Click here to switch to the map view.

The map label for this gene is trg [H]

Identifier: 220917589

GI number: 220917589

Start: 2748891

End: 2750480

Strand: Direct

Name: trg [H]

Synonym: A2cp1_2489

Alternate gene names: 220917589

Gene position: 2748891-2750480 (Clockwise)

Preceding gene: 220917588

Following gene: 220917592

Centisome position: 54.66

GC content: 75.53

Gene sequence:

>1590_bases
ATGGTTCGCAACTGGAAGATCTCCACGCGGCTCACCGCCGCCTTCGCCGGGCTCATCGCCACGGCGGTCGCGGTGGGCGC
CATGGGCGTGTCGCGCATGGAGGTCCAGTCGCGGGCGCTGGAGCGGCTGGTGAGCCAGCGCTACGAGCTGGTGGAGCGGG
CGGGCGTCTGCGTGCAGACCACCGAGTCGAGCACGCGCGCGAGCTGGCAGCAGTTCCTGTTCGCCGGGATCTACACGCCG
GCGCAGATGGACGGGCTGCGCGCGATCCTCGCGAAGAACAAGCGCGAGTGCTCGGCCGCGATCGCCTGGCTCGAGGGCGC
GCTCACCACGCCGGAGGAGCGCGACCTGTACCGCCGCGTGGGTGAGCTGCGCGGGCCCTACCAGGCGACGCGCGACGAGG
TCGCGAAGGCGTTCGCGGACGGGCGGCGCGAGGAGGCTGCGGCGCTCTTCCAGCGCGAGCTGATGCCGCGGCTCGAGGCC
TACCGCCAGGGCTGGATGGACCTGGTGGCGCTGGAGAAGCGCTACATGATCGAGACGGTGGAGCAGGAAGCGGAGCGGAC
CCGCGTCGCCCGCCTCGGCATCGCCGGCATCACGGCGTTCGCGCTGCTCCTCGCCGCCGGGGTGGCATTCGTGATCGCGC
GCAGCATCGTGCAGCCGCTGGCGGGCGTGGCGGGCGTCGCGTCGCGGATCGCCGACGGCGACCTCACCGCGCGGATCGCG
CCGCACGGGCGCGACGAGATCGCGACGCTGGAGGACGCGATGCGCGGCATGACCGAGCGGCTGGCGGGGGTGCTGGGCGA
GGTCCGCGGCGGCGCCGACGCGCTCGCGTCCGCCGCAGGCCAGGTGTCCGCCACCTCGCAGGCGCTCTCGCAGGGCACCG
GCGAGCAGTCCGCCTCGGTGGAGGAGACCACGGCCAGCCTGGAGGAGATGAGCGCGTCCATCGACACCAACTCGCGCAAC
GGCCGGGAGGCGGAGCGCATCGCGGCCGCCGGCGCGGTGGACGCCGAGGCCTGCGGCCGCGCCGCCGCGGAGGCGGCCGA
GGCGATGCGCGCCATCGTCGAGCGGATCGGGATCGTGGAGGAGATCGCCTACCAGACCAACCTGCTCGCCCTGAACGCCG
CCATCGAGGCGGCGCGCGCCGGCGAGCAGGGGCGCGGCTTCGCGGTGGTGGCGGCCGAGGTCCGGAAGCTCGCCGTGCGC
AGCCAGACGGCCTCGGCCGAGATCGGTGGCCTCGCCTCGCGCTCGATGGAGAGCGCCGCCCGCAGCGGCGAGCTGCTCAA
CGCGCTCGTCCCCACCATCCAGCGCACCGCCGCGCTGGTGCAGGCCGTCGCCGCGGCCGGCCAGGAACAGGCGGCGGGCG
TCGCCCAGATCAACGGCGCGATGCGGCGCGTGGACGACGTCGCGCAGCGGAACGCTTCGGCCTCCGAGGAGCTCGCCTCG
ACCGCCGAGGAGCTGAGCACGCAGGCCGAGGCGCTGCAGGCGCTCGTCGCGGTGTTCCGGCTCGACGGCACGGGCGCGCG
GCCGGCGGCGCGCGCCGAGCCGCCGCGGCAGCAGCCGGCGCGGCCGCTGCTCGCGGCGACGAGCCGCTAG

Upstream 100 bases:

>100_bases
GCGGAATACCGCCTCCCCTCCTCGCCCCTTCTGCGCGAAACCTTCGCCCCCCGATCGCAGCACGCGCGGCTCCCGTCGCG
CGCCGCCGGAGCCGCCCGCC

Downstream 100 bases:

>100_bases
CCGGAGGCGCCTGCGTCCGCCCGGAGCGGCCCCTCGCCTGCGGGCGCGCGCCGCGGCGCCGCGGCGGCGTCCCGCAGGTG
CCCCTCCAGCACCGCCATCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MVRNWKISTRLTAAFAGLIATAVAVGAMGVSRMEVQSRALERLVSQRYELVERAGVCVQTTESSTRASWQQFLFAGIYTP
AQMDGLRAILAKNKRECSAAIAWLEGALTTPEERDLYRRVGELRGPYQATRDEVAKAFADGRREEAAALFQRELMPRLEA
YRQGWMDLVALEKRYMIETVEQEAERTRVARLGIAGITAFALLLAAGVAFVIARSIVQPLAGVAGVASRIADGDLTARIA
PHGRDEIATLEDAMRGMTERLAGVLGEVRGGADALASAAGQVSATSQALSQGTGEQSASVEETTASLEEMSASIDTNSRN
GREAERIAAAGAVDAEACGRAAAEAAEAMRAIVERIGIVEEIAYQTNLLALNAAIEAARAGEQGRGFAVVAAEVRKLAVR
SQTASAEIGGLASRSMESAARSGELLNALVPTIQRTAALVQAVAAAGQEQAAGVAQINGAMRRVDDVAQRNASASEELAS
TAEELSTQAEALQALVAVFRLDGTGARPAARAEPPRQQPARPLLAATSR

Sequences:

>Translated_529_residues
MVRNWKISTRLTAAFAGLIATAVAVGAMGVSRMEVQSRALERLVSQRYELVERAGVCVQTTESSTRASWQQFLFAGIYTP
AQMDGLRAILAKNKRECSAAIAWLEGALTTPEERDLYRRVGELRGPYQATRDEVAKAFADGRREEAAALFQRELMPRLEA
YRQGWMDLVALEKRYMIETVEQEAERTRVARLGIAGITAFALLLAAGVAFVIARSIVQPLAGVAGVASRIADGDLTARIA
PHGRDEIATLEDAMRGMTERLAGVLGEVRGGADALASAAGQVSATSQALSQGTGEQSASVEETTASLEEMSASIDTNSRN
GREAERIAAAGAVDAEACGRAAAEAAEAMRAIVERIGIVEEIAYQTNLLALNAAIEAARAGEQGRGFAVVAAEVRKLAVR
SQTASAEIGGLASRSMESAARSGELLNALVPTIQRTAALVQAVAAAGQEQAAGVAQINGAMRRVDDVAQRNASASEELAS
TAEELSTQAEALQALVAVFRLDGTGARPAARAEPPRQQPARPLLAATSR
>Mature_529_residues
MVRNWKISTRLTAAFAGLIATAVAVGAMGVSRMEVQSRALERLVSQRYELVERAGVCVQTTESSTRASWQQFLFAGIYTP
AQMDGLRAILAKNKRECSAAIAWLEGALTTPEERDLYRRVGELRGPYQATRDEVAKAFADGRREEAAALFQRELMPRLEA
YRQGWMDLVALEKRYMIETVEQEAERTRVARLGIAGITAFALLLAAGVAFVIARSIVQPLAGVAGVASRIADGDLTARIA
PHGRDEIATLEDAMRGMTERLAGVLGEVRGGADALASAAGQVSATSQALSQGTGEQSASVEETTASLEEMSASIDTNSRN
GREAERIAAAGAVDAEACGRAAAEAAEAMRAIVERIGIVEEIAYQTNLLALNAAIEAARAGEQGRGFAVVAAEVRKLAVR
SQTASAEIGGLASRSMESAARSGELLNALVPTIQRTAALVQAVAAAGQEQAAGVAQINGAMRRVDDVAQRNASASEELAS
TAEELSTQAEALQALVAVFRLDGTGARPAARAEPPRQQPARPLLAATSR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=346, Percent_Identity=36.9942196531792, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1788194, Length=370, Percent_Identity=34.8648648648649, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=37.8461538461538, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=36.1194029850746, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=30.6748466257669, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55785; Mature: 55785

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRNWKISTRLTAAFAGLIATAVAVGAMGVSRMEVQSRALERLVSQRYELVERAGVCVQT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TESSTRASWQQFLFAGIYTPAQMDGLRAILAKNKRECSAAIAWLEGALTTPEERDLYRRV
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GELRGPYQATRDEVAKAFADGRREEAAALFQRELMPRLEAYRQGWMDLVALEKRYMIETV
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQEAERTRVARLGIAGITAFALLLAAGVAFVIARSIVQPLAGVAGVASRIADGDLTARIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PHGRDEIATLEDAMRGMTERLAGVLGEVRGGADALASAAGQVSATSQALSQGTGEQSASV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
EETTASLEEMSASIDTNSRNGREAERIAAAGAVDAEACGRAAAEAAEAMRAIVERIGIVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAYQTNLLALNAAIEAARAGEQGRGFAVVAAEVRKLAVRSQTASAEIGGLASRSMESAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGELLNALVPTIQRTAALVQAVAAAGQEQAAGVAQINGAMRRVDDVAQRNASASEELAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TAEELSTQAEALQALVAVFRLDGTGARPAARAEPPRQQPARPLLAATSR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MVRNWKISTRLTAAFAGLIATAVAVGAMGVSRMEVQSRALERLVSQRYELVERAGVCVQT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TESSTRASWQQFLFAGIYTPAQMDGLRAILAKNKRECSAAIAWLEGALTTPEERDLYRRV
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GELRGPYQATRDEVAKAFADGRREEAAALFQRELMPRLEAYRQGWMDLVALEKRYMIETV
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQEAERTRVARLGIAGITAFALLLAAGVAFVIARSIVQPLAGVAGVASRIADGDLTARIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PHGRDEIATLEDAMRGMTERLAGVLGEVRGGADALASAAGQVSATSQALSQGTGEQSASV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
EETTASLEEMSASIDTNSRNGREAERIAAAGAVDAEACGRAAAEAAEAMRAIVERIGIVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAYQTNLLALNAAIEAARAGEQGRGFAVVAAEVRKLAVRSQTASAEIGGLASRSMESAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGELLNALVPTIQRTAALVQAVAAAGQEQAAGVAQINGAMRRVDDVAQRNASASEELAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TAEELSTQAEALQALVAVFRLDGTGARPAARAEPPRQQPARPLLAATSR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]