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The map label for this gene is ffh [H]

Identifier: 220918542

GI number: 220918542

Start: 3840141

End: 3841793

Strand: Direct

Name: ffh [H]

Synonym: A2cp1_3450

Alternate gene names: 220918542

Gene position: 3840141-3841793 (Clockwise)

Preceding gene: 220918540

Following gene: 220918543

Centisome position: 76.35

GC content: 69.75

Gene sequence:

>1653_bases
GTGCTCGAGACCGTATCCAAGGGCTTCAAGGCTGCCCGCAACAAGCTGAAGGGGCGCACCGAGATCACCCCGGAGGTCGT
GGACGACGCGCTCCGCGACATCCGCGTGTCCCTGCTCGAGGCCGACGTCTCGTTCGACGTGGTGAAGCGGTTCGTCGCCC
GCGTCCGCGAGAAGGCCATCGGCGAGGTGGTCGAGACGAAGGTGAAGACGGAGAAGGGGCAGCTCCGCGTCACGCCCCAG
GACCACTTCGTCAAGATCTGCCACGACGAGCTCGAGGCGCTGATGGGCCCGGTGGACACGTCGCTCCGCCAGGGCGAGCG
CGGCCGCCCCACCGGCATCATGATGGTCGGCCTGCAGGGCTCCGGCAAGACGACGACGGCCGGCAAGATCGCGAACCGCC
TCCTCAAGGACGGCAAGCAGGTCATGCTGGTGGCGGCGGACGTGTACCGCCCCGCCGCCGTGGACCAGCTCAAGGTGCTG
GGCGAGCGGCTCGGCGTGCCGGTGTTCCACGAGCCGGGCGTCTCGCCGCCGGACATGTGCCGCCACGCGTTCGAGGCGGC
GCAGCGCGACCACCGCAACGCGGTCATCTACGACACCGCCGGCCGGCTCGCCATCGACGACGAGCTCATGACCGAGCTCG
AGAACATCAAGGCGAACGTCGCGCCCGAGAACATCCTGCTCGTCGCCGACGCCATGATCGGCCAGGACGCGGTCAAGACC
GCGACCGAGTTCGACCGGCGCCTCGCCATCGACGGCTTCATCCTGACGAAGCTCGACGGCGACGCCCGCGGCGGCGCGGC
GCTCTCGATCAAGGAGGTCACCGGCAAGCCCATCAAGTTCCTCGGCATGGGCGAGGCGCTGGATCGCCTCGAGGAGTTCC
GGCCCGAGGGGCTCGCCTCCCGCATCCTGGGCTTCGGCGACATCGTCGGCCTGGTGAAGGACTTCGAGCAGCACGTCGAC
GAGGAGACCGCAGAGGCCGAGGCGCAGAAGATCCTCTCCGGCGACTTCACGCTCGAGGACTTCGTCAACCAGATCCGGAT
GGTCCGGAAGATGGGCCCGCTCGGCGAGCTCATGGAGAAGTTCCCGATGTTCGGGGAGCTTCCCGAGAACTTCCAGTTCG
ACGACTCCGCCCTCACGCGCATCGTGGCGATGGTCGACTCGATGACGCAGGCCGAGCGGCTCCGCCCGGACTCGATCACC
GACCAGCGCGTGAAGCGGATCGCGAAGGGCGCCGGCCGGACCGAGAAGGACGTCCGCGACCTGCTCAAGCAGTACAACGC
CATGCGCGGCGTGATGAAGCAGGTGGGGTCCGCGCCCGGCCTGCTGGCGCGGCTGCCCGGCGTGAAGCAGCTCATGCAGC
TCCGCAAGATGCAGGGCAAGGGCATGGAGGACGTGCTCGGCGCCGACGCCGACGCGGTCGAGCGCGCCATGCAGGGCGGC
CTCGTGGACCCGCGCATGGCCGCGCAGATGGCCGGGCTGCCCAAGGGCTACACGCCGCCCATGTCGGCCGGCGCCATGGC
GCGCGCCCGGATGATGGGCTACGCGCCCGAGCCGATCGCGCTCGAGAGCGCCAAGGAGCGCGAGGCCCGCAAGAAGAAGC
GCAAGGCCGAGCGCCAGGCGCGCAAGAAGGGCCGGAAGAAGGGCCGCCGCTGA

Upstream 100 bases:

>100_bases
GGTGAAGTACCGGGGGCCCTCGTCCATGGGCGGAAACCTCGTCATCTCCGTGTTATAAGCGCGGCGCGTGGCCCGACCAG
GGCCGAAAGGATCACGCCGA

Downstream 100 bases:

>100_bases
TCCGGAGCGCGTGGTGGACCTGCCCCGCCAGCGCGCGCTCTCGACGTACCGCGCGGCGCCGTTCCGCCCGCCCGCCTGCG
CCGGCGCGGTCTACCCCGAC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MLETVSKGFKAARNKLKGRTEITPEVVDDALRDIRVSLLEADVSFDVVKRFVARVREKAIGEVVETKVKTEKGQLRVTPQ
DHFVKICHDELEALMGPVDTSLRQGERGRPTGIMMVGLQGSGKTTTAGKIANRLLKDGKQVMLVAADVYRPAAVDQLKVL
GERLGVPVFHEPGVSPPDMCRHAFEAAQRDHRNAVIYDTAGRLAIDDELMTELENIKANVAPENILLVADAMIGQDAVKT
ATEFDRRLAIDGFILTKLDGDARGGAALSIKEVTGKPIKFLGMGEALDRLEEFRPEGLASRILGFGDIVGLVKDFEQHVD
EETAEAEAQKILSGDFTLEDFVNQIRMVRKMGPLGELMEKFPMFGELPENFQFDDSALTRIVAMVDSMTQAERLRPDSIT
DQRVKRIAKGAGRTEKDVRDLLKQYNAMRGVMKQVGSAPGLLARLPGVKQLMQLRKMQGKGMEDVLGADADAVERAMQGG
LVDPRMAAQMAGLPKGYTPPMSAGAMARARMMGYAPEPIALESAKEREARKKKRKAERQARKKGRKKGRR

Sequences:

>Translated_550_residues
MLETVSKGFKAARNKLKGRTEITPEVVDDALRDIRVSLLEADVSFDVVKRFVARVREKAIGEVVETKVKTEKGQLRVTPQ
DHFVKICHDELEALMGPVDTSLRQGERGRPTGIMMVGLQGSGKTTTAGKIANRLLKDGKQVMLVAADVYRPAAVDQLKVL
GERLGVPVFHEPGVSPPDMCRHAFEAAQRDHRNAVIYDTAGRLAIDDELMTELENIKANVAPENILLVADAMIGQDAVKT
ATEFDRRLAIDGFILTKLDGDARGGAALSIKEVTGKPIKFLGMGEALDRLEEFRPEGLASRILGFGDIVGLVKDFEQHVD
EETAEAEAQKILSGDFTLEDFVNQIRMVRKMGPLGELMEKFPMFGELPENFQFDDSALTRIVAMVDSMTQAERLRPDSIT
DQRVKRIAKGAGRTEKDVRDLLKQYNAMRGVMKQVGSAPGLLARLPGVKQLMQLRKMQGKGMEDVLGADADAVERAMQGG
LVDPRMAAQMAGLPKGYTPPMSAGAMARARMMGYAPEPIALESAKEREARKKKRKAERQARKKGRKKGRR
>Mature_550_residues
MLETVSKGFKAARNKLKGRTEITPEVVDDALRDIRVSLLEADVSFDVVKRFVARVREKAIGEVVETKVKTEKGQLRVTPQ
DHFVKICHDELEALMGPVDTSLRQGERGRPTGIMMVGLQGSGKTTTAGKIANRLLKDGKQVMLVAADVYRPAAVDQLKVL
GERLGVPVFHEPGVSPPDMCRHAFEAAQRDHRNAVIYDTAGRLAIDDELMTELENIKANVAPENILLVADAMIGQDAVKT
ATEFDRRLAIDGFILTKLDGDARGGAALSIKEVTGKPIKFLGMGEALDRLEEFRPEGLASRILGFGDIVGLVKDFEQHVD
EETAEAEAQKILSGDFTLEDFVNQIRMVRKMGPLGELMEKFPMFGELPENFQFDDSALTRIVAMVDSMTQAERLRPDSIT
DQRVKRIAKGAGRTEKDVRDLLKQYNAMRGVMKQVGSAPGLLARLPGVKQLMQLRKMQGKGMEDVLGADADAVERAMQGG
LVDPRMAAQMAGLPKGYTPPMSAGAMARARMMGYAPEPIALESAKEREARKKKRKAERQARKKGRKKGRR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=454, Percent_Identity=31.9383259911894, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI226371618, Length=369, Percent_Identity=34.1463414634146, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI23308697, Length=317, Percent_Identity=28.0757097791798, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI295424842, Length=317, Percent_Identity=28.0757097791798, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI89061728, Length=137, Percent_Identity=37.2262773722628, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1788963, Length=434, Percent_Identity=43.5483870967742, Blast_Score=344, Evalue=1e-95,
Organism=Escherichia coli, GI1789874, Length=217, Percent_Identity=40.0921658986175, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=453, Percent_Identity=32.6710816777042, Blast_Score=212, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI193206261, Length=326, Percent_Identity=27.3006134969325, Blast_Score=106, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=461, Percent_Identity=31.236442516269, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320498, Length=221, Percent_Identity=28.9592760180996, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17647949, Length=502, Percent_Identity=29.8804780876494, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24641198, Length=230, Percent_Identity=31.304347826087, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 60569; Mature: 60569

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETVSKGFKAARNKLKGRTEITPEVVDDALRDIRVSLLEADVSFDVVKRFVARVREKAI
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GEVVETKVKTEKGQLRVTPQDHFVKICHDELEALMGPVDTSLRQGERGRPTGIMMVGLQG
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEEECC
SGKTTTAGKIANRLLKDGKQVMLVAADVYRPAAVDQLKVLGERLGVPVFHEPGVSPPDMC
CCCCCHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
RHAFEAAQRDHRNAVIYDTAGRLAIDDELMTELENIKANVAPENILLVADAMIGQDAVKT
HHHHHHHHHHCCCEEEEECCCCEEECHHHHHHHHHHHCCCCCCCEEEEEHHHHCHHHHHH
ATEFDRRLAIDGFILTKLDGDARGGAALSIKEVTGKPIKFLGMGEALDRLEEFRPEGLAS
HHHHHHHHHHCCEEEEEECCCCCCCCEEEEHHHCCCCEEEEECHHHHHHHHHHCCCHHHH
RILGFGDIVGLVKDFEQHVDEETAEAEAQKILSGDFTLEDFVNQIRMVRKMGPLGELMEK
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHH
FPMFGELPENFQFDDSALTRIVAMVDSMTQAERLRPDSITDQRVKRIAKGAGRTEKDVRD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHH
LLKQYNAMRGVMKQVGSAPGLLARLPGVKQLMQLRKMQGKGMEDVLGADADAVERAMQGG
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCC
LVDPRMAAQMAGLPKGYTPPMSAGAMARARMMGYAPEPIALESAKEREARKKKRKAERQA
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHH
RKKGRKKGRR
HHHHHHCCCC
>Mature Secondary Structure
MLETVSKGFKAARNKLKGRTEITPEVVDDALRDIRVSLLEADVSFDVVKRFVARVREKAI
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GEVVETKVKTEKGQLRVTPQDHFVKICHDELEALMGPVDTSLRQGERGRPTGIMMVGLQG
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEEECC
SGKTTTAGKIANRLLKDGKQVMLVAADVYRPAAVDQLKVLGERLGVPVFHEPGVSPPDMC
CCCCCHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
RHAFEAAQRDHRNAVIYDTAGRLAIDDELMTELENIKANVAPENILLVADAMIGQDAVKT
HHHHHHHHHHCCCEEEEECCCCEEECHHHHHHHHHHHCCCCCCCEEEEEHHHHCHHHHHH
ATEFDRRLAIDGFILTKLDGDARGGAALSIKEVTGKPIKFLGMGEALDRLEEFRPEGLAS
HHHHHHHHHHCCEEEEEECCCCCCCCEEEEHHHCCCCEEEEECHHHHHHHHHHCCCHHHH
RILGFGDIVGLVKDFEQHVDEETAEAEAQKILSGDFTLEDFVNQIRMVRKMGPLGELMEK
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHH
FPMFGELPENFQFDDSALTRIVAMVDSMTQAERLRPDSITDQRVKRIAKGAGRTEKDVRD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHH
LLKQYNAMRGVMKQVGSAPGLLARLPGVKQLMQLRKMQGKGMEDVLGADADAVERAMQGG
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCC
LVDPRMAAQMAGLPKGYTPPMSAGAMARARMMGYAPEPIALESAKEREARKKKRKAERQA
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHH
RKKGRKKGRR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335643; 9384377; 7511896 [H]