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The map label for this gene is rstB [H]

Identifier: 220918234

GI number: 220918234

Start: 3467940

End: 3469349

Strand: Reverse

Name: rstB [H]

Synonym: A2cp1_3137

Alternate gene names: 220918234

Gene position: 3469349-3467940 (Counterclockwise)

Preceding gene: 220918235

Following gene: 220918233

Centisome position: 68.98

GC content: 79.79

Gene sequence:

>1410_bases
GTGAGCGGCGGCGCCGGGGGCGGCGGCCCGTCCCGGCTCGGGCTGCGCATCTACCTCGTCACGGTCGTGGCGGTGCTCGC
GACCGGCGTCGCGGTGCTCCTCGCGCTCGCGCTCGCGCGGGACCGCCGCGAGCCGGTCCGGCGGGACGTCATGCACGCGG
TCGCCCGCGACGCCGCGGCGCGGGTGGCGACGCAGTGGGGCTCGGCCGGCGCCATCCAGGAGGTGATCGGGCCGCTCGCC
TCGGCGCTGCGCGTGAGCGTCGCCGTGTACGGCGCCGGAGGCGAGCCGGTGGCGAGCGCCGGCGAGGCGATGCGCCCGCC
GCTCCCACCGCCGCCGGAGCGCGAGCGGTTCACGGACCGCCTCGGGCCCGGGCCGCCCGGCGCGGGAGGACGGGAGCGGC
ACGTGGTGTCGGCGGTCGCGCCCGTGGTCGTCGCCGGCGCGCCGGTGGGGTTCCTCGTCGTCGCGCAGCAGGTCCCGGGC
GGTCGCCCGCCGCCCGTCCTGCTCGTCCTCGTCGCGCTGGCGCTGGTCGGCGCGGGCGTCGCGGCGGTGGTGCTGGGCGG
CTCGCTCGCGCGGCCGCTCGACCGGCTGGCGCGCACCGCCCGCGCGCTCGGCGCGGGCGACCTCGCGGCGCGGACCGGGA
TCTCGCGGGCGGACGAGCTCGGGGCCGTCGCGCGCGCGTTCGACGAGATGGCCGACCGCGTCGGCGCGCTGCTCCGCTCC
AGCACCGAGCTGATGGCCAACGTGGCCCACGAGCTGCGCACCCCGCTCGCCCGCATCCGCGTGGCGCTCGACCTCGCCGC
CGAAGGCGACGCCGACGTCGCGCGCGCGTCGCTCGCGGACATCGCGGAGGACCTGTCCGAGCTGGAGCGCCTGGTGGACG
ACGTGCTCGCCTCGGCGCGGCTCGACCTGGCGGGGAACGGCGCCTCCTCCGCGGGCGGGGCGCCACCGCTCCGCCGGGCG
CGGCTGGACCCCGCGGGCGTGGTGCGGCAGGCGGTGGAGCGCCTCGGGCACCGCCACCCGGATCGCGCCGTCCGGCTCGA
GCTCGGGCCCGACCTGCCCGAAGTCGAGGCGGACGCGGTGCTGCTGCGCCGCGCGCTGGACAACCTGCTCGACAACGCGC
GCAAGTACTCGGCGCCGGCCTCGCCGATCCGCGTGGAGGCGGCGCGCCGCGGCGCGGACCTGGTGGTCGAGGTGAGCGAT
CGCGGTGAGGGGATCGCCGCCGAGGAGCTGGAGCGCGTGTTCTCGCCGTTCTACCGGGTGGACCGCAGCCGCGCGCGCGC
CACCGGCGGCGTCGGCCTCGGGCTCCCGCTCGCGCGCCGCATCGCCGAGGCGCACGGCGGCACGCTCACGGCGCGCAGCA
CGCCGGGGGAGGGCACCACCCTCACGCTGACCATCCCGGGCGTTCGCTGA

Upstream 100 bases:

>100_bases
CGCGCCTGCGCCACAAGCTCGGCGACGACCCTCGCCGGCCCGCGCTCCTCAAGACGGTCCGCGGCGCCGGGTACGTGCTC
GCCGCCGGGCCGGAGGGCGC

Downstream 100 bases:

>100_bases
CGGCGGGCCGCGTCGGCACCACCGGGGCGGACGGGCGGGCATCCGGCCGCGCCGCTCCGGCCCGGCGCGGGCGCGGCACG
GGAAAGCCTCCACCGTCGCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSGGAGGGGPSRLGLRIYLVTVVAVLATGVAVLLALALARDRREPVRRDVMHAVARDAAARVATQWGSAGAIQEVIGPLA
SALRVSVAVYGAGGEPVASAGEAMRPPLPPPPERERFTDRLGPGPPGAGGRERHVVSAVAPVVVAGAPVGFLVVAQQVPG
GRPPPVLLVLVALALVGAGVAAVVLGGSLARPLDRLARTARALGAGDLAARTGISRADELGAVARAFDEMADRVGALLRS
STELMANVAHELRTPLARIRVALDLAAEGDADVARASLADIAEDLSELERLVDDVLASARLDLAGNGASSAGGAPPLRRA
RLDPAGVVRQAVERLGHRHPDRAVRLELGPDLPEVEADAVLLRRALDNLLDNARKYSAPASPIRVEAARRGADLVVEVSD
RGEGIAAEELERVFSPFYRVDRSRARATGGVGLGLPLARRIAEAHGGTLTARSTPGEGTTLTLTIPGVR

Sequences:

>Translated_469_residues
MSGGAGGGGPSRLGLRIYLVTVVAVLATGVAVLLALALARDRREPVRRDVMHAVARDAAARVATQWGSAGAIQEVIGPLA
SALRVSVAVYGAGGEPVASAGEAMRPPLPPPPERERFTDRLGPGPPGAGGRERHVVSAVAPVVVAGAPVGFLVVAQQVPG
GRPPPVLLVLVALALVGAGVAAVVLGGSLARPLDRLARTARALGAGDLAARTGISRADELGAVARAFDEMADRVGALLRS
STELMANVAHELRTPLARIRVALDLAAEGDADVARASLADIAEDLSELERLVDDVLASARLDLAGNGASSAGGAPPLRRA
RLDPAGVVRQAVERLGHRHPDRAVRLELGPDLPEVEADAVLLRRALDNLLDNARKYSAPASPIRVEAARRGADLVVEVSD
RGEGIAAEELERVFSPFYRVDRSRARATGGVGLGLPLARRIAEAHGGTLTARSTPGEGTTLTLTIPGVR
>Mature_468_residues
SGGAGGGGPSRLGLRIYLVTVVAVLATGVAVLLALALARDRREPVRRDVMHAVARDAAARVATQWGSAGAIQEVIGPLAS
ALRVSVAVYGAGGEPVASAGEAMRPPLPPPPERERFTDRLGPGPPGAGGRERHVVSAVAPVVVAGAPVGFLVVAQQVPGG
RPPPVLLVLVALALVGAGVAAVVLGGSLARPLDRLARTARALGAGDLAARTGISRADELGAVARAFDEMADRVGALLRSS
TELMANVAHELRTPLARIRVALDLAAEGDADVARASLADIAEDLSELERLVDDVLASARLDLAGNGASSAGGAPPLRRAR
LDPAGVVRQAVERLGHRHPDRAVRLELGPDLPEVEADAVLLRRALDNLLDNARKYSAPASPIRVEAARRGADLVVEVSDR
GEGIAAEELERVFSPFYRVDRSRARATGGVGLGLPLARRIAEAHGGTLTARSTPGEGTTLTLTIPGVR

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=315, Percent_Identity=33.015873015873, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=30.0724637681159, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786783, Length=308, Percent_Identity=29.5454545454545, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789808, Length=293, Percent_Identity=30.0341296928328, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=30.0353356890459, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=33.0434782608696, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=26.3537906137184, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=29.8245614035088, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=29.4354838709677, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790551, Length=294, Percent_Identity=30.6122448979592, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=27.8761061946903, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082128, Length=311, Percent_Identity=26.6881028938907, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=28.75, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI145693157, Length=254, Percent_Identity=27.9527559055118, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=29.7413793103448, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=348, Percent_Identity=27.0114942528736, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=24.6808510638298, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=321, Percent_Identity=27.1028037383178, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48204; Mature: 48073

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGAGGGGPSRLGLRIYLVTVVAVLATGVAVLLALALARDRREPVRRDVMHAVARDAAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVATQWGSAGAIQEVIGPLASALRVSVAVYGAGGEPVASAGEAMRPPLPPPPERERFTDR
HHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCCCCCCCCCCHHHHHHH
LGPGPPGAGGRERHVVSAVAPVVVAGAPVGFLVVAQQVPGGRPPPVLLVLVALALVGAGV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHEEEHHCCCCCCHHHHHHHHHHHHHHCCH
AAVVLGGSLARPLDRLARTARALGAGDLAARTGISRADELGAVARAFDEMADRVGALLRS
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STELMANVAHELRTPLARIRVALDLAAEGDADVARASLADIAEDLSELERLVDDVLASAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLAGNGASSAGGAPPLRRARLDPAGVVRQAVERLGHRHPDRAVRLELGPDLPEVEADAV
CCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHH
LLRRALDNLLDNARKYSAPASPIRVEAARRGADLVVEVSDRGEGIAAEELERVFSPFYRV
HHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
DRSRARATGGVGLGLPLARRIAEAHGGTLTARSTPGEGTTLTLTIPGVR
HHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SGGAGGGGPSRLGLRIYLVTVVAVLATGVAVLLALALARDRREPVRRDVMHAVARDAAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVATQWGSAGAIQEVIGPLASALRVSVAVYGAGGEPVASAGEAMRPPLPPPPERERFTDR
HHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCCCCCCCCCCHHHHHHH
LGPGPPGAGGRERHVVSAVAPVVVAGAPVGFLVVAQQVPGGRPPPVLLVLVALALVGAGV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHEEEHHCCCCCCHHHHHHHHHHHHHHCCH
AAVVLGGSLARPLDRLARTARALGAGDLAARTGISRADELGAVARAFDEMADRVGALLRS
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STELMANVAHELRTPLARIRVALDLAAEGDADVARASLADIAEDLSELERLVDDVLASAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLAGNGASSAGGAPPLRRARLDPAGVVRQAVERLGHRHPDRAVRLELGPDLPEVEADAV
CCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHH
LLRRALDNLLDNARKYSAPASPIRVEAARRGADLVVEVSDRGEGIAAEELERVFSPFYRV
HHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
DRSRARATGGVGLGLPLARRIAEAHGGTLTARSTPGEGTTLTLTIPGVR
HHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]