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The map label for this gene is yjgI [C]

Identifier: 221229420

GI number: 221229420

Start: 149388

End: 150152

Strand: Reverse

Name: yjgI [C]

Synonym: MLBr_00108

Alternate gene names: 221229420

Gene position: 150152-149388 (Counterclockwise)

Preceding gene: 221229421

Following gene: 221229419

Centisome position: 4.59

GC content: 58.56

Gene sequence:

>765_bases
ATGGTGCTCGACGCCGTAGGACATCCGCAGACAGTGCTGCTGCTCGGGGGGACCTCCGAAATAGGACTGGCCATCTGCAA
GCGCTACCTGCGCAACGCCCCTGCGCGGATCGTGCTAGCCGCCATGCCCGACGATCCGAACCGTGAAGACGCGGTAGCAC
AGATGACGGCCGTGGGCGCGAGGTCAGTGGAGCTGATCGACTTCGAGGCGCTAGACACCGACAGTCATCCGAGAATGATC
GAGCAGGCATTTACCGGCGGTGACGTCGATGTGGCCATTGTCGCGTTCGGTTTACTCGGCGACGCAGAAGAGCTGTGGCA
GAACCAAAGCAAGGCTGTGCAGATCGCTGAAATCAACTACACCGCAGCAGTTTCTGTGGGAGTGCTGCTCGGCGAGAAGA
TGCGCGCGCAGGGGTTCGGCCAGATTATTGTCATGAGTTCAGCCGCCGGAGAGCGGGTGCGACGGTCCAACTTCGTCTAC
GGTTCCACCAAGGCTGGCCTGGACGGGTTCTACCTAGGATTGTCAGAGGCTTTACACGAGTACGGAGTTCACGTTCTGGT
TATCCGTCCAGGCCAGGTGCGCACCCGAATGAGCGCGCATGTCAAAGAAGCACCGCTGACTGTCAACAAGGAGTACGTAG
CCGACCTCGCGGTTACCGCAGCCGCTAAAGGTAAGGAATTGGTTTGGGCACCAGCAACATTCCGTTATGTGATGATGGTG
TTACGACACATCCCGCGAAGCATCTTCCGCAAACTACCAATCTGA

Upstream 100 bases:

>100_bases
TGTACCCGCGCATCGACGAGTGGATCGCTGTGCGCCGCAAGGTCGACCCCTTGCGGGTTTTCTCCTCCGACATGGCCCGA
CGTTTGGAGTTGCTCTAAAT

Downstream 100 bases:

>100_bases
CCATGCGCAATGCACTGGCCAGCTTCGGCCAGATTGTGTTGGCCGCCGTGGTGGCGAGCGGAGTGGCTGCAGTGTCGCTG
ATTGCCATTGCCCGGGTACA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNREDAVAQMTAVGARSVELIDFEALDTDSHPRMI
EQAFTGGDVDVAIVAFGLLGDAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIVMSSAAGERVRRSNFVY
GSTKAGLDGFYLGLSEALHEYGVHVLVIRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMV
LRHIPRSIFRKLPI

Sequences:

>Translated_254_residues
MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNREDAVAQMTAVGARSVELIDFEALDTDSHPRMI
EQAFTGGDVDVAIVAFGLLGDAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIVMSSAAGERVRRSNFVY
GSTKAGLDGFYLGLSEALHEYGVHVLVIRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMV
LRHIPRSIFRKLPI
>Mature_254_residues
MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNREDAVAQMTAVGARSVELIDFEALDTDSHPRMI
EQAFTGGDVDVAIVAFGLLGDAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIVMSSAAGERVRRSNFVY
GSTKAGLDGFYLGLSEALHEYGVHVLVIRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMV
LRHIPRSIFRKLPI

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the reduction of at C-2 of decaprenylphosphoryl 2-ket

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27529; Mature: 27529

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNREDAVAQMTAVGA
CEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCC
RSVELIDFEALDTDSHPRMIEQAFTGGDVDVAIVAFGLLGDAEELWQNQSKAVQIAEINY
CCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEHHHHHHCCCHHHHHCCCCCEEEEEEECC
TAAVSVGVLLGEKMRAQGFGQIIVMSSAAGERVRRSNFVYGSTKAGLDGFYLGLSEALHE
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCEEECCCCCCCCHHHHHHHHHHHH
YGVHVLVIRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMV
CCCEEEEECCCCHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
LRHIPRSIFRKLPI
HHHHHHHHHHHCCC
>Mature Secondary Structure
MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNREDAVAQMTAVGA
CEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCC
RSVELIDFEALDTDSHPRMIEQAFTGGDVDVAIVAFGLLGDAEELWQNQSKAVQIAEINY
CCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEHHHHHHCCCHHHHHCCCCCEEEEEEECC
TAAVSVGVLLGEKMRAQGFGQIIVMSSAAGERVRRSNFVYGSTKAGLDGFYLGLSEALHE
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCEEECCCCCCCCHHHHHHHHHHHH
YGVHVLVIRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMV
CCCEEEEECCCCHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
LRHIPRSIFRKLPI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]