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The map label for this gene is trpB1 [H]

Identifier: 220919279

GI number: 220919279

Start: 4685896

End: 4687200

Strand: Direct

Name: trpB1 [H]

Synonym: A2cp1_4200

Alternate gene names: 220919279

Gene position: 4685896-4687200 (Clockwise)

Preceding gene: 220919278

Following gene: 220919280

Centisome position: 93.17

GC content: 75.25

Gene sequence:

>1305_bases
GTGAAGACGGCAGCCCTCCCCGACGAGCGGGGGCGCTTCGGCGCCTTCGGCGGGCGCTTCGTGCCCGAGACCCTGGTGCC
GGCGCTGGACGAGCTCGAGCAGGCCTGGCGCGAGGCGCGGGCCGACCCCGCCTTCCAGGCGGAGCTGGACGAGCTGCTCC
GGCGCTACGCCGGGCGCGAGACGCCGATCTCCGAGGCGCCGCGCATGAGCGCCGACGTGGGCGGGTGCCGCGTGCTCCTG
AAGCGCGAGGACCTGTGCCACACCGGCTCGCACAAGCTCAACAACACGCTCGGCCAGATCCTGCTCGCCCGCCGCATGGG
CAAGAAGCGGATCATCGCCGAGACCGGCGCCGGCCAGCACGGCGTCGCCACCGCCACCGCGGCGGCGCTGTTCGGCCTGC
CCTGCGAGGTCTACCAGGGCGCGGTGGACGTGGAGCGGCAGGCGCTCAACGTCTTCCGGATGCAGCTCCTCGGCGCGCGG
GTCATCCCGGTGACGGCCGGCTCCGCCACGCTGAAGGACGCGATGAACGAGGCGCTGCGCGACTGGGTCACCAACGTCCG
CGACACGCACTACATCATCGGCTCGGTGGCCGGCCCGCACCCCTACCCGGCCATGGTCCGCACGTTCCAGTCGGTGATCG
GGCGCGAGGCGCGCCGGCAGGTGCTGGAGCTGGCCGGCCGGCTGCCCGACGCGGTGGTCGCCTGCGTGGGCGGCGGCTCC
AACGCCATGGGCATCTTCTCGGCGTTCGTGGACGACGCGCACGTGGACCTGGTGGCCGCCGAGGCCGCCGGCCTCGGGCT
CTCGACCGCGAAGCACGGCGCCTCGCTGGCGAAGGGGACCCCGGGCGTGCTGCACGGCTCGCGGAGCTACGTGCTCCAGG
ACGGGCACGGGCAGATCCAGGAGGCGCACTCGATCAGCGCCGGCCTCGACTACCCGGGCGTCGGGCCGGAGCTCTCCTAC
CTGAAGGACCAGGGCCGGCTCACGCTGCTGCCGCAGACCGACGCCGAGGCGCTGGACGCGTTCCAGTACCTCGCGCGCAT
GGAGGGGATCATCCCCGCGCTGGAGAGCGCGCACGCGGTCTCGGCCGCGCGCAAGGTGGCCCGCGACGCCGGGCCGGGAG
GGCTGGTGCTCGTGAACGTCTCCGGGCGCGGCGACAAGGACGTGGAGCAGGTGCGGAAGATGCTCGAGGCGGCCCCGCCG
CCGCGGCGCAGCCGCGCCCGCCCGGCACGGCCGGCGCGGCCGAAGGGCAAGGCGAAGGCCGAGGCGAGGCCGCGCGCCGC
GGCGCGGAAGGGAGGCCGCCGGTGA

Upstream 100 bases:

>100_bases
GGCCCTGGGCGGTGGACGTGGCGAGCGGCGTCGAGTCGGCGCCCGGCGTGAAGGATCGGCAGCTCATGGCGCGGTTCGTC
CGCGCGGCAAAGGAGACGAC

Downstream 100 bases:

>100_bases
GCCCGCGCCCCGCCCGCAAGCCCCGCGCCGCCGCCGCGCCCGTCGCGGCCGAGCGCCCCGACCGCATCTCGGCCGCGTTC
GAGCGCTGCCGCGCCGAGCG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKTAALPDERGRFGAFGGRFVPETLVPALDELEQAWREARADPAFQAELDELLRRYAGRETPISEAPRMSADVGGCRVLL
KREDLCHTGSHKLNNTLGQILLARRMGKKRIIAETGAGQHGVATATAAALFGLPCEVYQGAVDVERQALNVFRMQLLGAR
VIPVTAGSATLKDAMNEALRDWVTNVRDTHYIIGSVAGPHPYPAMVRTFQSVIGREARRQVLELAGRLPDAVVACVGGGS
NAMGIFSAFVDDAHVDLVAAEAAGLGLSTAKHGASLAKGTPGVLHGSRSYVLQDGHGQIQEAHSISAGLDYPGVGPELSY
LKDQGRLTLLPQTDAEALDAFQYLARMEGIIPALESAHAVSAARKVARDAGPGGLVLVNVSGRGDKDVEQVRKMLEAAPP
PRRSRARPARPARPKGKAKAEARPRAAARKGGRR

Sequences:

>Translated_434_residues
MKTAALPDERGRFGAFGGRFVPETLVPALDELEQAWREARADPAFQAELDELLRRYAGRETPISEAPRMSADVGGCRVLL
KREDLCHTGSHKLNNTLGQILLARRMGKKRIIAETGAGQHGVATATAAALFGLPCEVYQGAVDVERQALNVFRMQLLGAR
VIPVTAGSATLKDAMNEALRDWVTNVRDTHYIIGSVAGPHPYPAMVRTFQSVIGREARRQVLELAGRLPDAVVACVGGGS
NAMGIFSAFVDDAHVDLVAAEAAGLGLSTAKHGASLAKGTPGVLHGSRSYVLQDGHGQIQEAHSISAGLDYPGVGPELSY
LKDQGRLTLLPQTDAEALDAFQYLARMEGIIPALESAHAVSAARKVARDAGPGGLVLVNVSGRGDKDVEQVRKMLEAAPP
PRRSRARPARPARPKGKAKAEARPRAAARKGGRR
>Mature_434_residues
MKTAALPDERGRFGAFGGRFVPETLVPALDELEQAWREARADPAFQAELDELLRRYAGRETPISEAPRMSADVGGCRVLL
KREDLCHTGSHKLNNTLGQILLARRMGKKRIIAETGAGQHGVATATAAALFGLPCEVYQGAVDVERQALNVFRMQLLGAR
VIPVTAGSATLKDAMNEALRDWVTNVRDTHYIIGSVAGPHPYPAMVRTFQSVIGREARRQVLELAGRLPDAVVACVGGGS
NAMGIFSAFVDDAHVDLVAAEAAGLGLSTAKHGASLAKGTPGVLHGSRSYVLQDGHGQIQEAHSISAGLDYPGVGPELSY
LKDQGRLTLLPQTDAEALDAFQYLARMEGIIPALESAHAVSAARKVARDAGPGGLVLVNVSGRGDKDVEQVRKMLEAAPP
PRRSRARPARPARPKGKAKAEARPRAAARKGGRR

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=54.6632124352332, Blast_Score=430, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321412, Length=390, Percent_Identity=56.6666666666667, Blast_Score=457, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 46172; Mature: 46172

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAALPDERGRFGAFGGRFVPETLVPALDELEQAWREARADPAFQAELDELLRRYAGRE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TPISEAPRMSADVGGCRVLLKREDLCHTGSHKLNNTLGQILLARRMGKKRIIAETGAGQH
CCCCCCCCCCCCCCHHEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEECCCCCC
GVATATAAALFGLPCEVYQGAVDVERQALNVFRMQLLGARVIPVTAGSATLKDAMNEALR
CHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHH
DWVTNVRDTHYIIGSVAGPHPYPAMVRTFQSVIGREARRQVLELAGRLPDAVVACVGGGS
HHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCC
NAMGIFSAFVDDAHVDLVAAEAAGLGLSTAKHGASLAKGTPGVLHGSRSYVLQDGHGQIQ
CHHHHHHHHHCCHHHHEEEHHHCCCCCHHHHHCCHHHCCCCCEEECCCCEEEECCCCHHH
EAHSISAGLDYPGVGPELSYLKDQGRLTLLPQTDAEALDAFQYLARMEGIIPALESAHAV
HHHHHHCCCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAARKVARDAGPGGLVLVNVSGRGDKDVEQVRKMLEAAPPPRRSRARPARPARPKGKAKA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EARPRAAARKGGRR
HCCHHHHHHCCCCC
>Mature Secondary Structure
MKTAALPDERGRFGAFGGRFVPETLVPALDELEQAWREARADPAFQAELDELLRRYAGRE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TPISEAPRMSADVGGCRVLLKREDLCHTGSHKLNNTLGQILLARRMGKKRIIAETGAGQH
CCCCCCCCCCCCCCHHEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEECCCCCC
GVATATAAALFGLPCEVYQGAVDVERQALNVFRMQLLGARVIPVTAGSATLKDAMNEALR
CHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHH
DWVTNVRDTHYIIGSVAGPHPYPAMVRTFQSVIGREARRQVLELAGRLPDAVVACVGGGS
HHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCC
NAMGIFSAFVDDAHVDLVAAEAAGLGLSTAKHGASLAKGTPGVLHGSRSYVLQDGHGQIQ
CHHHHHHHHHCCHHHHEEEHHHCCCCCHHHHHCCHHHCCCCCEEECCCCEEEECCCCHHH
EAHSISAGLDYPGVGPELSYLKDQGRLTLLPQTDAEALDAFQYLARMEGIIPALESAHAV
HHHHHHCCCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAARKVARDAGPGGLVLVNVSGRGDKDVEQVRKMLEAAPPPRRSRARPARPARPKGKAKA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EARPRAAARKGGRR
HCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]