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The map label for this gene is clpX [H]

Identifier: 220918590

GI number: 220918590

Start: 3912383

End: 3913621

Strand: Reverse

Name: clpX [H]

Synonym: A2cp1_3498

Alternate gene names: 220918590

Gene position: 3913621-3912383 (Counterclockwise)

Preceding gene: 220918591

Following gene: 220918588

Centisome position: 77.82

GC content: 65.94

Gene sequence:

>1239_bases
GTGGAGAAGCGCGAGACGCTGAGCTGCAGCTTCTGCGGCAAGTCGCAGAAGGAAGTGAAGAAGCTCATCGCAGGGCCGAC
GGTCTACATCTGCGACGAGTGCATCGGGCTCTGCAACGACATCATCGCCGAGGAGATCGCCGGCGAGGAGAAGCGTGAGC
AGAAGCTGCGGGTGCCGCGCCCGTCGGAGATCAAGACCATCCTCGACGAGTACGTGGTGGGCCAGGAGCGGGCGAAGAAG
ACGCTCGCGGTCGCGGTCCACAACCACTACAAGCGCATCGAGAGCCGCGTCTCGATCGACGACGTCGAGCTGCAGAAGTC
GAACATCCTGCTGCTCGGCCCCACCGGCTCCGGCAAGACGCTGCTCGCGCAGACGCTCGCCAAGATCCTCAACGTCCCGT
TCACGATCGCCGACGCCACCACGCTCACCGAGGCGGGCTACGTCGGCGAGGACGTCGAGAACATCATCGTCAACCTGCTG
CAGGCCGCCGACCACGACATCGAGCGGGCGCAGAAGGGCATCGTCTACATCGACGAGATCGACAAGATCGCCCGCAAGAG
CGAGAACCCGTCGATCACCCGCGACGTGTCCGGCGAGGGCGTGCAGCAGGCGCTGCTCAAGATCATCGAGGGCACCGTCG
CGAACGTCCCGCCGAAGGGCGGCCGCAAGCATCCCCAGCAGGAGTTCCTGCAGGTCGACACGACCAACATCCTGTTCATC
TGCGGCGGCGCGTTCTGCGGGCTGGAGCAGATCATCGAGCGGCGCTCCGGCGGGCGCAGCCTCGGCTTCGGCACCGACGT
GAAGTCGAAGACCGAGAAGAACGTGGGCGAGCTGCTCGCGATGGTGGAGCCGGACGACCTGCTCAAGTTCGGGATGATCC
CCGAGTTCGTGGGCCGCCTGCCGGTCATCACCAGCCTGGAGGAGCTCGATCAGCCGGCGCTGGTGGACATCCTCACGCGG
CCGCGCAACGCGCTGGTGAAGCAGTACAAGAAGCTGCTCGAGATGGACGGGGTGAACCTCAAGTTCACCGACGGCGCGCT
GGTCGCCATCGCCCGCGCCGCCATGAAGAACAAGGCCGGCGCCCGCGGCCTGCGCGCCATCCTCGAGAACGCGATGCTCG
ACATCATGTACGACGTGCCGAGCCGCCGGAACGTCCGGGAGATCGTCATCTCCGAGGACGTGGTCGACAAGCACGAGGCG
CCGCTGGTGGTGATGCAGAAGGAGGCGGAGTCGGCGTAG

Upstream 100 bases:

>100_bases
CAAGAAGCCACAGTAAGATGAGGGAAGAGGCGAGGCGCCGGAGGGCATCCTCACCAGGGGAAGCAGCCGAGGAAGCGGGC
TCGCGAACCGGAGGTGGCAC

Downstream 100 bases:

>100_bases
GTCCCTCGACTCCGCGCCGCTCGCGCGGCGCTACGCTCGGGATGAGCGCGTCGATCCGGATGTAGGCCCGCTCACCCTGA
GCGTAGGCGGCCCTAGGCCG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MEKRETLSCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIAGEEKREQKLRVPRPSEIKTILDEYVVGQERAKK
TLAVAVHNHYKRIESRVSIDDVELQKSNILLLGPTGSGKTLLAQTLAKILNVPFTIADATTLTEAGYVGEDVENIIVNLL
QAADHDIERAQKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKIIEGTVANVPPKGGRKHPQQEFLQVDTTNILFI
CGGAFCGLEQIIERRSGGRSLGFGTDVKSKTEKNVGELLAMVEPDDLLKFGMIPEFVGRLPVITSLEELDQPALVDILTR
PRNALVKQYKKLLEMDGVNLKFTDGALVAIARAAMKNKAGARGLRAILENAMLDIMYDVPSRRNVREIVISEDVVDKHEA
PLVVMQKEAESA

Sequences:

>Translated_412_residues
MEKRETLSCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIAGEEKREQKLRVPRPSEIKTILDEYVVGQERAKK
TLAVAVHNHYKRIESRVSIDDVELQKSNILLLGPTGSGKTLLAQTLAKILNVPFTIADATTLTEAGYVGEDVENIIVNLL
QAADHDIERAQKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKIIEGTVANVPPKGGRKHPQQEFLQVDTTNILFI
CGGAFCGLEQIIERRSGGRSLGFGTDVKSKTEKNVGELLAMVEPDDLLKFGMIPEFVGRLPVITSLEELDQPALVDILTR
PRNALVKQYKKLLEMDGVNLKFTDGALVAIARAAMKNKAGARGLRAILENAMLDIMYDVPSRRNVREIVISEDVVDKHEA
PLVVMQKEAESA
>Mature_412_residues
MEKRETLSCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIAGEEKREQKLRVPRPSEIKTILDEYVVGQERAKK
TLAVAVHNHYKRIESRVSIDDVELQKSNILLLGPTGSGKTLLAQTLAKILNVPFTIADATTLTEAGYVGEDVENIIVNLL
QAADHDIERAQKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKIIEGTVANVPPKGGRKHPQQEFLQVDTTNILFI
CGGAFCGLEQIIERRSGGRSLGFGTDVKSKTEKNVGELLAMVEPDDLLKFGMIPEFVGRLPVITSLEELDQPALVDILTR
PRNALVKQYKKLLEMDGVNLKFTDGALVAIARAAMKNKAGARGLRAILENAMLDIMYDVPSRRNVREIVISEDVVDKHEA
PLVVMQKEAESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=339, Percent_Identity=51.3274336283186, Blast_Score=317, Evalue=1e-86,
Organism=Escherichia coli, GI1786642, Length=409, Percent_Identity=65.5256723716381, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1790366, Length=238, Percent_Identity=35.7142857142857, Blast_Score=104, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71982908, Length=292, Percent_Identity=48.972602739726, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=307, Percent_Identity=46.9055374592834, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=425, Percent_Identity=38.5882352941176, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=40.7692307692308, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=40, Blast_Score=269, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=50.6289308176101, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=50.6289308176101, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45337; Mature: 45337

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00250 TGF_BETA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRETLSCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIAGEEKREQKLRVPR
CCCCCCCEEHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
PSEIKTILDEYVVGQERAKKTLAVAVHNHYKRIESRVSIDDVELQKSNILLLGPTGSGKT
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCHH
LLAQTLAKILNVPFTIADATTLTEAGYVGEDVENIIVNLLQAADHDIERAQKGIVYIDEI
HHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCEEEHHH
DKIARKSENPSITRDVSGEGVQQALLKIIEGTVANVPPKGGRKHPQQEFLQVDTTNILFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHCCCCEEEE
CGGAFCGLEQIIERRSGGRSLGFGTDVKSKTEKNVGELLAMVEPDDLLKFGMIPEFVGRL
ECCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHCCC
PVITSLEELDQPALVDILTRPRNALVKQYKKLLEMDGVNLKFTDGALVAIARAAMKNKAG
CHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCC
ARGLRAILENAMLDIMYDVPSRRNVREIVISEDVVDKHEAPLVVMQKEAESA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MEKRETLSCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIAGEEKREQKLRVPR
CCCCCCCEEHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
PSEIKTILDEYVVGQERAKKTLAVAVHNHYKRIESRVSIDDVELQKSNILLLGPTGSGKT
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCHH
LLAQTLAKILNVPFTIADATTLTEAGYVGEDVENIIVNLLQAADHDIERAQKGIVYIDEI
HHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCEEEHHH
DKIARKSENPSITRDVSGEGVQQALLKIIEGTVANVPPKGGRKHPQQEFLQVDTTNILFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHCCCCEEEE
CGGAFCGLEQIIERRSGGRSLGFGTDVKSKTEKNVGELLAMVEPDDLLKFGMIPEFVGRL
ECCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHCCC
PVITSLEELDQPALVDILTRPRNALVKQYKKLLEMDGVNLKFTDGALVAIARAAMKNKAG
CHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCC
ARGLRAILENAMLDIMYDVPSRRNVREIVISEDVVDKHEAPLVVMQKEAESA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA