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The map label for this gene is wecB [H]

Identifier: 220919408

GI number: 220919408

Start: 4821956

End: 4823059

Strand: Direct

Name: wecB [H]

Synonym: A2cp1_4329

Alternate gene names: 220919408

Gene position: 4821956-4823059 (Clockwise)

Preceding gene: 220919390

Following gene: 220919409

Centisome position: 95.88

GC content: 77.17

Gene sequence:

>1104_bases
ATGGCCCTCGTGCTCCACGTGGTCGGCGCCCGTCCCAACTTCATGAAGGTCGCACCCCTGATGGCGGCGCTCTCCCGGCG
GGGCGCTGCGCAGCGGCTGGTCCACACCGGCCAGCACTTCGACGAGCGGATGAGCGGGGTGTTCTTCGCCGAGCTCGGGC
TGCCCCGCCCCGACCTCGACCTGGGGGTGGGCTCCGGCACCCACGGCGAGCAGACGGGCCGGGTGATGATCGCGTTCGAG
CGGGCGCTGCTCGAGGCGGCGCCGCGGCCGGACCTGGTGGTCGTGCCCGGCGACGTGAACTCGACCGTGGCGGCCGCGCT
GGTGGCGGCGAAGCTCGGGATCCCGGTGGCGCACCTCGAGGCGGGCCTGCGCAGCTTCGACCGGACCATGCCGGAGGAGC
TGAACCGGGTGGTCACCGATCACCTCTCGGACCTGCTGCTCACCCCGAGCCCCGACGCCGACGAGAACCTCGCGCGCGAG
GGGATCCCGGCCACGCGCGTGGCGCGGGTCGGGAACCTCATGATCGACACGCTCCGCGCCCACCTTCCGCGCGCCCGCGC
GCTCGCGGCCTGGCGCGGCCTGGGCCTCCCCGAGGGCGGCTACGCCGTCGTCACGCTGCACCGGCCCTCCAACGTGGACG
ATCCCGCCGGCCTGGGGCGGCTGCTCGGCGCGCTGGCGGAGGTCGCGCGCGCGCTGCCGGTGGTGTTCCCGGTCCACCCG
CGCACCCGCGCCCGCCTCGCCGACCCCGCGCTGGCCGGGGCCGCCGCCGCGCTGCGCCTGGTCGAGCCGCTCGGCTACCT
CGAGTTCCTCTCGCTCACCAGCGCCGCGCGCCTGGTGCTCACCGACTCCGGCGGCCTGCAGGAGGAGTCCACCGCGCTCG
GCGTCCCGTGCCTCACGCTGCGCGAGAACACCGAGCGCCCCATCACCGTGGCCGAGGGGACGAACCACGTGGTGGGCACC
GACCCCGCGCGCATCGCGGCGGAGGCCCGCCGCGCGCTCGACGCCGGCCCGGGACGCGGCCGCACCCCGGCGCTCTGGGA
CGGGCAGGCGGGGGAGCGGGCCGCGGACGCGGTGCTCGCGTTCCTGGCCGGCGCGCGGGCCTGA

Upstream 100 bases:

>100_bases
AGGTCCCCGCGGGCGCGCCCGGCGGCGCGCGGGCCGCCGGGGCAGCGCCGGTGCGCGCGCGGGTCATTTCGGGGGAGCGC
CGGGCCGCCTAGCTTTCGAC

Downstream 100 bases:

>100_bases
CCGGCGCCTCGCGGGGACGGGGGCGCGGCGGCGGCGCCCGGTGTATGGTGCGCCGGTGACGCAGCAGGTCCGGGTCCGCT
TCACGGTCGAGCCGAACTAC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MALVLHVVGARPNFMKVAPLMAALSRRGAAQRLVHTGQHFDERMSGVFFAELGLPRPDLDLGVGSGTHGEQTGRVMIAFE
RALLEAAPRPDLVVVPGDVNSTVAAALVAAKLGIPVAHLEAGLRSFDRTMPEELNRVVTDHLSDLLLTPSPDADENLARE
GIPATRVARVGNLMIDTLRAHLPRARALAAWRGLGLPEGGYAVVTLHRPSNVDDPAGLGRLLGALAEVARALPVVFPVHP
RTRARLADPALAGAAAALRLVEPLGYLEFLSLTSAARLVLTDSGGLQEESTALGVPCLTLRENTERPITVAEGTNHVVGT
DPARIAAEARRALDAGPGRGRTPALWDGQAGERAADAVLAFLAGARA

Sequences:

>Translated_367_residues
MALVLHVVGARPNFMKVAPLMAALSRRGAAQRLVHTGQHFDERMSGVFFAELGLPRPDLDLGVGSGTHGEQTGRVMIAFE
RALLEAAPRPDLVVVPGDVNSTVAAALVAAKLGIPVAHLEAGLRSFDRTMPEELNRVVTDHLSDLLLTPSPDADENLARE
GIPATRVARVGNLMIDTLRAHLPRARALAAWRGLGLPEGGYAVVTLHRPSNVDDPAGLGRLLGALAEVARALPVVFPVHP
RTRARLADPALAGAAAALRLVEPLGYLEFLSLTSAARLVLTDSGGLQEESTALGVPCLTLRENTERPITVAEGTNHVVGT
DPARIAAEARRALDAGPGRGRTPALWDGQAGERAADAVLAFLAGARA
>Mature_366_residues
ALVLHVVGARPNFMKVAPLMAALSRRGAAQRLVHTGQHFDERMSGVFFAELGLPRPDLDLGVGSGTHGEQTGRVMIAFER
ALLEAAPRPDLVVVPGDVNSTVAAALVAAKLGIPVAHLEAGLRSFDRTMPEELNRVVTDHLSDLLLTPSPDADENLAREG
IPATRVARVGNLMIDTLRAHLPRARALAAWRGLGLPEGGYAVVTLHRPSNVDDPAGLGRLLGALAEVARALPVVFPVHPR
TRARLADPALAGAAAALRLVEPLGYLEFLSLTSAARLVLTDSGGLQEESTALGVPCLTLRENTERPITVAEGTNHVVGTD
PARIAAEARRALDAGPGRGRTPALWDGQAGERAADAVLAFLAGARA

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=375, Percent_Identity=35.4666666666667, Blast_Score=157, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 38525; Mature: 38394

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVLHVVGARPNFMKVAPLMAALSRRGAAQRLVHTGQHFDERMSGVFFAELGLPRPDLD
CEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LGVGSGTHGEQTGRVMIAFERALLEAAPRPDLVVVPGDVNSTVAAALVAAKLGIPVAHLE
CCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHH
AGLRSFDRTMPEELNRVVTDHLSDLLLTPSPDADENLAREGIPATRVARVGNLMIDTLRA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
HLPRARALAAWRGLGLPEGGYAVVTLHRPSNVDDPAGLGRLLGALAEVARALPVVFPVHP
HCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEECCCC
RTRARLADPALAGAAAALRLVEPLGYLEFLSLTSAARLVLTDSGGLQEESTALGVPCLTL
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEEEE
RENTERPITVAEGTNHVVGTDPARIAAEARRALDAGPGRGRTPALWDGQAGERAADAVLA
CCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
FLAGARA
HHHCCCC
>Mature Secondary Structure 
ALVLHVVGARPNFMKVAPLMAALSRRGAAQRLVHTGQHFDERMSGVFFAELGLPRPDLD
EEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LGVGSGTHGEQTGRVMIAFERALLEAAPRPDLVVVPGDVNSTVAAALVAAKLGIPVAHLE
CCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHH
AGLRSFDRTMPEELNRVVTDHLSDLLLTPSPDADENLAREGIPATRVARVGNLMIDTLRA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
HLPRARALAAWRGLGLPEGGYAVVTLHRPSNVDDPAGLGRLLGALAEVARALPVVFPVHP
HCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEECCCC
RTRARLADPALAGAAAALRLVEPLGYLEFLSLTSAARLVLTDSGGLQEESTALGVPCLTL
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEEEE
RENTERPITVAEGTNHVVGTDPARIAAEARRALDAGPGRGRTPALWDGQAGERAADAVLA
CCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
FLAGARA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]