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The map label for this gene is yfcG [H]

Identifier: 220918619

GI number: 220918619

Start: 3940946

End: 3941551

Strand: Direct

Name: yfcG [H]

Synonym: A2cp1_3527

Alternate gene names: 220918619

Gene position: 3940946-3941551 (Clockwise)

Preceding gene: 220918617

Following gene: 220918621

Centisome position: 78.36

GC content: 76.24

Gene sequence:

>606_bases
ATGAAGCTCTACTACGCGCCGCGCACGCGGGCCACCCGCCCCCGCTGGCTGCTCGAGGAGATGGGCGTTCCCTACGAGCT
GGTCCGGCTCGATCGCGCCGCCGGGGCGCTGCGCACGCCCGAGCACCTCGCCCGCCACCCGATGGGCCGCGTGCCGGTCC
TGGAGGACGGCGACGCCCGCCTCTTCGAGTCGGCCGCCATCTGCCTGTGGCTCGCCGAGCGCTTCCCGGAGAAGGGCATG
CTCCCGCCGGCCGGCACGCCGGGCCGCGCGCTCACCTACCAGTGGCTGTTCTTCGCCATGGACGAGCTGGAGCCGCCGCT
CGAGGCGCTGCACGGGCTGCTCCGTCCGCCCGAGGGCGAGCGCGACGCGGCGGCCATCGAGGCCCAGAAGGCCAGGTTCC
TGGAGGGCGCGCGCGTCCTCGACCTGGCGCTCCGGGGCCGCCCGTTCCTCGCCGGCGACGCGTTCGGCGTGGCCGACCTC
GTCACCGGCGCCGTGGCCTCCTGGGGCAAGGCGCTGGTGGGCGGTATCGACGGGATGCCGGCGCTGGCGGCCTGGCTCGC
CGGCGTGAAGGCGCGGCCCGCCTGGAAGCGGGCCATCGCCGACTGA

Upstream 100 bases:

>100_bases
CGCGGCGGGTGTACCCACCGTGAACGGCCCCCTTCTTCCGGGCCCCGCGGGGCCGCGACCCGGTCTAGAACGATCCGAAC
CCTTCATGGAGGACACCGGG

Downstream 100 bases:

>100_bases
GGCACGGGAGCGCCCCGCGCGGCGCAGCCGCGCCCGCGGGGACCTCGCGCGAGCCCGCGAACGCGGGCGCGCGAGGTCAC
GGGCCCCGCGCAGCCGGGTG

Product: Glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLYYAPRTRATRPRWLLEEMGVPYELVRLDRAAGALRTPEHLARHPMGRVPVLEDGDARLFESAAICLWLAERFPEKGM
LPPAGTPGRALTYQWLFFAMDELEPPLEALHGLLRPPEGERDAAAIEAQKARFLEGARVLDLALRGRPFLAGDAFGVADL
VTGAVASWGKALVGGIDGMPALAAWLAGVKARPAWKRAIAD

Sequences:

>Translated_201_residues
MKLYYAPRTRATRPRWLLEEMGVPYELVRLDRAAGALRTPEHLARHPMGRVPVLEDGDARLFESAAICLWLAERFPEKGM
LPPAGTPGRALTYQWLFFAMDELEPPLEALHGLLRPPEGERDAAAIEAQKARFLEGARVLDLALRGRPFLAGDAFGVADL
VTGAVASWGKALVGGIDGMPALAAWLAGVKARPAWKRAIAD
>Mature_201_residues
MKLYYAPRTRATRPRWLLEEMGVPYELVRLDRAAGALRTPEHLARHPMGRVPVLEDGDARLFESAAICLWLAERFPEKGM
LPPAGTPGRALTYQWLFFAMDELEPPLEALHGLLRPPEGERDAAAIEAQKARFLEGARVLDLALRGRPFLAGDAFGVADL
VTGAVASWGKALVGGIDGMPALAAWLAGVKARPAWKRAIAD

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787923, Length=202, Percent_Identity=27.7227722772277, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI87081789, Length=183, Percent_Identity=32.2404371584699, Blast_Score=61, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922526, Length=191, Percent_Identity=26.7015706806283, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17864594, Length=199, Percent_Identity=27.1356783919598, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 21973; Mature: 21973

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYYAPRTRATRPRWLLEEMGVPYELVRLDRAAGALRTPEHLARHPMGRVPVLEDGDAR
CEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEECCCHH
LFESAAICLWLAERFPEKGMLPPAGTPGRALTYQWLFFAMDELEPPLEALHGLLRPPEGE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
RDAAAIEAQKARFLEGARVLDLALRGRPFLAGDAFGVADLVTGAVASWGKALVGGIDGMP
CHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
ALAAWLAGVKARPAWKRAIAD
HHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MKLYYAPRTRATRPRWLLEEMGVPYELVRLDRAAGALRTPEHLARHPMGRVPVLEDGDAR
CEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEECCCHH
LFESAAICLWLAERFPEKGMLPPAGTPGRALTYQWLFFAMDELEPPLEALHGLLRPPEGE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
RDAAAIEAQKARFLEGARVLDLALRGRPFLAGDAFGVADLVTGAVASWGKALVGGIDGMP
CHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
ALAAWLAGVKARPAWKRAIAD
HHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]