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The map label for this gene is hcaT [H]

Identifier: 220918920

GI number: 220918920

Start: 4259057

End: 4260250

Strand: Direct

Name: hcaT [H]

Synonym: A2cp1_3834

Alternate gene names: 220918920

Gene position: 4259057-4260250 (Clockwise)

Preceding gene: 220918918

Following gene: 220918925

Centisome position: 84.68

GC content: 77.81

Gene sequence:

>1194_bases
ATGGCCTCCGCGGCGCGACTCCGGCTCATGTACTTCCTGTACTACGGGAACGTGGGCGTGGCGCAGCCGTACCTGGCCGC
GTACCTGCGCGGCCTGGGGTTCAGCGGTGAGCAGATCGGCACCGTGCAGATGATCCCCTCGCTGCTCGCGCCGGTGGTGG
CGATGTCGTGGGCGACGTTCGCCGACCGCCACGCCACCCCGGCCCGCGGGCTGCGCCTCGCCACCGCCTGGAGCGCGCTC
TGCGTGCTGGCGCTGCCGTTCGCGCGCACGCCGGCGGCGGTCGGCGCGGTGCTGGTCGCCGCGGCGCTCGGGGACCGCGC
GTACGTGCCGCTGCTCGACTCGGTGACCCTGGAGCACACCCGGGCGCGGCCGGAGCGGTCCTACGCCTCGGTCCGGCTGT
TCGGCTCGATCGGCTTCGTGGTGCTGGCGCTCGTGGTCGGGCGCGCGCTCACGCTGCGCGGCAACCGACCGGCCGACCTG
CTCGTGCCGTCGCTCATGACCGCGCTGGTGGCCGGCTACGCGCTGGCGGCGCGGCGGCTGCCCGCGCACGCCGGGCCGCC
GCACGAGGATCGGCCGGGCCCGCGCGACATGCTCGCGCTGCTCCGCCGGCCGGCGCTGCCGCTCCTGCTGGGCGCGTGCG
CGGTCCACTGGGCCGCCTGCGCGCCGTACCACCTGCTGTTCGGCGTGTACGTGCGCGACCGCGGCCTGCCCGCCGACGTG
ACCGGGCTCGGCACCGCCGCGGGCGTTGCGGCCGAGATCGCCGTGCTGCTCCTGTTCCCCAGGCTGGAGCGGCGCCTGTC
GCTGCGCGGGCTCCTCGCCGCCTCGTTCCTGGGCTCGGCGGTGCGCTGGGCGCTGCTCTGGCGCGCCGAGGGCGCGGCGG
CCATCGTGCTGCTGCAGCTCCTGCACGGCCTCACCTTCGGCCTGTTCTGGGCAGCCGCCATGAAGGGCATGGCCGAGGTG
GTGCCGGCGCGGCTCCGCGCCACCGGCCAGGCGCTGTTCAGCGCGGTGGTGTTCGGGGCCGGCAACGGGGTCGGGTTCGC
GCTCTCCGGCGCCGCCTACGACCGGCTCGGCTCGGTGGCCCCGCTGTTCGCGGGCGCCGCGCTGCTGGAGCTCGCGCTGG
TGGGCGTGGGCCTCGCCGCGGCCGGCGCGCTGGCGGCGGCGCGCGCCCGCGGGGCGGGGCCGGCGGCGCCGTGA

Upstream 100 bases:

>100_bases
GGCTTGGGGACGTGCGCGGTGAGCGGGCGCAGCCGCGTCCCGAGCCCGGCACAGAGGACCATCCCGGCGAGGTCGCCCAT
GGTAGACGCGAGTCTAACCG

Downstream 100 bases:

>100_bases
TCGCGCCCGCGGTCAGGTGAGCTCGCGCAGCCTGCGGGCGCCGAGCGCCTCGCGCAGCACCAGGAACAGCTCGGCGGTGG
CGACCGCGTCGGTGAGCGCG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MASAARLRLMYFLYYGNVGVAQPYLAAYLRGLGFSGEQIGTVQMIPSLLAPVVAMSWATFADRHATPARGLRLATAWSAL
CVLALPFARTPAAVGAVLVAAALGDRAYVPLLDSVTLEHTRARPERSYASVRLFGSIGFVVLALVVGRALTLRGNRPADL
LVPSLMTALVAGYALAARRLPAHAGPPHEDRPGPRDMLALLRRPALPLLLGACAVHWAACAPYHLLFGVYVRDRGLPADV
TGLGTAAGVAAEIAVLLLFPRLERRLSLRGLLAASFLGSAVRWALLWRAEGAAAIVLLQLLHGLTFGLFWAAAMKGMAEV
VPARLRATGQALFSAVVFGAGNGVGFALSGAAYDRLGSVAPLFAGAALLELALVGVGLAAAGALAAARARGAGPAAP

Sequences:

>Translated_397_residues
MASAARLRLMYFLYYGNVGVAQPYLAAYLRGLGFSGEQIGTVQMIPSLLAPVVAMSWATFADRHATPARGLRLATAWSAL
CVLALPFARTPAAVGAVLVAAALGDRAYVPLLDSVTLEHTRARPERSYASVRLFGSIGFVVLALVVGRALTLRGNRPADL
LVPSLMTALVAGYALAARRLPAHAGPPHEDRPGPRDMLALLRRPALPLLLGACAVHWAACAPYHLLFGVYVRDRGLPADV
TGLGTAAGVAAEIAVLLLFPRLERRLSLRGLLAASFLGSAVRWALLWRAEGAAAIVLLQLLHGLTFGLFWAAAMKGMAEV
VPARLRATGQALFSAVVFGAGNGVGFALSGAAYDRLGSVAPLFAGAALLELALVGVGLAAAGALAAARARGAGPAAP
>Mature_396_residues
ASAARLRLMYFLYYGNVGVAQPYLAAYLRGLGFSGEQIGTVQMIPSLLAPVVAMSWATFADRHATPARGLRLATAWSALC
VLALPFARTPAAVGAVLVAAALGDRAYVPLLDSVTLEHTRARPERSYASVRLFGSIGFVVLALVVGRALTLRGNRPADLL
VPSLMTALVAGYALAARRLPAHAGPPHEDRPGPRDMLALLRRPALPLLLGACAVHWAACAPYHLLFGVYVRDRGLPADVT
GLGTAAGVAAEIAVLLLFPRLERRLSLRGLLAASFLGSAVRWALLWRAEGAAAIVLLQLLHGLTFGLFWAAAMKGMAEVV
PARLRATGQALFSAVVFGAGNGVGFALSGAAYDRLGSVAPLFAGAALLELALVGVGLAAAGALAAARARGAGPAAP

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=371, Percent_Identity=27.4932614555256, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 41127; Mature: 40996

Theoretical pI: Translated: 11.28; Mature: 11.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAARLRLMYFLYYGNVGVAQPYLAAYLRGLGFSGEQIGTVQMIPSLLAPVVAMSWATF
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ADRHATPARGLRLATAWSALCVLALPFARTPAAVGAVLVAAALGDRAYVPLLDSVTLEHT
HHCCCCCHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RARPERSYASVRLFGSIGFVVLALVVGRALTLRGNRPADLLVPSLMTALVAGYALAARRL
HCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
PAHAGPPHEDRPGPRDMLALLRRPALPLLLGACAVHWAACAPYHLLFGVYVRDRGLPADV
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGLGTAAGVAAEIAVLLLFPRLERRLSLRGLLAASFLGSAVRWALLWRAEGAAAIVLLQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LHGLTFGLFWAAAMKGMAEVVPARLRATGQALFSAVVFGAGNGVGFALSGAAYDRLGSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHCCHH
PLFAGAALLELALVGVGLAAAGALAAARARGAGPAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASAARLRLMYFLYYGNVGVAQPYLAAYLRGLGFSGEQIGTVQMIPSLLAPVVAMSWATF
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ADRHATPARGLRLATAWSALCVLALPFARTPAAVGAVLVAAALGDRAYVPLLDSVTLEHT
HHCCCCCHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RARPERSYASVRLFGSIGFVVLALVVGRALTLRGNRPADLLVPSLMTALVAGYALAARRL
HCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
PAHAGPPHEDRPGPRDMLALLRRPALPLLLGACAVHWAACAPYHLLFGVYVRDRGLPADV
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGLGTAAGVAAEIAVLLLFPRLERRLSLRGLLAASFLGSAVRWALLWRAEGAAAIVLLQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LHGLTFGLFWAAAMKGMAEVVPARLRATGQALFSAVVFGAGNGVGFALSGAAYDRLGSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHCCHH
PLFAGAALLELALVGVGLAAAGALAAARARGAGPAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]