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The map label for this gene is mer [H]

Identifier: 221229572

GI number: 221229572

Start: 438271

End: 439323

Strand: Direct

Name: mer [H]

Synonym: MLBr_00348

Alternate gene names: 221229572

Gene position: 438271-439323 (Clockwise)

Preceding gene: 221229567

Following gene: 221229573

Centisome position: 13.41

GC content: 62.39

Gene sequence:

>1053_bases
TTGGTGGAAAGGGCGAACGCCATGAAGCTTGGGCTGCAGTTGGGATATTGGGCTGCTCAACCGCCAGGAAACGCTGCCGA
ACTCGTGGCCGCGGCGGAGGGCGCCGGATTCGACGCAGTATTCACCGGGGAAGCGTGGGGATCCGATGCTTACACGCCGC
TGGCGTGGTGGGGCTCGTCCACGCAGCGGGTGCGGCTGGGCACGTCGGTGGTCCAACTGTCGGCGCGAACCCCGACGGCA
TGCGCGATGGCTGCGCTGACGCTGGACCATCTGTCCGGTGGACGCCATATTCTCGGGCTTGGTGTGTCCGGCCCACAGGT
GGTCGAGGGTTGGTATGGCCAGCCGTTTCCAAAGCCATTGTCCCGCACCCGTGAATACATTGACATTGTCCGCCAAGTGT
GGGCCAGGGAAGCGCCGGTGGTCAGCGACGGTCAGCACTACCCGTTGCCGCTGACCGGTGCTGGTGCGACGGGTTTAGGC
AAAGCGTTGAAACCCATCACCCATCCGCTGCGCGCAGACATTCCGATTATGCTGGGTGCCGAGGGGCCGAAGAACGTGGC
GCTGGCCGCCGAGATCTGCGACGGCTGGCTACCAATTTTCTTTTCTCCCCGGATGGCTGACATGTACAACGAATGGCTCG
ACGAGGGGTTCGCCCGGACGGGCGCGCGGCGCAGCCGTGAGGACTTCGAGATCTGTGCGTCCGCTCAGATCGTTGTTACC
GAAGACCGCGCGGCTGCGTTTGCCGGAATTAAGCCGTTCCTGGCACTTTACATGGGCGGTATGGGTGCTGAGGGCACCAA
CTTTCACGCCGACGTCTATCGTCGGATGGGCTATGCTGAGGTGGTCGACGAGGTGACTGCGCTGTTCCGGTCCAACCAGA
AGGACAAGGCGGCCGAGATCATCCCCAACGAGCTCGTCGACAGCACTATGATCGTCGGTGACGTGGACTATGTGTGTAAG
CAGATCGCGGCCTGGTCAGCCGCAGGGGTTACCATGATGATGGTGTCTGCTTCTAGCGTAGAGCAGGTTCGAGACCTGGC
TGGGCTGTTCTGA

Upstream 100 bases:

>100_bases
AATTGGTTCGGAGTGGTCGATCTAAGGATGTGCGGCTCGAACTGGTTGTCACGTCTTTGTTTAGAATCGGTTCTAAGAGC
GGTTTCAATAAGGTTGGGTT

Downstream 100 bases:

>100_bases
CCGCATCCTTGCTAGGCGATTAGAACGCCTTCTAGATTGACCGGATGGCGTTTGCTTCAGAATCCGTGAGTGTCGCCGGA
AGACCATATCCACGTTGGCC

Product: putative coenzyme F420-dependent oxidoreductase

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTA
CAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLG
KALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT
EDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCK
QIAAWSAAGVTMMMVSASSVEQVRDLAGLF

Sequences:

>Translated_350_residues
MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTA
CAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLG
KALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT
EDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCK
QIAAWSAAGVTMMMVSASSVEQVRDLAGLF
>Mature_350_residues
MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTA
CAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLG
KALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT
EDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCK
QIAAWSAAGVTMMMVSASSVEQVRDLAGLF

Specific function: Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 37558; Mature: 37558

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSS
CCCCCCHHHHHHEECEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCC
TQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPL
CCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCCCCHH
SRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCEEEEC
EGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT
CCCCCHHHHHHHHCCCEEEHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEE
EDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEI
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHH
IPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
CCHHHHCCEEEECCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCC
>Mature Secondary Structure
MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSS
CCCCCCHHHHHHEECEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCC
TQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPL
CCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCCCCHH
SRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCEEEEC
EGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT
CCCCCHHHHHHHHCCCEEEHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEE
EDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEI
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHH
IPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
CCHHHHCCEEEECCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]