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The map label for this gene is acoC [H]

Identifier: 220918464

GI number: 220918464

Start: 3747951

End: 3748931

Strand: Direct

Name: acoC [H]

Synonym: A2cp1_3368

Alternate gene names: 220918464

Gene position: 3747951-3748931 (Clockwise)

Preceding gene: 220918460

Following gene: 220918465

Centisome position: 74.52

GC content: 74.72

Gene sequence:

>981_bases
ATGACCCCCCACCACGACGCCCTCGCCGCGCGCCCTCGCACGCCTCGCACGCCCCGATCGCCCACGCGACCTCGTCCGCG
CGCCTTCGCCACGCTCGCCAGCGTGCTCTGCGCCTGCGCGGCCGCCGGCACCCAGCACACCTCCAGCCTCGAGAGACCCG
CCATGAACGCCCCCGAACGCCCCCGCTCCTCCGGATACGCGGACGTCGACGGCCTGCGCCTCTACTACGAGATCCGCGGC
ACCGGCGGGGCGCCGCTGGTCCTCCTGCACGGCGGCCTGCACAACAGCGCGCTCGACGCCCCCGTCGCCGAGCGCCTCGC
CGCGCACCGCCAGGTGATCTCGGTGGACCTGCAGGCCCACGGCCGCACCGCCGACGTCGAGCGACCGCTCCGCTTCGAGC
GGCTCGCCGACGACGTCGCCGCGCTGCTCGCCCAGCTCCGGATCCCGCGGGCCGATCTTCTCGGCTACTCGCTCGGCGGC
GGGGTTGCCCTGAGGACGGCGATCCAGCACCCCGAGCGCGTCCGCAGGCTGGTCCTCGTGTCGGTGCCGTTCTCCGACGC
GGGGTGGTACCCCGAGGTGAAGGCGGGGTTCCAGCACCTCGGCCGCGCGCTCGCAGAGCCGATGCGGCCGTCGCCCGTGT
ACCAGACGTACGCCGCCATCGCGCCGCACCCCGAGCGCTTTCCCGACCTGCTCGACAAGCTGGGGGAGCTCGAGAACCGC
CCATACGACTGGTCGGCGGACGTCGCGCAGGTGACCGCGCCCACCCTGCTCGTCTACGCCGACGCGGACGCCATCCGGCC
CGAGCACGCGGTCCAGCTCTTCCAGCGGCTCGGCGGCGGGCGCCGCGACGGCGGCCTCGATCGCAGCGGCGTGTCGAAGG
CGCGGCTCGCGATCCTCCCCGGGCTCACCCACTACGAGGTGTTCGAGTCGCCCGCGATGCCCGTCGCGGTCGAGCCGTTC
CTGGATGCGCCGGAAGGGTGA

Upstream 100 bases:

>100_bases
CATGGCCGCGCCACCACGCGCGCCGGGCGGTGAACCGGGGTCGACCTCCCGCTTGGGTCGCGCGCGATGAGATCCGACGG
GCTACGACGTCGAGGGCCAC

Downstream 100 bases:

>100_bases
CGCGACGTCCCGGCGGGCGGGCGCCACGGCGACTCGCGCACGCTCGCGGCCGGTTTGCCGGCCGCGAGCGGCTTGCGCAG
CTTGTCGATGACCCCTGGAG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTPHHDALAARPRTPRTPRSPTRPRPRAFATLASVLCACAAAGTQHTSSLERPAMNAPERPRSSGYADVDGLRLYYEIRG
TGGAPLVLLHGGLHNSALDAPVAERLAAHRQVISVDLQAHGRTADVERPLRFERLADDVAALLAQLRIPRADLLGYSLGG
GVALRTAIQHPERVRRLVLVSVPFSDAGWYPEVKAGFQHLGRALAEPMRPSPVYQTYAAIAPHPERFPDLLDKLGELENR
PYDWSADVAQVTAPTLLVYADADAIRPEHAVQLFQRLGGGRRDGGLDRSGVSKARLAILPGLTHYEVFESPAMPVAVEPF
LDAPEG

Sequences:

>Translated_326_residues
MTPHHDALAARPRTPRTPRSPTRPRPRAFATLASVLCACAAAGTQHTSSLERPAMNAPERPRSSGYADVDGLRLYYEIRG
TGGAPLVLLHGGLHNSALDAPVAERLAAHRQVISVDLQAHGRTADVERPLRFERLADDVAALLAQLRIPRADLLGYSLGG
GVALRTAIQHPERVRRLVLVSVPFSDAGWYPEVKAGFQHLGRALAEPMRPSPVYQTYAAIAPHPERFPDLLDKLGELENR
PYDWSADVAQVTAPTLLVYADADAIRPEHAVQLFQRLGGGRRDGGLDRSGVSKARLAILPGLTHYEVFESPAMPVAVEPF
LDAPEG
>Mature_325_residues
TPHHDALAARPRTPRTPRSPTRPRPRAFATLASVLCACAAAGTQHTSSLERPAMNAPERPRSSGYADVDGLRLYYEIRGT
GGAPLVLLHGGLHNSALDAPVAERLAAHRQVISVDLQAHGRTADVERPLRFERLADDVAALLAQLRIPRADLLGYSLGGG
VALRTAIQHPERVRRLVLVSVPFSDAGWYPEVKAGFQHLGRALAEPMRPSPVYQTYAAIAPHPERFPDLLDKLGELENRP
YDWSADVAQVTAPTLLVYADADAIRPEHAVQLFQRLGGGRRDGGLDRSGVSKARLAILPGLTHYEVFESPAMPVAVEPFL
DAPEG

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789817, Length=228, Percent_Identity=32.8947368421053, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 35349; Mature: 35217

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHHDALAARPRTPRTPRSPTRPRPRAFATLASVLCACAAAGTQHTSSLERPAMNAPER
CCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
PRSSGYADVDGLRLYYEIRGTGGAPLVLLHGGLHNSALDAPVAERLAAHRQVISVDLQAH
CCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEHHCC
GRTADVERPLRFERLADDVAALLAQLRIPRADLLGYSLGGGVALRTAIQHPERVRRLVLV
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCHHHHHEEEEE
SVPFSDAGWYPEVKAGFQHLGRALAEPMRPSPVYQTYAAIAPHPERFPDLLDKLGELENR
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PYDWSADVAQVTAPTLLVYADADAIRPEHAVQLFQRLGGGRRDGGLDRSGVSKARLAILP
CCCCCCCHHHHCCCEEEEEECCHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCC
GLTHYEVFESPAMPVAVEPFLDAPEG
CCHHHHHHCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
TPHHDALAARPRTPRTPRSPTRPRPRAFATLASVLCACAAAGTQHTSSLERPAMNAPER
CCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
PRSSGYADVDGLRLYYEIRGTGGAPLVLLHGGLHNSALDAPVAERLAAHRQVISVDLQAH
CCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEHHCC
GRTADVERPLRFERLADDVAALLAQLRIPRADLLGYSLGGGVALRTAIQHPERVRRLVLV
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCHHHHHEEEEE
SVPFSDAGWYPEVKAGFQHLGRALAEPMRPSPVYQTYAAIAPHPERFPDLLDKLGELENR
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PYDWSADVAQVTAPTLLVYADADAIRPEHAVQLFQRLGGGRRDGGLDRSGVSKARLAILP
CCCCCCCHHHHCCCEEEEEECCHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCC
GLTHYEVFESPAMPVAVEPFLDAPEG
CCHHHHHHCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]