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The map label for this gene is yicO [C]

Identifier: 220918582

GI number: 220918582

Start: 3902405

End: 3903775

Strand: Direct

Name: yicO [C]

Synonym: A2cp1_3490

Alternate gene names: 220918582

Gene position: 3902405-3903775 (Clockwise)

Preceding gene: 220918581

Following gene: 220918585

Centisome position: 77.59

GC content: 71.55

Gene sequence:

>1371_bases
GTGACCGCTCCCGCCTCCGCCCTCGATCGCTTCTTCGGCCTCCGCGCCCGCGGCACCACCGTGCGGCGCGAGATCCTGGC
CGGCACCACCACCTTCATGACGATGGCGTACATCCTGTTCGTGAACCCGGAGATCCTCGGGAACGCGGCGGGCGCGGGCC
ACTTCGCGGCCATCCTCACCTCGACGGCGCTGGTGGCCGCGGTCATGACCGCGGCCATGGGGCTGTTCGCGAACCTGCCG
CTCGCGCTCGCCTCGGGCATGGGGCTGAACGCGGTGGTGGCGTTCGGGCTGGTGCTGGGCAAGAAGCTCACCTACCCGCA
GGCCATGGGCGTCATCGTGGCGGAGGGCCTGCTCATCACGCTGCTGGTCGCCACCGGCCTGCGCCAGGCGGTGGTGCGCG
CGGTGCCGATGACGCTGAAGCGCGCCATCGGCATCGGCATCGGCCTGTTCCTCGCCATCATCGGCTTCAAGGGCGCCGGC
TTCATCTCGGCGGGCGGCGCGCTGCTGCAGCTCGGGCCCGAGGGCGCCGCGGGCCGCCTGGCCGGGTTCCCGGTGGTGCT
GTTCGCGCTCACGCTCGTGTTCACCGCCTGGCTCGTGTCGCGCGGCGTGCGCGGCGCCCTGCTCATCGGCATCGCGGTCT
CCACCGCGGTGGCGGTGGCCGCGAAGGCGGCGTTCGGCGGCGCGGGCTTCGCCCCGCACGTCGCGAACCTGCCCAGCTCG
ATCTTCGGCCTGCCCGACTTCTCCATGCTCGGCCAGGTGGACTTCTCGTTCGTGACGGTCCTCGGCTGGCTCGCGGCCTC
CCTGGCGGTCTTCTCGATCATGCTCTCCGACTTCTTCGACACGGTCGGCACCGTGGTCGCGGTGGGCCAGGAGGCGAAGT
ACCTGGACGAGAACGGCAACTTCCCCCGCGCCAGCACGGTGCTGATGGTGGACTCCCTCGCCGCGATCGCGGGCGGGCTC
GCCGGCGCCAGCTCGGCGACGACCTACGTGGAGAGCGCCGCGGGCGCGGCCTCCGGCGGCCGCACCGGGCTCACCTCGGT
GACCACGGCAGCGCTGTTCGCGCTGTGCCTCTTCATCTCGCCGCTCGCCGGCATCGTCCCGCCGCAGGCCACCGGGGCGG
TGCTGGTGCTGGTCGGCTACATGATGATGCGCGACGTCGGCTCCATCGCCTGGGACGATCCCACCGAGTCGATCCCCGCG
TTCCTGACGGTGACCGTGATGCCGTTCACCTACTCCATCACGAACGGCATCGGCGCCGGGTTCGTCTCCTACGTGCTCCT
GAAGCTCGCCGGCGGCAAGGCGCGCCAGGTCCACCCGCTCATGATCGGGGCCTCGATCGCGTTCGTGGTCTACTTCGCCA
TCGGCGGGTAG

Upstream 100 bases:

>100_bases
CCGCGGGCCCGGGTGCCGTCGAGGCGCCCGGGCCCGTCCATTTTGCCGCGCCGCCCCGCCCAGGGCCCCTGATATCCTCC
GCCGCCTCAAGGAGATCGCC

Downstream 100 bases:

>100_bases
GCGGCGGGCCGGCGGCCGGGCCCCGGAGGGCGCCGCGCCGGCCCTGGCCGGCTCACGCGTCCCGCGGCACCGCGATCATC
CGCTCCAGCGCGCGGCGCGC

Product: Xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTAPASALDRFFGLRARGTTVRREILAGTTTFMTMAYILFVNPEILGNAAGAGHFAAILTSTALVAAVMTAAMGLFANLP
LALASGMGLNAVVAFGLVLGKKLTYPQAMGVIVAEGLLITLLVATGLRQAVVRAVPMTLKRAIGIGIGLFLAIIGFKGAG
FISAGGALLQLGPEGAAGRLAGFPVVLFALTLVFTAWLVSRGVRGALLIGIAVSTAVAVAAKAAFGGAGFAPHVANLPSS
IFGLPDFSMLGQVDFSFVTVLGWLAASLAVFSIMLSDFFDTVGTVVAVGQEAKYLDENGNFPRASTVLMVDSLAAIAGGL
AGASSATTYVESAAGAASGGRTGLTSVTTAALFALCLFISPLAGIVPPQATGAVLVLVGYMMMRDVGSIAWDDPTESIPA
FLTVTVMPFTYSITNGIGAGFVSYVLLKLAGGKARQVHPLMIGASIAFVVYFAIGG

Sequences:

>Translated_456_residues
MTAPASALDRFFGLRARGTTVRREILAGTTTFMTMAYILFVNPEILGNAAGAGHFAAILTSTALVAAVMTAAMGLFANLP
LALASGMGLNAVVAFGLVLGKKLTYPQAMGVIVAEGLLITLLVATGLRQAVVRAVPMTLKRAIGIGIGLFLAIIGFKGAG
FISAGGALLQLGPEGAAGRLAGFPVVLFALTLVFTAWLVSRGVRGALLIGIAVSTAVAVAAKAAFGGAGFAPHVANLPSS
IFGLPDFSMLGQVDFSFVTVLGWLAASLAVFSIMLSDFFDTVGTVVAVGQEAKYLDENGNFPRASTVLMVDSLAAIAGGL
AGASSATTYVESAAGAASGGRTGLTSVTTAALFALCLFISPLAGIVPPQATGAVLVLVGYMMMRDVGSIAWDDPTESIPA
FLTVTVMPFTYSITNGIGAGFVSYVLLKLAGGKARQVHPLMIGASIAFVVYFAIGG
>Mature_455_residues
TAPASALDRFFGLRARGTTVRREILAGTTTFMTMAYILFVNPEILGNAAGAGHFAAILTSTALVAAVMTAAMGLFANLPL
ALASGMGLNAVVAFGLVLGKKLTYPQAMGVIVAEGLLITLLVATGLRQAVVRAVPMTLKRAIGIGIGLFLAIIGFKGAGF
ISAGGALLQLGPEGAAGRLAGFPVVLFALTLVFTAWLVSRGVRGALLIGIAVSTAVAVAAKAAFGGAGFAPHVANLPSSI
FGLPDFSMLGQVDFSFVTVLGWLAASLAVFSIMLSDFFDTVGTVVAVGQEAKYLDENGNFPRASTVLMVDSLAAIAGGLA
GASSATTYVESAAGAASGGRTGLTSVTTAALFALCLFISPLAGIVPPQATGAVLVLVGYMMMRDVGSIAWDDPTESIPAF
LTVTVMPFTYSITNGIGAGFVSYVLLKLAGGKARQVHPLMIGASIAFVVYFAIGG

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=442, Percent_Identity=40.4977375565611, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1790150, Length=452, Percent_Identity=40.2654867256637, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1790499, Length=468, Percent_Identity=34.6153846153846, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI48994909, Length=461, Percent_Identity=34.70715835141, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46186; Mature: 46055

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPASALDRFFGLRARGTTVRREILAGTTTFMTMAYILFVNPEILGNAAGAGHFAAILT
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHH
STALVAAVMTAAMGLFANLPLALASGMGLNAVVAFGLVLGKKLTYPQAMGVIVAEGLLIT
HHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLVATGLRQAVVRAVPMTLKRAIGIGIGLFLAIIGFKGAGFISAGGALLQLGPEGAAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCCCCCC
AGFPVVLFALTLVFTAWLVSRGVRGALLIGIAVSTAVAVAAKAAFGGAGFAPHVANLPSS
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHH
IFGLPDFSMLGQVDFSFVTVLGWLAASLAVFSIMLSDFFDTVGTVVAVGQEAKYLDENGN
HCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
FPRASTVLMVDSLAAIAGGLAGASSATTYVESAAGAASGGRTGLTSVTTAALFALCLFIS
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
PLAGIVPPQATGAVLVLVGYMMMRDVGSIAWDDPTESIPAFLTVTVMPFTYSITNGIGAG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHEEEHHCCCHHH
FVSYVLLKLAGGKARQVHPLMIGASIAFVVYFAIGG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAPASALDRFFGLRARGTTVRREILAGTTTFMTMAYILFVNPEILGNAAGAGHFAAILT
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHH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HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]