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The map label for this gene is hipO [H]

Identifier: 220918460

GI number: 220918460

Start: 3743524

End: 3744786

Strand: Direct

Name: hipO [H]

Synonym: A2cp1_3364

Alternate gene names: 220918460

Gene position: 3743524-3744786 (Clockwise)

Preceding gene: 220918459

Following gene: 220918464

Centisome position: 74.43

GC content: 73.48

Gene sequence:

>1263_bases
ATGGCGAACGCGCAAGATCCCGGCGGACTCCTCGCCACGCTCGACGCATTGCTCCCGGACCTGGAGAGCCTCTACACCGA
CCTCCACGCGCACCCCGAGCTCTCGATGCAGGAGACCCGCACCGCGGCGATCGCGGCGGACCGGCTTCGCGCCGCCGGCT
ACGAGGTGACCACCGGCATCGGGAAGACCGGCGTCGTCGGCCTGCTTCGCAACCGCGATGGTCCCACGGTGATGCTCCGC
GCCGACATGGACGCGCTGCCGGTGAAGGAGCTGACCGGGCTCCCGTACGCGAGCACCGTCACGGCGACCGACGCGGAGGG
CAGGAACGTCCCGGTGATGCACGCCTGCGGCCACGACATGCACGTGGCGTGGCTCGCCGGAGCGGCGACGTTGTTCGGGC
GCGCCCGCACCGCGTGGCGGGGGACGCTGCTCACGGTGTTCCAGCCGGCCGAGGAGATCGCCACCGGCGCGCAGGCGATG
ATCGACGACGGGCTGTTCACGCGCTTTCCCAGGCCCGACGTGGTGCTCGGTCAGCACGTCATGGTCGGCGCGGCGGGCGT
GCTGGGCTGGCGCGCCGGCGTCATGACCTCCGCGGGCGACAGCCTGCAGATCCGGCTGTTCGGGCGCGGGGCGCACGGCT
CGATGCCCCAGGCCAGCATCGACCCGGTGGTGATGGCGGCCGCCACCGTGCTCCGCCTCCAGACGATCGTCTCCCGCGAG
CTGGCCGCGAGCGAGGCGGCCGTCGTCACCGTGGGCGCCCTGCAGGCCGGCACCAAGGAGAACGTCATCCCCGACGAGGC
GCTCATCAAGCTGAACGTGCGCACGTTCGACGAGGGCGTGCGAACGCGCGTGCTCGCCGCCATCGAGCGGATCGTGAAGG
CCGAGGCGGCCGCGTCGGGGGCGCCCAGGCCGCCCGAGATCACGCCGCTCGATCGCTACGGCGCCGTCGTGAACGACGCC
GAGGCGACCCGTCGCGTCGTCGAGGCGTTCCACCGGAGCTTCCCGGCGGAGCGCGTGCAGGAGGTGGCGCCGACGTCCGC
GAGCGAGGACTTCGGCTGCTTCGGCGCCCAGTGGCACGTGCCCGCCGTGTTCTGGTTCGTGGGCGGGACCGATCCGGAGT
CCTACCGCAACGCCCGGGCGGCGGGCCGGCTGGGAGAGCTCCCCACCAACCACAACCCGCGCTTCGCGCCGGTGCTGCAC
CCGACGCTGCGCACCGGCGTCGAGGCCGCGGTGTCGGCCGCGATGGGCTGGCTCGCGCCGTGA

Upstream 100 bases:

>100_bases
GCCGGAGAGGGGACCTCTCCCGAGCCGGCCCGCCCTGCCCGACGTCCGCTAGCATCGCGTGCACCCTCGAGACCCGGCTC
ACGGGTGGAGCGAGAACCCG

Downstream 100 bases:

>100_bases
CCGCCCCGGGCCAGTCCGGCCCGTGACGCGGCGGGCGGCCAGCGGGTGCACGTGAGCCGATCGGTCTCGGCGCCGCGGCC
ATCCACCGCGGAACGGCCTC

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MANAQDPGGLLATLDALLPDLESLYTDLHAHPELSMQETRTAAIAADRLRAAGYEVTTGIGKTGVVGLLRNRDGPTVMLR
ADMDALPVKELTGLPYASTVTATDAEGRNVPVMHACGHDMHVAWLAGAATLFGRARTAWRGTLLTVFQPAEEIATGAQAM
IDDGLFTRFPRPDVVLGQHVMVGAAGVLGWRAGVMTSAGDSLQIRLFGRGAHGSMPQASIDPVVMAAATVLRLQTIVSRE
LAASEAAVVTVGALQAGTKENVIPDEALIKLNVRTFDEGVRTRVLAAIERIVKAEAAASGAPRPPEITPLDRYGAVVNDA
EATRRVVEAFHRSFPAERVQEVAPTSASEDFGCFGAQWHVPAVFWFVGGTDPESYRNARAAGRLGELPTNHNPRFAPVLH
PTLRTGVEAAVSAAMGWLAP

Sequences:

>Translated_420_residues
MANAQDPGGLLATLDALLPDLESLYTDLHAHPELSMQETRTAAIAADRLRAAGYEVTTGIGKTGVVGLLRNRDGPTVMLR
ADMDALPVKELTGLPYASTVTATDAEGRNVPVMHACGHDMHVAWLAGAATLFGRARTAWRGTLLTVFQPAEEIATGAQAM
IDDGLFTRFPRPDVVLGQHVMVGAAGVLGWRAGVMTSAGDSLQIRLFGRGAHGSMPQASIDPVVMAAATVLRLQTIVSRE
LAASEAAVVTVGALQAGTKENVIPDEALIKLNVRTFDEGVRTRVLAAIERIVKAEAAASGAPRPPEITPLDRYGAVVNDA
EATRRVVEAFHRSFPAERVQEVAPTSASEDFGCFGAQWHVPAVFWFVGGTDPESYRNARAAGRLGELPTNHNPRFAPVLH
PTLRTGVEAAVSAAMGWLAP
>Mature_419_residues
ANAQDPGGLLATLDALLPDLESLYTDLHAHPELSMQETRTAAIAADRLRAAGYEVTTGIGKTGVVGLLRNRDGPTVMLRA
DMDALPVKELTGLPYASTVTATDAEGRNVPVMHACGHDMHVAWLAGAATLFGRARTAWRGTLLTVFQPAEEIATGAQAMI
DDGLFTRFPRPDVVLGQHVMVGAAGVLGWRAGVMTSAGDSLQIRLFGRGAHGSMPQASIDPVVMAAATVLRLQTIVSREL
AASEAAVVTVGALQAGTKENVIPDEALIKLNVRTFDEGVRTRVLAAIERIVKAEAAASGAPRPPEITPLDRYGAVVNDAE
ATRRVVEAFHRSFPAERVQEVAPTSASEDFGCFGAQWHVPAVFWFVGGTDPESYRNARAAGRLGELPTNHNPRFAPVLHP
TLRTGVEAAVSAAMGWLAP

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=332, Percent_Identity=28.0120481927711, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 44436; Mature: 44305

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAQDPGGLLATLDALLPDLESLYTDLHAHPELSMQETRTAAIAADRLRAAGYEVTTGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEECCC
GKTGVVGLLRNRDGPTVMLRADMDALPVKELTGLPYASTVTATDAEGRNVPVMHACGHDM
CCCCCEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCCEEEECCCCCCCCCEEEECCCCC
HVAWLAGAATLFGRARTAWRGTLLTVFQPAEEIATGAQAMIDDGLFTRFPRPDVVLGQHV
CHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCHHHHHCCCHHCCCCCCCCEECCHH
MVGAAGVLGWRAGVMTSAGDSLQIRLFGRGAHGSMPQASIDPVVMAAATVLRLQTIVSRE
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LAASEAAVVTVGALQAGTKENVIPDEALIKLNVRTFDEGVRTRVLAAIERIVKAEAAASG
HHCCCCEEEEEEHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
APRPPEITPLDRYGAVVNDAEATRRVVEAFHRSFPAERVQEVAPTSASEDFGCFGAQWHV
CCCCCCCCCHHHHCCHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCC
PAVFWFVGGTDPESYRNARAAGRLGELPTNHNPRFAPVLHPTLRTGVEAAVSAAMGWLAP
CEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANAQDPGGLLATLDALLPDLESLYTDLHAHPELSMQETRTAAIAADRLRAAGYEVTTGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEECCC
GKTGVVGLLRNRDGPTVMLRADMDALPVKELTGLPYASTVTATDAEGRNVPVMHACGHDM
CCCCCEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCCEEEECCCCCCCCCEEEECCCCC
HVAWLAGAATLFGRARTAWRGTLLTVFQPAEEIATGAQAMIDDGLFTRFPRPDVVLGQHV
CHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCHHHHHCCCHHCCCCCCCCEECCHH
MVGAAGVLGWRAGVMTSAGDSLQIRLFGRGAHGSMPQASIDPVVMAAATVLRLQTIVSRE
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LAASEAAVVTVGALQAGTKENVIPDEALIKLNVRTFDEGVRTRVLAAIERIVKAEAAASG
HHCCCCEEEEEEHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
APRPPEITPLDRYGAVVNDAEATRRVVEAFHRSFPAERVQEVAPTSASEDFGCFGAQWHV
CCCCCCCCCHHHHCCHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCC
PAVFWFVGGTDPESYRNARAAGRLGELPTNHNPRFAPVLHPTLRTGVEAAVSAAMGWLAP
CEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]