCGGACCAGTGCGCGGCGGCC
CCGACGCCATGAACCTAGCGGTGGTGTTGCGAGCGACCTGGGCCGTGGCACAGGTGCTCCTGCAACGAGCGGGCTCGCGG
CCTGCAACCGTAATCGTCGGGCGCGACTCTCGGCACGGCTCGGCGGCATTCGTCGCTGCGACCGCTGAGGTGCTTGCCGC
TGAAGGTTTTTCCGTTCTGCTGCTACCCAATCCGGCACCCACGCCGGTGGTGGCGTTTGCGGTGCGCAATACCGGCGCCG
CGGCCGGGATCCAGATCACAGCATCGCACAACCCGCCGACCGATAACGGGTACAAGGTGTATTTCGACGGCGGCATCCAG
ATCATCTCTCCCATTGACCACCAAATCGAAAACGCGATGGCCGCTGCTCCCCTGGCCGACCAGATCACCAGGAAACCCGT
AAACCCCAGTGAAAACAGCGCCTCCGATCTGGTTGACCATTATATTCAGCGAGCGGCCGCGGTACGGCGCTCCAACGGTT
CAGTTCGGGTTGCCCTTACACCGATGCACGGAGTGGGCGGTGCGGTAGCCGTCGAGACGCTGCGGCGCACCGGCTTTGAC
GACGTGCACACCGTAGCGGCGCAGTTCGAGCCCGACCCCGACTTTCCAACCGTCGCGTTCCCAAACCCGGAGGAGCCCGG
CGCCACCGACGCATTGCTGGCCCTGGCCGCCCATGTCGGGGCCGACGTCGCGATAGCACTGGACCCCGACGCCGACCGCT
GCGCCGTTGGTATACCCACCAACTCGGGATGGCGGATGCTGTCCGGAGACGAAACCGGTTGGCTGCTAGGCGATTACATT
TTGTCGCAAACCGACAAGCCGGAAACCGCCGTGGTAGCCAGTACCGTGGTGTCGTCGCGTATGTTGCCAGCAATCGCCAC
ACACTACAACGCGGTCCACGTCGAGACCCTCACCGGCTTCAAGTGGCTGGCGCGCGCCGACGCAAACCTGCCGGGCACTC
TTGTGTACGCCTATGAGGAAGCTATCGGGCATTGTGTCGACCCCACTGCCGTACGCGACAAAGACGGCATCAGCGCCGCG
GTGTTAGTGTGCGATCTGGTTGCCGCACTGCACAAGCAGGGCCGCTCGGTGCCCGACATGCTTGACCAACTCGCCCTACG
CCACGGCGTGCACGACGTTACAGCAATATCACGTCGCATTGGCCCCAAACAAACGGGAGTTGACGAGGCTGTCGACCTGA
TTCAGCGGCTACGCGCAGCCCCGCCGAGTCAGCTGGCCGGGTTCACCGCGACCACTACCGATATCACCGACGCGCTAATC
TTCACCGGCGGTGATGATGACACGTGGGTCCGGGTAGTGGTGCGGCTATCAGGAACCGAACCGAAGTTAAAGTGCTACTT
GGAAGTTCGCTGCTCGGTGGCTGGCAACCTACCATCCACCCGACAACGGGCCAGGGTGCTGCGCGACGAGCTAGTCACCT
TGGTGCAGCAGTGGTGA

Upstream 100 bases:

>100_bases
GGATCACCGGCAAGCCACTTAACCATGCTGAGGTGCTTGCCGCGGGGACTGCGTCAGCGAACCGGATCGGGTCCCTGCTG
GCCGACATCATAGCCCGGTT

Downstream 100 bases:

>100_bases
TTCTCAGGTGAGTCAGCGGGGCCCAAATTGGCAGTCGCTGGCGTCACCGAAACCCGGCACAATCACAATATAGTGATTGC
TTCGTTGAGTCCCTTGTCAA

Product: putative phospho-sugar mutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKAAVTPEEWITHDPDPQTAAELAACDPDELAARFTRALRFGTSGLRGPVRGGPDAMNLAVVLRATWAVAQVLLQRAGSR
PATVIVGRDSRHGSAAFVAATAEVLAAEGFSVLLLPNPAPTPVVAFAVRNTGAAAGIQITASHNPPTDNGYKVYFDGGIQ
IISPIDHQIENAMAAAPLADQITRKPVNPSENSASDLVDHYIQRAAAVRRSNGSVRVALTPMHGVGGAVAVETLRRTGFD
DVHTVAAQFEPDPDFPTVAFPNPEEPGATDALLALAAHVGADVAIALDPDADRCAVGIPTNSGWRMLSGDETGWLLGDYI
LSQTDKPETAVVASTVVSSRMLPAIATHYNAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAA
VLVCDLVAALHKQGRSVPDMLDQLALRHGVHDVTAISRRIGPKQTGVDEAVDLIQRLRAAPPSQLAGFTATTTDITDALI
FTGGDDDTWVRVVVRLSGTEPKLKCYLEVRCSVAGNLPSTRQRARVLRDELVTLVQQW

Sequences:

>Translated_538_residues
MKAAVTPEEWITHDPDPQTAAELAACDPDELAARFTRALRFGTSGLRGPVRGGPDAMNLAVVLRATWAVAQVLLQRAGSR
PATVIVGRDSRHGSAAFVAATAEVLAAEGFSVLLLPNPAPTPVVAFAVRNTGAAAGIQITASHNPPTDNGYKVYFDGGIQ
IISPIDHQIENAMAAAPLADQITRKPVNPSENSASDLVDHYIQRAAAVRRSNGSVRVALTPMHGVGGAVAVETLRRTGFD
DVHTVAAQFEPDPDFPTVAFPNPEEPGATDALLALAAHVGADVAIALDPDADRCAVGIPTNSGWRMLSGDETGWLLGDYI
LSQTDKPETAVVASTVVSSRMLPAIATHYNAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAA
VLVCDLVAALHKQGRSVPDMLDQLALRHGVHDVTAISRRIGPKQTGVDEAVDLIQRLRAAPPSQLAGFTATTTDITDALI
FTGGDDDTWVRVVVRLSGTEPKLKCYLEVRCSVAGNLPSTRQRARVLRDELVTLVQQW
>Mature_538_residues
MKAAVTPEEWITHDPDPQTAAELAACDPDELAARFTRALRFGTSGLRGPVRGGPDAMNLAVVLRATWAVAQVLLQRAGSR
PATVIVGRDSRHGSAAFVAATAEVLAAEGFSVLLLPNPAPTPVVAFAVRNTGAAAGIQITASHNPPTDNGYKVYFDGGIQ
IISPIDHQIENAMAAAPLADQITRKPVNPSENSASDLVDHYIQRAAAVRRSNGSVRVALTPMHGVGGAVAVETLRRTGFD
DVHTVAAQFEPDPDFPTVAFPNPEEPGATDALLALAAHVGADVAIALDPDADRCAVGIPTNSGWRMLSGDETGWLLGDYI
LSQTDKPETAVVASTVVSSRMLPAIATHYNAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAA
VLVCDLVAALHKQGRSVPDMLDQLALRHGVHDVTAISRRIGPKQTGVDEAVDLIQRLRAAPPSQLAGFTATTTDITDALI
FTGGDDDTWVRVVVRLSGTEPKLKCYLEVRCSVAGNLPSTRQRARVLRDELVTLVQQW

Specific function: Unknown

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=588, Percent_Identity=31.8027210884354, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI31377548, Length=559, Percent_Identity=29.695885509839, Blast_Score=199, Evalue=4e-51,
Organism=Escherichia coli, GI1789566, Length=477, Percent_Identity=26.8343815513627, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786904, Length=537, Percent_Identity=25.512104283054, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=25.164113785558, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71993870, Length=553, Percent_Identity=31.4647377938517, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71993878, Length=304, Percent_Identity=33.2236842105263, Blast_Score=153, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323934, Length=590, Percent_Identity=32.3728813559322, Blast_Score=235, Evalue=1e-62,
Organism=Drosophila melanogaster, GI20129809, Length=564, Percent_Identity=30.1418439716312, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24651977, Length=490, Percent_Identity=31.8367346938775, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24653722, Length=467, Percent_Identity=29.5503211991435, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 56998; Mature: 56998

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVTPEEWITHDPDPQTAAELAACDPDELAARFTRALRFGTSGLRGPVRGGPDAMNLA
CCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
VVLRATWAVAQVLLQRAGSRPATVIVGRDSRHGSAAFVAATAEVLAAEGFSVLLLPNPAP
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCC
TPVVAFAVRNTGAAAGIQITASHNPPTDNGYKVYFDGGIQIISPIDHQIENAMAAAPLAD
CCEEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHCCHHH
QITRKPVNPSENSASDLVDHYIQRAAAVRRSNGSVRVALTPMHGVGGAVAVETLRRTGFD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
DVHTVAAQFEPDPDFPTVAFPNPEEPGATDALLALAAHVGADVAIALDPDADRCAVGIPT
HHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCC
NSGWRMLSGDETGWLLGDYILSQTDKPETAVVASTVVSSRMLPAIATHYNAVHVETLTGF
CCCCEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCH
KWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAVLVCDLVAALHKQGRSVPDM
HHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LDQLALRHGVHDVTAISRRIGPKQTGVDEAVDLIQRLRAAPPSQLAGFTATTTDITDALI
HHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEECCCCCCEEE
FTGGDDDTWVRVVVRLSGTEPKLKCYLEVRCSVAGNLPSTRQRARVLRDELVTLVQQW
EECCCCCCEEEEEEEECCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAAVTPEEWITHDPDPQTAAELAACDPDELAARFTRALRFGTSGLRGPVRGGPDAMNLA
CCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
VVLRATWAVAQVLLQRAGSRPATVIVGRDSRHGSAAFVAATAEVLAAEGFSVLLLPNPAP
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCC
TPVVAFAVRNTGAAAGIQITASHNPPTDNGYKVYFDGGIQIISPIDHQIENAMAAAPLAD
CCEEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHCCHHH
QITRKPVNPSENSASDLVDHYIQRAAAVRRSNGSVRVALTPMHGVGGAVAVETLRRTGFD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
DVHTVAAQFEPDPDFPTVAFPNPEEPGATDALLALAAHVGADVAIALDPDADRCAVGIPT
HHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCC
NSGWRMLSGDETGWLLGDYILSQTDKPETAVVASTVVSSRMLPAIATHYNAVHVETLTGF
CCCCEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCH
KWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAVLVCDLVAALHKQGRSVPDM
HHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LDQLALRHGVHDVTAISRRIGPKQTGVDEAVDLIQRLRAAPPSQLAGFTATTTDITDALI
HHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEECCCCCCEEE
FTGGDDDTWVRVVVRLSGTEPKLKCYLEVRCSVAGNLPSTRQRARVLRDELVTLVQQW
EECCCCCCEEEEEEEECCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]