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The map label for this gene is yeaZ [C]

Identifier: 221229585

GI number: 221229585

Start: 470773

End: 471852

Strand: Direct

Name: yeaZ [C]

Synonym: MLBr_00378

Alternate gene names: 221229585

Gene position: 470773-471852 (Clockwise)

Preceding gene: 221229584

Following gene: 221229586

Centisome position: 14.41

GC content: 62.87

Gene sequence:

>1080_bases
ATGAGTATTGTCCTCGCCATCGACACCGCCACCGCGGCGGTGACGGCCGGCATCGTGGCATTCGATGGTCACGACTGTTT
TACGCTCGCCGAGCGGGTCACCGTCGACGCCAAGGCGCATGTTGAACGCCTCACGCCGAACGTGTTGGTCGCTCTCGCTG
ATGCCGAGTTGGCAATGTGTGAGCTCGACGCCGTGGTGGTGGGCTGTGGTCCTGGTCCGTTTACCGGTCTGCGCGTTGGC
ATGGCAACTGCTGCTGCTTACGGGCATGCGCTGGGCATTCCGGTGCATGGTGTGTGCAGTCTGGACGCTATTGGTGTGCG
AACCACCGGCGATACGCTAGTGGTTACTGATGCGCGCCGCCACGAGGTTTATTGGGCCCGTTATCGAGACGGAGTTCGCA
TCGCCGGTCCTGCCGTCGGCTCTCCCACCGATGTCGATCCCGGCACCGCGCTGACGGTGGCCGGCTCGCCTGAGCACGCG
GCGCTGTTCGGCCTGCCACTGTGCGAACCGATCTACCCGACGCCGGCTGGCTTGGTAGCCGCAGTGCCTGACTGGTCGGT
GTCCCCGATCCCACTGGTAGCGTTGTATTTGCGTCGGCCGGATGCCAAGCCAATTACTGCCGACAACGAGCCCATAGTCA
TCGGTACGTTGACACCCGCCGACGTCGATCGGTGTGCCCAGCTGGAAAGCCAGTTCTTCGACGGCGACAACCCATGGCCG
GCTGCAGCGTTCGACCGCGAACTGGCCAACTCATATAACTGTTACGTGGGTGCACGCACTGCTGACACGCTCGTCGGTTA
TGCTGGCATCACCCGCTTGGGCCACACCCCTCCATTCGAATACGAAGTGCACACCATCGCTGTAGATCCGGCATACCGAG
GGCGCGGTGTCGGCCGCCGACTGCTGGGTGAGCTGCTGGATTTCGCCGGTAGTGGTGCGATCTACCTGGAGGTCCGCACC
GACAACGAGACCGCCATTGCGTTATACCGCAGTGTGGGATTCGAACGGATCGGTCTACGCCCCCGCTACTACCCAGCCAG
CGGTGCCGATGCTTACCTCATGCGAAGGGAGGCGCAATGA

Upstream 100 bases:

>100_bases
AATGTCTAGCTGCGCGACACCTCGACATTCGTCTCGAACGAGTCAGATACTCCGATGTGCGTATCGCTACCTGGCAGTGG
GTGTGTTCCCGGGACCGTCC

Downstream 100 bases:

>100_bases
CGATCTCTGCTGTGCCCGGCACGATTATCTTGGCCATCGAAACCTCTTGCGATGAAACCGGTGTTGGTATTGCCTGCCTC
GATGACTATGGCACCGTGAC

Product: putative acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVG
MATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHA
ALFGLPLCEPIYPTPAGLVAAVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWP
AAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRRLLGELLDFAGSGAIYLEVRT
DNETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ

Sequences:

>Translated_359_residues
MSIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVG
MATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHA
ALFGLPLCEPIYPTPAGLVAAVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWP
AAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRRLLGELLDFAGSGAIYLEVRT
DNETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ
>Mature_358_residues
SIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVGM
ATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHAA
LFGLPLCEPIYPTPAGLVAAVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWPA
AAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRRLLGELLDFAGSGAIYLEVRTD
NETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ

Specific function: Unknown

COG id: COG1214

COG function: function code O; Inactive homolog of metal-dependent proteases, putative molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1788109, Length=131, Percent_Identity=33.587786259542, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y378_MYCLE (Q49857)

Other databases:

- EMBL:   U00020
- EMBL:   AL583918
- PIR:   S72977
- RefSeq:   NP_301370.1
- ProteinModelPortal:   Q49857
- SMR:   Q49857
- EnsemblBacteria:   EBMYCT00000027977
- GeneID:   909063
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0378
- NMPDR:   fig|272631.1.peg.242
- Leproma:   ML0378
- GeneTree:   EBGT00050000015588
- HOGENOM:   HBG129043
- OMA:   ELAAPLY
- ProtClustDB:   CLSK2460439
- BioCyc:   MLEP272631:ML0378-MONOMER
- GO:   GO:0006508
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR022496
- InterPro:   IPR000905
- InterPro:   IPR006464
- Gene3D:   G3DSA:3.40.630.30
- TIGRFAMs:   TIGR03725
- TIGRFAMs:   TIGR01575

Pfam domain/function: PF00583 Acetyltransf_1; PF00814 Peptidase_M22; SSF55729 Acyl_CoA_acyltransferase

EC number: NA

Molecular weight: Translated: 38018; Mature: 37887

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMC
CEEEEEECCHHHHHHEEEEEECCCCCEEHHHHEEECHHHHHHHCCCCEEEEEECCCEEEE
ELDAVVVGCGPGPFTGLRVGMATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARR
EEEEEEEECCCCCCCHHHHHHHHHHHHCCEECCCCCCEECCCEEEEEECCCEEEEECCCC
HEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHAALFGLPLCEPIYPTPAGLVA
CCEEEEEECCCEEEECCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEE
AVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWP
ECCCCCCCCHHEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCC
AAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRR
CHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHH
LLGELLDFAGSGAIYLEVRTDNETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ
HHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCHHCCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
SIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMC
EEEEEECCHHHHHHEEEEEECCCCCEEHHHHEEECHHHHHHHCCCCEEEEEECCCEEEE
ELDAVVVGCGPGPFTGLRVGMATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARR
EEEEEEEECCCCCCCHHHHHHHHHHHHCCEECCCCCCEECCCEEEEEECCCEEEEECCCC
HEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHAALFGLPLCEPIYPTPAGLVA
CCEEEEEECCCEEEECCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEE
AVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWP
ECCCCCCCCHHEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCC
AAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRR
CHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHH
LLGELLDFAGSGAIYLEVRTDNETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ
HHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCHHCCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002