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The map label for this gene is namA [H]

Identifier: 220918944

GI number: 220918944

Start: 4290065

End: 4291123

Strand: Direct

Name: namA [H]

Synonym: A2cp1_3859

Alternate gene names: 220918944

Gene position: 4290065-4291123 (Clockwise)

Preceding gene: 220918943

Following gene: 220918946

Centisome position: 85.3

GC content: 76.39

Gene sequence:

>1059_bases
ATGCACCTCTTCAGCCCGCTCGCGCTCCGCTCCGTCACCGTCCGCAACCGCATCGCCGCCTCCCCGATGTGCCAGTACTC
GGCCAGCGAGGGCCGGGCCAACGACTGGCATCTCGTCCACCTCGGCGCGTTCGCCACCGGCGGCGTCGGGCTGGTGCTGG
TCGAGGCCACCGCCGTCGAGGCCCGCGGCCGCATCTCGCCGCTCGACCTGGGCCTGTGGGAGGACGGGCAGATCGAGCCG
CTCGCGCGCATCGTGCGCTTCGCCGAGGGGCAGGGCGCGGCCATGGGCGTCCAGCTCGCCCACGCCGGGCGCAAGGCCTC
CACCGCCGCGCCCTGGAGCGGCGGCGGGCCGGTGGCGGCCGCGGACGGCGGCTGGCAGCCGGTGGCGCCGAGCGCGCTGC
CGTTCGCGGACGGCTACCCCACCCCCGCGGCGCTCGATCTCGCCGGGATCCGCGGCGTGGTGGACGCGTTCGCGGCCGCC
GCCCGCCGCGCGCGCGCCGCGGGCTTCCGGGTGGCGGAGGTCCACGCGGCGCACGGCTACCTCCTGCACCAGTTCCTCTC
GCCGCTCACCAACCGCCGCACCGACGCGTACGGCGGCGGCTTCGAGAACCGCACCCGCCTGGTGCGCGAGGTCACCGCGG
CGGTGCGCGCCGCCTGGCCGGAAGAGCTCCCCGTGCTGGTCCGCATCTCCGCGACGGACTGGGTGGAGGGCGGCTGGGAC
GCGGAGCAGTCGGTCGAGCTGTGCCGCGCGCTGAAGGCGCTCGGGGTGGACCTGGTGGACGTCTCCACCGGCGGCCTCGT
GCCCGGCGCGAAGATCCCGGTCGGCCCCGGTTACCAGACCGGCTTCGCCGAGCGGATCCGGCGCGAGGCCGGCGTCGCCA
CCGGCTCGGTCGGCATGATCACGTCGCCCGAGCAAGCGGATCACGTGATCCGCTCCGGCCAGGCCGATCTGGTGCTGCTC
GCCCGCGAGCTGCTCCGCGACCCCCACTTCCCGCTCCGCGCGTCGAAGGTGCTGGGCCACGAGGGCCCGTGGCCGAAGCA
GTACCTCCGCGCGCGGTAG

Upstream 100 bases:

>100_bases
GCCGGTCCCGGCCCGCGTCGAGGCGCCGCGGCGCCCCGGCCGCGAGGCTGCGTGAAAGTGCCGCTTGCGGACGGGGCGCG
ACGGCGTTCCATTTGAGGGC

Downstream 100 bases:

>100_bases
CGCCGCGGCGGGCGCCGCCGTGGCTCAGGCGCGCCCGCCCGCCCGCGCGTCCTCCTCGGTGACGTCGGTGGCGCCCTCGG
CCACGTGGCCGGTGCGGCGC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MHLFSPLALRSVTVRNRIAASPMCQYSASEGRANDWHLVHLGAFATGGVGLVLVEATAVEARGRISPLDLGLWEDGQIEP
LARIVRFAEGQGAAMGVQLAHAGRKASTAAPWSGGGPVAAADGGWQPVAPSALPFADGYPTPAALDLAGIRGVVDAFAAA
ARRARAAGFRVAEVHAAHGYLLHQFLSPLTNRRTDAYGGGFENRTRLVREVTAAVRAAWPEELPVLVRISATDWVEGGWD
AEQSVELCRALKALGVDLVDVSTGGLVPGAKIPVGPGYQTGFAERIRREAGVATGSVGMITSPEQADHVIRSGQADLVLL
ARELLRDPHFPLRASKVLGHEGPWPKQYLRAR

Sequences:

>Translated_352_residues
MHLFSPLALRSVTVRNRIAASPMCQYSASEGRANDWHLVHLGAFATGGVGLVLVEATAVEARGRISPLDLGLWEDGQIEP
LARIVRFAEGQGAAMGVQLAHAGRKASTAAPWSGGGPVAAADGGWQPVAPSALPFADGYPTPAALDLAGIRGVVDAFAAA
ARRARAAGFRVAEVHAAHGYLLHQFLSPLTNRRTDAYGGGFENRTRLVREVTAAVRAAWPEELPVLVRISATDWVEGGWD
AEQSVELCRALKALGVDLVDVSTGGLVPGAKIPVGPGYQTGFAERIRREAGVATGSVGMITSPEQADHVIRSGQADLVLL
ARELLRDPHFPLRASKVLGHEGPWPKQYLRAR
>Mature_352_residues
MHLFSPLALRSVTVRNRIAASPMCQYSASEGRANDWHLVHLGAFATGGVGLVLVEATAVEARGRISPLDLGLWEDGQIEP
LARIVRFAEGQGAAMGVQLAHAGRKASTAAPWSGGGPVAAADGGWQPVAPSALPFADGYPTPAALDLAGIRGVVDAFAAA
ARRARAAGFRVAEVHAAHGYLLHQFLSPLTNRRTDAYGGGFENRTRLVREVTAAVRAAWPEELPVLVRISATDWVEGGWD
AEQSVELCRALKALGVDLVDVSTGGLVPGAKIPVGPGYQTGFAERIRREAGVATGSVGMITSPEQADHVIRSGQADLVLL
ARELLRDPHFPLRASKVLGHEGPWPKQYLRAR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=342, Percent_Identity=28.6549707602339, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787939, Length=353, Percent_Identity=30.5949008498584, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17559802, Length=231, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI72001454, Length=255, Percent_Identity=32.5490196078431, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=235, Percent_Identity=33.1914893617021, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=171, Percent_Identity=34.5029239766082, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=226, Percent_Identity=30.0884955752212, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=232, Percent_Identity=31.4655172413793, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=278, Percent_Identity=29.4964028776978, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=27.1111111111111, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=226, Percent_Identity=27.4336283185841, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 37220; Mature: 37220

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLFSPLALRSVTVRNRIAASPMCQYSASEGRANDWHLVHLGAFATGGVGLVLVEATAVE
CCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEHHH
ARGRISPLDLGLWEDGQIEPLARIVRFAEGQGAAMGVQLAHAGRKASTAAPWSGGGPVAA
HCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCCCCCCEEE
ADGGWQPVAPSALPFADGYPTPAALDLAGIRGVVDAFAAAARRARAAGFRVAEVHAAHGY
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
LLHQFLSPLTNRRTDAYGGGFENRTRLVREVTAAVRAAWPEELPVLVRISATDWVEGGWD
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
AEQSVELCRALKALGVDLVDVSTGGLVPGAKIPVGPGYQTGFAERIRREAGVATGSVGMI
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
TSPEQADHVIRSGQADLVLLARELLRDPHFPLRASKVLGHEGPWPKQYLRAR
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MHLFSPLALRSVTVRNRIAASPMCQYSASEGRANDWHLVHLGAFATGGVGLVLVEATAVE
CCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEHHH
ARGRISPLDLGLWEDGQIEPLARIVRFAEGQGAAMGVQLAHAGRKASTAAPWSGGGPVAA
HCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCCCCCCEEE
ADGGWQPVAPSALPFADGYPTPAALDLAGIRGVVDAFAAAARRARAAGFRVAEVHAAHGY
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
LLHQFLSPLTNRRTDAYGGGFENRTRLVREVTAAVRAAWPEELPVLVRISATDWVEGGWD
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
AEQSVELCRALKALGVDLVDVSTGGLVPGAKIPVGPGYQTGFAERIRREAGVATGSVGMI
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
TSPEQADHVIRSGQADLVLLARELLRDPHFPLRASKVLGHEGPWPKQYLRAR
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA