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The map label for this gene is ompR [H]

Identifier: 220918235

GI number: 220918235

Start: 3469346

End: 3470062

Strand: Reverse

Name: ompR [H]

Synonym: A2cp1_3138

Alternate gene names: 220918235

Gene position: 3470062-3469346 (Counterclockwise)

Preceding gene: 220918237

Following gene: 220918234

Centisome position: 69.0

GC content: 75.17

Gene sequence:

>717_bases
ATGACCGGGCTCGATCCCGAACGCTTCCGCGTCCTGTTCGTCGAGGACGACGAGCGGCTCGCGGCGCTGACCACCCGCTA
CCTCGAGTCGCACGGGCACGCCGTGACCTGGGTGGCCGACGGGCAGCTCGGGCTGGCCGAGGCGCTGAAGGGCCAGCACG
ACGTGGTCATCCTCGATCTGATGCTGCCGCGGAAGTCCGGGCTGGAGGTGTGCCGCGAGCTCCGCGCGCGGCTGCCGGTG
CCGATCATCATGCTCACCGCGCTCGGCGAGGAGGCCGACCGCGTGCTCGGCCTGGAGACCGGCGCGGACGACTACCTCGC
GAAGCCGTTCTCGTCGCGCGAGCTGCTGGCCCGCCTGCGCGCGCTGGTCCGGCGCGGCCGCGGGTCGCTCGGGCCGCCGC
GGGAGGTGATCCGCGTGGGCGATCTCGAGCTCTCGCCCCGCGACTGGTCGGCGTCGCGCGCCGGGCGGCCGCTGCGGCTC
ACCACCGCCGAGTTCGTGCTGCTGCGCGTCCTGGCGGAGCGCGCCGGCCGCGTGCTCACCCGCGAGCAGCTCCTCGACCT
CACCAAGGGCAGCGCCGACGAGGCGTTCGACCGCTCCATCGACGCCCACATCTCGCGCCTGCGCCACAAGCTCGGCGACG
ACCCTCGCCGGCCCGCGCTCCTCAAGACGGTCCGCGGCGCCGGGTACGTGCTCGCCGCCGGGCCGGAGGGCGCGTGA

Upstream 100 bases:

>100_bases
CGTTGGCGCGCGCGTGACCGCATCGTGACGAAACGTTCGCGCCGCGGCGGTGCCGCGCTCCGCCCGCGACCGCCGGCCCG
CGAGGTGGCAAGATCCGGGC

Downstream 100 bases:

>100_bases
GCGGCGGCGCCGGGGGCGGCGGCCCGTCCCGGCTCGGGCTGCGCATCTACCTCGTCACGGTCGTGGCGGTGCTCGCGACC
GGCGTCGCGGTGCTCCTCGC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTGLDPERFRVLFVEDDERLAALTTRYLESHGHAVTWVADGQLGLAEALKGQHDVVILDLMLPRKSGLEVCRELRARLPV
PIIMLTALGEEADRVLGLETGADDYLAKPFSSRELLARLRALVRRGRGSLGPPREVIRVGDLELSPRDWSASRAGRPLRL
TTAEFVLLRVLAERAGRVLTREQLLDLTKGSADEAFDRSIDAHISRLRHKLGDDPRRPALLKTVRGAGYVLAAGPEGA

Sequences:

>Translated_238_residues
MTGLDPERFRVLFVEDDERLAALTTRYLESHGHAVTWVADGQLGLAEALKGQHDVVILDLMLPRKSGLEVCRELRARLPV
PIIMLTALGEEADRVLGLETGADDYLAKPFSSRELLARLRALVRRGRGSLGPPREVIRVGDLELSPRDWSASRAGRPLRL
TTAEFVLLRVLAERAGRVLTREQLLDLTKGSADEAFDRSIDAHISRLRHKLGDDPRRPALLKTVRGAGYVLAAGPEGA
>Mature_237_residues
TGLDPERFRVLFVEDDERLAALTTRYLESHGHAVTWVADGQLGLAEALKGQHDVVILDLMLPRKSGLEVCRELRARLPVP
IIMLTALGEEADRVLGLETGADDYLAKPFSSRELLARLRALVRRGRGSLGPPREVIRVGDLELSPRDWSASRAGRPLRLT
TAEFVLLRVLAERAGRVLTREQLLDLTKGSADEAFDRSIDAHISRLRHKLGDDPRRPALLKTVRGAGYVLAAGPEGA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=43.0379746835443, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=43.8053097345133, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=39.7379912663755, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=42.6724137931034, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=39.3162393162393, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=37.3333333333333, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=38.1578947368421, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=35.4978354978355, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=37.7777777777778, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=38.1818181818182, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=36.2445414847162, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.7826086956522, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=32.5991189427313, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=32.3275862068966, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26247; Mature: 26115

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLDPERFRVLFVEDDERLAALTTRYLESHGHAVTWVADGQLGLAEALKGQHDVVILDL
CCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCEEEEEE
MLPRKSGLEVCRELRARLPVPIIMLTALGEEADRVLGLETGADDYLAKPFSSRELLARLR
ECCCCHHHHHHHHHHHHCCCCEEHEEHHCCHHHHEEECCCCCCHHHHCCCCHHHHHHHHH
ALVRRGRGSLGPPREVIRVGDLELSPRDWSASRAGRPLRLTTAEFVLLRVLAERAGRVLT
HHHHHCCCCCCCHHHHHEECCCEECCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHCCHHH
REQLLDLTKGSADEAFDRSIDAHISRLRHKLGDDPRRPALLKTVRGAGYVLAAGPEGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure 
TGLDPERFRVLFVEDDERLAALTTRYLESHGHAVTWVADGQLGLAEALKGQHDVVILDL
CCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCEEEEEE
MLPRKSGLEVCRELRARLPVPIIMLTALGEEADRVLGLETGADDYLAKPFSSRELLARLR
ECCCCHHHHHHHHHHHHCCCCEEHEEHHCCHHHHEEECCCCCCHHHHCCCCHHHHHHHHH
ALVRRGRGSLGPPREVIRVGDLELSPRDWSASRAGRPLRLTTAEFVLLRVLAERAGRVLT
HHHHHCCCCCCCHHHHHEECCCEECCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHCCHHH
REQLLDLTKGSADEAFDRSIDAHISRLRHKLGDDPRRPALLKTVRGAGYVLAAGPEGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]