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The map label for this gene is menG [C]

Identifier: 221229389

GI number: 221229389

Start: 88273

End: 88746

Strand: Reverse

Name: menG [C]

Synonym: MLBr_00066

Alternate gene names: 221229389

Gene position: 88746-88273 (Counterclockwise)

Preceding gene: 221229390

Following gene: 221229387

Centisome position: 2.72

GC content: 60.97

Gene sequence:

>474_bases
GTGATCGTGTCATTTCGGCCAACCGCCGACCTCGTCGACAGCATCGGGGTCGACGTACGCAGCTGCGATCTTCAGTTTCG
CCAGTTCGGCGGCTGCTCGGAGTTCGCCGGCCCGATCAGTACCGTCCGTTGTTTCCAGGACAATGCGCTACTCAAATCGG
TACTCTCCCAGACGAGTGCGGGTGGAGTGCTGGTGGTCGACGGCGCCGGTTCCCTGCACACCGCCTTGGTCGGTGACGTG
ATCGCCGAATTGGCCCACTCCAACGGCTGGGCCGGCCTAATCGTCAATGGTGCAGTGCGAGACGCAGCCGCACTGCGCGG
TATCGACATTGGCATCAAGGCGCTAGGCACCAATCCACGCAAAAGTACTAAGATCGGCACCGGGGAACGCCACGTCGAGG
TCAACCTGGGTGGTGTGACATTCGTTCCGGGAGAAGTCGTCTACAGTGACGACGACGGCATTGTCGTCGTCTAA

Upstream 100 bases:

>100_bases
TTCACCGGTAGCACTGGTGATCGCGTTGGCAATCGGTCTACTGGCCCTGCTGCTTATCCACCAACTGCGACGTCGCTGAC
CGCCTACCGACAGACCAGCA

Downstream 100 bases:

>100_bases
TTGTAGTGACCCCCGGCTCAGCTACTACGGCTGAATGCTGGCAGCCCGCTTAACCCGCTCCCACCGTACTCGCTATCGCC
CTAAACCGTAACGGGAGTAG

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSAGGVLVVDGAGSLHTALVGDV
IAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPRKSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV

Sequences:

>Translated_157_residues
MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSAGGVLVVDGAGSLHTALVGDV
IAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPRKSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV
>Mature_157_residues
MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSAGGVLVVDGAGSLHTALVGDV
IAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPRKSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV

Specific function: Regulator Of Rnase E/Rne, Which Inhibits The Endonuclease Activity And Thereby Leads To Increase The Half-Life And Abundance Of Rnas. General Modulator Of RNA Abundance. Does Not Have Any Methyltransferase Activity. [C]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family

Homologues:

Organism=Escherichia coli, GI1790364, Length=149, Percent_Identity=45.6375838926174, Blast_Score=123, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RRAAH_MYCLB (B8ZTT3)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002502805.1
- ProteinModelPortal:   B8ZTT3
- SMR:   B8ZTT3
- EnsemblBacteria:   EBMYCT00000087198
- GeneID:   7325810
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000015945
- HOGENOM:   HBG668175
- OMA:   QNEWEGI
- ProtClustDB:   PRK09372
- InterPro:   IPR005493
- InterPro:   IPR010203
- Gene3D:   G3DSA:3.50.30.40
- TIGRFAMs:   TIGR01935

Pfam domain/function: PF03737 Methyltransf_6; SSF89562 RNaseE_inh/diMeMenaQ_MeTrfase

EC number: NA

Molecular weight: Translated: 16194; Mature: 16194

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSA
CEEECCCCHHHHHHHCCCEEECCCHHHHCCCCCHHCCCHHHEEHHCCCHHHHHHHHHCCC
GGVLVVDGAGSLHTALVGDVIAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPR
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCEEEEEEECCCCC
KSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV
CCCCCCCCCEEEEEEECCEEECCCEEEEECCCCEEEC
>Mature Secondary Structure
MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSA
CEEECCCCHHHHHHHCCCEEECCCHHHHCCCCCHHCCCHHHEEHHCCCHHHHHHHHHCCC
GGVLVVDGAGSLHTALVGDVIAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPR
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCEEEEEEECCCCC
KSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV
CCCCCCCCCEEEEEEECCEEECCCEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA