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The map label for this gene is pta [H]

Identifier: 220918184

GI number: 220918184

Start: 3409223

End: 3411367

Strand: Reverse

Name: pta [H]

Synonym: A2cp1_3087

Alternate gene names: 220918184

Gene position: 3411367-3409223 (Counterclockwise)

Preceding gene: 220918185

Following gene: 220918183

Centisome position: 67.83

GC content: 75.76

Gene sequence:

>2145_bases
ATGGCCCATGTCCTCCTGCTCGCGCCGGCCGGGCGCCAGGTCGGCCTCACCACCGCCTGCCTCGGCCTGGTCCGCGCCCT
CGATCGCCAGGGCGTCCGGGTGGCGTTCGCGAAGCCCATCGCCGCGCGCGGCGAGGACCGCGTCTCCGCGCTGGTCCGGC
TCGGCTCCAGCCTGCGGCCGCCCGACCCGATCCCGCGCGCCCAGGCGGACGCGCTGCTCGCCTCCGGCGACGACCAGACG
CTGATGGAGCGGGTGGTGGCGCTCTGCGCCGGCGCGGCCGAGGGCGCGGACGTCCTGGTGGTCGCCGGGATGTGGCCCGA
GCCCGGGATGGTGCACTCGGCGCGGGTCAACGCGCTCATGCTGAAGGCGCTCGACGCGGAGCTGGTCCTGGTGGGCTCGC
CGCGCGGCGAGACGCCGGCGGAGCTGGCGGACGCGATGGCGATCGCGGCGCGCGGGCTCGGCGGGTTCTCCGACGGCGAG
CCGGTGAGCTGCTTCCTGAACCGCGTCGCCCCGAGGACGCCGGCCGCACGCGTCGGCGAGTCCCGGCCCATCTGGCTGGA
GGCGGGGGAGGAGGCTGAGCTCCCACCGGAGGAGATCGAGACCTACCGCACGGCGCTGGAGGCGGAGCGGCTCCGGCCGA
TCGCGGTGGTGCCCGCTCGGGGCGACCTCGCCGCGCCGCGCGTGAAGGACCTCGCCGAGGCCATCGGGGCGCGGGTCCTC
CGCGCGGGCGATCTCGAGGGCCGGCGCATCCGGCACGTGGCGCTGTGCGCCATGGCGGTGCCGGGCTCCATCAAGACGTT
CCGGCCCGGCACGCTCGTCATCACCCCGGGCGACCGGAGCGACATCCTGCTGGCCGCCGCGCTGGCCGTGCTGAACGGCG
TGCCGCTCGCGGGCGTGCTGCTCACCGGCGGTGTCGAGCCCGAGCCCCACGTCTTCGAGATGTGCGACTCCGCGCTCCGG
GCCGGGCTGCCGGTGCTCGCGGTGGAGCAGGGCAGCTACGCCGCCGCGACCGCGGTGGCGGGCATGAACCTCCAGGTGCC
GCCCGACGACCCCGCGCGCGTGGAGCGCGTGATGACGGCGGTGGCCGACCTCATCGACCCCGCCTGGCTGCGGTCCCGCG
CCGCGACGAGCCGCGTGCGGCGCCTCTCGCCGCCCGCGTTCCGGCAGCGGCTGGTGGAGGCGGCGCGCGCCGCGAACAAG
CGGATCGTCCTGCCGGAGGGCGCCGAGCCGCGCACGGTGGCCGCGGCGGCCATCGCCCAGGAGCGCGGGATCGCGCGCTG
CGTCCTGCTCGCCGACGCGGACGAGGTCCACGAGGTCGCGCGCCGGCAGGGGATCGCGCTGCCGCCGTCGATCGAGATCG
TCGATCCGGTGCGGGTCGCGCCCTGGTACGTGGCGCCGCTGGTGGAGCGGCGCGCGGCCAAGGGGATGACCGCGGCCCAG
GCCGCGCAGGAGCTGGGCGACGCCGTCATGGTCGGCACCATGATGATGGCGCTCGACGAGGCGGACGGGCTCGTCTCCGG
GGCGCTCCACACCACCGCCCACACCATCCGGCCCGCGCTGCAGATCGTGAAGACGGTGCCCGGCTGCGACCTGGTGTCGA
GCGTGTTCTTCATGTGCCTCCCGGAGCAGGTGCTGGTGTTCGGCGACTGCGCCGTGAACCCGACGCCCAGCCCCGAGCAG
CTCGCCGACATCGCGATCCAGAGCGCCGACTCGGCCGCCGCGTTCGGGATCGAGCCCCGCGTGGCGATGCTGTCCTACTC
GACCGGCACGAGCGGCGCGGGCGAGGAGGTCGAGAAGGTGAAGCGCGCGACCGAGCTCGCGCGCGCGGCGCGGCCGGACC
TCGCCATCGACGGGCCGCTGCAGTACGACGCGGCGGTCATGCCGGACGTGGCGCGCCAGAAGGCGCCGAAGTCGAGCGTG
GCCGGCCGCGCGACGGTGCTCGTGTTCCCGGACCTCAACACCGGGAACGTCACCTACAAGGCCGTGCAGCGGAGCGCGAA
CGTGGTCAGCATCGGCCCGATGCTGCAGGGGCTGGCCCGGCCGGTGAACGACCTGAGCCGCGGGTGCCTGGTCGAGGACA
TCGTCTTCACGATCGCGCTCACGGCCATCCAGGCGCAACAGCTGGCGGCGCGCCGGGCGCGCTGA

Upstream 100 bases:

>100_bases
ACGGCCAGGCGGGCGCCGCCCCCGCGGAGGGCGCCGGGGACGCCGAGCGGCCCGCCGCCGAGCGGCGCGCGTTCGCCTGA
GGGCCGGGGAGCGCACGCAC

Downstream 100 bases:

>100_bases
GGCACCGGGGCACGTCCGGGTGCGGGACGGCCGGGGCGTCCCGCCGAGGGCTGCTGGTGGCGGTGGCGGTCGAATGCGAG
GCGGCCGGCGCCGCGGGCGC

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MAHVLLLAPAGRQVGLTTACLGLVRALDRQGVRVAFAKPIAARGEDRVSALVRLGSSLRPPDPIPRAQADALLASGDDQT
LMERVVALCAGAAEGADVLVVAGMWPEPGMVHSARVNALMLKALDAELVLVGSPRGETPAELADAMAIAARGLGGFSDGE
PVSCFLNRVAPRTPAARVGESRPIWLEAGEEAELPPEEIETYRTALEAERLRPIAVVPARGDLAAPRVKDLAEAIGARVL
RAGDLEGRRIRHVALCAMAVPGSIKTFRPGTLVITPGDRSDILLAAALAVLNGVPLAGVLLTGGVEPEPHVFEMCDSALR
AGLPVLAVEQGSYAAATAVAGMNLQVPPDDPARVERVMTAVADLIDPAWLRSRAATSRVRRLSPPAFRQRLVEAARAANK
RIVLPEGAEPRTVAAAAIAQERGIARCVLLADADEVHEVARRQGIALPPSIEIVDPVRVAPWYVAPLVERRAAKGMTAAQ
AAQELGDAVMVGTMMMALDEADGLVSGALHTTAHTIRPALQIVKTVPGCDLVSSVFFMCLPEQVLVFGDCAVNPTPSPEQ
LADIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGEEVEKVKRATELARAARPDLAIDGPLQYDAAVMPDVARQKAPKSSV
AGRATVLVFPDLNTGNVTYKAVQRSANVVSIGPMLQGLARPVNDLSRGCLVEDIVFTIALTAIQAQQLAARRAR

Sequences:

>Translated_714_residues
MAHVLLLAPAGRQVGLTTACLGLVRALDRQGVRVAFAKPIAARGEDRVSALVRLGSSLRPPDPIPRAQADALLASGDDQT
LMERVVALCAGAAEGADVLVVAGMWPEPGMVHSARVNALMLKALDAELVLVGSPRGETPAELADAMAIAARGLGGFSDGE
PVSCFLNRVAPRTPAARVGESRPIWLEAGEEAELPPEEIETYRTALEAERLRPIAVVPARGDLAAPRVKDLAEAIGARVL
RAGDLEGRRIRHVALCAMAVPGSIKTFRPGTLVITPGDRSDILLAAALAVLNGVPLAGVLLTGGVEPEPHVFEMCDSALR
AGLPVLAVEQGSYAAATAVAGMNLQVPPDDPARVERVMTAVADLIDPAWLRSRAATSRVRRLSPPAFRQRLVEAARAANK
RIVLPEGAEPRTVAAAAIAQERGIARCVLLADADEVHEVARRQGIALPPSIEIVDPVRVAPWYVAPLVERRAAKGMTAAQ
AAQELGDAVMVGTMMMALDEADGLVSGALHTTAHTIRPALQIVKTVPGCDLVSSVFFMCLPEQVLVFGDCAVNPTPSPEQ
LADIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGEEVEKVKRATELARAARPDLAIDGPLQYDAAVMPDVARQKAPKSSV
AGRATVLVFPDLNTGNVTYKAVQRSANVVSIGPMLQGLARPVNDLSRGCLVEDIVFTIALTAIQAQQLAARRAR
>Mature_713_residues
AHVLLLAPAGRQVGLTTACLGLVRALDRQGVRVAFAKPIAARGEDRVSALVRLGSSLRPPDPIPRAQADALLASGDDQTL
MERVVALCAGAAEGADVLVVAGMWPEPGMVHSARVNALMLKALDAELVLVGSPRGETPAELADAMAIAARGLGGFSDGEP
VSCFLNRVAPRTPAARVGESRPIWLEAGEEAELPPEEIETYRTALEAERLRPIAVVPARGDLAAPRVKDLAEAIGARVLR
AGDLEGRRIRHVALCAMAVPGSIKTFRPGTLVITPGDRSDILLAAALAVLNGVPLAGVLLTGGVEPEPHVFEMCDSALRA
GLPVLAVEQGSYAAATAVAGMNLQVPPDDPARVERVMTAVADLIDPAWLRSRAATSRVRRLSPPAFRQRLVEAARAANKR
IVLPEGAEPRTVAAAAIAQERGIARCVLLADADEVHEVARRQGIALPPSIEIVDPVRVAPWYVAPLVERRAAKGMTAAQA
AQELGDAVMVGTMMMALDEADGLVSGALHTTAHTIRPALQIVKTVPGCDLVSSVFFMCLPEQVLVFGDCAVNPTPSPEQL
ADIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGEEVEKVKRATELARAARPDLAIDGPLQYDAAVMPDVARQKAPKSSVA
GRATVLVFPDLNTGNVTYKAVQRSANVVSIGPMLQGLARPVNDLSRGCLVEDIVFTIALTAIQAQQLAARRAR

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0280

COG function: function code C; Phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=720, Percent_Identity=49.8611111111111, Blast_Score=681, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=331, Percent_Identity=38.9728096676737, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788806, Length=332, Percent_Identity=31.0240963855422, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 74821; Mature: 74690

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVLLLAPAGRQVGLTTACLGLVRALDRQGVRVAFAKPIAARGEDRVSALVRLGSSLRP
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHHCCCCCC
PDPIPRAQADALLASGDDQTLMERVVALCAGAAEGADVLVVAGMWPEPGMVHSARVNALM
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
LKALDAELVLVGSPRGETPAELADAMAIAARGLGGFSDGEPVSCFLNRVAPRTPAARVGE
HEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHCCC
SRPIWLEAGEEAELPPEEIETYRTALEAERLRPIAVVPARGDLAAPRVKDLAEAIGARVL
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
RAGDLEGRRIRHVALCAMAVPGSIKTFRPGTLVITPGDRSDILLAAALAVLNGVPLAGVL
HCCCCCCCHHHHHHHHHHHCCCCCCEECCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHE
LTGGVEPEPHVFEMCDSALRAGLPVLAVEQGSYAAATAVAGMNLQVPPDDPARVERVMTA
EECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCEEECCCCCHHHHHHHHHH
VADLIDPAWLRSRAATSRVRRLSPPAFRQRLVEAARAANKRIVLPEGAEPRTVAAAAIAQ
HHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHH
ERGIARCVLLADADEVHEVARRQGIALPPSIEIVDPVRVAPWYVAPLVERRAAKGMTAAQ
HCCCEEEEEEECHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHH
AAQELGDAVMVGTMMMALDEADGLVSGALHTTAHTIRPALQIVKTVPGCDLVSSVFFMCL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PEQVLVFGDCAVNPTPSPEQLADIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGEEVEKV
CCHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHH
KRATELARAARPDLAIDGPLQYDAAVMPDVARQKAPKSSVAGRATVLVFPDLNTGNVTYK
HHHHHHHHHCCCCCEECCCCCCCCHHCCHHHHHCCCCCCCCCCEEEEEEECCCCCCEEHH
AVQRSANVVSIGPMLQGLARPVNDLSRGCLVEDIVFTIALTAIQAQQLAARRAR
HHHHCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHVLLLAPAGRQVGLTTACLGLVRALDRQGVRVAFAKPIAARGEDRVSALVRLGSSLRP
CEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHHCCCCCC
PDPIPRAQADALLASGDDQTLMERVVALCAGAAEGADVLVVAGMWPEPGMVHSARVNALM
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
LKALDAELVLVGSPRGETPAELADAMAIAARGLGGFSDGEPVSCFLNRVAPRTPAARVGE
HEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHCCC
SRPIWLEAGEEAELPPEEIETYRTALEAERLRPIAVVPARGDLAAPRVKDLAEAIGARVL
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
RAGDLEGRRIRHVALCAMAVPGSIKTFRPGTLVITPGDRSDILLAAALAVLNGVPLAGVL
HCCCCCCCHHHHHHHHHHHCCCCCCEECCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHE
LTGGVEPEPHVFEMCDSALRAGLPVLAVEQGSYAAATAVAGMNLQVPPDDPARVERVMTA
EECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCEEECCCCCHHHHHHHHHH
VADLIDPAWLRSRAATSRVRRLSPPAFRQRLVEAARAANKRIVLPEGAEPRTVAAAAIAQ
HHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHH
ERGIARCVLLADADEVHEVARRQGIALPPSIEIVDPVRVAPWYVAPLVERRAAKGMTAAQ
HCCCEEEEEEECHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHH
AAQELGDAVMVGTMMMALDEADGLVSGALHTTAHTIRPALQIVKTVPGCDLVSSVFFMCL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PEQVLVFGDCAVNPTPSPEQLADIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGEEVEKV
CCHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHH
KRATELARAARPDLAIDGPLQYDAAVMPDVARQKAPKSSVAGRATVLVFPDLNTGNVTYK
HHHHHHHHHCCCCCEECCCCCCCCHHCCHHHHHCCCCCCCCCCEEEEEEECCCCCCEEHH
AVQRSANVVSIGPMLQGLARPVNDLSRGCLVEDIVFTIALTAIQAQQLAARRAR
HHHHCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]