Click here to switch to the map view.

The map label for this gene is zraR [H]

Identifier: 220917653

GI number: 220917653

Start: 2833103

End: 2834326

Strand: Direct

Name: zraR [H]

Synonym: A2cp1_2554

Alternate gene names: 220917653

Gene position: 2833103-2834326 (Clockwise)

Preceding gene: 220917651

Following gene: 220917654

Centisome position: 56.33

GC content: 78.35

Gene sequence:

>1224_bases
ATGACGACGATCGCCACCACCGGGCCGGACGCAGCGCCGCAGCAGGGCCAGCACGGGCTCGTGTTCGGCCCCGGCAGCCC
GCTCGGCGCGCTGGTGCGGACCTGCGAGCGCATCGCGCGGAGCGAGGCGACGGTGCTGCTGACGGGCGAGACCGGCACGG
GCAAGGAGGTGTTCGCGCGCGCCATCCACGCCGCGAGCCCGCGCGCGGCGCGGCCGCTGGTCCCGGTGAACTGCGGCGCC
ATCCCGGAGGCGTTGCTGGAGAGCGAGCTGTTCGGCCACGTGCGCGGCGCGTTCACCGGCGCGATGGCCTCGCGGCGCGG
GCGGGTGGCGGCCGCCGAGGGCGGCACGCTGTTCCTCGACGAGGTGGGCGAGCTGCCGCTGGCGCTCCAGGTCAAGCTGC
TGCGCGTCCTCCAGGAGCGGACCTACGAGCCGGTGGGCTCGACCGAGGCGGTCCCCGCCGACTTTCGCCTGGTGGCCGCC
ACCAACCGCGATCTCTCCGCCGAGGTGGCCGCCGGCCGCTTCCGCCGCGACCTCTACTACCGCCTGCTGGTCTGCCCGCT
CGAGATCCCGCCGCTCCGCGCGCGGAAGGGCGACGCGCTGCGCCTGTTCCAGCACTTCTGGGCCGCGCGCGGGGAGCGCC
GTCCGCTCGAGCCCGAGGTGGCGGAGGCGCTCGCCGCCTACGACTGGCCGGGCAACGTCCGCGAGCTGGAGAACCTGGTG
GAGCGGCTCTCGGTCTGCGCCGAGGGCGCCGTCATCCGCGTGGCCGACCTCCCGGTCGCGCTGCGCTGCCGCCGCGCGAA
CGACGCGGCGCGCGCGCTCGCCCTCCCCGCGGCCCCGGCGTCCGAGGACGCGCCGGCGTCGATCCCGGCCCGCGCCGCGG
AAGGCGACGCGGCGCCCCCGCCGGCGCCGGGGGACAGCGCCGCCGCGGCGCCCGCCACCGCGGGGGAGGCGATCGACCCG
GCCGTGCTGCGCGCCCTGACGGCGGAGGACGCGCCCCCGCCTGCCGAACCGACCTTCGACGCCGGCCGGCCGGTGGACCT
GCCCGGCCTGCTGCGGCGCCTGGAGGACGCGTACATCTCGGCTGCGCTGGCGCGGACCGGCGGCAACAAGAAGGCGGCGG
CCGACCTGCTGGGGCTGCAGCGCACCACGCTGGTGGAGAAGCTGCGCCGCCGCAGCCGCGAGGCGATCGCCGCGGCGCCG
ACGGCCCACGCCGCCCAGGCCTGA

Upstream 100 bases:

>100_bases
ATCGCGTGACGCCCGGGACGTGACGCGTTGGCCCCGACCTTGCTCTGGCGCCAGCCGAGCGACGCGCCCCCCAGCGTCGC
GACGAGAAGGAGCCAACGCC

Downstream 100 bases:

>100_bases
GCACGCGTGACGCCCGCCGCCGTCCTCCTGGCGCTCGCCGCCTCGGCGCCGCCGCCGCTCGCCCTCACCGTCTCGGCCGA
GCGCATCGCGCTCCCCGCCG

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTTIATTGPDAAPQQGQHGLVFGPGSPLGALVRTCERIARSEATVLLTGETGTGKEVFARAIHAASPRAARPLVPVNCGA
IPEALLESELFGHVRGAFTGAMASRRGRVAAAEGGTLFLDEVGELPLALQVKLLRVLQERTYEPVGSTEAVPADFRLVAA
TNRDLSAEVAAGRFRRDLYYRLLVCPLEIPPLRARKGDALRLFQHFWAARGERRPLEPEVAEALAAYDWPGNVRELENLV
ERLSVCAEGAVIRVADLPVALRCRRANDAARALALPAAPASEDAPASIPARAAEGDAAPPPAPGDSAAAAPATAGEAIDP
AVLRALTAEDAPPPAEPTFDAGRPVDLPGLLRRLEDAYISAALARTGGNKKAAADLLGLQRTTLVEKLRRRSREAIAAAP
TAHAAQA

Sequences:

>Translated_407_residues
MTTIATTGPDAAPQQGQHGLVFGPGSPLGALVRTCERIARSEATVLLTGETGTGKEVFARAIHAASPRAARPLVPVNCGA
IPEALLESELFGHVRGAFTGAMASRRGRVAAAEGGTLFLDEVGELPLALQVKLLRVLQERTYEPVGSTEAVPADFRLVAA
TNRDLSAEVAAGRFRRDLYYRLLVCPLEIPPLRARKGDALRLFQHFWAARGERRPLEPEVAEALAAYDWPGNVRELENLV
ERLSVCAEGAVIRVADLPVALRCRRANDAARALALPAAPASEDAPASIPARAAEGDAAPPPAPGDSAAAAPATAGEAIDP
AVLRALTAEDAPPPAEPTFDAGRPVDLPGLLRRLEDAYISAALARTGGNKKAAADLLGLQRTTLVEKLRRRSREAIAAAP
TAHAAQA
>Mature_406_residues
TTIATTGPDAAPQQGQHGLVFGPGSPLGALVRTCERIARSEATVLLTGETGTGKEVFARAIHAASPRAARPLVPVNCGAI
PEALLESELFGHVRGAFTGAMASRRGRVAAAEGGTLFLDEVGELPLALQVKLLRVLQERTYEPVGSTEAVPADFRLVAAT
NRDLSAEVAAGRFRRDLYYRLLVCPLEIPPLRARKGDALRLFQHFWAARGERRPLEPEVAEALAAYDWPGNVRELENLVE
RLSVCAEGAVIRVADLPVALRCRRANDAARALALPAAPASEDAPASIPARAAEGDAAPPPAPGDSAAAAPATAGEAIDPA
VLRALTAEDAPPPAEPTFDAGRPVDLPGLLRRLEDAYISAALARTGGNKKAAADLLGLQRTTLVEKLRRRSREAIAAAPT
AHAAQA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=251, Percent_Identity=51.394422310757, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87082117, Length=241, Percent_Identity=51.8672199170125, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1788550, Length=251, Percent_Identity=48.207171314741, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI1788905, Length=235, Percent_Identity=49.7872340425532, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789087, Length=245, Percent_Identity=48.9795918367347, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87082152, Length=244, Percent_Identity=50.8196721311475, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789233, Length=236, Percent_Identity=48.728813559322, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1790299, Length=376, Percent_Identity=38.2978723404255, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1786524, Length=245, Percent_Identity=45.3061224489796, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081872, Length=245, Percent_Identity=41.6326530612245, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787583, Length=235, Percent_Identity=40.8510638297872, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789828, Length=240, Percent_Identity=37.9166666666667, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI87081858, Length=255, Percent_Identity=34.5098039215686, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 42676; Mature: 42545

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIATTGPDAAPQQGQHGLVFGPGSPLGALVRTCERIARSEATVLLTGETGTGKEVFAR
CCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
AIHAASPRAARPLVPVNCGAIPEALLESELFGHVRGAFTGAMASRRGRVAAAEGGTLFLD
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEC
EVGELPLALQVKLLRVLQERTYEPVGSTEAVPADFRLVAATNRDLSAEVAAGRFRRDLYY
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
RLLVCPLEIPPLRARKGDALRLFQHFWAARGERRPLEPEVAEALAAYDWPGNVRELENLV
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
ERLSVCAEGAVIRVADLPVALRCRRANDAARALALPAAPASEDAPASIPARAAEGDAAPP
HHHHHHHCCCEEEEECCCEEEEECCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCC
PAPGDSAAAAPATAGEAIDPAVLRALTAEDAPPPAEPTFDAGRPVDLPGLLRRLEDAYIS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AALARTGGNKKAAADLLGLQRTTLVEKLRRRSREAIAAAPTAHAAQA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
TTIATTGPDAAPQQGQHGLVFGPGSPLGALVRTCERIARSEATVLLTGETGTGKEVFAR
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
AIHAASPRAARPLVPVNCGAIPEALLESELFGHVRGAFTGAMASRRGRVAAAEGGTLFLD
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEC
EVGELPLALQVKLLRVLQERTYEPVGSTEAVPADFRLVAATNRDLSAEVAAGRFRRDLYY
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
RLLVCPLEIPPLRARKGDALRLFQHFWAARGERRPLEPEVAEALAAYDWPGNVRELENLV
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
ERLSVCAEGAVIRVADLPVALRCRRANDAARALALPAAPASEDAPASIPARAAEGDAAPP
HHHHHHHCCCEEEEECCCEEEEECCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCC
PAPGDSAAAAPATAGEAIDPAVLRALTAEDAPPPAEPTFDAGRPVDLPGLLRRLEDAYIS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AALARTGGNKKAAADLLGLQRTTLVEKLRRRSREAIAAAPTAHAAQA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]