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The map label for this gene is ftsK [H]

Identifier: 220919425

GI number: 220919425

Start: 4835303

End: 4838098

Strand: Direct

Name: ftsK [H]

Synonym: A2cp1_4346

Alternate gene names: 220919425

Gene position: 4835303-4838098 (Clockwise)

Preceding gene: 220919415

Following gene: 220919426

Centisome position: 96.14

GC content: 73.71

Gene sequence:

>2796_bases
ATGGGCAAGCCCAAAGCCAATCGCCGTGTCTCCCCGAAGGAAAAGGGAAAGCGCGGCGACCCGCCCGCCGAGCGCGCGAA
GGGCGGCGCCGCCCCGCGCACCGGCATGGCGCGCGACGTCGGCGCGGTGGTCCTGTTCGCCGCCGCGCTCGGCAGCGGCC
TCTCGCTCGCGACCTACTCCTCGCTCGACGCGGCGCTGATCGCGCACGGCATCGCGCCCGCCAACCTGGTCGGCCCGGTC
GGCCACCGGACCGCGTCCGCGCTGTACGGCGTGCTGGGCCTCTCGGCCCTGGTGCTCCCGTTCGGCCTGGGCGCCGCGGC
CTGGCGCCTCTTCCGCGGCGCGCCCCCGCGCATCACGCTCGTGTCGGCCGGCGCGTACACCGTGCTCACGCTCTCGGTGG
CGACGCTCGGGCACCTGGCGCTCGCCGGCAGCGTCTCGCTCCCGTTCCCGCCCGGCGGCGCGGTGGGCGCCGCGCTCGCG
CGGCCGAGCGTCCACGCGTTCTCGCTGTGGGGCAGCGTCATCCTGGTGGGCGCCACCGCCACGGTGGCGGCCATCGTGGC
CTGCGACCTGAAGGTGCAGACGGTGGGCGCCGCGCTCTGGCGCGCGCTCGCCGCCACCGCCGGCTTCCTCTCGCGCCGCC
TCGCCACCGCGGTCGACGAGCACCGCGTCGCCGTCGCCGAGCTGCGCGCCGAGGAGGCCGCCGAGCGCGAGCGCCGGCTC
GCGGCCGAGCAGCTCGCCGAGACGGCCGAGATCGAGGCGAACGGCGAGGAGGCGCACGAGGAGGCCCGCGCCGTGGCCGG
CGCGCTCGCGCTCGAGCAGCTCCGCCGCGACACGTTCGAGGATCCGGCCTGGGTGGAGGGGCTCGCCCCCGCGCCCGAGC
CGCGCGAGGAGGCCGAGGGCGCCGGAGAGGGCGAGCCGGCCGCCGAGGAGCCGCCGCGCCGCCGCCGCAAGGCGCGCGAG
CCGGAGAAGGCGGTCGACGTGCGGGCCGAGCTCGAGGACCCCGCCGCGCTGCCGGTCCCGGCGCGCGCCGAGAAGCCGGA
GATCGTGGTCTCGCAGGCGATGCTGGAGCGCGCCCGCAAGAAGGAGAAGAAGAAGGAGGCGCCCGCCTTCGCGTTCCAGA
AGGCCGGCGACGTGTTCCAGCTCCCGGCCACCGACCTGCTCGACGTCCACGACGAGAAGGCGAAGGACCTCGACACGGCC
GGCCTGACGCGCACGGCCGAGGTGATCGTCGCGACGCTCGCCCAGCACGGCGTGGACGGGACCATCAAGCACATCCGGCC
CGGGCCGGTGGTGACGCTCTACGAGTTCTCCCCGGTCGCGGGCGTGAAGCTCGCGCGGATCGAGAACCTCGACAAGGAGC
TCACCATGGCGCTCAGCGCCACCCGGATCCGCATCATCGCGCCGATCCCGGGCAAGGGCGTGGTGGGCATCGAGGTCCCG
AACCGCGACCGCGCCACCGTGTGGCTGCGCGACATCCTCGAGTCGGAGTCGTTCGCCTCGGCGGGCGGCTTCCTGCCGCT
CGGCCTCGGCAAGAACATCGAGGGCATCCCGTACTGCGTGGACCTGCAGCGGATGCCGCACCTGCTCATCGCCGGCACCA
CCGGCTCGGGCAAGTCGGTCGGCCTCAACACCATGATCCTGTCGATGCTCTTCCGCCAGACGCCGGCGGAGGTCCGCATG
ATCATGGTGGACCCGAAGATGACCGAGCTGTCCACCTACGAGGACATCCCGCACCTGCTGCTGCCGGTGGTCACCGACCC
GCAGAAGGCGGCGCGCGCGCTGCAGTGGGCCGTGGACGAGATGGAGCGGCGCACGCAGATCCTCGCCGACACCGGCTCGA
AGGACCTCAAGTCGTACAACGGCAAGGTGGAGAAGCTGCGCACCGAGGGCCGCACCTTCGAGGACCGCGACGAGGCCGCG
CCGCCCCGCAAGCTGGTGGTGGTGGACGTGGCCGCGGGCGAGTCGGAGGACGAGGTCTCGGCTCGCGCCGCGAGCGACGC
GGCCGCCGGCGGCGGGTGGCACCCGCTGCCCGGCGAGGCGGTGGCGGGCTCGCCCGAGTTCGAGGACCCCACCGCGCCGC
CGCCCGCCGACCCGGTGGCCGCGCGCGACGAGAAGAAGCTGCCGCAGAAGCTGCCGTACATCGTGGTGGTGATCGACGAG
CTGGCCGACCTCATGATGACCGCGCCGCGCGAGGTGGAGATCTCGCTCGCGCGCCTCGCGCAGAAGGCCCGCGCCACCGG
CATCCACCTCATCGTCGCCACGCAGCGCCCGTCCACCGACGTGGTCACGGGCATGATCAAGAACAACTTCCCCGCGCGCA
TCACGTTCCGGCTCGCCTCGCGCCACGACTCGCAGACCATCATCAACGGCCCCGGCGCCGAGACGCTGCTCGGCGACGGC
GACATGCTGGTGCTCACCGCCACCGCGCCGGTGACCCGCGTGCAGGGCGCGTTCGTCTCCGAGGAGGAGCTGCACCGGGT
GGTCGGCTTCCTGAAGGAGCAGGGCAAGCCGGTCTACGACGAGTCGATCCTGAAGGCGCGCGAGGGCGCCGGCCCGGGCG
GCTACGATCCCGACGAGGACGACCCGGTGTACGACCAGGCCATCGACCTCGTCTCGCGCATGGAGGAGGTCTCGGTCTCG
AAGCTCCAGCGCGAGATGCGCCTCGGCTACAACAAGGCCGCGAAGATCATCGAGCGCATGGAGCGCGAGGGCATCGTCGG
CCCGCCGAACGGCGTGAAGCCGCGCCAGGTGCTGATCCGCCCCGCCGGCGAGACCAGCGCGATCCCGAACGTCTGA

Upstream 100 bases:

>100_bases
CGCCGAAAAATTGACCCCCCGGTACCCCCCGATATCCTCCCGGAGGCAGGCCCTCGTCCGCGCGAGCGGCGTGTTCCACC
CTCGAGGTCCCGTCGTCGCC

Downstream 100 bases:

>100_bases
TCCCGCGCGCCCGCGGCGCATCGCCCGTCCGTTCTCGCGCGCACGCACCGGCGCACGTTCTCCTACATCGGTGCCGGTGG
ATTTCCCTTCCGCGATGCCC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 931; Mature: 930

Protein sequence:

>931_residues
MGKPKANRRVSPKEKGKRGDPPAERAKGGAAPRTGMARDVGAVVLFAAALGSGLSLATYSSLDAALIAHGIAPANLVGPV
GHRTASALYGVLGLSALVLPFGLGAAAWRLFRGAPPRITLVSAGAYTVLTLSVATLGHLALAGSVSLPFPPGGAVGAALA
RPSVHAFSLWGSVILVGATATVAAIVACDLKVQTVGAALWRALAATAGFLSRRLATAVDEHRVAVAELRAEEAAERERRL
AAEQLAETAEIEANGEEAHEEARAVAGALALEQLRRDTFEDPAWVEGLAPAPEPREEAEGAGEGEPAAEEPPRRRRKARE
PEKAVDVRAELEDPAALPVPARAEKPEIVVSQAMLERARKKEKKKEAPAFAFQKAGDVFQLPATDLLDVHDEKAKDLDTA
GLTRTAEVIVATLAQHGVDGTIKHIRPGPVVTLYEFSPVAGVKLARIENLDKELTMALSATRIRIIAPIPGKGVVGIEVP
NRDRATVWLRDILESESFASAGGFLPLGLGKNIEGIPYCVDLQRMPHLLIAGTTGSGKSVGLNTMILSMLFRQTPAEVRM
IMVDPKMTELSTYEDIPHLLLPVVTDPQKAARALQWAVDEMERRTQILADTGSKDLKSYNGKVEKLRTEGRTFEDRDEAA
PPRKLVVVDVAAGESEDEVSARAASDAAAGGGWHPLPGEAVAGSPEFEDPTAPPPADPVAARDEKKLPQKLPYIVVVIDE
LADLMMTAPREVEISLARLAQKARATGIHLIVATQRPSTDVVTGMIKNNFPARITFRLASRHDSQTIINGPGAETLLGDG
DMLVLTATAPVTRVQGAFVSEEELHRVVGFLKEQGKPVYDESILKAREGAGPGGYDPDEDDPVYDQAIDLVSRMEEVSVS
KLQREMRLGYNKAAKIIERMEREGIVGPPNGVKPRQVLIRPAGETSAIPNV

Sequences:

>Translated_931_residues
MGKPKANRRVSPKEKGKRGDPPAERAKGGAAPRTGMARDVGAVVLFAAALGSGLSLATYSSLDAALIAHGIAPANLVGPV
GHRTASALYGVLGLSALVLPFGLGAAAWRLFRGAPPRITLVSAGAYTVLTLSVATLGHLALAGSVSLPFPPGGAVGAALA
RPSVHAFSLWGSVILVGATATVAAIVACDLKVQTVGAALWRALAATAGFLSRRLATAVDEHRVAVAELRAEEAAERERRL
AAEQLAETAEIEANGEEAHEEARAVAGALALEQLRRDTFEDPAWVEGLAPAPEPREEAEGAGEGEPAAEEPPRRRRKARE
PEKAVDVRAELEDPAALPVPARAEKPEIVVSQAMLERARKKEKKKEAPAFAFQKAGDVFQLPATDLLDVHDEKAKDLDTA
GLTRTAEVIVATLAQHGVDGTIKHIRPGPVVTLYEFSPVAGVKLARIENLDKELTMALSATRIRIIAPIPGKGVVGIEVP
NRDRATVWLRDILESESFASAGGFLPLGLGKNIEGIPYCVDLQRMPHLLIAGTTGSGKSVGLNTMILSMLFRQTPAEVRM
IMVDPKMTELSTYEDIPHLLLPVVTDPQKAARALQWAVDEMERRTQILADTGSKDLKSYNGKVEKLRTEGRTFEDRDEAA
PPRKLVVVDVAAGESEDEVSARAASDAAAGGGWHPLPGEAVAGSPEFEDPTAPPPADPVAARDEKKLPQKLPYIVVVIDE
LADLMMTAPREVEISLARLAQKARATGIHLIVATQRPSTDVVTGMIKNNFPARITFRLASRHDSQTIINGPGAETLLGDG
DMLVLTATAPVTRVQGAFVSEEELHRVVGFLKEQGKPVYDESILKAREGAGPGGYDPDEDDPVYDQAIDLVSRMEEVSVS
KLQREMRLGYNKAAKIIERMEREGIVGPPNGVKPRQVLIRPAGETSAIPNV
>Mature_930_residues
GKPKANRRVSPKEKGKRGDPPAERAKGGAAPRTGMARDVGAVVLFAAALGSGLSLATYSSLDAALIAHGIAPANLVGPVG
HRTASALYGVLGLSALVLPFGLGAAAWRLFRGAPPRITLVSAGAYTVLTLSVATLGHLALAGSVSLPFPPGGAVGAALAR
PSVHAFSLWGSVILVGATATVAAIVACDLKVQTVGAALWRALAATAGFLSRRLATAVDEHRVAVAELRAEEAAERERRLA
AEQLAETAEIEANGEEAHEEARAVAGALALEQLRRDTFEDPAWVEGLAPAPEPREEAEGAGEGEPAAEEPPRRRRKAREP
EKAVDVRAELEDPAALPVPARAEKPEIVVSQAMLERARKKEKKKEAPAFAFQKAGDVFQLPATDLLDVHDEKAKDLDTAG
LTRTAEVIVATLAQHGVDGTIKHIRPGPVVTLYEFSPVAGVKLARIENLDKELTMALSATRIRIIAPIPGKGVVGIEVPN
RDRATVWLRDILESESFASAGGFLPLGLGKNIEGIPYCVDLQRMPHLLIAGTTGSGKSVGLNTMILSMLFRQTPAEVRMI
MVDPKMTELSTYEDIPHLLLPVVTDPQKAARALQWAVDEMERRTQILADTGSKDLKSYNGKVEKLRTEGRTFEDRDEAAP
PRKLVVVDVAAGESEDEVSARAASDAAAGGGWHPLPGEAVAGSPEFEDPTAPPPADPVAARDEKKLPQKLPYIVVVIDEL
ADLMMTAPREVEISLARLAQKARATGIHLIVATQRPSTDVVTGMIKNNFPARITFRLASRHDSQTIINGPGAETLLGDGD
MLVLTATAPVTRVQGAFVSEEELHRVVGFLKEQGKPVYDESILKAREGAGPGGYDPDEDDPVYDQAIDLVSRMEEVSVSK
LQREMRLGYNKAAKIIERMEREGIVGPPNGVKPRQVLIRPAGETSAIPNV

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=546, Percent_Identity=39.7435897435897, Blast_Score=340, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 99033; Mature: 98902

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPKANRRVSPKEKGKRGDPPAERAKGGAAPRTGMARDVGAVVLFAAALGSGLSLATYS
CCCCCCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHH
SLDAALIAHGIAPANLVGPVGHRTASALYGVLGLSALVLPFGLGAAAWRLFRGAPPRITL
HHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEE
VSAGAYTVLTLSVATLGHLALAGSVSLPFPPGGAVGAALARPSVHAFSLWGSVILVGATA
EECCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHEECHHH
TVAAIVACDLKVQTVGAALWRALAATAGFLSRRLATAVDEHRVAVAELRAEEAAERERRL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEQLAETAEIEANGEEAHEEARAVAGALALEQLRRDTFEDPAWVEGLAPAPEPREEAEG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHCC
AGEGEPAAEEPPRRRRKAREPEKAVDVRAELEDPAALPVPARAEKPEIVVSQAMLERARK
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KEKKKEAPAFAFQKAGDVFQLPATDLLDVHDEKAKDLDTAGLTRTAEVIVATLAQHGVDG
HHHHHCCCHHHHHHCCCEEECCCHHHHHCCCHHHHCCCHHCCHHHHHHHHHHHHHCCCCC
TIKHIRPGPVVTLYEFSPVAGVKLARIENLDKELTMALSATRIRIIAPIPGKGVVGIEVP
CEEECCCCCEEEEEECCCCCCEEHHHHHCCHHHHHHHHEECEEEEEEECCCCCEEEEECC
NRDRATVWLRDILESESFASAGGFLPLGLGKNIEGIPYCVDLQRMPHLLIAGTTGSGKSV
CCCCHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCEEEEHHHCCEEEEEECCCCCCCC
GLNTMILSMLFRQTPAEVRMIMVDPKMTELSTYEDIPHLLLPVVTDPQKAARALQWAVDE
CHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHH
MERRTQILADTGSKDLKSYNGKVEKLRTEGRTFEDRDEAAPPRKLVVVDVAAGESEDEVS
HHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHH
ARAASDAAAGGGWHPLPGEAVAGSPEFEDPTAPPPADPVAARDEKKLPQKLPYIVVVIDE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHCCEEEEEHHH
LADLMMTAPREVEISLARLAQKARATGIHLIVATQRPSTDVVTGMIKNNFPARITFRLAS
HHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEEEC
RHDSQTIINGPGAETLLGDGDMLVLTATAPVTRVQGAFVSEEELHRVVGFLKEQGKPVYD
CCCCCEEECCCCCCCEECCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCHH
ESILKAREGAGPGGYDPDEDDPVYDQAIDLVSRMEEVSVSKLQREMRLGYNKAAKIIERM
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EREGIVGPPNGVKPRQVLIRPAGETSAIPNV
HHCCCCCCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GKPKANRRVSPKEKGKRGDPPAERAKGGAAPRTGMARDVGAVVLFAAALGSGLSLATYS
CCCCCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHH
SLDAALIAHGIAPANLVGPVGHRTASALYGVLGLSALVLPFGLGAAAWRLFRGAPPRITL
HHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEE
VSAGAYTVLTLSVATLGHLALAGSVSLPFPPGGAVGAALARPSVHAFSLWGSVILVGATA
EECCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHEECHHH
TVAAIVACDLKVQTVGAALWRALAATAGFLSRRLATAVDEHRVAVAELRAEEAAERERRL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEQLAETAEIEANGEEAHEEARAVAGALALEQLRRDTFEDPAWVEGLAPAPEPREEAEG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHCC
AGEGEPAAEEPPRRRRKAREPEKAVDVRAELEDPAALPVPARAEKPEIVVSQAMLERARK
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KEKKKEAPAFAFQKAGDVFQLPATDLLDVHDEKAKDLDTAGLTRTAEVIVATLAQHGVDG
HHHHHCCCHHHHHHCCCEEECCCHHHHHCCCHHHHCCCHHCCHHHHHHHHHHHHHCCCCC
TIKHIRPGPVVTLYEFSPVAGVKLARIENLDKELTMALSATRIRIIAPIPGKGVVGIEVP
CEEECCCCCEEEEEECCCCCCEEHHHHHCCHHHHHHHHEECEEEEEEECCCCCEEEEECC
NRDRATVWLRDILESESFASAGGFLPLGLGKNIEGIPYCVDLQRMPHLLIAGTTGSGKSV
CCCCHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCEEEEHHHCCEEEEEECCCCCCCC
GLNTMILSMLFRQTPAEVRMIMVDPKMTELSTYEDIPHLLLPVVTDPQKAARALQWAVDE
CHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHH
MERRTQILADTGSKDLKSYNGKVEKLRTEGRTFEDRDEAAPPRKLVVVDVAAGESEDEVS
HHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHH
ARAASDAAAGGGWHPLPGEAVAGSPEFEDPTAPPPADPVAARDEKKLPQKLPYIVVVIDE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHCCEEEEEHHH
LADLMMTAPREVEISLARLAQKARATGIHLIVATQRPSTDVVTGMIKNNFPARITFRLAS
HHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEEEC
RHDSQTIINGPGAETLLGDGDMLVLTATAPVTRVQGAFVSEEELHRVVGFLKEQGKPVYD
CCCCCEEECCCCCCCEECCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCHH
ESILKAREGAGPGGYDPDEDDPVYDQAIDLVSRMEEVSVSKLQREMRLGYNKAAKIIERM
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EREGIVGPPNGVKPRQVLIRPAGETSAIPNV
HHCCCCCCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]