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The map label for this gene is ackA [H]

Identifier: 220918185

GI number: 220918185

Start: 3411388

End: 3412665

Strand: Reverse

Name: ackA [H]

Synonym: A2cp1_3088

Alternate gene names: 220918185

Gene position: 3412665-3411388 (Counterclockwise)

Preceding gene: 220918187

Following gene: 220918184

Centisome position: 67.86

GC content: 71.83

Gene sequence:

>1278_bases
GTGATCGTTCTGGTGCTGAACTGCGGAAGCTCGTCGGCGAAGTTCGCGGTGATCGACGCCGTGACCGGCCGGGAGCTGGT
CTCCGGCGTGGCGCAGCGGGTCGGCTCGGCGCAGGCGACCCTCGACTTCAAGGTGGAGGGCAGGAAGGAGTCGCGCCTCC
TGCACGGCGCCGGGCACGAGCGGGCGCTGCGCGCGGTGGTCGAGCTCCTGGACGAGCTCGGGGTGGCCCACGAGATCGCC
GGCGTCGGGCACCGCGTCGTGCACGGCGGCGCCAAGTTCTCCGGATCGATGCCCATCACCCCCGCGGTGGTGGCGAAGAT
CGAGGAGTGCATCCCGCTCGGCCCGCTCCACAACCCGGCCAACCTGCTCGGCATCCGCATCGCCCAGGAGCTGTTCCCGG
CGCTGCCGCAAGTCGCGGTGTTCGACACCGCCTTCCACCAGACGATGCCGTCGCGCGCGTACCTGTACGCCGTGCCGTAC
GAGTGGTTCGCGAAGCACGAGGTGCGGCGGTACGGCTTCCACGGCACCAGCCACCGCTACGTGTCCCAGCAGGCGGTGAA
GCAGCTCGGCCTGGATCCGGAGGATCACGCGGTGGTCACGGCGCACCTCGGGAACGGCTGCTCGCTCGCCGCGGTCCGCA
ACGGCGCCAGCATGGACACGACCATGGGGCTCACCCCGGTGGACGGGGTGGTGATGGGCACGCGCAGCGGCAACATCGAC
CCGTCGATCATCGCGCACATGAAGAAGGCGCTGCACTGCACCGCCGACCACGTCATGGACGAGCTGAACCGGAACTCCGG
CCTGCTCGGCATCTCCGGCCTGTCGAACGACATGCGCACGCTGCAGGAGGCGGCCGCCGAAGGGCACGAGCGGGCCCAGC
TGGCCATCGACAAGTTCTGCTACTCCGTCGCGAAGGCCGCCGCGGGCATGTTCGTGTCGCTGGGGCGGGTGGACGCGCTC
GTGTTCACCGGCGGGATCGGGGAGAACGCGGTGGACGTCCGGGCCCGCATCGTGGAGCTGCTCGGGTTCGCGGGCTTCGC
GCTCGACGCCCACGCGAACGCGTTCCACGGCAAGGCGCTCCGGGGCCGGATCACCCGCACGACCAGCCCGATGGCCGCGG
TGATCGCCACGAACGAGGAGCTGATGATCGCGATGGACACCGCCGAGATCGCGTCCGCGCACGGGCACGTCGAGGCCCAC
GGCCAGGCGGGCGCCGCCCCCGCGGAGGGCGCCGGGGACGCCGAGCGGCCCGCCGCCGAGCGGCGCGCGTTCGCCTGA

Upstream 100 bases:

>100_bases
AGGCCATCGCGTCCGCGAGGCTTACGGCCCCAGCCCAAGTCCCGTCCAGACTCCGTGCCCGTCGGCGCGACGGAGCCCTC
ATCTCCTGGAGGTAGGTGGC

Downstream 100 bases:

>100_bases
GGGCCGGGGAGCGCACGCACATGGCCCATGTCCTCCTGCTCGCGCCGGCCGGGCGCCAGGTCGGCCTCACCACCGCCTGC
CTCGGCCTGGTCCGCGCCCT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MIVLVLNCGSSSAKFAVIDAVTGRELVSGVAQRVGSAQATLDFKVEGRKESRLLHGAGHERALRAVVELLDELGVAHEIA
GVGHRVVHGGAKFSGSMPITPAVVAKIEECIPLGPLHNPANLLGIRIAQELFPALPQVAVFDTAFHQTMPSRAYLYAVPY
EWFAKHEVRRYGFHGTSHRYVSQQAVKQLGLDPEDHAVVTAHLGNGCSLAAVRNGASMDTTMGLTPVDGVVMGTRSGNID
PSIIAHMKKALHCTADHVMDELNRNSGLLGISGLSNDMRTLQEAAAEGHERAQLAIDKFCYSVAKAAAGMFVSLGRVDAL
VFTGGIGENAVDVRARIVELLGFAGFALDAHANAFHGKALRGRITRTTSPMAAVIATNEELMIAMDTAEIASAHGHVEAH
GQAGAAPAEGAGDAERPAAERRAFA

Sequences:

>Translated_425_residues
MIVLVLNCGSSSAKFAVIDAVTGRELVSGVAQRVGSAQATLDFKVEGRKESRLLHGAGHERALRAVVELLDELGVAHEIA
GVGHRVVHGGAKFSGSMPITPAVVAKIEECIPLGPLHNPANLLGIRIAQELFPALPQVAVFDTAFHQTMPSRAYLYAVPY
EWFAKHEVRRYGFHGTSHRYVSQQAVKQLGLDPEDHAVVTAHLGNGCSLAAVRNGASMDTTMGLTPVDGVVMGTRSGNID
PSIIAHMKKALHCTADHVMDELNRNSGLLGISGLSNDMRTLQEAAAEGHERAQLAIDKFCYSVAKAAAGMFVSLGRVDAL
VFTGGIGENAVDVRARIVELLGFAGFALDAHANAFHGKALRGRITRTTSPMAAVIATNEELMIAMDTAEIASAHGHVEAH
GQAGAAPAEGAGDAERPAAERRAFA
>Mature_425_residues
MIVLVLNCGSSSAKFAVIDAVTGRELVSGVAQRVGSAQATLDFKVEGRKESRLLHGAGHERALRAVVELLDELGVAHEIA
GVGHRVVHGGAKFSGSMPITPAVVAKIEECIPLGPLHNPANLLGIRIAQELFPALPQVAVFDTAFHQTMPSRAYLYAVPY
EWFAKHEVRRYGFHGTSHRYVSQQAVKQLGLDPEDHAVVTAHLGNGCSLAAVRNGASMDTTMGLTPVDGVVMGTRSGNID
PSIIAHMKKALHCTADHVMDELNRNSGLLGISGLSNDMRTLQEAAAEGHERAQLAIDKFCYSVAKAAAGMFVSLGRVDAL
VFTGGIGENAVDVRARIVELLGFAGFALDAHANAFHGKALRGRITRTTSPMAAVIATNEELMIAMDTAEIASAHGHVEAH
GQAGAAPAEGAGDAERPAAERRAFA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=387, Percent_Identity=47.5452196382429, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=46.5, Blast_Score=337, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44799; Mature: 44799

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLVLNCGSSSAKFAVIDAVTGRELVSGVAQRVGSAQATLDFKVEGRKESRLLHGAGHE
CEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHCCCHH
RALRAVVELLDELGVAHEIAGVGHRVVHGGAKFSGSMPITPAVVAKIEECIPLGPLHNPA
HHHHHHHHHHHHHCHHHHHHHCCHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCH
NLLGIRIAQELFPALPQVAVFDTAFHQTMPSRAYLYAVPYEWFAKHEVRRYGFHGTSHRY
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHH
VSQQAVKQLGLDPEDHAVVTAHLGNGCSLAAVRNGASMDTTMGLTPVDGVVMGTRSGNID
HHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCC
PSIIAHMKKALHCTADHVMDELNRNSGLLGISGLSNDMRTLQEAAAEGHERAQLAIDKFC
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHH
YSVAKAAAGMFVSLGRVDALVFTGGIGENAVDVRARIVELLGFAGFALDAHANAFHGKAL
HHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHH
RGRITRTTSPMAAVIATNEELMIAMDTAEIASAHGHVEAHGQAGAAPAEGAGDAERPAAE
HCCEEECCCCEEEEEECCCCEEEEECHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHH
RRAFA
HCCCC
>Mature Secondary Structure
MIVLVLNCGSSSAKFAVIDAVTGRELVSGVAQRVGSAQATLDFKVEGRKESRLLHGAGHE
CEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHCCCHH
RALRAVVELLDELGVAHEIAGVGHRVVHGGAKFSGSMPITPAVVAKIEECIPLGPLHNPA
HHHHHHHHHHHHHCHHHHHHHCCHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCH
NLLGIRIAQELFPALPQVAVFDTAFHQTMPSRAYLYAVPYEWFAKHEVRRYGFHGTSHRY
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHH
VSQQAVKQLGLDPEDHAVVTAHLGNGCSLAAVRNGASMDTTMGLTPVDGVVMGTRSGNID
HHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCC
PSIIAHMKKALHCTADHVMDELNRNSGLLGISGLSNDMRTLQEAAAEGHERAQLAIDKFC
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHH
YSVAKAAAGMFVSLGRVDALVFTGGIGENAVDVRARIVELLGFAGFALDAHANAFHGKAL
HHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHH
RGRITRTTSPMAAVIATNEELMIAMDTAEIASAHGHVEAHGQAGAAPAEGAGDAERPAAE
HCCEEECCCCEEEEEECCCCEEEEECHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHH
RRAFA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]