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The map label for this gene is yexA [H]

Identifier: 220919064

GI number: 220919064

Start: 4435903

End: 4436148

Strand: Direct

Name: yexA [H]

Synonym: A2cp1_3981

Alternate gene names: 220919064

Gene position: 4435903-4436148 (Clockwise)

Preceding gene: 220919055

Following gene: 220919065

Centisome position: 88.2

GC content: 68.29

Gene sequence:

>246_bases
ATGGCGAAGAAGGCGCGCGTGTACGTCACGCTGAAGCGCGGGGTGCTGGACCCGCAGGGGTCGGCGGTGAACCGCGCCCT
GCACGCGATGGGCTACGGCGAGGTCTCGGACGTCCGGCTGGGCAAGTTCATCGAGGTCGCCCTCGACGAGAAGCTCCCCG
AGGCCGAGGCGCGGAAGCGGCTCGAGGAGATGTGCCGCAAGCTGCTCGCCAACACCGTCATCGAGGACTTCCGCATCGAG
CTCTAG

Upstream 100 bases:

>100_bases
CAGCCACAGGATCTGCGCTGCCGAAGCTCCCTCCATGGACCCCGTACCCTAGCAAAACCGGGGTGAGGCGCACGGGGCGG
ATTCTGCTATAAACCCGCGC

Downstream 100 bases:

>100_bases
CTCGGACGGCACCGGACCATGCGCGTCGGCATCCTCACCTTCCCCGGCTCCAACTGCGACCACGACTGCTACCACGTGGT
GAAGCACGTCATGGGCGCCG

Product: phosphoribosylformylglycinamidine synthase PurS

Products: ADP; phosphate; 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MAKKARVYVTLKRGVLDPQGSAVNRALHAMGYGEVSDVRLGKFIEVALDEKLPEAEARKRLEEMCRKLLANTVIEDFRIE
L

Sequences:

>Translated_81_residues
MAKKARVYVTLKRGVLDPQGSAVNRALHAMGYGEVSDVRLGKFIEVALDEKLPEAEARKRLEEMCRKLLANTVIEDFRIE
L
>Mature_80_residues
AKKARVYVTLKRGVLDPQGSAVNRALHAMGYGEVSDVRLGKFIEVALDEKLPEAEARKRLEEMCRKLLANTVIEDFRIEL

Specific function: Unknown

COG id: COG1828

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0062 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003850
- ProDom:   PD010362 [H]

Pfam domain/function: PF02700 PurS [H]

EC number: 6.3.5.3

Molecular weight: Translated: 9158; Mature: 9027

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKARVYVTLKRGVLDPQGSAVNRALHAMGYGEVSDVRLGKFIEVALDEKLPEAEARKR
CCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
LEEMCRKLLANTVIEDFRIEL
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKKARVYVTLKRGVLDPQGSAVNRALHAMGYGEVSDVRLGKFIEVALDEKLPEAEARKR
CCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
LEEMCRKLLANTVIEDFRIEL
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide; L-glutamine; H2O

Specific reaction: ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]