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The map label for this gene is purQ [H]

Identifier: 220919065

GI number: 220919065

Start: 4436167

End: 4436823

Strand: Direct

Name: purQ [H]

Synonym: A2cp1_3982

Alternate gene names: 220919065

Gene position: 4436167-4436823 (Clockwise)

Preceding gene: 220919064

Following gene: 220919066

Centisome position: 88.21

GC content: 71.54

Gene sequence:

>657_bases
ATGCGCGTCGGCATCCTCACCTTCCCCGGCTCCAACTGCGACCACGACTGCTACCACGTGGTGAAGCACGTCATGGGCGC
CGAGGCCCAGTACGTCTGGCACAAGGACCGCCTGCCCGCGAAGCTCGACGCGGTGGTGGTGCCGGGCGGCTTCAGCTACG
GCGACTACCTCCGCTGCGGCGCGCTGGCCCGCTTCTCGCCGGTCATCGCCGACCTCGTCACGTTCGCGCAGCAGGGCGGC
CCGGTGCTCGGCATCTGCAACGGGTTCCAGATCCTGTGCGAGGCCGGGCTGCTGCCCGGCGTCCTGATGCGGAACGCGTC
GCTGAAGTACATCTGCAAGGACGTCACCATCCGCGTCGAGGGGCAGGAGACGCCGGTGACCCGCGGGCTCGCCGGCCAGT
CGCTCACCATGCCGATCGCCCACGCGGAGGGGAACTACTTCGCCGACCCGGAGACGCTCGACCGGCTCGAGGGCGAGGGG
CGCGTCGTGTTCCGCTACGTCGGCGGCGCGCCGAACGGATCGGCCCGCGACATCGCCGGCATCTCCGGCGGCCCGGCGCG
CAACGTGGTCGGCCTCATGCCGCACCCGGACCGCGCCAGCGAGTCGATCCTCGGCCTCGAGGACGGCAAGCGCATGTTCG
CGGCGCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGAGGCGCGGAAGCGGCTCGAGGAGATGTGCCGCAAGCTGCTCGCCAACACCGTCATCGAGGACTTCCGCATCGAGCTCT
AGCTCGGACGGCACCGGACC

Downstream 100 bases:

>100_bases
ACGGGCGGCGTCGCCCGATCCCGGGGGGCCGAGGACGGACGTTGCCACAGGTCGATCTCACCGGGCCGGCGGGCCGGCTG
GAAGCGCTGCTGGAGGAGGT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPAKLDAVVVPGGFSYGDYLRCGALARFSPVIADLVTFAQQGG
PVLGICNGFQILCEAGLLPGVLMRNASLKYICKDVTIRVEGQETPVTRGLAGQSLTMPIAHAEGNYFADPETLDRLEGEG
RVVFRYVGGAPNGSARDIAGISGGPARNVVGLMPHPDRASESILGLEDGKRMFAALLG

Sequences:

>Translated_218_residues
MRVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPAKLDAVVVPGGFSYGDYLRCGALARFSPVIADLVTFAQQGG
PVLGICNGFQILCEAGLLPGVLMRNASLKYICKDVTIRVEGQETPVTRGLAGQSLTMPIAHAEGNYFADPETLDRLEGEG
RVVFRYVGGAPNGSARDIAGISGGPARNVVGLMPHPDRASESILGLEDGKRMFAALLG
>Mature_218_residues
MRVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPAKLDAVVVPGGFSYGDYLRCGALARFSPVIADLVTFAQQGG
PVLGICNGFQILCEAGLLPGVLMRNASLKYICKDVTIRVEGQETPVTRGLAGQSLTMPIAHAEGNYFADPETLDRLEGEG
RVVFRYVGGAPNGSARDIAGISGGPARNVVGLMPHPDRASESILGLEDGKRMFAALLG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=230, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=186, Percent_Identity=30.1075268817204, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582111, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582109, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137292, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23226; Mature: 23226

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPAKLDAVVVPGGFSYGDYLRCG
CEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCHHHHC
ALARFSPVIADLVTFAQQGGPVLGICNGFQILCEAGLLPGVLMRNASLKYICKDVTIRVE
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHCCCCCEEEEEEEEEEEE
GQETPVTRGLAGQSLTMPIAHAEGNYFADPETLDRLEGEGRVVFRYVGGAPNGSARDIAG
CCCCCCCCCCCCCCEEEEEEECCCCEECCHHHHHHHCCCCEEEEEEECCCCCCCCCEECC
ISGGPARNVVGLMPHPDRASESILGLEDGKRMFAALLG
CCCCCCCCEEECCCCCCCCCCCEECCHHHHHHHHHHCC
>Mature Secondary Structure
MRVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPAKLDAVVVPGGFSYGDYLRCG
CEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCHHHHC
ALARFSPVIADLVTFAQQGGPVLGICNGFQILCEAGLLPGVLMRNASLKYICKDVTIRVE
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHCCCCCEEEEEEEEEEEE
GQETPVTRGLAGQSLTMPIAHAEGNYFADPETLDRLEGEGRVVFRYVGGAPNGSARDIAG
CCCCCCCCCCCCCCEEEEEEECCCCEECCHHHHHHHCCCCEEEEEEECCCCCCCCCEECC
ISGGPARNVVGLMPHPDRASESILGLEDGKRMFAALLG
CCCCCCCCEEECCCCCCCCCCCEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA