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The map label for this gene is mcp4 [H]

Identifier: 220918943

GI number: 220918943

Start: 4288439

End: 4290019

Strand: Direct

Name: mcp4 [H]

Synonym: A2cp1_3858

Alternate gene names: 220918943

Gene position: 4288439-4290019 (Clockwise)

Preceding gene: 220918942

Following gene: 220918944

Centisome position: 85.27

GC content: 77.61

Gene sequence:

>1581_bases
ATGCTGCACGCACTCGCCAACCTGTCGATCTCCACCCGCCTTCGCCTGGTGCTGCTCGCCGGCGCCGCCGGCCTGTTCCT
GCTCTCGTGGCAGTCGGTCCGCGTGCTGGAGGCGCGCATGCTCGCCGAGCGCCAGGCCAAGGTCCGCGCGCTCGTGGAGG
CGGCGCACGCGCTCGTCGAGCACCAGGGCGCCCGCGCCACCCGCGGCGAGATCTCCGCCGAGGAGGCCCGCCGCGCGGCG
CTCGAGGCGCTGCGCGCGCTCCGCTACGACGGCGCCGAGTACTTCTGGGTGAACGACCTCGAGCCGCGGATGGTCATGCA
CCCGACCAACCCGCAGCTCGACGGCCAGGACCTGTCCGGCTACCGGGACCCGAACGGCAAGCTGCTGTTCCAGGAGTTCG
TCCGCACGGTGCGCGCGCGCGGCAGCGGCTTCGTGGACTACCTGTGGCCGAAGCCGGGCAGCACGGTGCCGGTGCCGAAG
ATCTCCTTCGTGACGCAGTACCAGCCCTGGGGCTGGGTCGTCGGCTCGGGCCTGTACGTGGACGACCTCGACGCGGCGGT
CCGGAGCGAGGCGCGGCGGGTGCTCGGCACGGGCGCGCTCATCGTGGCGGTGATCCTGGGCGGCGCGGCGCTGGTGGCCC
GCGGCGTCCGCCGCTCGCTGGCGCGCGCGGTGAACGCGGCCGGCGCGGTGGCGTCCGGCGATCTCACCGTGCGGATCCCC
GACGCGGCGCGGGACGAGCCGGGCCGCGTGCTGGACGCGCTCTCCGGCATGGCCGACCGCCTGTCCGCGGTGGTGGGCGA
GGTCCGCGGCGCCTCGGAGTCGATCGCCTCGGCGGCCGAGGAGACGCGCACCGTGGCGGGGACGCTCGCGGAGGCGTCGA
GCGGGCAGGCCTCCGACGTGGCCCGCTCCAGCGAGGCGGTCCGCGAGCTGGTCGCCGAGATCGACGGCGCCGCCTCGGAG
GCGCGGGCCACCGACGCGCTGGCGCGGCGCGCCGCGGACGACGCCGGCGAGGGCGCCCGGGCGGTGCGCGAGACGGCGCT
CGCCATGCGGGCCATCGCCGAGAAGATCGGCGTGGTGGGCGAGATCGCCTACCAGACCAACCTGCTCGCCCTCAACTCGG
CCATCGAGGCGGCCCGCGCCGGCGTGCACGGGCGCGGGTTCGCGGTGGTCGCGACCGAGGTGCGGCGCCTGGCCGAGCGG
AGCCGCGCCGCCGCGCAGGAGATCGGCGAGCTGGCCGGGGGCAGCGTGGCCGCGGCGGATCGCGCCGCCGAGCTGATCGC
GCGCGCGCTGCCCTCCATCGGCGCCACCAGCGAGCGGGTGCAGCGCATCACCGAGGCCGCCGGCCGGCAGCACCAGGCGG
CGCGCGCCATCGGCGACGTGCTCCACGGGCTCGCCGGCGCCTCCGAGCGCCAGGCGGCCGCCTCCGAGGAGCTGGCCGGC
TCGGCCGCCGCGCTCTCCGACAACGCCGAGGAGCTGGCCCGGACGGTGGGCTGGTTCCGCGTGCCCGAAGGAGGGAGCGC
CCTCGCGCCGGTCCCGGCCCGCGTCGAGGCGCCGCGGCGCCCCGGCCGCGAGGCTGCGTGA

Upstream 100 bases:

>100_bases
CATGTGCTTACGCTCCACGCGGATCTGACCCGTGCGGGATGGCGCACCCATCGGCACGAACCTTCCATTGCGCTCGGGCG
GGGAGCCCCTTGGAGGACGG

Downstream 100 bases:

>100_bases
AAGTGCCGCTTGCGGACGGGGCGCGACGGCGTTCCATTTGAGGGCATGCACCTCTTCAGCCCGCTCGCGCTCCGCTCCGT
CACCGTCCGCAACCGCATCG

Product: methyl-accepting chemotaxis sensory transducer with Cache sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MLHALANLSISTRLRLVLLAGAAGLFLLSWQSVRVLEARMLAERQAKVRALVEAAHALVEHQGARATRGEISAEEARRAA
LEALRALRYDGAEYFWVNDLEPRMVMHPTNPQLDGQDLSGYRDPNGKLLFQEFVRTVRARGSGFVDYLWPKPGSTVPVPK
ISFVTQYQPWGWVVGSGLYVDDLDAAVRSEARRVLGTGALIVAVILGGAALVARGVRRSLARAVNAAGAVASGDLTVRIP
DAARDEPGRVLDALSGMADRLSAVVGEVRGASESIASAAEETRTVAGTLAEASSGQASDVARSSEAVRELVAEIDGAASE
ARATDALARRAADDAGEGARAVRETALAMRAIAEKIGVVGEIAYQTNLLALNSAIEAARAGVHGRGFAVVATEVRRLAER
SRAAAQEIGELAGGSVAAADRAAELIARALPSIGATSERVQRITEAAGRQHQAARAIGDVLHGLAGASERQAAASEELAG
SAAALSDNAEELARTVGWFRVPEGGSALAPVPARVEAPRRPGREAA

Sequences:

>Translated_526_residues
MLHALANLSISTRLRLVLLAGAAGLFLLSWQSVRVLEARMLAERQAKVRALVEAAHALVEHQGARATRGEISAEEARRAA
LEALRALRYDGAEYFWVNDLEPRMVMHPTNPQLDGQDLSGYRDPNGKLLFQEFVRTVRARGSGFVDYLWPKPGSTVPVPK
ISFVTQYQPWGWVVGSGLYVDDLDAAVRSEARRVLGTGALIVAVILGGAALVARGVRRSLARAVNAAGAVASGDLTVRIP
DAARDEPGRVLDALSGMADRLSAVVGEVRGASESIASAAEETRTVAGTLAEASSGQASDVARSSEAVRELVAEIDGAASE
ARATDALARRAADDAGEGARAVRETALAMRAIAEKIGVVGEIAYQTNLLALNSAIEAARAGVHGRGFAVVATEVRRLAER
SRAAAQEIGELAGGSVAAADRAAELIARALPSIGATSERVQRITEAAGRQHQAARAIGDVLHGLAGASERQAAASEELAG
SAAALSDNAEELARTVGWFRVPEGGSALAPVPARVEAPRRPGREAA
>Mature_526_residues
MLHALANLSISTRLRLVLLAGAAGLFLLSWQSVRVLEARMLAERQAKVRALVEAAHALVEHQGARATRGEISAEEARRAA
LEALRALRYDGAEYFWVNDLEPRMVMHPTNPQLDGQDLSGYRDPNGKLLFQEFVRTVRARGSGFVDYLWPKPGSTVPVPK
ISFVTQYQPWGWVVGSGLYVDDLDAAVRSEARRVLGTGALIVAVILGGAALVARGVRRSLARAVNAAGAVASGDLTVRIP
DAARDEPGRVLDALSGMADRLSAVVGEVRGASESIASAAEETRTVAGTLAEASSGQASDVARSSEAVRELVAEIDGAASE
ARATDALARRAADDAGEGARAVRETALAMRAIAEKIGVVGEIAYQTNLLALNSAIEAARAGVHGRGFAVVATEVRRLAER
SRAAAQEIGELAGGSVAAADRAAELIARALPSIGATSERVQRITEAAGRQHQAARAIGDVLHGLAGASERQAAASEELAG
SAAALSDNAEELARTVGWFRVPEGGSALAPVPARVEAPRRPGREAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=364, Percent_Identity=29.6703296703297, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI2367378, Length=280, Percent_Identity=34.2857142857143, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788195, Length=328, Percent_Identity=32.9268292682927, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788194, Length=382, Percent_Identity=27.2251308900524, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=32.1888412017167, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54978; Mature: 54978

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHALANLSISTRLRLVLLAGAAGLFLLSWQSVRVLEARMLAERQAKVRALVEAAHALVE
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQGARATRGEISAEEARRAALEALRALRYDGAEYFWVNDLEPRMVMHPTNPQLDGQDLSG
HCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCCCC
YRDPNGKLLFQEFVRTVRARGSGFVDYLWPKPGSTVPVPKISFVTQYQPWGWVVGSGLYV
CCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHEEECCCCCEEEECCCCH
DDLDAAVRSEARRVLGTGALIVAVILGGAALVARGVRRSLARAVNAAGAVASGDLTVRIP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEECC
DAARDEPGRVLDALSGMADRLSAVVGEVRGASESIASAAEETRTVAGTLAEASSGQASDV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ARSSEAVRELVAEIDGAASEARATDALARRAADDAGEGARAVRETALAMRAIAEKIGVVG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHH
EIAYQTNLLALNSAIEAARAGVHGRGFAVVATEVRRLAERSRAAAQEIGELAGGSVAAAD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RAAELIARALPSIGATSERVQRITEAAGRQHQAARAIGDVLHGLAGASERQAAASEELAG
HHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
SAAALSDNAEELARTVGWFRVPEGGSALAPVPARVEAPRRPGREAA
CHHHHCCCHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLHALANLSISTRLRLVLLAGAAGLFLLSWQSVRVLEARMLAERQAKVRALVEAAHALVE
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQGARATRGEISAEEARRAALEALRALRYDGAEYFWVNDLEPRMVMHPTNPQLDGQDLSG
HCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCCCC
YRDPNGKLLFQEFVRTVRARGSGFVDYLWPKPGSTVPVPKISFVTQYQPWGWVVGSGLYV
CCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHEEECCCCCEEEECCCCH
DDLDAAVRSEARRVLGTGALIVAVILGGAALVARGVRRSLARAVNAAGAVASGDLTVRIP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEECC
DAARDEPGRVLDALSGMADRLSAVVGEVRGASESIASAAEETRTVAGTLAEASSGQASDV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ARSSEAVRELVAEIDGAASEARATDALARRAADDAGEGARAVRETALAMRAIAEKIGVVG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHH
EIAYQTNLLALNSAIEAARAGVHGRGFAVVATEVRRLAERSRAAAQEIGELAGGSVAAAD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RAAELIARALPSIGATSERVQRITEAAGRQHQAARAIGDVLHGLAGASERQAAASEELAG
HHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
SAAALSDNAEELARTVGWFRVPEGGSALAPVPARVEAPRRPGREAA
CHHHHCCCHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]