Click here to switch to the map view.

The map label for this gene is oprJ [H]

Identifier: 220919385

GI number: 220919385

Start: 4797535

End: 4798878

Strand: Direct

Name: oprJ [H]

Synonym: A2cp1_4306

Alternate gene names: 220919385

Gene position: 4797535-4798878 (Clockwise)

Preceding gene: 220919384

Following gene: 220919386

Centisome position: 95.39

GC content: 76.49

Gene sequence:

>1344_bases
ATGCGCTCCCTCGCCGCCGCGCTCCTCCTCGCCCTCGCCTCCGCGACGCGCGCCCAGGCCCCCATCACGCTCGACGACGC
GCTCGCGCAGGCCGCGCGCGCCAACGCCGACCTCTCCATGGCGCGCGCCGACCGCGGCATGGCCGCCGCCGACCGCGGCC
AGGCGCGCGCCGCGGTGCTGCCGCGCCTCGACCTCGACGCCGGGTTCGGCCACAGCTTCATCGGCCGCGCCTCCGGCGCC
GGAGCGCTCATCGACCCGATCACCGGGCAGGTGACCGTGATCGGCGTCGCGAGCGACTCCGAGGCCTACAGCGCCTCGCT
CTCGCTCTCGCAGCCGCTCTTCGACTGGGCCCGCTTCAAGGACCTCGACCGCGCCCGCTGGGGCGCCCGCGCCAGCGACC
GCGGCTACGACGAGACCGCGCTGTCCGTCTCCTTCGAGGTCACCCGCCGCTTCTACGACCTCGTGAAGCAGGAGCGGAGC
CTCGAGGTGCTGCAGAAGACCGTGACGCGCTCGCAGGAGCTGGTGGACCGCGCCGAGGCGCTGTTCACCGCCGGCCGCGC
GCCGAAGAGCGACACCTACTCGGCCCGCGTGAACCTGCAGAACGACCGGATCGCGGTGGAGGGGCAGCACATCCGCGTGG
CGCAGGCCCGCACCGCGCTCGCCCAGGTGCTCGGGCGCATCGACGCCGAGGCGATCTCGGTGGTGGCGCCCGCGGCGATC
GACGCGCCCGGCGTCCCCGGCGCCGAGCCTCCCCCGGCCGACGCGCTCCTCGCCCGCGCCCGCGAGCGCCGCCCGGCGGT
GCTGGCCCAGGCGGCCTCGGTGCACGCGGCCCGCGCCGGGGTCGGCGGCGCGCAGGCGGGCTACCTGCCCACGGTCTCGG
CGGTGGGCTCCTACGCGCGGCAGGGCACGGTGCTCGGCGGCCAGGGCGGCGTCTACGGCGACCCCTCGCGCGACTACAGC
GCCTCCGCCCAGGTGGTCCTCTCCTGGAACCTGTTCGAGGGGTTCGGCACCTCCGCCCGCGTGCAGCGCGCCTCGGCCTC
GCTCGACCGCGCCCGCGCCGACGAGGACCGCACGCTCCAGGCGGTCGCGAAGGAGATCGGCGACGCGCGGGCGGCGACGG
TGGCGCTCGCCCGGCAGGTGGCGCTCGCCACCGACACGCTCACCATCGCGCAACAGTCCCTGGCGCTCGCCACCGAGCGG
CTGGAGGCGGGCCTCGCCAACCAGCTCGAGCTCCGCGACGCCAATCTCAAGCTGACGCAGGCGGAGCTCTCGCTCCTCGA
GTCCCGCATCGATCACGCCGTGGCGGTCGCCGACCTGGCGCGCGCCGCGGGAGGAACGCTCTAG

Upstream 100 bases:

>100_bases
CTGGTGCTCTTCGCCGCCTACGTGGCGCTCTTCCAGGTGGTCCCCGCCGCGCTGTCGGCGGGCGGCCCCGGCCCCCGCTA
GCACAAGGACCCGAGACCGC

Downstream 100 bases:

>100_bases
ATGGCCACGCAGAACCCGCTCCCGATGCCCTCCCCCGACCACGCTGCCCCGGCCCCGGACGCCCCGGTGCTCGCCGCCCT
CCCGCCGCAGCCGCGCATGA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MRSLAAALLLALASATRAQAPITLDDALAQAARANADLSMARADRGMAAADRGQARAAVLPRLDLDAGFGHSFIGRASGA
GALIDPITGQVTVIGVASDSEAYSASLSLSQPLFDWARFKDLDRARWGARASDRGYDETALSVSFEVTRRFYDLVKQERS
LEVLQKTVTRSQELVDRAEALFTAGRAPKSDTYSARVNLQNDRIAVEGQHIRVAQARTALAQVLGRIDAEAISVVAPAAI
DAPGVPGAEPPPADALLARARERRPAVLAQAASVHAARAGVGGAQAGYLPTVSAVGSYARQGTVLGGQGGVYGDPSRDYS
ASAQVVLSWNLFEGFGTSARVQRASASLDRARADEDRTLQAVAKEIGDARAATVALARQVALATDTLTIAQQSLALATER
LEAGLANQLELRDANLKLTQAELSLLESRIDHAVAVADLARAAGGTL

Sequences:

>Translated_447_residues
MRSLAAALLLALASATRAQAPITLDDALAQAARANADLSMARADRGMAAADRGQARAAVLPRLDLDAGFGHSFIGRASGA
GALIDPITGQVTVIGVASDSEAYSASLSLSQPLFDWARFKDLDRARWGARASDRGYDETALSVSFEVTRRFYDLVKQERS
LEVLQKTVTRSQELVDRAEALFTAGRAPKSDTYSARVNLQNDRIAVEGQHIRVAQARTALAQVLGRIDAEAISVVAPAAI
DAPGVPGAEPPPADALLARARERRPAVLAQAASVHAARAGVGGAQAGYLPTVSAVGSYARQGTVLGGQGGVYGDPSRDYS
ASAQVVLSWNLFEGFGTSARVQRASASLDRARADEDRTLQAVAKEIGDARAATVALARQVALATDTLTIAQQSLALATER
LEAGLANQLELRDANLKLTQAELSLLESRIDHAVAVADLARAAGGTL
>Mature_447_residues
MRSLAAALLLALASATRAQAPITLDDALAQAARANADLSMARADRGMAAADRGQARAAVLPRLDLDAGFGHSFIGRASGA
GALIDPITGQVTVIGVASDSEAYSASLSLSQPLFDWARFKDLDRARWGARASDRGYDETALSVSFEVTRRFYDLVKQERS
LEVLQKTVTRSQELVDRAEALFTAGRAPKSDTYSARVNLQNDRIAVEGQHIRVAQARTALAQVLGRIDAEAISVVAPAAI
DAPGVPGAEPPPADALLARARERRPAVLAQAASVHAARAGVGGAQAGYLPTVSAVGSYARQGTVLGGQGGVYGDPSRDYS
ASAQVVLSWNLFEGFGTSARVQRASASLDRARADEDRTLQAVAKEIGDARAATVALARQVALATDTLTIAQQSLALATER
LEAGLANQLELRDANLKLTQAELSLLESRIDHAVAVADLARAAGGTL

Specific function: Channel-forming component of a multidrug resistance efflux pump [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=437, Percent_Identity=22.4256292906178, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 46722; Mature: 46722

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLAAALLLALASATRAQAPITLDDALAQAARANADLSMARADRGMAAADRGQARAAVL
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHCCCCCCCCCC
PRLDLDAGFGHSFIGRASGAGALIDPITGQVTVIGVASDSEAYSASLSLSQPLFDWARFK
CCCCCCCCCCCHHHCCCCCCCCEECCCCCCEEEEEEECCCCHHEEECCCCCHHHHHHHHH
DLDRARWGARASDRGYDETALSVSFEVTRRFYDLVKQERSLEVLQKTVTRSQELVDRAEA
HHHHHHCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFTAGRAPKSDTYSARVNLQNDRIAVEGQHIRVAQARTALAQVLGRIDAEAISVVAPAAI
HHHCCCCCCCCCEEEEEEECCCEEEECCCEEEHHHHHHHHHHHHHHCCHHHHHHCCCCCC
DAPGVPGAEPPPADALLARARERRPAVLAQAASVHAARAGVGGAQAGYLPTVSAVGSYAR
CCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
QGTVLGGQGGVYGDPSRDYSASAQVVLSWNLFEGFGTSARVQRASASLDRARADEDRTLQ
CCCEECCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHH
AVAKEIGDARAATVALARQVALATDTLTIAQQSLALATERLEAGLANQLELRDANLKLTQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHH
AELSLLESRIDHAVAVADLARAAGGTL
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSLAAALLLALASATRAQAPITLDDALAQAARANADLSMARADRGMAAADRGQARAAVL
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHCCCCCCCCCC
PRLDLDAGFGHSFIGRASGAGALIDPITGQVTVIGVASDSEAYSASLSLSQPLFDWARFK
CCCCCCCCCCCHHHCCCCCCCCEECCCCCCEEEEEEECCCCHHEEECCCCCHHHHHHHHH
DLDRARWGARASDRGYDETALSVSFEVTRRFYDLVKQERSLEVLQKTVTRSQELVDRAEA
HHHHHHCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFTAGRAPKSDTYSARVNLQNDRIAVEGQHIRVAQARTALAQVLGRIDAEAISVVAPAAI
HHHCCCCCCCCCEEEEEEECCCEEEECCCEEEHHHHHHHHHHHHHHCCHHHHHHCCCCCC
DAPGVPGAEPPPADALLARARERRPAVLAQAASVHAARAGVGGAQAGYLPTVSAVGSYAR
CCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
QGTVLGGQGGVYGDPSRDYSASAQVVLSWNLFEGFGTSARVQRASASLDRARADEDRTLQ
CCCEECCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHH
AVAKEIGDARAATVALARQVALATDTLTIAQQSLALATERLEAGLANQLELRDANLKLTQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHH
AELSLLESRIDHAVAVADLARAAGGTL
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8878035; 10984043 [H]