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The map label for this gene is glmS [H]

Identifier: 220919182

GI number: 220919182

Start: 4587086

End: 4588921

Strand: Direct

Name: glmS [H]

Synonym: A2cp1_4102

Alternate gene names: 220919182

Gene position: 4587086-4588921 (Clockwise)

Preceding gene: 220919181

Following gene: 220919183

Centisome position: 91.21

GC content: 72.22

Gene sequence:

>1836_bases
ATGTGCGGAATCGTTGGTTACGTCGGCCCCCGGCAGTGCGTGGATCTCATCGTGGGTGGTCTCCGGAAGCTCGAGTACCG
TGGGTACGACTCGGCGGGCGTGGCGGTGGTCGGGCCGAACGGCCTGGCGGTGAAGCGGGCGAAGGGCAAGCTGCAGAACC
TGGTGGCGCTGCTCGCCGACGCGCCGCTCGCCGGCACGACCGGCATCGGCCACACCCGCTGGGCGACCCACGGCAAGCCC
TCGGACGAGAACGCGCACCCGCACTGCTACGGCGGGGTCGCGGTGGTCCACAACGGGATCATCGAGAACCACCTCGAGCT
GAAGGCGGCGCTGGCCGCGCGCGGCCACAAGTTCTCGTCGGAGACCGACACCGAGATCTTCGCGCACCTCATCGCGGACG
CGCTCGCCGCCGGCGCGCGCGACCTGCGCGCTGCCGTGGGCCAGGCGCTCGCGCAGGTGAAGGGCACGTACGCCATCGCG
GTGGTCTCGCAGCAGCGGCCGGAGGAGATCGTCGCCGCCAAGAACGCCTCGCCGCTGGTGGTGGGCTACGGCAAGGGCGA
GAGCTTCCTCGCCTCCGACGTGCCCGCCATCCTCGAGCACACGCGCGAGGTGGTCTACCTGGAGGAGGGCGAGCTGGCGG
TGCTCACCCCCGCCGGCATCGCGCTGTACGGGCGCGACGGCGAGCCGCTCGCGCGCAAGCCGCGCAAGATCGAGTGGAGC
GCGGTGGCCGCCGAGAAGGACGGCCACAAGCACTTCATGCACAAGGAGATCTTCGAGCAGCCGCGGGCGGTGGCAGACAC
CATCCGCGGGCGCGCCTCGCTGGAGCAGGGCGACGTGGCGCTCGACGGCATGGAGCTGCCCGCGGACTACGCCCGCTCGC
TCGAGCGGATCGTGATCGTCGCCTGCGGCACCTCCTGGCACGCCGGCCTGTCCGGGCGCCAGATGATCGAGTCGCTGGCG
CGCGTGCCGGTCGAGGTCGAGCTGGCGAGCGAGTTCCGCAACCGCGATCCGCTGGTCGACGAGCGGGTGCTGTGCCTCGC
CATCTCGCAGTCGGGCGAGACCGCCGACACGCTCGCCGCGGTGAAGATCGCCCGCGCCCGCGGCGCCCGCGCCTACGCCA
TCTGCAACGTGGTGGGCTCGGCCATCAGCCGCGAGTGCGACGGCGGCACGCTGTTCACCCGCGCCGGCCCGGAGATCGGC
GTCGCCTCGACGAAGGCGTTCACCACCCAGCTCGCCGCGCTGTTCCTCATGGCGGTCCGGCTCGGCCGGCTGCGCGGCAC
GCTGTCGCCGGAGCGCGCCCGCGAGCTGCTCGAGGACCTGCGTCGCGTGCCCTCCTGGATGGAGCAGATGATCCGCCAGG
AGGCGCAGCTCATGCCCATCGCCAAGCGCTGCGCCGCCGCGCGCGACGTGCTCTTCCTCGGCCGCGGCAGCGAGTACCCG
GTGGCGCTGGAGGGCGCGCTCAAGCTGAAGGAGATCTCGTACATCCACGCCGAGGGTTACGCCGCCGGCGAGATGAAGCA
CGGCCCCATCGCGCTCATCGACGAGGAGCTGCCGGTGGTGGTGCTGGCGACGCGCGAGCCGGCGTACGAGAAGACGCTCG
GCAACATGGAGGAGGTGCGCGCCCGCGGCGGCCAGGTGTTCGCCGTCGTGACCGAGGGCGACACGCACGCCGCCAGCCTG
GCCGAGGTGGCGATCACCGTCCCGCCCGCGCCGCCGGTGCTCGTGCCGCTCCTGTCGATCATCCCGCTCCAGTTCCTCGC
CTACCACGTGGCCGACCTGAAGGGCACCGACGTGGACCAGCCGCGGAACCTCGCGAAGAGCGTGACGGTCGAGTAG

Upstream 100 bases:

>100_bases
GGGGACGGCCACCGGCCCGGCGTCCGCCCGCAAGGGCCGCCCGGCCGCCCGGCGGGCGAGTTAGCAGCGCGCGCGCCCCG
CGTGGTATTGAGGCGACCCT

Downstream 100 bases:

>100_bases
CGCGCGGGCCCGCGCCCGCGCCGGACCTCGCGCGCGGCGCGCGGGTGCGGTAGACCTCGGCCGTGGTCACCCGCCGCCTG
TTCGTGGCCCTCGAGCCCGC

Product: glucosamine/fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MCGIVGYVGPRQCVDLIVGGLRKLEYRGYDSAGVAVVGPNGLAVKRAKGKLQNLVALLADAPLAGTTGIGHTRWATHGKP
SDENAHPHCYGGVAVVHNGIIENHLELKAALAARGHKFSSETDTEIFAHLIADALAAGARDLRAAVGQALAQVKGTYAIA
VVSQQRPEEIVAAKNASPLVVGYGKGESFLASDVPAILEHTREVVYLEEGELAVLTPAGIALYGRDGEPLARKPRKIEWS
AVAAEKDGHKHFMHKEIFEQPRAVADTIRGRASLEQGDVALDGMELPADYARSLERIVIVACGTSWHAGLSGRQMIESLA
RVPVEVELASEFRNRDPLVDERVLCLAISQSGETADTLAAVKIARARGARAYAICNVVGSAISRECDGGTLFTRAGPEIG
VASTKAFTTQLAALFLMAVRLGRLRGTLSPERARELLEDLRRVPSWMEQMIRQEAQLMPIAKRCAAARDVLFLGRGSEYP
VALEGALKLKEISYIHAEGYAAGEMKHGPIALIDEELPVVVLATREPAYEKTLGNMEEVRARGGQVFAVVTEGDTHAASL
AEVAITVPPAPPVLVPLLSIIPLQFLAYHVADLKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_611_residues
MCGIVGYVGPRQCVDLIVGGLRKLEYRGYDSAGVAVVGPNGLAVKRAKGKLQNLVALLADAPLAGTTGIGHTRWATHGKP
SDENAHPHCYGGVAVVHNGIIENHLELKAALAARGHKFSSETDTEIFAHLIADALAAGARDLRAAVGQALAQVKGTYAIA
VVSQQRPEEIVAAKNASPLVVGYGKGESFLASDVPAILEHTREVVYLEEGELAVLTPAGIALYGRDGEPLARKPRKIEWS
AVAAEKDGHKHFMHKEIFEQPRAVADTIRGRASLEQGDVALDGMELPADYARSLERIVIVACGTSWHAGLSGRQMIESLA
RVPVEVELASEFRNRDPLVDERVLCLAISQSGETADTLAAVKIARARGARAYAICNVVGSAISRECDGGTLFTRAGPEIG
VASTKAFTTQLAALFLMAVRLGRLRGTLSPERARELLEDLRRVPSWMEQMIRQEAQLMPIAKRCAAARDVLFLGRGSEYP
VALEGALKLKEISYIHAEGYAAGEMKHGPIALIDEELPVVVLATREPAYEKTLGNMEEVRARGGQVFAVVTEGDTHAASL
AEVAITVPPAPPVLVPLLSIIPLQFLAYHVADLKGTDVDQPRNLAKSVTVE
>Mature_611_residues
MCGIVGYVGPRQCVDLIVGGLRKLEYRGYDSAGVAVVGPNGLAVKRAKGKLQNLVALLADAPLAGTTGIGHTRWATHGKP
SDENAHPHCYGGVAVVHNGIIENHLELKAALAARGHKFSSETDTEIFAHLIADALAAGARDLRAAVGQALAQVKGTYAIA
VVSQQRPEEIVAAKNASPLVVGYGKGESFLASDVPAILEHTREVVYLEEGELAVLTPAGIALYGRDGEPLARKPRKIEWS
AVAAEKDGHKHFMHKEIFEQPRAVADTIRGRASLEQGDVALDGMELPADYARSLERIVIVACGTSWHAGLSGRQMIESLA
RVPVEVELASEFRNRDPLVDERVLCLAISQSGETADTLAAVKIARARGARAYAICNVVGSAISRECDGGTLFTRAGPEIG
VASTKAFTTQLAALFLMAVRLGRLRGTLSPERARELLEDLRRVPSWMEQMIRQEAQLMPIAKRCAAARDVLFLGRGSEYP
VALEGALKLKEISYIHAEGYAAGEMKHGPIALIDEELPVVVLATREPAYEKTLGNMEEVRARGGQVFAVVTEGDTHAASL
AEVAITVPPAPPVLVPLLSIIPLQFLAYHVADLKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=686, Percent_Identity=37.0262390670554, Blast_Score=441, Evalue=1e-123,
Organism=Homo sapiens, GI205277386, Length=683, Percent_Identity=36.4568081991215, Blast_Score=435, Evalue=1e-122,
Organism=Escherichia coli, GI1790167, Length=614, Percent_Identity=48.5342019543974, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI87082251, Length=314, Percent_Identity=20.3821656050955, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788651, Length=169, Percent_Identity=28.9940828402367, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=718, Percent_Identity=35.6545961002786, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17532899, Length=719, Percent_Identity=34.7705146036161, Blast_Score=384, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17532897, Length=434, Percent_Identity=40.7834101382488, Blast_Score=323, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6322745, Length=436, Percent_Identity=40.3669724770642, Blast_Score=314, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6323731, Length=431, Percent_Identity=31.0904872389791, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6323730, Length=233, Percent_Identity=34.7639484978541, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=37.3177842565598, Blast_Score=448, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65307; Mature: 65307

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYVGPRQCVDLIVGGLRKLEYRGYDSAGVAVVGPNGLAVKRAKGKLQNLVALLAD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHC
APLAGTTGIGHTRWATHGKPSDENAHPHCYGGVAVVHNGIIENHLELKAALAARGHKFSS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCC
ETDTEIFAHLIADALAAGARDLRAAVGQALAQVKGTYAIAVVSQQRPEEIVAAKNASPLV
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCEE
VGYGKGESFLASDVPAILEHTREVVYLEEGELAVLTPAGIALYGRDGEPLARKPRKIEWS
EEECCCCCHHHHCCHHHHHCCCEEEEEECCCEEEEECCCEEEECCCCCHHHCCCCCEEEE
AVAAEKDGHKHFMHKEIFEQPRAVADTIRGRASLEQGDVALDGMELPADYARSLERIVIV
EEECCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHCCCEEEEE
ACGTSWHAGLSGRQMIESLARVPVEVELASEFRNRDPLVDERVLCLAISQSGETADTLAA
EECCCCCCCCCHHHHHHHHHHCCEEEEEHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHH
VKIARARGARAYAICNVVGSAISRECDGGTLFTRAGPEIGVASTKAFTTQLAALFLMAVR
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LGRLRGTLSPERARELLEDLRRVPSWMEQMIRQEAQLMPIAKRCAAARDVLFLGRGSEYP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCC
VALEGALKLKEISYIHAEGYAAGEMKHGPIALIDEELPVVVLATREPAYEKTLGNMEEVR
EEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHCCHHHHH
ARGGQVFAVVTEGDTHAASLAEVAITVPPAPPVLVPLLSIIPLQFLAYHVADLKGTDVDQ
HCCCEEEEEEECCCCCHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PRNLAKSVTVE
HHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYVGPRQCVDLIVGGLRKLEYRGYDSAGVAVVGPNGLAVKRAKGKLQNLVALLAD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHC
APLAGTTGIGHTRWATHGKPSDENAHPHCYGGVAVVHNGIIENHLELKAALAARGHKFSS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCC
ETDTEIFAHLIADALAAGARDLRAAVGQALAQVKGTYAIAVVSQQRPEEIVAAKNASPLV
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCEE
VGYGKGESFLASDVPAILEHTREVVYLEEGELAVLTPAGIALYGRDGEPLARKPRKIEWS
EEECCCCCHHHHCCHHHHHCCCEEEEEECCCEEEEECCCEEEECCCCCHHHCCCCCEEEE
AVAAEKDGHKHFMHKEIFEQPRAVADTIRGRASLEQGDVALDGMELPADYARSLERIVIV
EEECCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHCCCEEEEE
ACGTSWHAGLSGRQMIESLARVPVEVELASEFRNRDPLVDERVLCLAISQSGETADTLAA
EECCCCCCCCCHHHHHHHHHHCCEEEEEHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHH
VKIARARGARAYAICNVVGSAISRECDGGTLFTRAGPEIGVASTKAFTTQLAALFLMAVR
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LGRLRGTLSPERARELLEDLRRVPSWMEQMIRQEAQLMPIAKRCAAARDVLFLGRGSEYP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCC
VALEGALKLKEISYIHAEGYAAGEMKHGPIALIDEELPVVVLATREPAYEKTLGNMEEVR
EEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHCCHHHHH
ARGGQVFAVVTEGDTHAASLAEVAITVPPAPPVLVPLLSIIPLQFLAYHVADLKGTDVDQ
HCCCEEEEEEECCCCCHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PRNLAKSVTVE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA