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The map label for this gene is 221229727

Identifier: 221229727

GI number: 221229727

Start: 739221

End: 740060

Strand: Direct

Name: 221229727

Synonym: MLBr_00607

Alternate gene names: NA

Gene position: 739221-740060 (Clockwise)

Preceding gene: 221229726

Following gene: 221229728

Centisome position: 22.62

GC content: 58.33

Gene sequence:

>840_bases
ATGTGGCGGATGCGGGTGGTGCACAGCACCGGATACGTGTACGAATCGCCGGCGACCGCCTCCTTCAACGAAGCCCGGCT
GACGCCGCGATCTAATACACGGCAAACCGTCATCCTCAATCGTGTCGAAACCATTCCGGCCACTCGGTCCTATCGCTACA
TCGATTATTGGGGTACCGTGGTGACAGCGTTTGACTTGCGCGCGCCGCACACCGAGCTGACAGTGACGTCTTCGTCGGTT
GTCGAGACTGAAAGCCTTGAACCATCGGTGAGCCGGATCACCTGGACTGAACTGCAGTCGATGGCCGTAATAGACCGATT
TGACGAAGTTTTGCAGCCCACCGCATACACCCCGGTAAACACTCGTGTAGCGGCCGTCGGCAAGCGGATCGCCAAGAATC
ACGAACCTCGGAAAGCCGTCGTCGCCGCAGCCCGGTGGGCGCGAAGTAAGCTGGACTACATTCCAGGCACTACCGGTGTG
CATTCGTCCGGTTTGGACGCACTGCACCAGTGTAGGGGAGTCTGTCAGGACTTCGCGCATCTGACGTTGATTGTGTTGCG
CAGCATGGGAATTCCCGGTCGCTATGTGTCAGGGTATCTGCACCCCAAACGCGACGCGGTCGTCGGAAAGACGGTTGAAG
GACGCAGTCACGCCTGGATTCAGGCCTGGACGGGTGGGTGGTGGAATTACGATCCCACCAATGACGTTGAAATCACCGAA
CAATACATCAGCGTAGGTGTGGGGCGCGATTACACAGACGTGGCCCCGTTGAAGGGAATCTACTCTGGTCGGGGGGCAAC
CGACCTTGACGTGGTTGTGGAGATCACTCGGTTGGCTTAG

Upstream 100 bases:

>100_bases
GAGACGCATTGGTGTTGCAGTATTTTCACGTCGCGCCGTGGGTAGCGTGGTCGGATGCCGGCCACCGGGGACGAATGGTT
GGCAAGCGGGGAGAAGCCTG

Downstream 100 bases:

>100_bases
TCGCATGAATGATTGGTCGGCGCAAAGAATCAACAGTGCTGGTATAACCAAGGCGCTGCGGAGTCGACTTATGCCCGGTC
GGGGACTGGCCTGCATGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MWRMRVVHSTGYVYESPATASFNEARLTPRSNTRQTVILNRVETIPATRSYRYIDYWGTVVTAFDLRAPHTELTVTSSSV
VETESLEPSVSRITWTELQSMAVIDRFDEVLQPTAYTPVNTRVAAVGKRIAKNHEPRKAVVAAARWARSKLDYIPGTTGV
HSSGLDALHQCRGVCQDFAHLTLIVLRSMGIPGRYVSGYLHPKRDAVVGKTVEGRSHAWIQAWTGGWWNYDPTNDVEITE
QYISVGVGRDYTDVAPLKGIYSGRGATDLDVVVEITRLA

Sequences:

>Translated_279_residues
MWRMRVVHSTGYVYESPATASFNEARLTPRSNTRQTVILNRVETIPATRSYRYIDYWGTVVTAFDLRAPHTELTVTSSSV
VETESLEPSVSRITWTELQSMAVIDRFDEVLQPTAYTPVNTRVAAVGKRIAKNHEPRKAVVAAARWARSKLDYIPGTTGV
HSSGLDALHQCRGVCQDFAHLTLIVLRSMGIPGRYVSGYLHPKRDAVVGKTVEGRSHAWIQAWTGGWWNYDPTNDVEITE
QYISVGVGRDYTDVAPLKGIYSGRGATDLDVVVEITRLA
>Mature_279_residues
MWRMRVVHSTGYVYESPATASFNEARLTPRSNTRQTVILNRVETIPATRSYRYIDYWGTVVTAFDLRAPHTELTVTSSSV
VETESLEPSVSRITWTELQSMAVIDRFDEVLQPTAYTPVNTRVAAVGKRIAKNHEPRKAVVAAARWARSKLDYIPGTTGV
HSSGLDALHQCRGVCQDFAHLTLIVLRSMGIPGRYVSGYLHPKRDAVVGKTVEGRSHAWIQAWTGGWWNYDPTNDVEITE
QYISVGVGRDYTDVAPLKGIYSGRGATDLDVVVEITRLA

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2569c

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y607_MYCLE (Q49757)

Other databases:

- EMBL:   U00016
- EMBL:   Z99125
- EMBL:   AL583919
- PIR:   S72594
- RefSeq:   NP_301512.1
- ProteinModelPortal:   Q49757
- EnsemblBacteria:   EBMYCT00000028990
- GeneID:   909393
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0607
- NMPDR:   fig|272631.1.peg.384
- Leproma:   ML0607
- GeneTree:   EBGT00050000015447
- HOGENOM:   HBG553889
- OMA:   FEYTDFY
- ProtClustDB:   CLSK791832
- BioCyc:   MLEP272631:ML0607-MONOMER
- InterPro:   IPR013589
- InterPro:   IPR002931
- SMART:   SM00460

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core

EC number: NA

Molecular weight: Translated: 31111; Mature: 31111

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRMRVVHSTGYVYESPATASFNEARLTPRSNTRQTVILNRVETIPATRSYRYIDYWGTV
CCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEEHHHE
VTAFDLRAPHTELTVTSSSVVETESLEPSVSRITWTELQSMAVIDRFDEVLQPTAYTPVN
EEEEECCCCCCEEEEECCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TRVAAVGKRIAKNHEPRKAVVAAARWARSKLDYIPGTTGVHSSGLDALHQCRGVCQDFAH
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTLIVLRSMGIPGRYVSGYLHPKRDAVVGKTVEGRSHAWIQAWTGGWWNYDPTNDVEITE
HHHHHHHHCCCCCHHHHCCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
QYISVGVGRDYTDVAPLKGIYSGRGATDLDVVVEITRLA
HHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHEEEEECCC
>Mature Secondary Structure
MWRMRVVHSTGYVYESPATASFNEARLTPRSNTRQTVILNRVETIPATRSYRYIDYWGTV
CCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEEHHHE
VTAFDLRAPHTELTVTSSSVVETESLEPSVSRITWTELQSMAVIDRFDEVLQPTAYTPVN
EEEEECCCCCCEEEEECCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TRVAAVGKRIAKNHEPRKAVVAAARWARSKLDYIPGTTGVHSSGLDALHQCRGVCQDFAH
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTLIVLRSMGIPGRYVSGYLHPKRDAVVGKTVEGRSHAWIQAWTGGWWNYDPTNDVEITE
HHHHHHHHCCCCCHHHHCCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
QYISVGVGRDYTDVAPLKGIYSGRGATDLDVVVEITRLA
HHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002