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The map label for this gene is lpxB [H]

Identifier: 220918595

GI number: 220918595

Start: 3917942

End: 3918583

Strand: Reverse

Name: lpxB [H]

Synonym: A2cp1_3503

Alternate gene names: 220918595

Gene position: 3918583-3917942 (Counterclockwise)

Preceding gene: 220918596

Following gene: 220918594

Centisome position: 77.91

GC content: 66.36

Gene sequence:

>642_bases
ATGACCGCGAGCCACCTCTGGATCTTCGCCGTCGGGTTCACCGCCCAGATCCTGTTCGCCGCCAGGATGCTGGTGCAGTG
GTTCCACTCCGAGAAGGCCGGCAAGCCCATCTCCCCGGTGGTCTTCTGGCAGCTCAGCCTGCTCGGCGGGATCCTGTTCT
TCGTCTACGGGATCCTGCGCAAGGACTTCGCCATCGTCCTCGGGCAGCTCATCGTCTACTTCATCTACATCCGGAACCTG
CACCTGCAGCAGCGGTGGATGACCGTGAGCGCGCCGTTCCGGTGGGCCGCCTACCTGGTCCCGGTGCTGAGCGTCGCGTA
CCTCGTCTCCAGCGCGCCCGGCAACCTGCGCGACATCCTCGGCAACGTGGAGATCCCGCTCTGGCTCAAGGTGTGGGGCT
CGGTGGGCCAGGTGGTGTTCACGTTCCGCTTCGTGATGCAGTGGATCGACTCCGAGTCGCGCAAGGAGTCGGTGTTCTCG
AACGGCTTCTGGGTGGTGAGCCTGGTCGGCTCCACGATGATCCTGGTGTATTCCGTGTTCCGCCGCGATCCGGTGCTGTT
CTTCGGGCAGGCCGGCGGCGCGGTGGCCTACTCCCGCAACCTGGTGCTGGGCCTGCGCGCCCGGCGCCACCCCGCCGCAT
GA

Upstream 100 bases:

>100_bases
AGTACCACCTCTGGAACCGGCTGCTCGGCCCCACCGCCGACCTGTTCGCCTACCGCTGGATGCGGAGCCGCTACATCCGC
TACGAGATCGCGAAAAAGGG

Downstream 100 bases:

>100_bases
GCGCCGCGCCCGGTCGCGCCGGCCCGCCCGGCCTGGGCGGGAGGGTCCAGCTCCTGCTGCTCGCCGCGCTCTGCGCCTGC
ACGTTCGTGGTGAACGCGGG

Product: lipid A biosynthesis domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTASHLWIFAVGFTAQILFAARMLVQWFHSEKAGKPISPVVFWQLSLLGGILFFVYGILRKDFAIVLGQLIVYFIYIRNL
HLQQRWMTVSAPFRWAAYLVPVLSVAYLVSSAPGNLRDILGNVEIPLWLKVWGSVGQVVFTFRFVMQWIDSESRKESVFS
NGFWVVSLVGSTMILVYSVFRRDPVLFFGQAGGAVAYSRNLVLGLRARRHPAA

Sequences:

>Translated_213_residues
MTASHLWIFAVGFTAQILFAARMLVQWFHSEKAGKPISPVVFWQLSLLGGILFFVYGILRKDFAIVLGQLIVYFIYIRNL
HLQQRWMTVSAPFRWAAYLVPVLSVAYLVSSAPGNLRDILGNVEIPLWLKVWGSVGQVVFTFRFVMQWIDSESRKESVFS
NGFWVVSLVGSTMILVYSVFRRDPVLFFGQAGGAVAYSRNLVLGLRARRHPAA
>Mature_212_residues
TASHLWIFAVGFTAQILFAARMLVQWFHSEKAGKPISPVVFWQLSLLGGILFFVYGILRKDFAIVLGQLIVYFIYIRNLH
LQQRWMTVSAPFRWAAYLVPVLSVAYLVSSAPGNLRDILGNVEIPLWLKVWGSVGQVVFTFRFVMQWIDSESRKESVFSN
GFWVVSLVGSTMILVYSVFRRDPVLFFGQAGGAVAYSRNLVLGLRARRHPAA

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG3952

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lpxB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835
- InterPro:   IPR011499
- ProDom:   PD339292 [H]

Pfam domain/function: PF07578 LAB_N; PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 24150; Mature: 24019

Theoretical pI: Translated: 11.06; Mature: 11.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASHLWIFAVGFTAQILFAARMLVQWFHSEKAGKPISPVVFWQLSLLGGILFFVYGILR
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KDFAIVLGQLIVYFIYIRNLHLQQRWMTVSAPFRWAAYLVPVLSVAYLVSSAPGNLRDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GNVEIPLWLKVWGSVGQVVFTFRFVMQWIDSESRKESVFSNGFWVVSLVGSTMILVYSVF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RRDPVLFFGQAGGAVAYSRNLVLGLRARRHPAA
HCCCEEEEECCCCEEEECCCEEEEECCCCCCCC
>Mature Secondary Structure 
TASHLWIFAVGFTAQILFAARMLVQWFHSEKAGKPISPVVFWQLSLLGGILFFVYGILR
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KDFAIVLGQLIVYFIYIRNLHLQQRWMTVSAPFRWAAYLVPVLSVAYLVSSAPGNLRDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GNVEIPLWLKVWGSVGQVVFTFRFVMQWIDSESRKESVFSNGFWVVSLVGSTMILVYSVF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RRDPVLFFGQAGGAVAYSRNLVLGLRARRHPAA
HCCCEEEEECCCCEEEECCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]