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The map label for this gene is cusC [C]

Identifier: 220919164

GI number: 220919164

Start: 4564389

End: 4565729

Strand: Direct

Name: cusC [C]

Synonym: A2cp1_4084

Alternate gene names: 220919164

Gene position: 4564389-4565729 (Clockwise)

Preceding gene: 220919163

Following gene: 220919165

Centisome position: 90.76

GC content: 79.94

Gene sequence:

>1341_bases
GTGACCACGCACATTCCTTCCAAGGCCTCCCGCCTGGCGACGCTCGCCGCCGCCGCGGCGCTCCTCGCGCCCGCCGCGGC
CCTCGCCGCGCCGCTCACCATCGAGGACGCGATCCGCGCGGCCTGGGCGCGGAACCCGGGCCTGCAGGCCTCGGCCGCGC
AGGCCGAGGCGGCCCGGGCCGACGCCGACCGCGCCCGCGACGCCCGCCTCCCCACGCTCTCCTTCACCGCCCGGGCGTTC
CGCACCGACGAGCCGATGATGGCGTTCGGCACCCGGCTCGATCAGGGCCGGATCACCATGGCCGACTTCGAGCCCGCCCG
CCTGAACGATCCGCCGGGCATCGGCGGCGTGGGCGCCGGCGCCAGCATCCAGGTGCCGCTGTTCATGGGCGGCCGGCTGC
TCGCCGGGCAGAGCGCCGCGGGCGCCATGGCCGGCGCGGAGGGCGCCTCGCACGCGCAGCGGCAGCGCGAGCTGGCCGCG
GGCGTGGTGCAGGCGTACTTCGGCGCGCAGGCCGCCGACGAGGGCGTCCGCTACGCGGAGGACCTGCTCGCGCAGGCGCA
GGAGACCGAGCGCTTCGTCCGCCAGCGCGCCGCCCAGCAGCTCGCGCTCGAGGCGGACGTGGCCCGCGCGGTGGCGTTCC
GCGCGCAGGCCGAGGCCGAGCGCGCCGCAGCGCTGCAGCGCCGCGCCACCGCCCGCTCGGCGCTCGTGATGCTGGCCGGC
GACGAGGTGGCCGACGCCGAGCTGACCACGCCCATCGACGCGCTGCCCGCGCTCCCCGGAGGCGCCGCCCCGCCGCCCGA
GCGCCCCGACCTGCTCGCCGCGCGCCTGCAGCGCGACGCGGCCGAGGCCGGCGTGCGCGCCGCGCGCGGCAGCCTGCTCC
CGGCGCTGTTCGCCCAGGCGAGCGCCGAGACCCTGCGCACCCCCAGCCTCTCCGACGGCACCGCCTGGACCATGGTGGGC
GTCATGGCGAAGTGGGACCTGTCGCTCGGCGACGCCCGCGCGCTGCGGGCCGCCCAGGCCCGCGCCACCGCCGCCGGCGA
CGCGCTGGTCTGGCGCGAGCGCGAGGCCGCTCGCGAGGGCGGCGAGGCGCGCCGCGCGGTGGAGACCGCCGACGCCCGGG
TGCGCTCCGCCCAGGAGGCGGTGGCCGCCTCCGAGGAGGCGCGCCGGATGCGCGCCGCCCGCCATCGCCAGGGGATGCTC
CCCCTCACCGACCTGCTCGACGCCGAGACCGGCCTCGCCGGCGCCCGGGCCCTGCTCGTCGCGAGCCGCCTGGAGGCGCG
CCTGGCGCGCGCCCGGCTCGCCCTCGCCCTCAACGCTCCCATCGAAGGACTCACGCCATGA

Upstream 100 bases:

>100_bases
CAGCCCCGAGCGTTGGAGCCCGGGTCGGGCGGGAGGATTCGCCCCAGCCTGCCCGGGACGTTGCGGAAACCTTTGGGTGG
CGCGTTGGCTCTGAGCCACC

Downstream 100 bases:

>100_bases
ACCACCGCTCCCTGATGCTCGCGCTCGCGCTCGCCGCCCCGGCGCTCCCCGTCCCCTCCCTCGCCGCCGAGGCCGCGGCC
GCCCCCGCGGCGCCGGCCCG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTTHIPSKASRLATLAAAAALLAPAAALAAPLTIEDAIRAAWARNPGLQASAAQAEAARADADRARDARLPTLSFTARAF
RTDEPMMAFGTRLDQGRITMADFEPARLNDPPGIGGVGAGASIQVPLFMGGRLLAGQSAAGAMAGAEGASHAQRQRELAA
GVVQAYFGAQAADEGVRYAEDLLAQAQETERFVRQRAAQQLALEADVARAVAFRAQAEAERAAALQRRATARSALVMLAG
DEVADAELTTPIDALPALPGGAAPPPERPDLLAARLQRDAAEAGVRAARGSLLPALFAQASAETLRTPSLSDGTAWTMVG
VMAKWDLSLGDARALRAAQARATAAGDALVWREREAAREGGEARRAVETADARVRSAQEAVAASEEARRMRAARHRQGML
PLTDLLDAETGLAGARALLVASRLEARLARARLALALNAPIEGLTP

Sequences:

>Translated_446_residues
MTTHIPSKASRLATLAAAAALLAPAAALAAPLTIEDAIRAAWARNPGLQASAAQAEAARADADRARDARLPTLSFTARAF
RTDEPMMAFGTRLDQGRITMADFEPARLNDPPGIGGVGAGASIQVPLFMGGRLLAGQSAAGAMAGAEGASHAQRQRELAA
GVVQAYFGAQAADEGVRYAEDLLAQAQETERFVRQRAAQQLALEADVARAVAFRAQAEAERAAALQRRATARSALVMLAG
DEVADAELTTPIDALPALPGGAAPPPERPDLLAARLQRDAAEAGVRAARGSLLPALFAQASAETLRTPSLSDGTAWTMVG
VMAKWDLSLGDARALRAAQARATAAGDALVWREREAAREGGEARRAVETADARVRSAQEAVAASEEARRMRAARHRQGML
PLTDLLDAETGLAGARALLVASRLEARLARARLALALNAPIEGLTP
>Mature_445_residues
TTHIPSKASRLATLAAAAALLAPAAALAAPLTIEDAIRAAWARNPGLQASAAQAEAARADADRARDARLPTLSFTARAFR
TDEPMMAFGTRLDQGRITMADFEPARLNDPPGIGGVGAGASIQVPLFMGGRLLAGQSAAGAMAGAEGASHAQRQRELAAG
VVQAYFGAQAADEGVRYAEDLLAQAQETERFVRQRAAQQLALEADVARAVAFRAQAEAERAAALQRRATARSALVMLAGD
EVADAELTTPIDALPALPGGAAPPPERPDLLAARLQRDAAEAGVRAARGSLLPALFAQASAETLRTPSLSDGTAWTMVGV
MAKWDLSLGDARALRAAQARATAAGDALVWREREAAREGGEARRAVETADARVRSAQEAVAASEEARRMRAARHRQGMLP
LTDLLDAETGLAGARALLVASRLEARLARARLALALNAPIEGLTP

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46372; Mature: 46241

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHIPSKASRLATLAAAAALLAPAAALAAPLTIEDAIRAAWARNPGLQASAAQAEAARA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DADRARDARLPTLSFTARAFRTDEPMMAFGTRLDQGRITMADFEPARLNDPPGIGGVGAG
HHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
ASIQVPLFMGGRLLAGQSAAGAMAGAEGASHAQRQRELAAGVVQAYFGAQAADEGVRYAE
CEEEEEEEECCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLLAQAQETERFVRQRAAQQLALEADVARAVAFRAQAEAERAAALQRRATARSALVMLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
DEVADAELTTPIDALPALPGGAAPPPERPDLLAARLQRDAAEAGVRAARGSLLPALFAQA
CCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAETLRTPSLSDGTAWTMVGVMAKWDLSLGDARALRAAQARATAAGDALVWREREAAREG
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GEARRAVETADARVRSAQEAVAASEEARRMRAARHRQGMLPLTDLLDAETGLAGARALLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
ASRLEARLARARLALALNAPIEGLTP
HHHHHHHHHHHHHHHEECCCCCCCCC
>Mature Secondary Structure 
TTHIPSKASRLATLAAAAALLAPAAALAAPLTIEDAIRAAWARNPGLQASAAQAEAARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DADRARDARLPTLSFTARAFRTDEPMMAFGTRLDQGRITMADFEPARLNDPPGIGGVGAG
HHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
ASIQVPLFMGGRLLAGQSAAGAMAGAEGASHAQRQRELAAGVVQAYFGAQAADEGVRYAE
CEEEEEEEECCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLLAQAQETERFVRQRAAQQLALEADVARAVAFRAQAEAERAAALQRRATARSALVMLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
DEVADAELTTPIDALPALPGGAAPPPERPDLLAARLQRDAAEAGVRAARGSLLPALFAQA
CCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAETLRTPSLSDGTAWTMVGVMAKWDLSLGDARALRAAQARATAAGDALVWREREAAREG
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GEARRAVETADARVRSAQEAVAASEEARRMRAARHRQGMLPLTDLLDAETGLAGARALLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
ASRLEARLARARLALALNAPIEGLTP
HHHHHHHHHHHHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA