| Definition | Mycobacterium leprae Br4923 chromosome, complete genome. |
|---|---|
| Accession | NC_011896 |
| Length | 3,268,071 |
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The map label for this gene is pks13 [H]
Identifier: 221229414
GI number: 221229414
Start: 126545
End: 131899
Strand: Direct
Name: pks13 [H]
Synonym: MLBr_00101
Alternate gene names: 221229414
Gene position: 126545-131899 (Clockwise)
Preceding gene: 221229413
Following gene: 221229415
Centisome position: 3.87
GC content: 60.8
Gene sequence:
>5355_bases ATGGCTGACGTAGACGCACCCCAATTGAACCAGGACCCTCCCCAATTGAACCAGGACCCTCAAGCGAACCTCCCCGCTGA GAAGACCAAGATGCGCTTCGGCGACGATGCAGAGCGAAGCGATGAGGAAGTGCGGCGTATAACACGCATAACAACTGTGC CCGAGATGCGGCAATGGTTGCGCAATTGGGTAGGTAAAGTCGTCGGGAAATCTCCCGACGACATCGACGAGTCGGCGCCT ATGGTGGAGCTCGGATTGGCGTCGCGGGATGCTGTGGCGATGGCCGCCGACATCGAAGATCTGACCGGAGTTACCCTGTC GGTTGCGGTGGCATTCCAGTATCCGACCATCGAATCTTTAGCGAACCGCATTATCGAGGGCGAATCGGAAACGATCGACG ACGACACCGACGCTTTCGACTGGTCGCGTACAGGCTCCGCAGAGCGCATCGATATCGCGGTGGTGGGCTTGTCGACGCGG CTGCCGGGAGATATGAACTCCCCCGAGGAAACCTGGCGGGCGCTGCTGGAAGGCCGCGACGCCATCACTGATCTGCCCGC CGGCCGTTGGTCGGAATTCCTTGGCGAACCACGGCTGGCGCAGCGAATCGCGCAGGCTCGCACTCGTGGCGGCTATTTGA AGGACATTAAGGGTTTTGACTCAGATTTCTTTGCTGTAGCCAAGACCGAAGCCGAAAACATCGACCCGCAGCAGCGGATG GCGCTGGAACTCACATGGGAAGCCCTCGAGCATGCCCGCATTCCCGCGTCGAGTCTGCGTGGCGAGGCTGTCGGCGTGTA TATCGGCAGCTCCACCAACGACTACAGCTTCTTAGCGGTTTCCGACCCAACGATAGCCCACCCCTATGCGATCACCGGTA CCAGCAGTTCTATTATCGCTAACCGGGTATCGTACTTCTACGATTTCCGCGGGCCGTCGGTCACTATCGATACCGCATGT TCGAGTTCGCTAGTGGCAATTCATCAGGGCGTGCAGGCACTGCGCAACGGCGAAGCCGATGTGGTTGTGGCCGGCGGTGT TAATGCCTTGATCACGCCAATGGTGACTCTTGGTTTCGACGAGATTGGTTCGGTGCTGGCTCCTGACGGACGGATCAAGT CCTTCTCGTCGGATGCCGATGGCTACACCCGCTCTGAGGGTGGCGGTGTGCTGGTACTCAAGCGGGTGAACGACGCCCGC CGTGACGGGGACCAGATCCTGGCGGTGATCGCCGGCAGCGCGGTAAACCATGACGGTCGGTCCAACGGTCTGATTGCACC CAACCAAGACGCTCAGGCCGACGTGCTGCGCCGGGCCTACAAGGACGCCGGTATCGACCCGCGTACCGTCGACTATATCG AAGCGCACGGCACCGGTACCGTCCTGGGTGACCCGATCGAGGCTGAGGCGCTAGGTCGCGTCGTGGGTAGGGGGCGTCCC GCTGATCGGCCGGCGTTGCTAGGTGCAGTGAAAACCAATGTGGGACACCTGGAATCGGCGGCTGGTGCCGCTAGCATGGT CAAAGTGGTGCTGGCTCTGCAGCATGACAAGTTGCCGCCGTCGATCAATTTCGCCGGACCCAGCCCGTACATCGACTTCG ATGCGATGCGCCTGAAGGTTATCGACACGGCGACCGACTGGCCGCGCTACGGCGGTTACGCGCTCGCCGGGGTGTCGAGC TTCGGTTTTGGCGGTGCCAACGCGCACCTGGTGGTGCGTGAGGTGTTGCCGAGGGATGTCATCGAACCTGAGCGGCAACC AGAGTCTCCTGTGCCAGCGGCGGCCACAACCGAGACAGCCATGCTGGAAGGCCGTGTACTGCGGTTTGACGAATGCGGCG AGATCATTACCGACGTCGCCGACTTTGGAGAATCTGAGCCCGAGCTGCCGGGTATGACCGACGAGGCGTTGCAGCTCAAG CAAGCTGCACTGGAAGCGCTTGCAGTAAAACAAGTTACGGCCCCCTTGATTCCGTTGGTAGTGTCATCATTTTTAACCTC ACGCAAGAAAGCCGCCGCTGCTGAGCTGGCGGATTGGATGGACAGCCCGCAAGGCCGTGCGTCGTCGCTGGAGTCGATTG GTCGATCGCTGTCACGGCGTAACCACGGTCGCTCCCGTGCAGTAGTGCTGGCCCATTACCATGACGAGGCTATCGAAGGT TTTCGGGCGATCGCCGAGGGCAAGCAGCGGCCGCACGTGTTCAGCGTCGACGGCCCGGTGACCAACGGCCCGGTGTGGGT GTTCGCCGGGTTCGGTGCGCAGCACCGCGAGATGGGCAAGAGCCTGTATTTACGAAACCAGGTCTTTGCCGAGTGGATTG AGAAGGTCGACGCCCTCGTGCAAGATGAGCGAGGCTATTCGGTGCTTGAGCTTATTCTAGATGATGCGCAGGATTACGGT ATCGAGACCACTCAGGTAACCATTTTCGCGATCCAGATCGCACTCGGTGAGCTGCTTAAGCATCACGGAGCCAAGCCTGC AGCAGTGGTCGGTCAGTCGCTAGGCGAGGCTGCATGCGCCTACTTTGTTGGTGGGTTGTCGTTGCGCGACGCGACTCGGG CGATCTGCTCGCGTTCGCATTTGATGGGTGAGGGCGAGGCGATGCTGTTTGGCGAGTACATCCGTCTGATGGCGTTGGTG GAGTACTCCGCCGACGAGATCAAGACGGTGTTCTCCGATTTCCCCGATTTAGAGGTGTGCGTCTACGCCGCACCCACCCA GATCGTCATCGGCGGTCCGCCTGAGCAGGTGGACGCGATCATCGCCCGCGCCAAAGCTGAGGGCAAGTTCGCCCGCAAAT TCGCAACCAAGGGCGCCAGCCACACCCAGCAGATGGATCCCCTGCTCGGCGAACTCGCTGCGGAACTGCAGGGCATCAAG CCGATGAGCCCGACTGCCGGCATCTACTCGACGGTGCACGAGGGCAGCTACATCAAGCCCGGCTCCGACCCGATTCACGA CGTGGATTATTGGAAGAAGGGGCTGCGTCACAGCGTCCATTTCACCCAAGGCATCCGCAATGCCGTCGACAACGGCCACA CCACGTTCTTGGAGTTGGCACCCAACGCGGTGGCGCTGATGCAGGTGGGTCTGACTACGGCAGCGGTTGGTTTGCATGAC GCACAGCTGATCCCGACGCTTTCCCGCAATCAAGACGAAGTGGAGTCGATGATCTCCACCATGGCGCAGCTTTATGTGTA TGGCCACGACTTGGACATCTGGACTCTGTTTAGTCGCGCCGTTGGACCCGAGGATTACGCGGACATTCCGCCGACCCGGT TCAAGCGCAAGGAACATTGGCTCGACGTGCATTTCGCCGGAGACGGTTCGGTGTCCATGCCGGGGAACCATGTTGCATTG CCGGATAGTCGACACGTCTGGGAATTCGCCCCCCGGGATAAAACGGATCTTGCGGCGTTGGTGAGAGCCGCTGTATCGCA AGTACTTCCGGGCGCACACTTGACGGCTGCCGAGCAGCGTGCGATGCCTGGCGCCGGCGCCAGACTGGTGACGATGTTGA CTCGACATCCAGGCGGTGCCTCGGTTCAGGTGCATGCCCGCATCGATGAATCCTTCACGCTGGTGTATGATGCATTGGTT GCGCGGGGAGGTCAAGAATCGGTTCTGCCGACGGCAGTAGGTGCGGGAACAGCGATCGCTTCGATCACGGTGCCGGCTGA TGCGGTGACGGTAGCCGCCGAGGAGTCGGACGCAGAAATCCTGTCAGATAGCCTGACCAACCGTTATCTACCGTCCGACA TGGGCAAGTGGTCACCCGATTCCGGCGAGACCATTGGTCACCGGTTGAGCACGATTGTGGCTGCGGCCATGGGTTACGAA CCTGAAGACCTGCCTTGGGAGGTGCCGCTGGTCGAGCTGGGTTTGGACTCGTTGATGGCGGTGCGGATCAAGAATCGTGT TGAGTACGATTTCGACCTGCCGCCGATCCAGTTGCAGGCCGTACGCGACGCTAATCTCTACAATGTCGAGAAGTTGATCG AGTATGCGATCAAGCACCGAGACGACGTCGAGCAGTTACACGAGTACCAGAAGACCCAGACGGCAGCGGCGATCGCCAAG GCGCAGATGGAACTGCTCAGTGGCGTGTCGCCGGTGACGCTGCCCGCTTCCGAGGCTCCGATTCCGCCGCCACCCACGGA CCCCACTGACCCGCCCAGTAACGGGGTGCAGCCCAATCTGGTAGCAGCTGCTGAGGCGCTTACCTCAGAAGCGGTTGCCA AGGTGCTCAACTCCGACGTACCGCCGCGTGATGCCGCCGAGCGGGTCACCTTCGCTGCCTGGGCGATCGTCACTGGAAAG TCCCCAGGCGGCATTTTCGATACTTTGCCCAAACTGGATGGTGACACTGCTGCCAAGATGGCGCAGCGGCTTTCCGAGCG CGCTGAAGGGACGATCACTGCCGAGGACGTGCTGACGTCGGAGAACATCGAGGCGCTGGCCGGCAAGGTGCGCAACTATT TGGAGGCTGGACAGATCGATGGGTTCGTCCGCGCTATCCGGCCTCGGGCCGAGGACAGTGCAGAGGGCCCCGCAGGTGAA TCCAGAGTGCCGGTGTTTGTTTTCCACCCCGCAGGAGGCTCGACCGTGGTATACGAGCCGTTGCTCAAACGGCTGCCTGC TGATACCCCGATGTACGGCTTCGAGCGGGTTGAAGGCTCGATCGAAGAGCGTGTGGCGGTCTACGTGCCGAAGCTAATCG AGATGCAAGGCGACGGCCCCTACATTCTGGCCGGTTGGTCGTTGGGCGGGGTGCTAGCCTACGCGTGTGCGATCGGGCTG AGGAGCGCGGGTAAAGAGGTCGCGTGGGTGGGGTTGATCGACGCGGTACGTGCGGGCGAGGAGATCCCGCAGACCAAGGA GGAGATCCGAAAGCGCTGGGACCGTTACGCGCGGTTCGCTGAGAGGACCTTCAACGTTACCGTCCCGGAGATCCCTTACG AGCAGCTTGAGGAACTTGACGACGAGGGTCAGGTTCGGTTTGTGCTGGACGTCGTCAGCCAAAGTGGTGTACAGATTCCG GCTGGAATCATCGACCACCAGCGCACGTCGTATCTGGATAACCGGGCGATCGACACTGCCCAGATTCAGCCATACGACGG GCATGTCACCTTGTATATGGCTGATCGCTACCACGACGACGCGATCATGTTCGAGCCGCGCTATGCCGTCCGTAAACCGG ACGGCGGCTGGGGAGAGTACGTTTCCGATCTCGAAGTGGTGCCGATCGGTGGCGAGCACATCCAGGCCATCGACGAACCG ATCATCGCTAAGGTGGGCGAACATATGAGCCAGGCGTTGAACAAGATTGAGGCTGAGCAGAAGGCGCCCAAATGA
Upstream 100 bases:
>100_bases TCGGCCGGCGCGCCTGCCGCGCCGCCTACATTGACGGTAGTCTGCGCAGCGGCGCCAGCTCTCCGACGGTTTTCGCTGCT GAATTCTGAGCAAGGCACAC
Downstream 100 bases:
>100_bases TTATGAAGAGTACAGCCGAGAAGCTGGCTGAGCTTCGCGTTCGGCTGGAGTTGGCCAACGAGCCCGGAGGTGAAAAGGCC GCCGCCAAGCGCGACAAGAA
Product: polyketide synthase
Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 1784; Mature: 1783
Protein sequence:
>1784_residues MADVDAPQLNQDPPQLNQDPQANLPAEKTKMRFGDDAERSDEEVRRITRITTVPEMRQWLRNWVGKVVGKSPDDIDESAP MVELGLASRDAVAMAADIEDLTGVTLSVAVAFQYPTIESLANRIIEGESETIDDDTDAFDWSRTGSAERIDIAVVGLSTR LPGDMNSPEETWRALLEGRDAITDLPAGRWSEFLGEPRLAQRIAQARTRGGYLKDIKGFDSDFFAVAKTEAENIDPQQRM ALELTWEALEHARIPASSLRGEAVGVYIGSSTNDYSFLAVSDPTIAHPYAITGTSSSIIANRVSYFYDFRGPSVTIDTAC SSSLVAIHQGVQALRNGEADVVVAGGVNALITPMVTLGFDEIGSVLAPDGRIKSFSSDADGYTRSEGGGVLVLKRVNDAR RDGDQILAVIAGSAVNHDGRSNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYIEAHGTGTVLGDPIEAEALGRVVGRGRP ADRPALLGAVKTNVGHLESAAGAASMVKVVLALQHDKLPPSINFAGPSPYIDFDAMRLKVIDTATDWPRYGGYALAGVSS FGFGGANAHLVVREVLPRDVIEPERQPESPVPAAATTETAMLEGRVLRFDECGEIITDVADFGESEPELPGMTDEALQLK QAALEALAVKQVTAPLIPLVVSSFLTSRKKAAAAELADWMDSPQGRASSLESIGRSLSRRNHGRSRAVVLAHYHDEAIEG FRAIAEGKQRPHVFSVDGPVTNGPVWVFAGFGAQHREMGKSLYLRNQVFAEWIEKVDALVQDERGYSVLELILDDAQDYG IETTQVTIFAIQIALGELLKHHGAKPAAVVGQSLGEAACAYFVGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALV EYSADEIKTVFSDFPDLEVCVYAAPTQIVIGGPPEQVDAIIARAKAEGKFARKFATKGASHTQQMDPLLGELAAELQGIK PMSPTAGIYSTVHEGSYIKPGSDPIHDVDYWKKGLRHSVHFTQGIRNAVDNGHTTFLELAPNAVALMQVGLTTAAVGLHD AQLIPTLSRNQDEVESMISTMAQLYVYGHDLDIWTLFSRAVGPEDYADIPPTRFKRKEHWLDVHFAGDGSVSMPGNHVAL PDSRHVWEFAPRDKTDLAALVRAAVSQVLPGAHLTAAEQRAMPGAGARLVTMLTRHPGGASVQVHARIDESFTLVYDALV ARGGQESVLPTAVGAGTAIASITVPADAVTVAAEESDAEILSDSLTNRYLPSDMGKWSPDSGETIGHRLSTIVAAAMGYE PEDLPWEVPLVELGLDSLMAVRIKNRVEYDFDLPPIQLQAVRDANLYNVEKLIEYAIKHRDDVEQLHEYQKTQTAAAIAK AQMELLSGVSPVTLPASEAPIPPPPTDPTDPPSNGVQPNLVAAAEALTSEAVAKVLNSDVPPRDAAERVTFAAWAIVTGK SPGGIFDTLPKLDGDTAAKMAQRLSERAEGTITAEDVLTSENIEALAGKVRNYLEAGQIDGFVRAIRPRAEDSAEGPAGE SRVPVFVFHPAGGSTVVYEPLLKRLPADTPMYGFERVEGSIEERVAVYVPKLIEMQGDGPYILAGWSLGGVLAYACAIGL RSAGKEVAWVGLIDAVRAGEEIPQTKEEIRKRWDRYARFAERTFNVTVPEIPYEQLEELDDEGQVRFVLDVVSQSGVQIP AGIIDHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRKPDGGWGEYVSDLEVVPIGGEHIQAIDEP IIAKVGEHMSQALNKIEAEQKAPK
Sequences:
>Translated_1784_residues MADVDAPQLNQDPPQLNQDPQANLPAEKTKMRFGDDAERSDEEVRRITRITTVPEMRQWLRNWVGKVVGKSPDDIDESAP MVELGLASRDAVAMAADIEDLTGVTLSVAVAFQYPTIESLANRIIEGESETIDDDTDAFDWSRTGSAERIDIAVVGLSTR LPGDMNSPEETWRALLEGRDAITDLPAGRWSEFLGEPRLAQRIAQARTRGGYLKDIKGFDSDFFAVAKTEAENIDPQQRM ALELTWEALEHARIPASSLRGEAVGVYIGSSTNDYSFLAVSDPTIAHPYAITGTSSSIIANRVSYFYDFRGPSVTIDTAC SSSLVAIHQGVQALRNGEADVVVAGGVNALITPMVTLGFDEIGSVLAPDGRIKSFSSDADGYTRSEGGGVLVLKRVNDAR RDGDQILAVIAGSAVNHDGRSNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYIEAHGTGTVLGDPIEAEALGRVVGRGRP ADRPALLGAVKTNVGHLESAAGAASMVKVVLALQHDKLPPSINFAGPSPYIDFDAMRLKVIDTATDWPRYGGYALAGVSS FGFGGANAHLVVREVLPRDVIEPERQPESPVPAAATTETAMLEGRVLRFDECGEIITDVADFGESEPELPGMTDEALQLK QAALEALAVKQVTAPLIPLVVSSFLTSRKKAAAAELADWMDSPQGRASSLESIGRSLSRRNHGRSRAVVLAHYHDEAIEG FRAIAEGKQRPHVFSVDGPVTNGPVWVFAGFGAQHREMGKSLYLRNQVFAEWIEKVDALVQDERGYSVLELILDDAQDYG IETTQVTIFAIQIALGELLKHHGAKPAAVVGQSLGEAACAYFVGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALV EYSADEIKTVFSDFPDLEVCVYAAPTQIVIGGPPEQVDAIIARAKAEGKFARKFATKGASHTQQMDPLLGELAAELQGIK PMSPTAGIYSTVHEGSYIKPGSDPIHDVDYWKKGLRHSVHFTQGIRNAVDNGHTTFLELAPNAVALMQVGLTTAAVGLHD AQLIPTLSRNQDEVESMISTMAQLYVYGHDLDIWTLFSRAVGPEDYADIPPTRFKRKEHWLDVHFAGDGSVSMPGNHVAL PDSRHVWEFAPRDKTDLAALVRAAVSQVLPGAHLTAAEQRAMPGAGARLVTMLTRHPGGASVQVHARIDESFTLVYDALV ARGGQESVLPTAVGAGTAIASITVPADAVTVAAEESDAEILSDSLTNRYLPSDMGKWSPDSGETIGHRLSTIVAAAMGYE PEDLPWEVPLVELGLDSLMAVRIKNRVEYDFDLPPIQLQAVRDANLYNVEKLIEYAIKHRDDVEQLHEYQKTQTAAAIAK AQMELLSGVSPVTLPASEAPIPPPPTDPTDPPSNGVQPNLVAAAEALTSEAVAKVLNSDVPPRDAAERVTFAAWAIVTGK SPGGIFDTLPKLDGDTAAKMAQRLSERAEGTITAEDVLTSENIEALAGKVRNYLEAGQIDGFVRAIRPRAEDSAEGPAGE SRVPVFVFHPAGGSTVVYEPLLKRLPADTPMYGFERVEGSIEERVAVYVPKLIEMQGDGPYILAGWSLGGVLAYACAIGL RSAGKEVAWVGLIDAVRAGEEIPQTKEEIRKRWDRYARFAERTFNVTVPEIPYEQLEELDDEGQVRFVLDVVSQSGVQIP AGIIDHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRKPDGGWGEYVSDLEVVPIGGEHIQAIDEP IIAKVGEHMSQALNKIEAEQKAPK >Mature_1783_residues ADVDAPQLNQDPPQLNQDPQANLPAEKTKMRFGDDAERSDEEVRRITRITTVPEMRQWLRNWVGKVVGKSPDDIDESAPM VELGLASRDAVAMAADIEDLTGVTLSVAVAFQYPTIESLANRIIEGESETIDDDTDAFDWSRTGSAERIDIAVVGLSTRL PGDMNSPEETWRALLEGRDAITDLPAGRWSEFLGEPRLAQRIAQARTRGGYLKDIKGFDSDFFAVAKTEAENIDPQQRMA LELTWEALEHARIPASSLRGEAVGVYIGSSTNDYSFLAVSDPTIAHPYAITGTSSSIIANRVSYFYDFRGPSVTIDTACS SSLVAIHQGVQALRNGEADVVVAGGVNALITPMVTLGFDEIGSVLAPDGRIKSFSSDADGYTRSEGGGVLVLKRVNDARR DGDQILAVIAGSAVNHDGRSNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYIEAHGTGTVLGDPIEAEALGRVVGRGRPA DRPALLGAVKTNVGHLESAAGAASMVKVVLALQHDKLPPSINFAGPSPYIDFDAMRLKVIDTATDWPRYGGYALAGVSSF GFGGANAHLVVREVLPRDVIEPERQPESPVPAAATTETAMLEGRVLRFDECGEIITDVADFGESEPELPGMTDEALQLKQ AALEALAVKQVTAPLIPLVVSSFLTSRKKAAAAELADWMDSPQGRASSLESIGRSLSRRNHGRSRAVVLAHYHDEAIEGF RAIAEGKQRPHVFSVDGPVTNGPVWVFAGFGAQHREMGKSLYLRNQVFAEWIEKVDALVQDERGYSVLELILDDAQDYGI ETTQVTIFAIQIALGELLKHHGAKPAAVVGQSLGEAACAYFVGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALVE YSADEIKTVFSDFPDLEVCVYAAPTQIVIGGPPEQVDAIIARAKAEGKFARKFATKGASHTQQMDPLLGELAAELQGIKP MSPTAGIYSTVHEGSYIKPGSDPIHDVDYWKKGLRHSVHFTQGIRNAVDNGHTTFLELAPNAVALMQVGLTTAAVGLHDA QLIPTLSRNQDEVESMISTMAQLYVYGHDLDIWTLFSRAVGPEDYADIPPTRFKRKEHWLDVHFAGDGSVSMPGNHVALP DSRHVWEFAPRDKTDLAALVRAAVSQVLPGAHLTAAEQRAMPGAGARLVTMLTRHPGGASVQVHARIDESFTLVYDALVA RGGQESVLPTAVGAGTAIASITVPADAVTVAAEESDAEILSDSLTNRYLPSDMGKWSPDSGETIGHRLSTIVAAAMGYEP EDLPWEVPLVELGLDSLMAVRIKNRVEYDFDLPPIQLQAVRDANLYNVEKLIEYAIKHRDDVEQLHEYQKTQTAAAIAKA QMELLSGVSPVTLPASEAPIPPPPTDPTDPPSNGVQPNLVAAAEALTSEAVAKVLNSDVPPRDAAERVTFAAWAIVTGKS PGGIFDTLPKLDGDTAAKMAQRLSERAEGTITAEDVLTSENIEALAGKVRNYLEAGQIDGFVRAIRPRAEDSAEGPAGES RVPVFVFHPAGGSTVVYEPLLKRLPADTPMYGFERVEGSIEERVAVYVPKLIEMQGDGPYILAGWSLGGVLAYACAIGLR SAGKEVAWVGLIDAVRAGEEIPQTKEEIRKRWDRYARFAERTFNVTVPEIPYEQLEELDDEGQVRFVLDVVSQSGVQIPA GIIDHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRKPDGGWGEYVSDLEVVPIGGEHIQAIDEPI IAKVGEHMSQALNKIEAEQKAPK
Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]
COG id: COG3321
COG function: function code Q; Polyketide synthase modules and related proteins
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 acyl carrier domains [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=455, Percent_Identity=37.5824175824176, Blast_Score=293, Evalue=9e-79, Organism=Homo sapiens, GI8923559, Length=288, Percent_Identity=30.2083333333333, Blast_Score=129, Evalue=3e-29, Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=2e-13, Organism=Escherichia coli, GI1787337, Length=440, Percent_Identity=27.0454545454545, Blast_Score=132, Evalue=1e-31, Organism=Escherichia coli, GI1788663, Length=293, Percent_Identity=29.3515358361775, Blast_Score=110, Evalue=6e-25, Organism=Escherichia coli, GI1786801, Length=328, Percent_Identity=24.6951219512195, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI212642053, Length=470, Percent_Identity=36.1702127659575, Blast_Score=283, Evalue=7e-76, Organism=Caenorhabditis elegans, GI17550940, Length=510, Percent_Identity=33.921568627451, Blast_Score=233, Evalue=6e-61, Organism=Caenorhabditis elegans, GI71983541, Length=344, Percent_Identity=26.453488372093, Blast_Score=117, Evalue=8e-26, Organism=Caenorhabditis elegans, GI71983535, Length=272, Percent_Identity=29.0441176470588, Blast_Score=108, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6320904, Length=450, Percent_Identity=26.2222222222222, Blast_Score=129, Evalue=5e-30, Organism=Drosophila melanogaster, GI221330659, Length=460, Percent_Identity=36.304347826087, Blast_Score=280, Evalue=5e-75, Organism=Drosophila melanogaster, GI19920632, Length=460, Percent_Identity=36.304347826087, Blast_Score=280, Evalue=7e-75, Organism=Drosophila melanogaster, GI24581345, Length=434, Percent_Identity=37.0967741935484, Blast_Score=271, Evalue=4e-72, Organism=Drosophila melanogaster, GI24644341, Length=440, Percent_Identity=30.2272727272727, Blast_Score=157, Evalue=1e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR000794 - InterPro: IPR002198 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020842 - InterPro: IPR020801 - InterPro: IPR020841 - InterPro: IPR020806 - InterPro: IPR006162 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]
EC number: 2.3.1.41 [C]
Molecular weight: Translated: 192783; Mature: 192652
Theoretical pI: Translated: 4.60; Mature: 4.60
Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADVDAPQLNQDPPQLNQDPQANLPAEKTKMRFGDDAERSDEEVRRITRITTVPEMRQWL CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHH RNWVGKVVGKSPDDIDESAPMVELGLASRDAVAMAADIEDLTGVTLSVAVAFQYPTIESL HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHCHHHHCCCEEEEEEEECCCCHHHH ANRIIEGESETIDDDTDAFDWSRTGSAERIDIAVVGLSTRLPGDMNSPEETWRALLEGRD HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCH AITDLPAGRWSEFLGEPRLAQRIAQARTRGGYLKDIKGFDSDFFAVAKTEAENIDPQQRM HHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHH ALELTWEALEHARIPASSLRGEAVGVYIGSSTNDYSFLAVSDPTIAHPYAITGTSSSIIA HHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCHHHHH NRVSYFYDFRGPSVTIDTACSSSLVAIHQGVQALRNGEADVVVAGGVNALITPMVTLGFD HHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCHH EIGSVLAPDGRIKSFSSDADGYTRSEGGGVLVLKRVNDARRDGDQILAVIAGSAVNHDGR HHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCHHHEEEEHCCCCCCCCCC SNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYIEAHGTGTVLGDPIEAEALGRVVGRGRP CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHCCCC ADRPALLGAVKTNVGHLESAAGAASMVKVVLALQHDKLPPSINFAGPSPYIDFDAMRLKV CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE IDTATDWPRYGGYALAGVSSFGFGGANAHLVVREVLPRDVIEPERQPESPVPAAATTETA EECCCCCCCCCCEEEECHHHCCCCCCCHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCHHH MLEGRVLRFDECGEIITDVADFGESEPELPGMTDEALQLKQAALEALAVKQVTAPLIPLV HHCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH VSSFLTSRKKAAAAELADWMDSPQGRASSLESIGRSLSRRNHGRSRAVVLAHYHDEAIEG HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH FRAIAEGKQRPHVFSVDGPVTNGPVWVFAGFGAQHREMGKSLYLRNQVFAEWIEKVDALV HHHHHCCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH QDERGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLKHHGAKPAAVVGQSLGEAACA HCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH YFVGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIKTVFSDFPDLEVC HHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEE VYAAPTQIVIGGPPEQVDAIIARAKAEGKFARKFATKGASHTQQMDPLLGELAAELQGIK EEECCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC PMSPTAGIYSTVHEGSYIKPGSDPIHDVDYWKKGLRHSVHFTQGIRNAVDNGHTTFLELA CCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC PNAVALMQVGLTTAAVGLHDAQLIPTLSRNQDEVESMISTMAQLYVYGHDLDIWTLFSRA CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH VGPEDYADIPPTRFKRKEHWLDVHFAGDGSVSMPGNHVALPDSRHVWEFAPRDKTDLAAL CCCCCCCCCCCHHHCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCEEECCCCHHHHHHH VRAAVSQVLPGAHLTAAEQRAMPGAGARLVTMLTRHPGGASVQVHARIDESFTLVYDALV HHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH ARGGQESVLPTAVGAGTAIASITVPADAVTVAAEESDAEILSDSLTNRYLPSDMGKWSPD HCCCCCCCCCHHHCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC SGETIGHRLSTIVAAAMGYEPEDLPWEVPLVELGLDSLMAVRIKNRVEYDFDLPPIQLQA CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEE VRDANLYNVEKLIEYAIKHRDDVEQLHEYQKTQTAAAIAKAQMELLSGVSPVTLPASEAP ECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCC IPPPPTDPTDPPSNGVQPNLVAAAEALTSEAVAKVLNSDVPPRDAAERVTFAAWAIVTGK CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEEEEEECC SPGGIFDTLPKLDGDTAAKMAQRLSERAEGTITAEDVLTSENIEALAGKVRNYLEAGQID CCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHCHHHHHHHHHHHHHHHCCHH GFVRAIRPRAEDSAEGPAGESRVPVFVFHPAGGSTVVYEPLLKRLPADTPMYGFERVEGS HHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHHCCH IEERVAVYVPKLIEMQGDGPYILAGWSLGGVLAYACAIGLRSAGKEVAWVGLIDAVRAGE HHHHHHHHCCHHHEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCC EIPQTKEEIRKRWDRYARFAERTFNVTVPEIPYEQLEELDDEGQVRFVLDVVSQSGVQIP CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCCCCCCCEEEEEEHHHCCCCCCC AGIIDHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRKPDGGWGEY HHHHCCHHHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCEEEECCCHHEECCCCCHHHH VSDLEVVPIGGEHIQAIDEPIIAKVGEHMSQALNKIEAEQKAPK HCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure ADVDAPQLNQDPPQLNQDPQANLPAEKTKMRFGDDAERSDEEVRRITRITTVPEMRQWL CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHH RNWVGKVVGKSPDDIDESAPMVELGLASRDAVAMAADIEDLTGVTLSVAVAFQYPTIESL HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHCHHHHCCCEEEEEEEECCCCHHHH ANRIIEGESETIDDDTDAFDWSRTGSAERIDIAVVGLSTRLPGDMNSPEETWRALLEGRD HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCH AITDLPAGRWSEFLGEPRLAQRIAQARTRGGYLKDIKGFDSDFFAVAKTEAENIDPQQRM HHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHH ALELTWEALEHARIPASSLRGEAVGVYIGSSTNDYSFLAVSDPTIAHPYAITGTSSSIIA HHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCHHHHH NRVSYFYDFRGPSVTIDTACSSSLVAIHQGVQALRNGEADVVVAGGVNALITPMVTLGFD HHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCHH EIGSVLAPDGRIKSFSSDADGYTRSEGGGVLVLKRVNDARRDGDQILAVIAGSAVNHDGR HHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCHHHEEEEHCCCCCCCCCC SNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYIEAHGTGTVLGDPIEAEALGRVVGRGRP CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHCCCC ADRPALLGAVKTNVGHLESAAGAASMVKVVLALQHDKLPPSINFAGPSPYIDFDAMRLKV CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE IDTATDWPRYGGYALAGVSSFGFGGANAHLVVREVLPRDVIEPERQPESPVPAAATTETA EECCCCCCCCCCEEEECHHHCCCCCCCHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCHHH MLEGRVLRFDECGEIITDVADFGESEPELPGMTDEALQLKQAALEALAVKQVTAPLIPLV HHCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH VSSFLTSRKKAAAAELADWMDSPQGRASSLESIGRSLSRRNHGRSRAVVLAHYHDEAIEG HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH FRAIAEGKQRPHVFSVDGPVTNGPVWVFAGFGAQHREMGKSLYLRNQVFAEWIEKVDALV HHHHHCCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH QDERGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLKHHGAKPAAVVGQSLGEAACA HCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH YFVGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIKTVFSDFPDLEVC HHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEE VYAAPTQIVIGGPPEQVDAIIARAKAEGKFARKFATKGASHTQQMDPLLGELAAELQGIK EEECCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC PMSPTAGIYSTVHEGSYIKPGSDPIHDVDYWKKGLRHSVHFTQGIRNAVDNGHTTFLELA CCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC PNAVALMQVGLTTAAVGLHDAQLIPTLSRNQDEVESMISTMAQLYVYGHDLDIWTLFSRA CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH VGPEDYADIPPTRFKRKEHWLDVHFAGDGSVSMPGNHVALPDSRHVWEFAPRDKTDLAAL CCCCCCCCCCCHHHCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCEEECCCCHHHHHHH VRAAVSQVLPGAHLTAAEQRAMPGAGARLVTMLTRHPGGASVQVHARIDESFTLVYDALV HHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH ARGGQESVLPTAVGAGTAIASITVPADAVTVAAEESDAEILSDSLTNRYLPSDMGKWSPD HCCCCCCCCCHHHCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC SGETIGHRLSTIVAAAMGYEPEDLPWEVPLVELGLDSLMAVRIKNRVEYDFDLPPIQLQA CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEE VRDANLYNVEKLIEYAIKHRDDVEQLHEYQKTQTAAAIAKAQMELLSGVSPVTLPASEAP ECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCC IPPPPTDPTDPPSNGVQPNLVAAAEALTSEAVAKVLNSDVPPRDAAERVTFAAWAIVTGK CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEEEEEECC SPGGIFDTLPKLDGDTAAKMAQRLSERAEGTITAEDVLTSENIEALAGKVRNYLEAGQID CCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHCHHHHHHHHHHHHHHHCCHH GFVRAIRPRAEDSAEGPAGESRVPVFVFHPAGGSTVVYEPLLKRLPADTPMYGFERVEGS HHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHHCCH IEERVAVYVPKLIEMQGDGPYILAGWSLGGVLAYACAIGLRSAGKEVAWVGLIDAVRAGE HHHHHHHHCCHHHEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCC EIPQTKEEIRKRWDRYARFAERTFNVTVPEIPYEQLEELDDEGQVRFVLDVVSQSGVQIP CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCCCCCCCEEEEEEHHHCCCCCCC AGIIDHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRKPDGGWGEY HHHHCCHHHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCEEEECCCHHEECCCCCHHHH VSDLEVVPIGGEHIQAIDEPIIAKVGEHMSQALNKIEAEQKAPK HCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: None [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]
Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]
Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]
General reaction: Acyl group transfer [C]
Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]